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Biological Process (BP): protein complex assembly

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + + 4:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ + + 3:   cellular component organization [GO:0016043] <33>(113|104) (617|594|349)
+ + + 3:   cellular component organization or biogenesis [GO:0071840] <2>(123|122) (647|619|358)
+ + 2:   cellular component assembly [GO:0022607] <53>(66|54) (363|266|162)
+ + 2:   cellular component biogenesis [GO:0044085] <13>(77|70) (409|295|170)
+ + 2:   macromolecular complex subunit organization [GO:0043933] <10>(54|44) (305|194|109)
+ 1:   macromolecular complex assembly [GO:0065003] <8>(48|37) (260|152|81)
+ 1:   protein complex biogenesis [GO:0070271] <7>(35|24) (189|116|69)
+ 1:   protein complex subunit organization [GO:0071822] <6>(38|28) (220|142|86)
0:   protein complex assembly [GO:0006461] <47>(35|24) (188|115|69)
- 1:   cellular protein complex assembly [GO:0043623] <54>(18|10) (84|34|24)
- 1:   protein oligomerization [GO:0051259] <5>(16|13) (89|67|39)
- 1:   ripoptosome assembly [GO:0097343] <2>(0|0) (2|0|0)
- 1:   ESCRT complex assembly [GO:1904895] <1>(0|0) (0|0|0)
- 1:   death-inducing signaling complex assembly [GO:0071550] <1>(0|0) (1|0|0)
- 1:   pore complex assembly [GO:0046931] <1>(0|0) (1|0|0)
- 1:   ATG1/ULK1 kinase complex assembly [GO:1904745](0|0) (0|0|0)
- 1:   C3HC4-type RING finger domain-mediated complex assembly [GO:0071537](0|0) (0|0|0)
- 1:   COPII vesicle coating [GO:0048208](0|1) (13|5|3)
- 1:   DNA recombinase mediator complex assembly [GO:1903871](0|0) (0|0|0)
- 1:   FACT complex assembly [GO:1905635](0|0) (0|0|0)
- 1:   FHA domain-mediated complex assembly [GO:0071530](0|0) (0|0|0)
- 1:   LRR domain-mediated complex assembly [GO:0071571](0|0) (0|0|0)
- 1:   NLRP1 inflammasome complex assembly [GO:1904784](0|0) (0|0|0)
- 1:   NMS complex assembly [GO:0044768](0|0) (0|0|0)
- 1:   RING-like zinc finger domain-mediated complex assembly [GO:0071536](0|0) (0|0|0)
- 1:   RIP homotypic interaction motif-mediated complex assembly [GO:0071552](0|0) (0|0|0)
- 1:   Rel homology domain-mediated complex assembly [GO:0071531](0|0) (0|0|0)
- 1:   SH2 domain-mediated complex assembly [GO:0071538](0|0) (0|0|0)
- 1:   TCR signalosome assembly [GO:0036399](0|0) (0|0|0)
- 1:   TIR domain-mediated complex assembly [GO:0071523](0|0) (0|0|0)
- 1:   TORC1 complex assembly [GO:1905669](0|0) (0|0|0)
- 1:   VCP-NPL4-UFD1 AAA ATPase complex assembly [GO:1904210](0|0) (0|0|0)
- 1:   Wnt signalosome assembly [GO:1904887](0|0) (0|0|0)
- 1:   Wnt-Frizzled-LRP5/6 complex assembly [GO:1904701](0|0) (0|0|0)
- 1:   Y-shaped link assembly [GO:1905350](0|0) (0|0|0)
- 1:   ankyrin repeat-mediated complex assembly [GO:0071533](0|0) (0|0|0)
- 1:   apoptosome assembly [GO:0097314](0|0) (0|0|0)
- 1:   beta-catenin destruction complex assembly [GO:1904885](0|0) (0|0|0)
- 1:   beta-catenin-TCF complex assembly [GO:1904837](0|0) (4|0|0)
- 1:   ciliary necklace assembly [GO:1905352](0|0) (0|0|0)
- 1:   ciliary transition fiber assembly [GO:1905353](0|0) (0|0|0)
- 1:   eukaryotic translation initiation factor 2 complex assembly [GO:1905143](0|0) (0|0|0)
- 1:   eukaryotic translation initiation factor 2B complex assembly [GO:1905173](0|0) (0|0|0)
- 1:   exon-exon junction complex assembly [GO:1903040](0|0) (0|0|0)
- 1:   gamma-tubulin complex assembly [GO:1902481](0|0) (0|0|0)
- 1:   heterotrimeric G-protein complex assembly [GO:1902605](0|0) (0|0|0)
- 1:   integrin activation [GO:0033622](0|0) (3|2|2)
- 1:   lateral cortical node assembly [GO:1903359](0|0) (0|0|0)
- 1:   mitotic checkpoint complex assembly [GO:1905660](0|0) (0|0|0)
- 1:   origin recognition complex assembly [GO:1902561](0|0) (0|0|0)
- 1:   podosome assembly [GO:0071800](0|0) (3|0|0)
- 1:   protein complex assembly involved in synapse maturation [GO:0090126](0|0) (1|0|0)
- 1:   protein complex oligomerization [GO:0035786](0|0) (3|3|2)
- 1:   pyroptosome complex assembly [GO:1904270](0|0) (0|0|0)
- 1:   starch utilization system complex assembly [GO:0044574](0|0) (0|0|0)
- 1:   zf-TRAF domain-mediated complex assembly [GO:0071534](0|0) (0|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
ALDH-like0.00034140.00003747Direct
Carbohydrate phosphatase0.00000062180.000001337Direct
Cgl1923-like0.000000000012470.00000000001224Direct
Cytochrome c oxidase subunit h0.000000000053010.0000000001619Direct
Cytochrome c oxidase subunit III-like00Direct
EF-hand0.00095660.0000000001248Direct
HydA/Nqo6-like0.00000047240.000002073Direct
Indolic compounds 2,3-dioxygenase-like00Direct
