SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): reproduction

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ 1:   biological_process [GO:0008150] <24>
0:   reproduction [GO:0000003] <6>(37|41) (304|189|85)
- 1:   reproductive process [GO:0022414] <78>(33|37) (289|181|83)
- 1:   asexual reproduction [GO:0019954] <7>(0|1) (14|4|1)
- 1:   sexual reproduction [GO:0019953] <6>(13|15) (198|125|52)
- 1:   multicellular organism reproduction [GO:0032504] <3>(20|21) (213|135|54)
- 1:   reproduction of a single-celled organism [GO:0032505] <3>(0|0) (11|1|0)
- 1:   reproduction of symbiont in host [GO:0061887](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
14-3-3 protein0.00008220.000435Direct
AF0104/ALDC/Ptd012-like0.00044610.0006219Direct
ARM repeat0.00004280.000000001023Direct
Bcl-2 inhibitors of programmed cell death0.00000010170.0000009233Direct
BPTI-like0.00000012910.00000005446Direct
Cadherin-like0.0000000013360.0004866Direct
Cu,Zn superoxide dismutase-like0.000000000000031880.00000001546Direct
Cystine-knot cytokines0.000000099590.000000000007793Direct
Defensin-like0.0000000015370.0001682Direct
DNA topoisomerase IV, alpha subunit0.000024660.0000000001239Direct
Fertilization protein00Direct
Homeodomain-like0.00023510Direct
Inhibitor of apoptosis (IAP) repeat0.00017830.0000002304Direct
Insect pheromone/odorant-binding proteins0.000000063860.0006328Direct
P-loop containing nucleoside triphosphate hydrolases0.00017290.0000001401Direct
PEBP-like0.0000000029890.0002777Direct
PHP14-like00.00000000000002102Direct
Profilin (actin-binding protein)0.00000014690.00003752Direct
Protein kinase-like (PK-like)0.0000000000011830Direct
Serpins0.0000000000000016250.000000000285Direct
Tubulin C-terminal domain-like0.0000068650.00000000000002102Direct
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.0000028570.02761Inherited
Annexin0.00045520.1583Inherited
NagB/RpiA/CoA transferase-like0.019940.1292Inherited
Plant invertase/pectin methylesterase inhibitor0.00019630.002224Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.038950.4927Inherited
Trypsin-like serine proteases0.000000034010.001961Inherited
Casein kinase II beta subunit0.00017830.002535Inherited
NAD(P)-binding Rossmann-fold domains11Inherited
WD40 repeat-like0.00050210.005395Inherited
4-helical cytokines0.0010310.00001657Inherited
Heme-dependent peroxidases0.0013710.001349Inherited
Lysozyme-like0.0052840.2879Inherited
Terpenoid synthases0.10650.9167Inherited
Metalloproteases ("zincins"), catalytic domain0.30670.0000000249Inherited
Phospholipase D/nuclease0.00000000012510.2414Inherited
Histone-fold0.013090.142Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
14-3-3 protein0.00020170.0007701Direct
AF0104-like0.0000073680.00004301Direct
Bcl-2 inhibitors of programmed cell death0.00000067110.000002838Direct
Cu,Zn superoxide dismutase-like0.00000000000039410.00000004992Direct
Defensin0.0000000000000022720.0000001417Direct
DNA topoisomerase IV, alpha subunit0.000038820.0000000002441Direct
Eukaryotic proteases0.00000017370.00006035Direct
Fertilization protein00Direct
Gonadodropin/Follitropin0.000000013580.00001768Direct
Homeodomain0.00027710.0000000003421Direct
Inhibitor of apoptosis (IAP) repeat0.0003660.0000006364Direct
Insect pheromone/odorant-binding proteins0.00000020780.0003471Direct
Janus/Ocnus00Direct
Long-chain cytokines0.000000018050.00000000004366Direct
Nuclease0.000000000023930.000000007348Direct
Phosphatidylethanolamine binding protein0.000000000040080.000008443Direct
Plant lipid-transfer and hydrophobic proteins0.000000054650.0000836Direct
Profilin (actin-binding protein)0.0000005380.00006289Direct
Protein kinases, catalytic subunit0.000000000000072650Direct
Pumilio repeat0.000021650.0001858Direct
Serpins0.000000000000069710.000000001927Direct
Small Kunitz-type inhibitors & BPTI-like toxins0.000028070.00001419Direct
Tubulin, C-terminal domain0.0000098310.0000000000001881Direct
Annexin0.0011570.2024Inherited
Armadillo repeat0.0000091850.0107Inherited
CCP-like0.0020620.05415Inherited
Plastocyanin/azurin-like0.00012820.0261Inherited
Germin/Seed storage 7S protein0.0049450.005198Inherited
Nucleosome core histones0.15840.3337Inherited
IF2B-like0.0010430.0002375Inherited
AlkB-like0.000094780.006112Inherited
Casein kinase II beta subunit0.0003660.003454Inherited
Tyrosine-dependent oxidoreductases11Inherited
WD40-repeat0.0034070.07663Inherited
C-type lysozyme0.00011850.001115Inherited
Carboxylesterase0.039570.3901Inherited
Isoprenyl diphosphate synthases0.041740.1132Inherited
Astacin0.0021280.02925Inherited
RecA protein-like (ATPase-domain)0.0068850.00005833Inherited
G proteins0.000000026541Inherited
Papain-like0.00027840.06085Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Protein kinase-like (PK-like)0Direct
Tudor/PWWP/MBT0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
SpoVG-like0Direct
Pseudo ankyrin repeat-like0Direct
Fertilization protein0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
PAZ domain0Direct
Chromo domain-like0Direct
Homeodomain-like0Direct
DNA repair protein MutS, domain III0.000000000000006464Direct
SRF-like0.000000000000006464Direct
PHP14-like0.00000000000001092Direct
Tubulin C-terminal domain-like0.00000000000001092Direct
The spindle assembly checkpoint protein mad20.0000000000000127Direct
HMG-box0.0000000000000284Direct
Cyclin-like0.0000000000003105Direct
dsRNA-binding domain-like0.000000000002133Direct
Cystine-knot cytokines0.000000000004367Direct
DNA-binding pseudobarrel domain0.000000000005118Direct
Nuclear receptor ligand-binding domain0.00000000000719Direct
ABC transporter transmembrane region0.0000000000133Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.00000000002658Direct
Rad51 N-terminal domain-like0.00000000003337Direct
Tubulin nucleotide-binding domain-like0.00000000003847Direct
L domain-like0.00000000006836Direct
DNA topoisomerase IV, alpha subunit0.00000000007112Direct
