SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for YML008C from Saccharomyces cerevisiae SGD

Domain architecture


Domain assignment details

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Strong hits

Sequence:  YML008C
Domain Number 1 Region: 72-298,329-370
Classification Level Classification E-value
Superfamily S-adenosyl-L-methionine-dependent methyltransferases 2.53e-56
Family CAC2371-like 0.038
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
protein methylation 2.061 71.79
RNA modification 2.179 57.12
mRNA metabolic process 1.622 33.93
ncRNA metabolic process 1.572 27.74
RNA processing 1.457 24.7
regulation of gene silencing 2.227 21.93
DNA modification 1.931 20.52
sulfur compound metabolic process 1.457 19.59
coenzyme metabolic process 1.622 19.59
mitochondrion organization 1.548 19.49
Cellular Component IC (bits) H-Score
transferase complex 1.423 15.57
methyltransferase complex 2.218 10.08
transcription factor complex 1.912 8.54
organelle inner membrane 1.669 7.47
mitochondrial envelope 1.573 7.47
mitochondrial membrane part 1.917 7.47
trans-Golgi network 1.793 6.98
nucleolus 1.641 6.45
chromosomal part 1.477 5.56
chromatin 1.822 5.56

Protein sequence

External link(s) Locus: YML008C   Protein: S000004467
Sequence length 383
Comment ERG6 SGDID:S000004467, Chr XIII from 252990-251839, reverse complement, Verified ORF, "Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to both lipid particles and mitochondrial outer membrane"
Sequence
MSETELRKRQAQFTRELHGDDIGKKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEE
RRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRG
DLVLDVGCGVGGPAREIARFTGCNVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMK
MDFEENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRK
IAYEIELGDGIPKMFHVDVARKALKNCGFEVLVSEDLADNDDEIPWYYPLTGEWKYVQNL
ANLATFFRTSYLGRQFTTAMVTVMEKLGLAPEGSKEVTAALENAAVGLVAGGKSKLFTPM
MLFVARKPENAETPSQTSQEATQ
Download sequence
Identical sequences A6ZM54 C7GLC6 G2WK44 N1P5A5 P25087
YML008C 4932.YML008C YML008C YML008C tr|A6ZM54|A6ZM54_YEAS7 YML008C YML008C 355019 NYSGXRC-6385a YR305 YML008C YML008C YML008C YML008C YML008C YML008C YML008C YML008C

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