MAPEG domain-like0.000031740.00004196Direct
Prefoldin0.00000000024890.0000000176Direct
RNase A-like00.000000000000003734Direct
Snake toxin-like0.0007930.0004776Direct
SRF-like0.000011230.00001683Direct
Transthyretin (synonym: prealbumin)0.0000000086310.0000000006897Direct
Family A G protein-coupled receptor-like0.45841Inherited
Trimeric LpxA-like enzymes0.00026310.001005Inherited
Histone-fold11Inherited
Thioesterase/thiol ester dehydrase-isomerase0.05670.5352Inherited
Flavoproteins0.022340.1022Inherited
Proton glutamate symport protein0.013740.0006633Inherited
Globin-like0.0055190.0211Inherited
NAD(P)-binding Rossmann-fold domains0.00000000049130.02184Inherited
PRTase-like0.0000089570.00139Inherited
Aquaporin-like0.012390.0004776Inherited
Bcl-2 inhibitors of programmed cell death0.000024560.03888Inherited
SNF-like0.0052470.02651Inherited
Mss4-like0.0000069010.03751Inherited
UBC-like0.17740.009077Inherited
Actin depolymerizing proteins11Inherited
TPR-like0.67660.1812Inherited
SNARE fusion complex0.19220.5873Inherited
Cysteine alpha-hairpin motif0.000010410.08548Inherited
RNI-like0.013070.1629Inherited
S-adenosyl-L-methionine-dependent methyltransferases11Inherited
Thioredoxin-like0.41940.01022Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
ALDH-like0.00061770.00005971Direct
Bacterial tryptophan 2,3-dioxygenase00Direct
Cytochrome c oxidase subunit h0.000000043850.0000001017Direct
Cytochrome c oxidase subunit III-like00Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0.0000007820.000001398Direct
MAPEG domain0.0000170.0000201Direct
Mitochondrial ribosomal protein L51/S25/CI-B8 domain0.00000016710.0000003269Direct
Nq06-like0.00000030030.0000003483Direct
Penta-EF-hand proteins0.00027870Direct
Phosphoribosyltransferases (PRTases)0.000010990.00006615Direct
Prefoldin0.000000034340.0000004584Direct
Ribonuclease A-like0.0000000000000022720.00000000000001449Direct
SelR domain0.0000000000013310.000000000001014Direct
SRF-like0.0000063020.00003421Direct
Transthyretin (synonym: prealbumin)0.000000014960.000000001115Direct
Tyrosine-dependent oxidoreductases0.000000000053340.0001125Direct
Rhodopsin-like0.072951Inherited
Globins0.0046460.01437Inherited
PaaI/YdiI-like0.0019940.00186Inherited
Aquaporin-like0.0081330.0004042Inherited
Bcl-2 inhibitors of programmed cell death0.000044510.03431Inherited
GABA-aminotransferase-like0.0068840.01184Inherited
UBC-related0.18750.0008912Inherited
SNARE fusion complex0.14990.543Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Indolic compounds 2,3-dioxygenase-like0Direct
Cytochrome c oxidase subunit III-like0Direct
TNF-like0Direct
Calpain large subunit, middle domain (domain III)0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
RNase A-like0.000000000000001898Direct
Myosin rod fragments0.000000000000009141Direct
Ctag/Cox110.00000000000001797Direct
F1 ATPase inhibitor, IF1, C-terminal domain0.000000000001452Direct
Cgl1923-like0.000000000006897Direct
EF-hand0.00000000007169Direct
Cytochrome c oxidase subunit h0.00000000009311Direct
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)0.0000000001337Direct
Voltage-gated potassium channels0.0000000001487Direct
DEATH domain0.0000000003464Direct
Transthyretin (synonym: prealbumin)0.0000000004031Direct
IP3 receptor type 1 binding core, domain 20.0000000007748Direct
Composite domain of metallo-dependent hydrolases0.000000005015Direct
Heme chaperone CcmE0.000000006521Direct
Prefoldin0.00000001073Direct
MHC antigen-recognition domain0.0000000674Direct
PDZ domain-like0.00000007653Direct
N-terminal coiled coil domain from apc0.00000008107Direct
Tumor suppressor gene product Apc0.00000008107Direct
Carbohydrate phosphatase0.0000008584Direct
MIR domain0.00000109Direct
HydA/Nqo6-like0.000001339Direct
Cysteine-rich domain0.000002327Direct
SRP190.00000386Direct
SRF-like0.00001121Direct
cAMP-binding domain-like0.00001185Direct
Trimerization domain of TRAF0.00001595Direct
Second domain of FERM0.00001818Direct
ALDH-like0.00002523Direct
MAPEG domain-like0.00002827Direct
Phosphofructokinase0.00002827Direct
Agglutinin HPA-like0.00004348Direct
FtsH protease domain-like0.00004876Direct
S-adenosylmethionine synthetase0.00005637Direct
Metallo-dependent hydrolases0.0001496Direct
Myosin S1 fragment, N-terminal domain0.0001681Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0001889Direct
POZ domain0.000226Direct
CAD & PB1 domains0.0002841Direct
Serine protease inhibitors0.0002845Direct
PheT/TilS domain0.0003012Direct
Snake toxin-like0.0003355Direct
Aquaporin-like0.0003355Direct
14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)0.0003813Direct