Serpins0.0000000001646Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0000000003821Direct
ARM repeat0.0000000006007Direct
BRK domain-like0.0000000009883Direct
Blood coagulation inhibitor (disintegrin)0.000000001557Direct
Polo-box domain0.000000004148Direct
Cu,Zn superoxide dismutase-like0.000000009406Direct
FAS1 domain0.00000001026Direct
Metalloproteases ("zincins"), catalytic domain0.00000001524Direct
RNA-binding domain, RBD0.0000000165Direct
PR-1-like0.0000000196Direct
DNA mismatch repair protein MutL0.00000002567Direct
BPTI-like0.00000003362Direct
HLH, helix-loop-helix DNA-binding domain0.00000003891Direct
ACT-like0.00000007962Direct
P-loop containing nucleoside triphosphate hydrolases0.00000008733Direct
STAT0.0000001016Direct
Bromodomain0.0000001422Direct
SMAD MH1 domain0.0000001438Direct
p53-like transcription factors0.0000001439Direct
Inhibitor of apoptosis (IAP) repeat0.0000001444Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.000000182Direct
Crisp domain-like0.000000291Direct
FYVE/PHD zinc finger0.0000004589Direct
SMAD/FHA domain0.0000005681Direct
Bcl-2 inhibitors of programmed cell death0.0000005898Direct
Cullin repeat-like0.0000006446Direct
HR1 repeat0.0000007075Direct
A heparin-binding domain0.0000008984Direct
Smc hinge domain0.000001847Direct
Transcription factor STAT-4 N-domain0.000002425Direct
BRCA2 helical domain0.000002595Direct
BRCA2 tower domain0.000002595Direct
Spectrin repeat0.000002833Direct
ARID-like0.000002862Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.000003432Direct
Insulin-like0.000005973Direct
Cullin homology domain0.00001026Direct
4-helical cytokines0.00001103Direct
TAZ domain0.00001208Direct
SAM/Pointed domain0.00002254Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.00002375Direct
Profilin (actin-binding protein)0.00002526Direct
NAC domain0.00003239Direct
MAST3 pre-PK domain-like0.0000421Direct
Dimerization cofactor of HNF-1 alpha0.00004482Direct
PYP-like sensor domain (PAS domain)0.00005105Direct
Stathmin0.00007001Direct
SBT domain0.00008712Direct
Defensin-like0.0001159Direct
POZ domain0.0001255Direct
YWTD domain0.0001309Direct
Kix domain of CBP (creb binding protein)0.0001312Direct
DNA repair protein MutS, domain II0.0001374Direct
Nuclear receptor coactivator interlocking domain0.0001871Direct
Myosin S1 fragment, N-terminal domain0.0001871Direct
PEBP-like0.0001933Direct
G protein-binding domain0.0002634Direct
beta-beta-alpha zinc fingers0.0002714Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.0002717Direct
Regulator of G-protein signaling, RGS0.0002963Direct
14-3-3 protein0.000305Direct
Cadherin-like0.0003416Direct
SH2 domain0.0004114Direct
Integrin domains0.0004198Direct
AF0104/ALDC/Ptd012-like0.0004387Direct
Insect pheromone/odorant-binding proteins0.0004465Direct
Phenylalanine zipper0.0006164Direct
BAR/IMD domain-like0.0006768Direct
Formin homology 2 domain (FH2 domain)0.0007779Direct
DNA repair protein MutS, domain I0.0008917Direct
Heme-dependent peroxidases0.0009653Direct
HRDC-like0.6211Inherited
Nucleotide-diphospho-sugar transferases0.1459Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.2353Inherited
Translation proteins1Inherited
Cupredoxins1Inherited
Glutamine synthetase, N-terminal domain0.06632Inherited
Annexin0.1273Inherited
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.02108Inherited
PHL pollen allergen0.03884Inherited
Barwin-like endoglucanases0.4431Inherited
Glutamine synthetase/guanido kinase0.658Inherited
Aquaporin-like0.4378Inherited
Arabinanase/levansucrase/invertase0.7855Inherited
Thiolase-like0.9096Inherited
Immunoglobulin0.1396Inherited
Complement control module/SCR domain0.9911Inherited
Family A G protein-coupled receptor-like1Inherited
E set domains0.742Inherited
Prokaryotic type I DNA topoisomerase0.0103Inherited
Sec63 N-terminal domain-like0.002011Inherited
Restriction endonuclease-like0.001347Inherited
RuvA domain 2-like0.002228Inherited
Ras GEF0.5936Inherited
Pectin lyase-like0.5452Inherited
YhbY-like0.07924Inherited
alpha/beta-Hydrolases1Inherited
Succinyl-CoA synthetase domains0.4927Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
Oxysterol-binding protein-like0.1914Inherited
UBC-like0.5998Inherited
Nucleoside diphosphate kinase, NDK0.7448Inherited
SpoIIaa-like0.1194Inherited
Phospholipase A2, PLA20.02618Inherited
Rhomboid-like0.6092Inherited
eIF4e-like0.7297Inherited
RNI-like1Inherited
Bet v1-like0.1761Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
WD40 repeat-like0.003968Inherited
EGF/Laminin0.007886Inherited
Activating enzymes of the ubiquitin-like proteins0.09283Inherited
Ubiquitin-like0.3855Inherited
E2F-DP heterodimerization region0.02182Inherited
Rap/Ran-GAP0.2275Inherited
Class II aaRS and biotin synthetases1Inherited
Leucine zipper domain0.006118Inherited
SET domain0.05437Inherited
Multidrug resistance efflux transporter EmrE1Inherited
F-box domain1Inherited
DNase I-like0.9323Inherited
Voltage-gated potassium channels1Inherited
Cysteine proteinases0.9914Inherited
Multidrug efflux transporter AcrB transmembrane domain0.02594Inherited
C-type lectin-like0.9134Inherited
Caspase-like0.2404Inherited
CAD & PB1 domains0.001077Inherited
NagB/RpiA/CoA transferase-like0.1033Inherited
Glycoside hydrolase/deacetylase0.3778Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
(Trans)glycosidases1Inherited
PX domain0.9186Inherited
HIT/MYND zinc finger-like0.07605Inherited
FKBP-like0.528Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Putative DNA-binding domain0.02936Inherited
DEATH domain1Inherited
Sema domain0.5676Inherited
Plexin repeat0.1182Inherited
RING/U-box0.9024Inherited
Histone-fold0.1139Inherited
Ribonuclease H-like0.01001Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Tropomyosin0.1237Inherited
ENTH/VHS domain0.6188Inherited
Casein kinase II beta subunit0.001836Inherited
PHM/PNGase F0.002074Inherited
t-snare proteins0.1128Inherited
