SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for YLR117C from Saccharomyces cerevisiae SGD

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YLR117C
Domain Number 1 Region: 55-545
Classification Level Classification E-value
Superfamily TPR-like 3.7e-60
Family HAT/Suf repeat 0.011
Further Details:      
 
Domain Number 2 Region: 526-644
Classification Level Classification E-value
Superfamily TPR-like 2.28e-05
Family Tetratricopeptide repeat (TPR) 0.059
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
cilium 1.61 18.82
nuclear outer membrane-endoplasmic reticulum membrane network 1.554 16.98
endoplasmic reticulum part 1.429 16.98
mitochondrial envelope 1.57 11.09
mitochondrial membrane part 1.917 11.09
nucleoplasm part 1.419 10.09
transcription factor complex 1.881 10.09
coated vesicle 1.74 9.82
cytoplasmic vesicle part 1.737 9.82
transport vesicle 2.067 9.82
Biological Process IC (bits) H-Score
mitotic cell cycle 1.528 26.73
nuclear division 1.985 26.73
cilium organization 2.112 23.87
muscle contraction 1.392 19.65
circulatory system process 1.653 19.65
cilium morphogenesis 1.418 17.29
protein folding 1.901 16.99
regulation of cellular carbohydrate metabolic process 1.946 16.11
glucose homeostasis 1.827 16.11
regulation of cellular ketone metabolic process 2.061 16.11

Protein sequence

External link(s) Locus: YLR117C   Protein: S000004107
Sequence length 687
Comment CLF1 SGDID:S000004107, Chr XII from 384535-382472, reverse complement, Verified ORF, "Essential splicesome assembly factor; contains multiple tetratricopeptide repeat (TPR) protein-binding motifs and interacts specifically with many spliceosome components, may serve as a scaffold during splicesome assembly"
Sequence
MDTLEPTAVDTHVSAEQILRDVYKKGQKARGSTNIDILDLEELREYQRRKRTEYEGYLKR
NRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYIDAELKVKCINHARN
LMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSLEPGVNAWNSFVDFEIRQK
NWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTVANLQNLQIWSD
MEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPSNQLLKAGLLDFEKQFGDINSIEET
ISYKRKMEYETILSNNAYDYDTWWLYLDLISESFPKQIMQTFEKAIVDSRPKELSKNVQW
KRYIYLWMRYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKFLIRHDDV
PKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGEL
EENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARKLYRRYLEL
NQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLEARKVFEEAIV
FFKEKDDKQGRLSILEALKDYEETYGTELDQETVKKRFPKVIKKVRLQNGVEEEFVDYIF
PDDIDDDKPKPSKFLELAKKWKQEQAL
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Identical sequences N1NY82 Q12309
YLR117C 4932.YLR117C YLR117C YLR117C YLR117c___KOG1915 355002 YR291 YLR117C

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