SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSMMUP00000004544 from Macaca mulatta 76_1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSMMUP00000004544
Domain Number 1 Region: 100-264
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 3.08e-56
Family Matrix metalloproteases, catalytic domain 5.58e-08
Further Details:      
 
Domain Number 2 Region: 26-95
Classification Level Classification E-value
Superfamily PGBD-like 1.1e-19
Family MMP N-terminal domain 0.0011
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74
nucleoplasm part 1.418 5.58

Protein sequence

External link(s) Protein: ENSMMUP00000004544   Gene: ENSMMUG00000003405   Transcript: ENSMMUT00000004818
Sequence length 270
Comment pep:known chromosome:MMUL_1:14:101110166:101120818:-1 gene:ENSMMUG00000003405 transcript:ENSMMUT00000004818 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MAAMRLTVLCAVCLLPGSLALPLPREAGGMSELQWKQAQDYLKRFYLYDSETKNANSLEA
KLKEMEKFFGLPITGMLNSRIIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYT
RDLPHFTVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDPYPFDGPGNTLA
HAFAPGPGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYG
NGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
Download sequence
Identical sequences F7FE85 G7PNJ9
9544.ENSMMUP00000004544 ENSMMUP00000004544 ENSMMUP00000004544

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