Hedgehog/intein (Hint) domain0.007879Inherited
Hedgehog/DD-peptidase0.005274Inherited
Spermadhesin, CUB domain0.8142Inherited
Riboflavin synthase domain-like0.9619Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.979Inherited
SH3-domain0.01911Inherited
Ankyrin repeat0.1857Inherited
GTPase activation domain, GAP0.9947Inherited
Six-hairpin glycosidases1Inherited
DEK C-terminal domain0.03296Inherited
Sigma2 domain of RNA polymerase sigma factors0.2526Inherited
Sigma3 and sigma4 domains of RNA polymerase sigma factors0.4254Inherited
Cytochrome b5-like heme/steroid binding domain0.5138Inherited
Homodimeric domain of signal transducing histidine kinase0.548Inherited
CheY-like1Inherited
beta-lactamase/transpeptidase-like1Inherited
Calponin-homology domain, CH-domain0.01999Inherited
(Phosphotyrosine protein) phosphatases II0.1837Inherited
Colipase-like0.004023Inherited
Zn-dependent exopeptidases1Inherited
PK C-terminal domain-like0.3785Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
RmlC-like cupins1Inherited
PK beta-barrel domain-like0.922Inherited
Clavaminate synthase-like0.6827Inherited
RNase III domain-like0.01436Inherited
PABC (PABP) domain0.04302Inherited
Plant invertase/pectin methylesterase inhibitor0.001606Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.8496Inherited
cAMP-binding domain-like0.379Inherited
DNA-binding domain0.002819Inherited
WRKY DNA-binding domain0.05819Inherited
Nucleotidylyl transferase0.9329Inherited
ValRS/IleRS/LeuRS editing domain0.334Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.7895Inherited
TPR-like1Inherited
Calpain large subunit, middle domain (domain III)0.03338Inherited
Trypsin-like serine proteases0.001414Inherited
Nucleoplasmin-like core domain0.005806Inherited
GroEL apical domain-like0.07106Inherited
Lysozyme-like0.2379Inherited
Trefoil0.06148Inherited
GroEL-intermediate domain like0.08897Inherited
GroEL equatorial domain-like0.1156Inherited
Cystatin/monellin0.5347Inherited
Protease propeptides/inhibitors0.3918Inherited
Subtilisin-like0.112Inherited
PGBD-like0.07957Inherited
Hemopexin-like domain0.09502Inherited
Trimeric LpxA-like enzymes0.153Inherited
Toll/Interleukin receptor TIR domain0.5684Inherited
A DNA-binding domain in eukaryotic transcription factors0.1136Inherited
Terpenoid synthases0.8184Inherited
UBA-like0.898Inherited
Ran binding protein zinc finger-like1Inherited
HD-domain/PDEase-like1Inherited
Fibrinogen C-terminal domain-like0.7363Inherited
Integrin beta tail domain0.03853Inherited
Kringle-like0.1474Inherited
Growth factor receptor domain0.7095Inherited
vWA-like1Inherited
Alpha-macroglobulin receptor domain0.002664Inherited
Frizzled cysteine-rich domain0.02163Inherited
Cytochrome P4500.9475Inherited
SRCR-like1Inherited
MHC antigen-recognition domain1Inherited
Cytokine0.4443Inherited
PLC-like phosphodiesterases0.0188Inherited
C-terminal domain of PLC-beta0.7135Inherited
EF-hand1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.001356Inherited
PH domain-like0.03607Inherited
Phospholipase D/nuclease0.1978Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.00655Inherited
C-terminal domain of adenylylcyclase associated protein0.03395Inherited
GAS2 domain-like0.2836Inherited
Cysteine-rich domain0.03266Inherited
SAICAR synthase-like0.06837Inherited
KA1-like0.02046Inherited
Snake toxin-like0.001786Inherited
Kazal-type serine protease inhibitors0.2406Inherited
N-terminal domain of cbl (N-cbl)0.001466Inherited
Second domain of FERM0.7283Inherited
L27 domain0.05837Inherited
alpha-catenin/vinculin-like0.186Inherited
I/LWEQ domain0.01235Inherited
Actin depolymerizing proteins0.3115Inherited
CRAL/TRIO domain0.03048Inherited
SOCS box-like0.557Inherited
A middle domain of Talin 10.00388Inherited
PDZ domain-like0.02624Inherited
beta-sandwich domain of Sec23/240.1034Inherited
Tetraspanin0.002037Inherited
SAP domain0.2309Inherited
Ypt/Rab-GAP domain of gyp1p0.4669Inherited
Chaperone J-domain0.8254Inherited
NAP-like0.1265Inherited
Staphylococcal nuclease0.1583Inherited
Eukaryotic type KH-domain (KH-domain type I)0.03024Inherited
Fibronectin type III0.1239Inherited
Nucleotide cyclase0.7751Inherited
Subunits of heterodimeric actin filament capping protein Capz0.03884Inherited
NAD kinase/diacylglycerol kinase-like0.8786Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.4186Inherited
TSP-1 type 1 repeat0.722Inherited
DBL homology domain (DH-domain)0.03333Inherited
BRCT domain0.002119Inherited
Lamin A/C globular tail domain0.0303Inherited
Ribosomal protein S5 domain 2-like1Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.2392Inherited
Metallo-dependent phosphatases0.8109Inherited
DNA/RNA polymerases1Inherited
Mago nashi protein0.005814Inherited
"Winged helix" DNA-binding domain0.1096Inherited
Orange domain-like0.1514Inherited
SPOC domain-like0.008764Inherited
lambda repressor-like DNA-binding domains1Inherited
Galactose-binding domain-like0.2364Inherited
Kelch motif0.8315Inherited
Integrin alpha N-terminal domain0.09489Inherited
HAD-like1Inherited
Transducin (alpha subunit), insertion domain0.9667Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.5863Inherited
Calcium ATPase, transduction domain A0.7992Inherited
Acid proteases0.8505Inherited
Calcium ATPase, transmembrane domain M0.8938Inherited
Nucleic acid-binding proteins0.007821Inherited
DNA polymerase beta, N-terminal domain-like0.1289Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    49899,54001
  • 49899 - Concanavalin A-like lectins/glucanases
  • 54001 - Cysteine proteinases
  • 0Direct
    47769,140860
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    47473,88713
  • 47473 - EF-hand
  • 88713 - Glycoside hydrolase/deacetylase
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000000003737Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0000000000004039Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0000000000004815Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.000000000001544Direct
