SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for YLR105C from Saccharomyces cerevisiae SGD

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YLR105C
Domain Number 1 Region: 258-336
Classification Level Classification E-value
Superfamily tRNA-intron endonuclease catalytic domain-like 2.09e-25
Family tRNA-intron endonuclease catalytic domain-like 0.0025
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
ribonuclease activity 1.939 160.98
endonuclease activity 2.013 160.98
nuclease activity 1.69 14.41
Biological Process IC (bits) H-Score
RNA processing 1.457 55.68
ncRNA processing 1.878 11.67
RNA phosphodiester bond hydrolysis 2.034 6.69
nucleic acid phosphodiester bond hydrolysis 1.72 6.11
ncRNA metabolic process 1.572 3.37

Protein sequence

External link(s) Locus: YLR105C   Protein: S000004095
Sequence length 377
Comment SEN2 SGDID:S000004095, Chr XII from 348181-347048, reverse complement, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease"
Sequence
MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKSTNALNDKVHVDFIGDT
TLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKARTEARLGLNDTPLHNRGGTKSNTET
EMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHIDEENILLEKQRESLRKFKLKQ
TEDVGIVAQQQDISESNLRDEDNNLLDENGDLLPLESLELMPVEAMFLTFALPVLDISPA
CLAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCVRSGIKFGCDYLLYKRGPPFQHAEF
CVMGLDHDVSKDYTWYSSIARVVGGAKKTFVLCYVERLISEQEAIALWKSNNFTKLFNSF
QVGEVLYKRWVPGRNRD
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Identical sequences A7A109 B3LT73 C7GQS8 C8ZD76 E7KRN4 G2WIU8 H0GK70 N1NZ86 P16658 W7PCV2 W7QVN9
YLR105C YLR105C tr|A7A109|A7A109_YEAS7 SCRT_05090 YLR105C YLR105C YLR105C YLR105C CX00052 YLR105C YLR105C YLR105C YLR105C YLR105C 4932.YLR105C YLR105C YLR105C

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