SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSMMUP00000004544 from Macaca mulatta 76_1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSMMUP00000004544
Domain Number 1 Region: 100-264
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 3.08e-56
Family Matrix metalloproteases, catalytic domain 0.0000000558
Further Details:      
 
Domain Number 2 Region: 26-95
Classification Level Classification E-value
Superfamily PGBD-like 1.1e-19
Family MMP N-terminal domain 0.0011
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
nucleoplasm part 1.496 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSMMUP00000004544   Gene: ENSMMUG00000003405   Transcript: ENSMMUT00000004818
Sequence length 270
Comment pep:known chromosome:MMUL_1:14:101110166:101120818:-1 gene:ENSMMUG00000003405 transcript:ENSMMUT00000004818 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MAAMRLTVLCAVCLLPGSLALPLPREAGGMSELQWKQAQDYLKRFYLYDSETKNANSLEA
KLKEMEKFFGLPITGMLNSRIIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYT
RDLPHFTVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDPYPFDGPGNTLA
HAFAPGPGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYG
NGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
Download sequence
Identical sequences F7FE85 G7PNJ9
ENSMMUP00000004544 ENSMMUP00000004544 9544.ENSMMUP00000004544

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