    47794,52540
  • 47794 - Rad51 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000001842Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000004873Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.0000000001762Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0000000002639Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000000001813Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.000000005728Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.000000006921Direct
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.00000001177Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000005315Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000005315Direct
    55797,57546
  • 55797 - PR-1-like
  • 57546 - Crisp domain-like
  • 0.00000006872Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.00000007704Direct
    48403,140860
  • 48403 - Ankyrin repeat
  • 140860 - Pseudo ankyrin repeat-like
  • 0.00000009098Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.000000182Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0000002585Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00000038Direct
    81296,48239
  • 81296 - E set domains
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 0.0000004562Direct
    55961,55961
  • 55961 - Bet v1-like
  • 55961 - Bet v1-like
  • 0.0000004675Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.0000004679Direct
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.0000006078Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.000002001Direct
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.000002595Direct
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000002595Direct
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000002595Direct
    48371,49785
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0.000002671Direct
    63748,48371
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 0.000003345Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.000003345Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0.000004495Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00000502Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000009762Direct
    46785,48097
  • 46785 - "Winged helix" DNA-binding domain
  • 48097 - Regulator of G-protein signaling, RGS
  • 0.00001193Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.00001285Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000137Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00001638Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00001847Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000222Direct
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.00002375Direct
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00002375Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.00002773Direct
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00002892Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0.0000371Direct
    101936,101936
  • 101936 - DNA-binding pseudobarrel domain
  • 101936 - DNA-binding pseudobarrel domain
  • 0.0000521Direct
    53150,48334
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0.00005587Direct
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.0000766Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.00008634Direct
    51161,48371
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.0001001Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001431Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.0001459Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.0001589Direct
    55486,48726
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48726 - Immunoglobulin
  • 0.0001589Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.0001589Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0001701Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.0001871Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.0001871Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0002477Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0002559Direct
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0.0002598Direct
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002717Direct
    63501,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 0.0002974Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0003083Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0003202Direct
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.0003726Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.0004165Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.000457Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.0005242Direct
    49562,50729
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 50729 - PH domain-like
  • 0.0005468Direct
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.0006548Direct
    53335,53335
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.0007735Direct
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.0007775Direct
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.0009121Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.0009121Direct
    46565,48371
  • 46565 - Chaperone J-domain
  • 48371 - ARM repeat
  • 0.0009121Direct
    49899,55486
  • 49899 - Concanavalin A-like lectins/glucanases
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0009683Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0009719Direct
    54171,54171
  • 54171 - DNA-binding domain
  • 54171 - DNA-binding domain
  • 0.001447Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.03283Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.2271Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.9895Inherited
    54368,55931
  • 54368 - Glutamine synthetase, N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0.06632Inherited
    50685,49590
  • 50685 - Barwin-like endoglucanases
  • 49590 - PHL pollen allergen
  • 0.03884Inherited
