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Domain assignment for ENSPTRP00000060270 from Pan troglodytes 76_2.1.4

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSPTRP00000060270
Domain Number 1 Region: 321-517
Classification Level Classification E-value
Superfamily Hemopexin-like domain 5.36e-69
Family Hemopexin-like domain 0.00000746
Further Details:      
 
Domain Number 2 Region: 109-275
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 9.07e-57
Family Matrix metalloproteases, catalytic domain 0.000000114
Further Details:      
 
Domain Number 3 Region: 18-92
Classification Level Classification E-value
Superfamily PGBD-like 1.07e-19
Family MMP N-terminal domain 0.0036
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 2.041 167.45
endopeptidase activity 1.576 149.51
zinc ion binding 1.567 42.55
growth factor receptor binding 2.175 16
cytokine receptor binding 1.96 16
enzyme activator activity 1.426 14.68
integrin binding 1.558 12.31
fibronectin binding 2.151 10.88
serine hydrolase activity 1.585 10.2
peptide transporter activity 1.652 9.95
Cellular Component IC (bits) H-Score
Golgi lumen 2.204 18.78
brush border 1.374 15.66
neuron projection terminus 2.128 10.01
exocytic vesicle 1.966 9.77
Golgi membrane 1.599 9.32
trans-Golgi network 1.734 9.32
vacuolar part 1.526 6.31
host intracellular part 1.994 5.4
dendrite 1.581 5.09
lysosomal membrane 1.908 5.02

Protein sequence

External link(s) Protein: ENSPTRP00000060270   Gene: ENSPTRG00000013434   Transcript: ENSPTRT00000074314
Sequence length 593
Comment pep:known_by_projection chromosome:CHIMP2.1.4:20:32052239:32103884:1 gene:ENSPTRG00000013434 transcript:ENSPTRT00000074314 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPRSRGGRAAPGPPLAVARADEAEAPFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVS
TMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSI
HNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDS
SPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEH
SSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSE
RKHERQPRPPRPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQE
GYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLP
REGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKE
GYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVDIMVT
INDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
Download sequence
Identical sequences H2RFH7
ENSPTRP00000060270

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