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Biological Process (BP): response to stress

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + 2:   biological_process [GO:0008150] <24>
+ 1:   response to stimulus [GO:0050896] <16>(133|153) (688|755|432)
0:   response to stress [GO:0006950] <30>(81|96) (467|443|230)
- 1:   cellular response to stress [GO:0033554] <39>(36|46) (290|225|114)
- 1:   defense response [GO:0006952] <13>(29|31) (139|107|48)
- 1:   response to starvation [GO:0042594] <12>(1|3) (61|41|17)
- 1:   response to osmotic stress [GO:0006970] <7>(6|7) (49|25|8)
- 1:   response to oxidative stress [GO:0006979] <7>(16|16) (81|40|17)
- 1:   response to wounding [GO:0009611] <7>(10|10) (107|107|76)
- 1:   response to water deprivation [GO:0009414] <5>(4|4) (17|6|1)
- 1:   response to cold [GO:0009409] <4>(3|4) (26|15|5)
- 1:   response to fluid shear stress [GO:0034405] <4>(0|0) (9|3|0)
- 1:   stress response to metal ion [GO:0097501] <4>(1|1) (13|7|4)
- 1:   multicellular organismal response to stress [GO:0033555] <3>(0|1) (19|16|10)
- 1:   response to heat [GO:0009408] <3>(5|9) (36|16|7)
- 1:   response to hypoxia [GO:0001666] <3>(7|8) (43|38|23)
- 1:   response to immobilization stress [GO:0035902] <3>(0|0) (1|0|0)
- 1:   response to topologically incorrect protein [GO:0035966] <3>(2|1) (35|21|10)
- 1:   response to anoxia [GO:0034059] <2>(0|0) (1|1|0)
- 1:   muscle hypertrophy in response to stress [GO:0003299] <1>(0|0) (0|0|0)
- 1:   response to caloric restriction [GO:0061771] <1>(0|0) (2|0|0)
- 1:   response to hydrostatic pressure [GO:0051599] <1>(0|0) (0|0|0)
- 1:   response to hyperoxia [GO:0055093] <1>(0|0) (6|0|0)
- 1:   response to isolation stress [GO:0035900] <1>(0|0) (0|0|0)
- 1:   response to nitrosative stress [GO:0051409] <1>(0|0) (3|2|1)
- 1:   response to sterol depletion [GO:0006991] <1>(0|0) (4|0|0)
- 1:   stress response to acid chemical [GO:0097532] <1>(0|0) (0|0|0)
- 1:   phage shock [GO:0009271](0|0) (1|0|0)
- 1:   response to flooding [GO:0009413](0|0) (0|0|0)
- 1:   response to herbicide [GO:0009635](1|0) (3|1|0)
- 1:   response to high population density [GO:0090664](0|0) (0|0|0)
- 1:   response to ischemia [GO:0002931](0|0) (4|0|0)
- 1:   response to psychosocial stress [GO:1990911](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
4-helical cytokines0.000017190.00006542Direct
Annexin0.00082250.0000775Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0000048290.0009099Direct
CI-2 family of serine protease inhibitors0.000000035890.0000002227Direct
Cu,Zn superoxide dismutase-like0.00000000059320.00000000000001763Direct
Cyclotides00Direct
Defensin-like00Direct
Delta-sleep-inducing peptide immunoreactive peptide0.000084740.0000001157Direct
DNA-glycosylase0.0000038770Direct
Globin-like0.00061050.00009878Direct
Heme-dependent catalase-like0.00001870.000000006154Direct
Heme-dependent peroxidases0.00000040710.00003891Direct
Histone-fold0.0000000000000031440.0000007769Direct
HSP20-like chaperones00.000000000000007296Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain00Direct
Leucine zipper domain0.00011090.000001192Direct
Lysozyme-like0.00000059050.00000001536Direct
Nudix0.0001090.0003027Direct
Osmotin, thaumatin-like protein0.00000044430.0001238Direct
RNase A-like0.00000000030640.00000000003886Direct
Scorpion toxin-like00Direct
TFB5-like0.00025380.0009467Direct
The spindle assembly checkpoint protein mad20.0000000055680.0007256Direct
Thioredoxin-like0.00011740.00000004147Direct
UBC-like0.0000003180.000000004507Direct
Uracil-DNA glycosylase-like0.0000000000000031440Direct
Cytidine deaminase-like0.37640.0002803Inherited
