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Biological Process (BP): receptor-mediated endocytosis

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + 5:   localization [GO:0051179] <10>(91|101) (503|489|298)
+ + + + 4:   establishment of localization [GO:0051234] <6>(78|88) (409|348|184)
+ + + 3:   transport [GO:0006810] <14>(76|87) (402|340|182)
+ + 2:   vesicle-mediated transport [GO:0016192] <28>(22|21) (164|165|99)
+ 1:   endocytosis [GO:0006897] <8>(8|8) (90|102|68)
0:   receptor-mediated endocytosis [GO:0006898] <4>(1|1) (41|43|30)
- 1:   clathrin-dependent endocytosis [GO:0072583] <8>(0|0) (16|13|4)
- 1:   receptor internalization [GO:0031623] <7>(0|0) (19|13|5)
- 1:   receptor-mediated endocytosis of virus by host cell [GO:0019065] <2>(0|0) (2|1|0)
- 1:   receptor-mediated endocytosis involved in cholesterol transport [GO:0090118](0|0) (3|3|3)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Immunoglobulin00.0001525Direct


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
V set domains (antibody variable domain-like)00Direct


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ricin B-like lectins0Direct
Transferrin receptor-like dimerisation domain0Direct
Integrin beta tail domain0Direct
Virus ectodomain0Direct
gp120 core0Direct
EGF/Laminin0.000000000000005554Direct
YWTD domain0.000000000001496Direct
PA domain0.000000000001692Direct
LDL receptor-like module0.0000000005748Direct
Plexin repeat0.00000004092Direct
Growth factor receptor domain0.00000007838Direct
BAR/IMD domain-like0.0000006181Direct
vWA-like0.00000116Direct
Family A G protein-coupled receptor-like0.000002527Direct
Integrin domains0.000015Direct
Clathrin adaptor appendage domain0.00002052Direct
Subdomain of clathrin and coatomer appendage domain0.00002052Direct
Zn-dependent exopeptidases0.00005299Direct
Apolipoprotein A-I0.00006242Direct
C-type lectin-like0.00007255Direct
Immunoglobulin0.000105Direct
Chaperone J-domain0.0002296Direct
Tetraspanin0.0003181Direct
ENTH/VHS domain0.001841Inherited
DNase I-like0.132Inherited
SH3-domain0.231Inherited
EF-hand0.6031Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.05133Inherited
SNARE-like0.9897Inherited
P-domain of calnexin/calreticulin0.005292Inherited
GAT-like domain0.008103Inherited
Concanavalin A-like lectins/glucanases0.942Inherited
PH domain-like0.7549Inherited
E set domains0.4241Inherited
WW domain0.001076Inherited
Hormone receptor domain0.002062Inherited
Hect, E3 ligase catalytic domain0.07063Inherited
Regulator of G-protein signaling, RGS0.4046Inherited
PX domain0.6869Inherited
(Phosphotyrosine protein) phosphatases II0.7139Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0Direct
    56502,56502
  • 56502 - gp120 core
  • 56502 - gp120 core
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    50370,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 0Direct
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    47473,57997
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00000000000009389Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0.0000000000001788Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.000000000001279Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.000000000001279Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.000000000001496Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.00000000001011Direct
    47576,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000000006103Direct
    63825,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 0.000000008358Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.00000004092Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000007999Direct
    57440,56436
  • 57440 - Kringle-like
  • 56436 - C-type lectin-like
  • 0.0000002897Direct
    50370,57440
  • 50370 - Ricin B-like lectins
  • 57440 - Kringle-like
  • 0.0000002897Direct
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.0000003944Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.000003983Direct
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0.000004297Direct
    50729,48350
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.000005878Direct
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.00000682Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.000007898Direct
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.00000999Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00001962Direct
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.00002052Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0.00003144Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.00005299Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0.00005299Direct
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.0001199Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.01524Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1451Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.2384Inherited
    49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
  • 0.005292Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.008103Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.05492Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.002933Inherited
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.02159Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.1297Inherited
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0.132Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50370,56436,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0Direct
    47473,47473,57997
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    56436,56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000000000001463Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.000000000001279Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.000000000001279Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.000000000003937Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.000000000006883Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00000000001011Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0000000002428Direct
    47576,57716,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000000002824Direct
    63825,57184,63825
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0000000006103Direct
    57184,63825,57196
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.00000001582Direct
    57196,57196,49854
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.00000003523Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000005764Direct
    57440,56436,56436
  • 57440 - Kringle-like
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0000002897Direct
    50370,57440,56436
  • 50370 - Ricin B-like lectins
  • 57440 - Kringle-like
  • 56436 - C-type lectin-like
  • 0.0000002897Direct
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.0000004229Direct
    49854,49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.000001825Direct
    49899,49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
  • 0.000002905Direct
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.000006176Direct
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.00002052Direct
    47473,47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.0003448Direct
    57424,57196,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0003448Direct
    57196,57196,63825
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0003448Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.007943Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.02159Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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