    75005,49899
  • 75005 - Arabinanase/levansucrase/invertase
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1901Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.3712Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.7804Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0487Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0984Inherited
    51101,51101
  • 51101 - Mannose-binding lectins
  • 51101 - Mannose-binding lectins
  • 0.008456Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.3375Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.0134Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.1604Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.004676Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.01206Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.02182Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.08517Inherited
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0.007169Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.2721Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.6162Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.1289Inherited
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.01263Inherited
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0.002074Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.1355Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.004459Inherited
    88946,88659
  • 88946 - Sigma2 domain of RNA polymerase sigma factors
  • 88659 - Sigma3 and sigma4 domains of RNA polymerase sigma factors
  • 0.3912Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.0542Inherited
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.514Inherited
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0.005665Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.02165Inherited
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.002415Inherited
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.01412Inherited
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.004023Inherited
    57190,57190
  • 57190 - Colipase-like
  • 57190 - Colipase-like
  • 0.00292Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.03567Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.2176Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.5938Inherited
    50800,51621
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0.3095Inherited
    51621,52935
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.3325Inherited
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.002231Inherited
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.334Inherited
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.01211Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.08427Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.1316Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.1381Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.4524Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.02667Inherited
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.03853Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.3045Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.01487Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.07581Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.08414Inherited
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.00288Inherited
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.03915Inherited
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.3813Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.2028Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.001573Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.9048Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.5729Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.1714Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.004561Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.1675Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.1049Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.002385Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01198Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.05404Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.001447Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.001447Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.002074Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.1442Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.03915Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.5129Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.2055Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.3023Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.7072Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.00388Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.005097Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.6593Inherited
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0.01529Inherited
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.09936Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.1858Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 1Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.04988Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.003669Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.008623Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.124Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.07261Inherited
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0.01538Inherited
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.01827Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.01538Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.002554Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.6596Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.1432Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.00446Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.05303Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.003348Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.01491Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.2844Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.9667Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.641Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.7234Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49899,54001,49758