HLH, helix-loop-helix DNA-binding domain0.45571Inherited
Metallo-dependent hydrolases0.69821Inherited
Metallothionein11Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.110.8515Inherited
Cytochrome P4500.53431Inherited
Bcl-2 inhibitors of programmed cell death0.079710.02683Inherited
Trypsin-like serine proteases0.0029430.000583Inherited
Serpins0.0051840.0006136Inherited
Cystatin/monellin0.094350.0000000008073Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.003450.4332Inherited
Mss4-like0.014370.08213Inherited
C-type lectin-like0.000021520.002045Inherited
N-acetylmuramoyl-L-alanine amidase-like0.015370.00000002573Inherited
WD40 repeat-like0.98541Inherited
E set domains0.75911Inherited
Lipocalins0.21760.03554Inherited
Sec1/munc18-like (SM) proteins0.65040.5897Inherited
ERO1-like0.0054460.0008273Inherited
Aquaporin-like0.015820.0291Inherited
Class I glutamine amidotransferase-like0.4051Inherited
Mitochondrial carrier0.57841Inherited
NAD(P)-linked oxidoreductase0.16281Inherited
Peptide methionine sulfoxide reductase0.0031810.0002564Inherited
DNase I-like0.0031640.6394Inherited
Ubiquitin-like0.00040380.3465Inherited
alpha/beta-Hydrolases11Inherited
P-loop containing nucleoside triphosphate hydrolases0.88410.0000000002591Inherited
Radical SAM enzymes0.18481Inherited
DNA/RNA polymerases0.032660.00000000002699Inherited
ALDH-like0.45991Inherited
Apolipoprotein A-I0.011750.00000009607Inherited
Chlorophyll a-b binding protein0.030850.2261Inherited
Nucleic acid-binding proteins0.0011320Inherited
Cytokine0.38530.1686Inherited
Insulin-like0.96991Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.086491Inherited
FAD/NAD(P)-binding domain0.076241Inherited
HydB/Nqo4-like0.015770.1807Inherited
ParB/Sulfiredoxin0.0000037610.07073Inherited
Ribonuclease H-like0.00006850.002779Inherited
Restriction endonuclease-like0.26990.00000000001082Inherited
Xylose isomerase-like0.34210.303Inherited
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0.060910.1044Inherited
(Trans)glycosidases0.00087390.2186Inherited
Interleukin 8-like chemokines0.1170.007735Inherited
Family A G protein-coupled receptor-like11Inherited
2-methylcitrate dehydratase PrpD0.018340.07469Inherited
Immunoglobulin11Inherited
Saposin0.00000065840.05282Inherited
Clavaminate synthase-like0.0042180.9153Inherited
NAP-like0.0450.04546Inherited
EF-hand0.99821Inherited
Phosphoglycerate kinase0.067650.136Inherited
Protein kinase-like (PK-like)0.10120.1155Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
3-Methyladenine DNA glycosylase I (Tag)0.0000000061740.0000001286Direct
AlkB-like0.000000000000081240.000000000000412Direct
Bee venom hyaluronidase0.0000094030.000000000003354Direct
C-type lectin domain0.000089220.0000001182Direct
C-type lysozyme0.000035660.000001651Direct
CAF1-like ribonuclease0.000260.00001378Direct
CCP-like0.00000058170.00000008205Direct
CI-2 family of serine protease inhibitors0.000000078080.0000003735Direct
Cu,Zn superoxide dismutase-like0.0000000010390.0000000000000117Direct
Defensin00.0000000000001595Direct
Delta-sleep-inducing peptide immunoreactive peptide0.0001170.0000002613Direct
DNA gyrase/MutL, N-terminal domain0.000000000095590.000000001187Direct
DNA repair glycosylase, 2 C-terminal domains00.00000001886Direct
DnaQ-like 3'-5' exonuclease0.00093410.0000002227Direct
Endonuclease IV0.000011520.000003904Direct
Globins0.00078580.00009013Direct
Glutathione peroxidase-like0.00000013740.00000000000002002Direct
Heme-dependent catalases0.000023820.000000004643Direct
HSP2000Direct
Insect defensins00Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain00Direct