I/LWEQ domain0.0004069Direct
AraD/HMP-PK domain-like0.0004382Direct
Proton glutamate symport protein0.000468Direct
Clathrin heavy-chain terminal domain0.0004749Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0005349Direct
Signal peptide-binding domain0.0005843Direct
Nucleoplasmin-like core domain0.0006581Direct
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30.0007103Direct
Trimeric LpxA-like enzymes0.0007157Direct
Nicotinic receptor ligand binding domain-like0.0007237Direct
Fibrinogen coiled-coil and central regions0.0008531Direct
PRTase-like0.0009951Direct
WD40 repeat-like1Inherited
HMG-box0.9953Inherited
FYVE/PHD zinc finger1Inherited
Bromodomain1Inherited
Concanavalin A-like lectins/glucanases0.02719Inherited
BAR/IMD domain-like0.5196Inherited
SH3-domain0.08533Inherited
SET domain0.2407Inherited
Fibronectin type III0.2969Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Protein kinase-like (PK-like)0.04976Inherited
Immunoglobulin0.7157Inherited
HSP20-like chaperones0.2555Inherited
HIT/MYND zinc finger-like0.04492Inherited
SAND domain-like0.1367Inherited
Ribonuclease PH domain 2-like0.2173Inherited
Family A G protein-coupled receptor-like1Inherited
DNA clamp0.01116Inherited
B-box zinc-binding domain0.001396Inherited
"Winged helix" DNA-binding domain0.4759Inherited
SMAD MH1 domain0.007103Inherited
SMAD/FHA domain0.4492Inherited
RmlC-like cupins0.2189Inherited
Histone-fold1Inherited
Putative DNA-binding domain0.06739Inherited
Growth factor receptor domain0.01167Inherited
Inhibitor of apoptosis (IAP) repeat0.002988Inherited
Globin-like0.01599Inherited
WW domain0.003377Inherited
EGF/Laminin0.2861Inherited
L domain-like0.9513Inherited
Single hybrid motif0.0701Inherited
PreATP-grasp domain0.0796Inherited
beta-lactamase/transpeptidase-like0.29Inherited
Glutathione synthetase ATP-binding domain-like0.5501Inherited
Class II aaRS and biotin synthetases0.02824Inherited
YWTD domain0.2869Inherited
PK beta-barrel domain-like0.07709Inherited
Thioesterase/thiol ester dehydrase-isomerase0.457Inherited
NAD(P)-binding Rossmann-fold domains0.01658Inherited
E set domains0.04737Inherited
L-aspartase-like0.001651Inherited
Phosphoenolpyruvate/pyruvate domain0.2073Inherited
(Phosphotyrosine protein) phosphatases II0.8114Inherited
dUTPase-like0.01613Inherited
SRCR-like1Inherited
Outer membrane efflux proteins (OEP)0.004797Inherited
p53 tetramerization domain0.02452Inherited
Flavoproteins0.08102Inherited
Heme-dependent catalase-like0.006439Inherited
PK C-terminal domain-like0.007335Inherited
HRDC-like0.1513Inherited
Spermadhesin, CUB domain0.001731Inherited
GlnB-like0.02192Inherited
Rad51 N-terminal domain-like1Inherited
LDL receptor-like module0.4836Inherited
Rudiment single hybrid motif0.008247Inherited
Transglutaminase, two C-terminal domains0.00132Inherited
NAD kinase/diacylglycerol kinase-like0.001912Inherited
NAD(P)-linked oxidoreductase0.002155Inherited
Connexin430.004797Inherited
SNF-like0.02022Inherited
Bcl-2 inhibitors of programmed cell death0.02993Inherited
ClpP/crotonase0.08529Inherited
C-terminal, gelsolin-like domain of Sec23/241Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.002443Inherited
VHP, Villin headpiece domain0.1118Inherited
Calponin-homology domain, CH-domain1Inherited
GroEL equatorial domain-like0.03579Inherited
GroEL apical domain-like0.0803Inherited
GroEL-intermediate domain like0.1869Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.6748Inherited
Ribosomal protein S5 domain 2-like1Inherited
TPR-like0.1465Inherited
DnaJ/Hsp40 cysteine-rich domain0.004085Inherited
Subdomain of clathrin and coatomer appendage domain0.02322Inherited
GAT-like domain0.1513Inherited
Clathrin adaptor appendage domain0.7951Inherited
vWA-like1Inherited
Quinoprotein alcohol dehydrogenase-like0.1285Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.003615Inherited
Cullin repeat-like0.0803Inherited
Cullin homology domain0.1544Inherited
SNARE-like0.1775Inherited
Kelch motif0.6836Inherited
beta-sandwich domain of Sec23/241Inherited
Helical domain of Sec23/241Inherited
C-terminal autoproteolytic domain of nucleoporin nup980.2266Inherited
Cytokine0.5882Inherited
ARM repeat0.2792Inherited
Tubulin C-terminal domain-like0.00883Inherited
Tubulin nucleotide-binding domain-like0.00883Inherited
Tudor/PWWP/MBT1Inherited
Actin depolymerizing proteins0.9652Inherited
Mss4-like0.02884Inherited
UBC-like0.006726Inherited
Formin homology 2 domain (FH2 domain)0.00883Inherited
ENTH/VHS domain0.01328Inherited
HSP90 C-terminal domain0.009912Inherited
SNARE fusion complex0.5044Inherited
