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Domain assignment for O94810 from Uniprot 2017_06 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  O94810
Domain Number 1 Region: 290-419
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 2.49e-43
Family Regulator of G-protein signaling, RGS 0.00000293
Further Details:      
 
Domain Number 2 Region: 13-114
Classification Level Classification E-value
Superfamily "Winged helix" DNA-binding domain 1.9e-29
Family DEP domain 0.0039
Further Details:      
 
Domain Number 3 Region: 216-278
Classification Level Classification E-value
Superfamily Transducin (heterotrimeric G protein), gamma chain 2.09e-17
Family Transducin (heterotrimeric G protein), gamma chain 0.0042
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
protein-DNA complex 1.923 57.09
cytoplasmic side of membrane 1.952 34.16
cytoplasmic vesicle part 1.417 32.5
endosome 1.351 32.5
endosome membrane 1.934 32.5
actin cytoskeleton 1.374 30.29
chromosomal part 1.512 14.52
transferase complex 1.369 13.95
nucleoplasm part 1.369 13.95
extrinsic component of plasma membrane 2.107 12.91

Protein sequence

External link(s) O94810
Sequence length 467
Comment (sp|O94810|RGS11_HUMAN) Regulator of G-protein signaling 11 KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=RGS11; OC=Catarrhini; Hominidae; Homo.
Sequence
MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGSDVVQW
LAQKFCVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTSTLRPAAE
LDYAIYLAKKNIRKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRL
VIACQEQTYWLVNRPPPGAPDVLEQGPGRGSCAASRVLMTKSADFHKREIEYFRKALGRT
RVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRVERW
GFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVDAVYEQFLA
PGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLMKKDSYPRFLKSDMYKALLAE
AGIPLEMKRRVFPFTWRPRHSSPSPALLPTPVEPTAACGPGGGDGVA
Download sequence
Identical sequences O94810 Q4TT70
ENSP00000380876 ENSP00000168869 gi|34452688|ref|NP_899180.1| 9606.ENSP00000380876 ENSP00000380876

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