SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for YDR075W from Saccharomyces cerevisiae SGD

Domain architecture

Domain assignment details

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Strong hits

Sequence:  YDR075W
Domain Number 1 Region: 1-288
Classification Level Classification E-value
Superfamily Metallo-dependent phosphatases 1.3e-114
Family Protein serine/threonine phosphatase 0.0000000263
Further Details:      

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
endoplasmic reticulum part 1.429 25.02
Molecular Function IC (bits) H-Score
ribonuclease activity 1.944 70.66
nuclease activity 1.722 70.66
phosphoric ester hydrolase activity 1.595 67.22
calmodulin binding 2.019 28.11
phospholipid binding 1.516 27.97
drug binding 2.13 25.82
phosphatase binding 2.005 25.7
phosphoric diester hydrolase activity 1.902 12.21
phospholipase activity 2.012 7.38
calcium ion binding 1.343 6.23

Protein sequence

External link(s) Locus: YDR075W   Protein: S000002482
Sequence length 308
Comment PPH3 SGDID:S000002482, Chr IV from 597154-598080, Verified ORF, "Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p"
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Identical sequences A6ZY40 B3LGJ5 B5VFX1 C7GVR2 C8Z4Z3 G2WAH9 H0GE33 P32345 W7PNV8
YDR075W YDR075w___KOG0372 YDR075W YDR075W YDR075W YDR075W 4932.YDR075W YDR075W YDR075W YDR075W YDR075W YDR075W YDR075W YDR075W tr|A6ZY40|A6ZY40_YEAS7 YDR075W SCRT_00440 YDR075W YDR075W YDR075W

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