Thioredoxin-like0.007591Inherited
Cysteine alpha-hairpin motif0.06739Inherited
Tropomyosin0.00115Inherited
Cystine-knot cytokines1Inherited
Chaperone J-domain0.4123Inherited
Ankyrin repeat0.1695Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.9894Inherited
t-snare proteins0.9702Inherited
YgfY-like0.04597Inherited
Mitochondrial carrier1Inherited
PLP-dependent transferases0.5495Inherited
Double Clp-N motif0.01509Inherited
Cdc48 domain 2-like1Inherited
ADC-like1Inherited
PH domain-like0.005848Inherited
Interleukin 8-like chemokines0.09578Inherited
RNI-like0.1311Inherited
4Fe-4S ferredoxins0.17Inherited
Terpenoid synthases0.5362Inherited
ACP-like0.6891Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
FAD/NAD(P)-binding domain1Inherited
Cytochrome c0.4453Inherited
OMPA-like0.3678Inherited
SH2 domain0.8957Inherited
Fibrinogen C-terminal domain-like0.3413Inherited
RING/U-box0.03148Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0Direct
    57889,111331
  • 57889 - Cysteine-rich domain
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.000000000000007352Direct
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.00000000000005898Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.00000000000137Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.000000000002907Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.00000000001163Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00000000001748Direct
    49764,48452
  • 49764 - HSP20-like chaperones
  • 48452 - TPR-like
  • 0.000000000081Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.000000000176Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.0000000003479Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.000000000598Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.00000000122Direct
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000002565Direct
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000003419Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.000000005712Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.00000003203Direct
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.0000000523Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000008107Direct
    50729,47031
  • 50729 - PH domain-like
  • 47031 - Second domain of FERM
  • 0.0000001135Direct
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.0000001472Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000181Direct
    48452,46785
  • 48452 - TPR-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0000002089Direct
    49265,56112
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000004005Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0.000001134Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000003061Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.000003241Direct
    90257,57997
  • 90257 - Myosin rod fragments
  • 57997 - Tropomyosin
  • 0.000003325Direct
    53784,53784
  • 53784 - Phosphofructokinase
  • 53784 - Phosphofructokinase
  • 0.000003714Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000004896Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000005101Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000802Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.000008313Direct
    46955,56037
  • 46955 - Putative DNA-binding domain
  • 56037 - PheT/TilS domain
  • 0.00000844Direct
    49785,141086
  • 49785 - Galactose-binding domain-like
  • 141086 - Agglutinin HPA-like
  • 0.00000844Direct
    50891,48452
  • 50891 - Cyclophilin-like
  • 48452 - TPR-like
  • 0.00001088Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.00001205Direct
    57953,49599
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0.00001595Direct
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.00001862Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0000215Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0.00002243Direct
    57997,90257
  • 57997 - Tropomyosin
  • 90257 - Myosin rod fragments
  • 0.0000273Direct
    81324,47473
  • 81324 - Voltage-gated potassium channels
  • 47473 - EF-hand
  • 0.00002788Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.00004392Direct
    82895,57424
  • 82895 - TSP-1 type 1 repeat
  • 57424 - LDL receptor-like module
  • 0.00004732Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0.00004768Direct
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00006017Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.000088Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.00009013Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00009341Direct
    56037,46955
