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Domain assignment for YML124C from Saccharomyces cerevisiae SGD

Domain architecture

Domain assignment details

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Strong hits

Sequence:  YML124C
Domain Number 1 Region: 1-245
Classification Level Classification E-value
Superfamily Tubulin nucleotide-binding domain-like 5.1e-94
Family Tubulin, GTPase domain 0.00000000599
Further Details:      
Domain Number 2 Region: 247-440
Classification Level Classification E-value
Superfamily Tubulin C-terminal domain-like 8.55e-81
Family Tubulin, C-terminal domain 0.0000000369
Further Details:      

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
structural constituent of cytoskeleton 1.858 67.11
GTPase activity 2.091 11.96
purine ribonucleoside binding 1.996 11.83
guanyl nucleotide binding 1.996 11.09
Biological Process IC (bits) H-Score
microtubule-based process 1.532 35.74
unidimensional cell growth 2.183 35.61
cell growth 1.652 26.55
fruit development 2.084 25.84
female gamete generation 1.501 25.5
nuclear division 1.865 25.5
meiotic cell cycle process 1.982 25.5
single-organism intracellular transport 1.406 23.97
microtubule-based movement 1.993 23.97
protein polymerization 2.15 21.55
Cellular Component IC (bits) H-Score
microtubule 1.891 65.26
polymeric cytoskeletal fiber 1.688 48.29
spindle 1.815 8.18
microtubule cytoskeleton 1.44 6.82
outer membrane 2.091 6.27
organelle envelope 1.405 5.68
plastid 1.525 5.55
chloroplast stroma 2.009 5.55
thylakoid 2.192 5.55

Protein sequence

External link(s) Locus: YML124C   Protein: S000004593
Sequence length 445
Comment TUB3 SGDID:S000004593, Chr XIII from 23684-23660,23361-22049, reverse complement, Verified ORF, "Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p"
Download sequence
Identical sequences A6ZLU1 B3LLD6 C8ZE78 N1NZC7 P09734
YML124C YML124C YML124C YML124C YML124C YML124C 4932.YML124C YML124C YML124C YML124C SCRT_01776 YML124C YML124C YML124C YML124C YML124C tr|A6ZLU1|A6ZLU1_YEAS7 YML124C YML124C YML124C

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