SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for YDL066W from Saccharomyces cerevisiae SGD

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YDL066W
Domain Number 1 Region: 17-424
Classification Level Classification E-value
Superfamily Isocitrate/Isopropylmalate dehydrogenase-like 8.64e-151
Family Dimeric isocitrate & isopropylmalate dehydrogenases 1.29e-10
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
mitochondrial matrix 1.707 8.12
microtubule cytoskeleton 1.334 7.51
microtubule associated complex 1.999 7.51
plastid 1.598 6.34
chloroplast part 1.897 6.34
plastid stroma 2.025 6.23
microbody 1.956 4.72
lipid particle 1.526 4.16

Protein sequence

External link(s) Locus: YDL066W   Protein: S000002224
Sequence length 428
Comment IDP1 SGDID:S000002224, Chr IV from 334835-336121, Verified ORF, "Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes"
Sequence
MSMLSRRLFSTSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDL
SVESRDATSDKITQDAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILG
GTVFREPIVIPRIPRLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTA
QPQTLKVYDYKGSGVAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRF
KDIFQEVYEAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQ
GFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKR
GELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKRL
QKEIKSIE
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Identical sequences A6ZXR0 B3LGW3 B5VFK1 C7GJP4 C8Z4K3 G2WC95 N1P7R0 P21954
YDL066W YDL066W YDL066W YDL066W YDL066W YDL066W YDL066W YDL066W YDL066W YDL066W YDL066W 4932.YDL066W YDL066W SCRT_00564 YDL066W tr|A6ZXR0|A6ZXR0_YEAS7 YDL066W YDL066W YDL066W YDL066W YDL066W

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