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 0.00009428Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001381Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.0002076Direct
    46955,55681
  • 46955 - Putative DNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0002335Direct
    57567,57603
  • 57567 - Serine protease inhibitors
  • 57603 - FnI-like domain
  • 0.0003012Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0004577Direct
    82199,48452
  • 82199 - SET domain
  • 48452 - TPR-like
  • 0.0004749Direct
    50989,48371
  • 50989 - Clathrin heavy-chain terminal domain
  • 48371 - ARM repeat
  • 0.0004749Direct
    52540,47446
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47446 - Signal peptide-binding domain
  • 0.0005843Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.000611Direct
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 0.0007103Direct
    55666,46915
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0.0007103Direct
    54277,50156
  • 54277 - CAD & PB1 domains
  • 50156 - PDZ domain-like
  • 0.0007103Direct
    46915,54211
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0007103Direct
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.0007415Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.000825Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1215Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.001039Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.3151Inherited
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.05627Inherited
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0.179Inherited
    55979,55979
  • 55979 - DNA clamp
  • 55979 - DNA clamp
  • 0.001465Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.002605Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.04291Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2869Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.006401Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.2869Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2869Inherited
    55666,54791
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.002759Inherited
    54791,50249
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0.002759Inherited
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.02452Inherited
    50800,51621
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0.004885Inherited
    51621,52935
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.005619Inherited
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.6931Inherited
    81324,51735
  • 81324 - Voltage-gated potassium channels
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.004331Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.02993Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.2869Inherited
    47794,52540
  • 47794 - Rad51 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0.006602Inherited
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0.001187Inherited
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.00132Inherited
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.00132Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.101Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.4836Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.1796Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.182Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.1513Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.1544Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1544Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 1Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 1Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 1Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.00883Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.03202Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.001393Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.01773Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.2061Inherited
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0.02067Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.005878Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.7213Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 1Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57889,57889,111331
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    50729,57889,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 9.676e-16Direct
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.000000000000003737Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.000000000000003737Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0000000000004745Direct