Interferons/interleukin-10 (IL-10)0.00000000000028230Direct
Kalata B10.000000000095590.0000000006719Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0.0007120.000000000000001589Direct
Leucine zipper domain0.00017070.0000007982Direct
ML domain0.00011210.0004533Direct
Mug-like0.000000000093550.000000000009516Direct
Nucleosome core histones0.000000000022020.000000000006211Direct
Osmotin, thaumatin-like protein0.00000072390.0001005Direct
Plant defensins0.0000000000000087080.0000000000001444Direct
RecA protein-like (ATPase-domain)0.00024860.00000000001382Direct
Ribonuclease A-like0.00000000054780.00000000002877Direct
RuvC resolvase0.0000011310.000003904Direct
SelR domain0.00024860.00001097Direct
The spindle assembly checkpoint protein mad20.00000002280.0003547Direct
UBC-related0.000003650.00008558Direct
Uracil-DNA glycosylase0.00048790.0000002613Direct
HLH, helix-loop-helix DNA-binding domain0.46441Inherited
Renal dipeptidase0.96760.9494Inherited
Metallothionein11Inherited
Proteasome subunits0.075380.4357Inherited
Cytochrome P4500.55561Inherited
Bcl-2 inhibitors of programmed cell death0.094080.02259Inherited
Eukaryotic proteases0.0063940.00002963Inherited
MoCo biosynthesis proteins0.0063860.1649Inherited
Serpins0.0075670.0004794Inherited
Cathelicidin motif0.0017470.000001186Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.00078650.422Inherited
C1 set domains (antibody constant domain-like)0.0020430Inherited
TBP-associated factors, TAFs0.0078481Inherited
N-acetylmuramoyl-L-alanine amidase-like0.016140.00000001958Inherited
GABARAP-like0.0091530.01378Inherited
WD40-repeat0.94181Inherited
Retinol binding protein-like0.026080.0009588Inherited
Annexin0.0011010.00006048Inherited
Sec1/munc18-like (SM) proteins0.65320.5405Inherited
ERO1-like0.0074070.001217Inherited
Tetratricopeptide repeat (TPR)11Inherited
Fibroblast growth factors (FGF)0.64381Inherited
Ubiquitin-related0.061980.000008672Inherited
Aquaporin-like0.01960.09337Inherited
DJ-1/PfpI0.38850.3423Inherited
Mitochondrial carrier0.76041Inherited
Thioltransferase0.16310.00251Inherited
Aldo-keto reductases (NADP)0.36091Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.1160.2999Inherited
Peptide methionine sulfoxide reductase0.0033460.0002097Inherited
Long-chain cytokines0.65270.4018Inherited
MutT-like0.0021620.007638Inherited
G proteins0.71241Inherited
ALDH-like0.63751Inherited
Apolipoprotein A-I0.0012640.000001119Inherited
Chlorophyll a-b binding protein0.061790.3554Inherited
Cold shock DNA-binding domain-like0.0029490.7739Inherited
Glycogenin0.0063860.07638Inherited
Trehalose-6-phosphate synthase, OtsA0.0011160.01615Inherited
C5 cytosine-specific DNA methylase, DCM0.00017070.02531Inherited
IF2B-like0.69490.5729Inherited
Insulin-like0.94821Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.084671Inherited
Nqo4-like0.012210.08755Inherited
TFB5-like0.00042890.001307Inherited
DNase I-like0.0063860.0000001268Inherited
Endonuclease III0.044390.000023Inherited
Ribonucleotide reductase-like0.18080.2973Inherited
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0.079770.1223Inherited
Interleukin 8-like chemokines0.15750.006111Inherited
Rhodopsin-like11Inherited
Short-chain cytokines11Inherited
2-methylcitrate dehydratase PrpD0.050070.1426Inherited
Interleukin 17F, IL-17F0.79760.8899Inherited
Interleukin-1 (IL-1)0.083550.000000003179Inherited
NAP-like0.063360.07249Inherited
S100 proteins0.25030.2042Inherited
Phosphoglycerate kinase0.10380.1786Inherited
Protein kinases, catalytic subunit0.1190.2856Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Scorpion toxin-like0Direct
FLJ32549 domain-like0Direct
