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Domain assignment for YER133W from Saccharomyces cerevisiae SGD

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YER133W
Domain Number 1 Region: 22-300
Classification Level Classification E-value
Superfamily Metallo-dependent phosphatases 1.9e-117
Family Protein serine/threonine phosphatase 0.000000000203
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
phosphoric ester hydrolase activity 1.483 72.54
nuclease activity 1.579 63.92
calmodulin binding 2.015 28.36
phosphatase binding 1.968 25.83
drug binding 2.015 24.2
phospholipid binding 1.435 13.26
phospholipase activity 1.953 11.66
phosphoric diester hydrolase activity 1.845 11.61
manganese ion binding 2.129 7.86
iron ion binding 2.108 6.92

Protein sequence

External link(s) Locus: YER133W   Protein: S000000935
Sequence length 312
Comment GLC7 SGDID:S000000935, Chr V from 432491-432667,433193-433954, Verified ORF, "Catalytic subunit of type 1 serine/threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p"
Sequence
MDSQPVDVDNIIDRLLEVRGSKPGQQVDLEENEIRYLCSKARSIFIKQPILLELEAPIKI
CGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFIL
RGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLN
SMEQIRRVMRPTDIPDVGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVNRFLQKQDM
ELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAQK
SLPRQAGGRKKK
Download sequence
Identical sequences A6ZR87 B3LRP8 C8Z7F0 G2WCZ2 N1P3L5 P32598
tr|A6ZR87|A6ZR87_YEAS7 YER133W YER133W 4932.YER133W YER133W YER133W YER133W YER133W YER133W YER133W CX00019 YER133W YER133W YER133W YER133W YER133W YER133W YER133W YER133W YER133W YER133W YER133W YER133W SCRT_04610 YER133W

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