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Domain assignment for P41159 from Uniprot 2017_06 genome

Domain architecture

Domain assignment details

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Strong hits

Sequence:  P41159
Domain Number 1 Region: 24-167
Classification Level Classification E-value
Superfamily 4-helical cytokines 3.71e-60
Family Long-chain cytokines 0.000000159
Further Details:      

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
extracellular space 1.299 56.02
endosome 1.35 13.65
cytoplasmic vesicle part 1.416 13.65
filopodium 1.855 9.86
actin-based cell projection 1.621 6.95
cell leading edge 1.424 4.36
Molecular Function IC (bits) H-Score
cytokine receptor binding 1.958 73.78
receptor regulator activity 1.503 45.41
cytokine binding 1.936 40.05
enzyme activator activity 1.415 16.66
cysteine-type peptidase activity 2.038 12.97
endopeptidase activity 1.555 9.09
growth factor receptor binding 2.172 4.33
hormone activity 1.784 4.3

Protein sequence

External link(s) P41159
Sequence length 167
Comment (sp|P41159|LEP_HUMAN) Obesity factor KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=OB OC=Catarrhini; Hominidae; Homo.
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Identical sequences A4D0Y8 P41159
gi|4557715|ref|NP_000221.1| 9606.ENSP00000312652 NP_000221.1.87134 NP_000221.1.92137 ENSP00000312652 ENSP00000312652 ENSP00000312652

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