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Domain assignment for P41159 from Uniprot 2017_06 genome

Domain architecture

Domain assignment details

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Strong hits

Sequence:  P41159
Domain Number 1 Region: 24-167
Classification Level Classification E-value
Superfamily 4-helical cytokines 3.71e-60
Family Long-chain cytokines 0.000000159
Further Details:      

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
cytokine receptor binding 1.974 73.79
cytokine binding 1.952 40.06
enzyme activator activity 1.431 16.66
cysteine-type peptidase activity 2.054 12.98
endopeptidase activity 1.571 9.1
growth factor receptor binding 2.188 4.33
hormone activity 1.767 4.3
Cellular Component IC (bits) H-Score
extracellular space 1.3 56.04
cytoplasmic vesicle part 1.417 13.65
endosome 1.351 13.65
filopodium 1.861 9.86
actin-based cell projection 1.622 6.95
cell leading edge 1.426 4.36

Protein sequence

External link(s) P41159
Sequence length 167
Comment (sp|P41159|LEP_HUMAN) Obesity factor KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=OB OC=Catarrhini; Hominidae; Homo.
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Identical sequences A4D0Y8 P41159
ENSP00000312652 9606.ENSP00000312652 ENSP00000312652 gi|4557715|ref|NP_000221.1| ENSP00000312652

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