SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for YDR075W from Saccharomyces cerevisiae SGD

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YDR075W
Domain Number 1 Region: 1-288
Classification Level Classification E-value
Superfamily Metallo-dependent phosphatases 1.3e-114
Family Protein serine/threonine phosphatase 0.0000000263
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
endoplasmic reticulum part 1.431 25.02
Molecular Function IC (bits) H-Score
nuclease activity 1.69 70.67
ribonuclease activity 1.939 70.67
phosphoric ester hydrolase activity 1.596 67.74
calmodulin binding 2.02 28.15
phospholipid binding 1.517 27.98
drug binding 2.131 25.83
phosphatase binding 1.998 25.61
phosphoric diester hydrolase activity 1.903 12.21
iron ion binding 2.227 7.41
phospholipase activity 2.013 7.38

Protein sequence

External link(s) Locus: YDR075W   Protein: S000002482
Sequence length 308
Comment PPH3 SGDID:S000002482, Chr IV from 597154-598080, Verified ORF, "Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p"
Sequence
MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLL
TLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKV
YGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRK
QEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVME
GYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQNEVGNAIIPTK
KSQMDYFL
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Identical sequences A6ZY40 B3LGJ5 B5VFX1 C7GVR2 C8Z4Z3 G2WAH9 H0GE33 P32345 W7PNV8
YDR075W YDR075W YDR075W YDR075W YDR075W SCRT_00440 YDR075W YDR075W YDR075W YDR075W YDR075W YDR075W YDR075W YDR075w___KOG0372 YDR075W YDR075W tr|A6ZY40|A6ZY40_YEAS7 4932.YDR075W YDR075W YDR075W

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