  • 49899 - Concanavalin A-like lectins/glucanases
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    48403,47769,140860
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    63748,48371,49785
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0Direct
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.0000000134Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0000000268Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.000001348Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000002506Direct
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000002595Direct
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.000002595Direct
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.000002595Direct
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.000002671Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00000284Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.000003345Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.000003345Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.000003479Direct
    57850,57850,57933
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.00001193Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00001367Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00001638Direct
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00002375Direct
    82153,82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.00003628Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.0000371Direct
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0000421Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0000461Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00005084Direct
    53150,48334,52540
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00005587Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0001001Direct
    53448,51161,48371
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.0001001Direct
    101936,101936,101936
  • 101936 - DNA-binding pseudobarrel domain
  • 101936 - DNA-binding pseudobarrel domain
  • 101936 - DNA-binding pseudobarrel domain
  • 0.0001399Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.000151Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.0001871Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0002477Direct
    63501,57424,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0002974Direct
    57424,57424,56487
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.0002974Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.0005242Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0005468Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000881Direct
    52047,52058,56112
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0008822Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.2109Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.04446Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.02143Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.06529Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.2648Inherited
    47370,47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.005814Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.056Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.001608Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.001279Inherited
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0238Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.05021Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.001369Inherited
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.002415Inherited
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.01412Inherited
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.004023Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.5596Inherited
    50800,51621,52935
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.3095Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2269Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.1254Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.4035Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.7148Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.1709Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.02385Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.4592Inherited
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.00288Inherited
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00288Inherited
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.03915Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.1241Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.1822Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.2353Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.4196Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.2493Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.2001Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.001447Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.001447Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.03915Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00388Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.01529Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.02788Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.006146Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03346Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04974Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.04974Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.01491Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.583Inherited


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