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Domain assignment for YGL136C from Saccharomyces cerevisiae SGD

Domain architecture

Domain assignment details

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Strong hits

Sequence:  YGL136C
Domain Number 1 Region: 14-121,196-310
Classification Level Classification E-value
Superfamily S-adenosyl-L-methionine-dependent methyltransferases 4.94e-26
Family RNA methyltransferase FtsJ 0.0014
Further Details:      

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
host cell part 1.994 16.09
transferase complex 1.368 14.11
nucleoplasm part 1.368 12.76
methyltransferase complex 2.142 12.31
nuclear transcription factor complex 2.014 8.84
nucleolus 1.731 8.58
organelle envelope 1.404 7.29
chromosomal part 1.463 7.04
trans-Golgi network 1.764 6.25
Biological Process IC (bits) H-Score
macromolecule methylation 1.881 111.38
protein alkylation 2.119 72.99
RNA modification 2.218 68.33
mRNA metabolic process 1.678 35.07
mRNA processing 1.845 35.07
ncRNA processing 1.837 34.74
RNA processing 1.499 31.57
ncRNA metabolic process 1.49 31.13
DNA modification 1.95 28.47
peptidyl-amino acid modification 1.432 26.67

Protein sequence

External link(s) Locus: YGL136C   Protein: S000003104
Sequence length 320
Comment MRM2 SGDID:S000003104, Chr VII from 253864-252902, reverse complement, Verified ORF, "Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ"
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Identical sequences A0A0L8VQQ7 B3LHJ4 C7GPR6 C8Z8B4 E7KCE1 E7KNB2 E7LU84 E7NHJ2 E7QEL2 H0GFU4 N1P3D6 P53123
4932.YGL136C YGL136C YGL136C YGL136C YGL136C YGL136C YGL136C SCRT_01130 YGL136C YGL136C YGL136C YGL136C NP_011379.1.97178 YGL136C YGL136C YGL136C YGL136C YGL136C

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