Nucleic acid-binding proteins0Direct
Uracil-DNA glycosylase-like0Direct
WGR domain-like0Direct
GroEL equatorial domain-like0Direct
DNA repair protein MutS, domain III0Direct
MHC antigen-recognition domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Domain of poly(ADP-ribose) polymerase0Direct
Ribosomal protein S5 domain 2-like0Direct
GroEL-intermediate domain like0Direct
Crambin-like0Direct
YAP1 redox domain0Direct
BRCT domain0Direct
DNA-glycosylase0Direct
GroEL apical domain-like0Direct
Cyclotides0Direct
Defensin-like0Direct
HSP90 C-terminal domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
FLJ32549 C-terminal domain-like0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
HSP20-like chaperones0.000000000000003737Direct
DNA repair protein MutS, domain I0.000000000000005554Direct
Cu,Zn superoxide dismutase-like0.000000000000009141Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0.000000000000117Direct
5' to 3' exonuclease, C-terminal subdomain0.0000000000002508Direct
RING/U-box0.0000000000004243Direct
N-terminal domain of MutM-like DNA repair proteins0.0000000000004431Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.000000000002514Direct
Restriction endonuclease-like0.000000000006088Direct
p53 tetramerization domain0.00000000001057Direct
Chitinase insertion domain0.00000000001057Direct
DNA/RNA polymerases0.00000000001533Direct
Methylated DNA-protein cysteine methyltransferase domain0.00000000002051Direct
RNase A-like0.00000000002208Direct
P-loop containing nucleoside triphosphate hydrolases0.0000000001496Direct
DNA repair protein MutS, domain II0.0000000001636Direct
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.0000000001636Direct
HMG-box0.0000000001947Direct
Cystatin/monellin0.0000000004725Direct
RuvA domain 2-like0.0000000009646Direct
Fe,Mn superoxide dismutase (SOD), C-terminal domain0.000000001566Direct
Fe,Mn superoxide dismutase (SOD), N-terminal domain0.000000001566Direct
UBC-like0.000000002696Direct
Heme-dependent catalase-like0.000000003698Direct
Lysozyme-like0.000000009341Direct
ATP-dependent DNA ligase DNA-binding domain0.0000000107Direct
N-acetylmuramoyl-L-alanine amidase-like0.00000001575Direct
Zinc finger domain of DNA polymerase-alpha0.00000001575Direct
Rad51 N-terminal domain-like0.00000002271Direct
PIN domain-like0.00000002478Direct
Thioredoxin-like0.00000002548Direct
HIV integrase-binding domain0.00000003752Direct
Apolipoprotein A-I0.00000005961Direct
Delta-sleep-inducing peptide immunoreactive peptide0.00000007194Direct
XPC-binding domain0.00000007194Direct
S13-like H2TH domain0.0000001358Direct
CI-2 family of serine protease inhibitors0.0000001396Direct
DNA clamp0.0000001672Direct
DNA helicase RuvA subunit, C-terminal domain0.0000001845Direct
Cystine-knot cytokines0.0000002079Direct
Glutamine synthetase/guanido kinase0.0000002736Direct
Seven-hairpin glycosidases0.0000002783Direct
Histone-fold0.0000004954Direct
Actin-like ATPase domain0.000000576Direct
Somatomedin B domain0.0000007327Direct
Leucine zipper domain0.0000007642Direct
DNA mismatch repair protein MutL0.000001153Direct
Guanido kinase N-terminal domain0.000001563Direct
Satiety factor CART (cocaine and amphetamine regulated transcript)0.000001785Direct
BRCA2 helical domain0.000001846Direct
BRCA2 tower domain0.000001846Direct
C-terminal domain of Ku800.000002047Direct
RecA protein, C-terminal domain0.000002338Direct
DNA polymerase beta, N-terminal domain-like0.000002338Direct
Heparin-binding domain from vascular endothelial growth factor0.000004737Direct
p53-like transcription factors0.000007159Direct
HRDC-like0.00001365Direct
SPOC domain-like0.00002557Direct
