SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSRNOP00000037549 from Rattus norvegicus 76_5.0

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSRNOP00000037549
Domain Number 1 Region: 334-528
Classification Level Classification E-value
Superfamily Hemopexin-like domain 7.85e-63
Family Hemopexin-like domain 5.33e-06
Further Details:      
 
Domain Number 2 Region: 101-293
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 2.45e-44
Family Matrix metalloproteases, catalytic domain 4.95e-05
Further Details:      
 
Domain Number 3 Region: 41-114
Classification Level Classification E-value
Superfamily PGBD-like 4.71e-17
Family MMP N-terminal domain 0.0037
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSRNOP00000037549   Gene: ENSRNOG00000023643   Transcript: ENSRNOT00000035881
Sequence length 587
Comment pep:known chromosome:Rnor_5.0:12:32636907:32663678:-1 gene:ENSRNOG00000023643 transcript:ENSRNOT00000035881 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MGRRPRGPGSPRGPGPPRPGPGLPPLLLMLALAAHGGCAAPAPRAEDLSLGVEWLSKFGY
LPPADPATGQLQTQEELSKAITAMQQFGGLETTGILDEATLALMKTPRCSLPDLPLGAQS
RRRRQTPLPTKWSKRNLSWRVRTFPRDSPLGRDTVRALMYYALKVWSDITPLNFHEVAGN
MADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGDHHTAGDTHFDDDEAWTFRSSDAHGMD
LFAVAVHEFGHAIGLSHVAAPSSIMQPYYQGPVGDPLRYGLPYEDRVRVWQLYGVRESVS
PTAQLDTPEPEEPPLLPEPPNNRSSTPPQKDVPHRCTAHFDAVAQIRGEAFFFKGKYFWR
LTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEG
YPRPVSDFSLPPGGIDAVFSWAHNDRTYFFKDQLYWRYDDHTRRMDPGYPAQGPLWRGVP
SVLDDAMRWSDGASYFFRGQEYWKVLDGELEAAPGYPQSTARDWLVCGEQLADAEDVGPG
PQGRSGAQDGLAVCSCTSDAHRSALPPLLLLPPLLWGLWTSVSSTAS
Download sequence
Identical sequences D3ZXJ0
ENSRNOP00000037549 10116.ENSRNOP00000037549 ENSRNOP00000037549

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