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Domain assignment for ENSPTRP00000060270 from Pan troglodytes 76_2.1.4

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSPTRP00000060270
Domain Number 1 Region: 321-517
Classification Level Classification E-value
Superfamily Hemopexin-like domain 5.36e-69
Family Hemopexin-like domain 0.00000746
Further Details:      
 
Domain Number 2 Region: 109-275
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 9.07e-57
Family Matrix metalloproteases, catalytic domain 0.000000114
Further Details:      
 
Domain Number 3 Region: 18-92
Classification Level Classification E-value
Superfamily PGBD-like 1.07e-19
Family MMP N-terminal domain 0.0036
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.48 22.54
Golgi lumen 2.239 12.24
secretory granule 1.826 10.6
neuron projection terminus 2.106 10.52
lysosomal membrane 1.998 8.25
trans-Golgi network 1.797 7.99
coated vesicle 1.74 7.78
clathrin-coated vesicle 1.876 7.78
lytic vacuole 1.57 7.42
vacuolar part 1.621 7.11
Molecular Function IC (bits) H-Score
metallopeptidase activity 1.957 173.75
endopeptidase activity 1.54 149.12
zinc ion binding 1.659 43.58
integrin binding 1.753 17.75
cytokine receptor binding 2.035 15.08
growth factor receptor binding 1.997 15.08
enzyme activator activity 1.401 14.47
amide binding 1.711 13.09
collagen binding 1.838 10.43
protein complex binding 1.491 8.07

Protein sequence

External link(s) Protein: ENSPTRP00000060270   Gene: ENSPTRG00000013434   Transcript: ENSPTRT00000074314
Sequence length 593
Comment pep:known_by_projection chromosome:CHIMP2.1.4:20:32052239:32103884:1 gene:ENSPTRG00000013434 transcript:ENSPTRT00000074314 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPRSRGGRAAPGPPLAVARADEAEAPFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVS
TMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSI
HNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDS
SPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEH
SSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSE
RKHERQPRPPRPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQE
GYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLP
REGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKE
GYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVDIMVT
INDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
Download sequence
Identical sequences H2RFH7
ENSPTRP00000060270

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