    49265,49265,48726
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0000000000479Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.0000000008985Direct
    56112,48726,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.000000002131Direct
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000003419Direct
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.000000007389Direct
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.00000006376Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000008107Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00000008107Direct
    47031,50729,47031
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 47031 - Second domain of FERM
  • 0.0000001135Direct
    50729,47031,50729
  • 50729 - PH domain-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000001135Direct
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000000185Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0000003778Direct
    48726,49265,56112
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000004642Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0.0000005982Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000002057Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.000007546Direct
    90257,57997,90257
  • 90257 - Myosin rod fragments
  • 57997 - Tropomyosin
  • 90257 - Myosin rod fragments
  • 0.00000844Direct
    46955,56037,46955
  • 46955 - Putative DNA-binding domain
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 0.00000844Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.000009555Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.00001205Direct
    53300,53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.00001504Direct
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.00001504Direct
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00001504Direct
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.00001862Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0.00004768Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.00004768Direct
    56037,46955,55681
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.00009428Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001685Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0002535Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000279Direct
    50989,48371,48371
  • 50989 - Clathrin heavy-chain terminal domain
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0003813Direct
    46915,54211,55666
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0.0007103Direct
    54211,55666,46915
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0.0007103Direct
    55666,46915,54211
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0007103Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.000843Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.001331Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2403Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9625Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4083Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2869Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.002279Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.002443Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2869Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.2869Inherited
    55666,54791,50249
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0.002759Inherited
    54211,55666,54791
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.002759Inherited
    50800,51621,52935
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.004885Inherited
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.6146Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0852Inherited
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0.006109Inherited
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.001187Inherited
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.00132Inherited
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.1544Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.1748Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.2266Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1544Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 1Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 1Inherited
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.0329Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.101Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.009556Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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