Heme-dependent peroxidases0.0000262Direct
Rad50 coiled-coil Zn hook0.00003497Direct
4-helical cytokines0.00004444Direct
post-AAA+ oligomerization domain-like0.00005207Direct
Annexin0.00005276Direct
Globin-like0.00006748Direct
ADP-ribosylation0.0000683Direct
PsbU/PolX domain-like0.00007691Direct
"Winged helix" DNA-binding domain0.0000783Direct
Osmotin, thaumatin-like protein0.00008488Direct
CarD-like0.00008503Direct
Nitric oxide (NO) synthase oxygenase domain0.0001435Direct
TRCF domain-like0.0001627Direct
GLA-domain0.0001779Direct
Peptide methionine sulfoxide reductase0.0001781Direct
Cytidine deaminase-like0.0001951Direct
Nudix0.000211Direct
JAB1/MPN domain0.0002482Direct
Sec63 N-terminal domain-like0.0002587Direct
Fibrinogen coiled-coil and central regions0.0003026Direct
Trypsin-like serine proteases0.0004108Direct
Serpins0.0004327Direct
Toll/Interleukin receptor TIR domain0.0004462Direct
The spindle assembly checkpoint protein mad20.0005129Direct
ERO1-like0.0005866Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0006463Direct
Serum albumin-like0.0006703Direct
Fzo-like conserved region0.0006731Direct
TFB5-like0.0006731Direct
Allene oxide cyclase-like0.0006763Direct
vWA-like0.000727Direct
LexA/Signal peptidase0.0007723Direct
GIY-YIG endonuclease0.0007797Direct
Nicotinate/Quinolinate PRTase N-terminal domain-like0.0008687Direct
Functional domain of the splicing factor Prp180.0008903Direct
RNA-binding domain, RBD1Inherited
Cation efflux protein cytoplasmic domain-like0.07403Inherited
Cation efflux protein transmembrane domain-like0.07727Inherited
Clavaminate synthase-like0.817Inherited
TPR-like1Inherited
Cysteine proteinases0.4894Inherited
beta-beta-alpha zinc fingers1Inherited
HMA, heavy metal-associated domain0.058Inherited
ABC transporter transmembrane region1Inherited
Band 7/SPFH domain0.7467Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
RNase III domain-like0.111Inherited
PAZ domain1Inherited
ENT-like0.01506Inherited
dsRNA-binding domain-like0.01009Inherited
Elafin-like0.3217Inherited
Flavoproteins0.05748Inherited
PYP-like sensor domain (PAS domain)1Inherited
Ricin B-like lectins0.01049Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00169Inherited
Riboflavin synthase domain-like0.003261Inherited
Calpain large subunit, middle domain (domain III)1Inherited
Histidine-containing phosphotransfer domain, HPT domain1Inherited
Methyl-accepting chemotaxis protein (MCP) signaling domain1Inherited
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.2406Inherited
Activating enzymes of the ubiquitin-like proteins0.7485Inherited
B-box zinc-binding domain0.01438Inherited
Transcription factor STAT-4 N-domain0.007478Inherited
STAT0.008123Inherited
Immunoglobulin1Inherited
NAP-like0.03515Inherited
EF-G C-terminal domain-like0.8706Inherited
Class II aaRS and biotin synthetases1Inherited
Putative DNA-binding domain1Inherited
Homeodomain-like1Inherited
Nuclear receptor ligand-binding domain1Inherited
Double Clp-N motif0.01529Inherited
Growth factor receptor domain1Inherited
Nucleotide cyclase1Inherited
Cytochrome P4501Inherited
PAP/OAS1 substrate-binding domain0.1865Inherited
Radical SAM enzymes1Inherited
Ribonuclease PH domain 2-like0.8002Inherited
Zn-dependent exopeptidases1Inherited
Plant lectins/antimicrobial peptides0.02198Inherited
TNF receptor-like0.7408Inherited
LysM domain0.01089Inherited
Complement control module/SCR domain0.05517Inherited
Concanavalin A-like lectins/glucanases0.9661Inherited
Caspase-like0.002359Inherited
PapD-like0.006796Inherited
SAP domain0.002359Inherited
Plant invertase/pectin methylesterase inhibitor0.2792Inherited
Snake toxin-like1Inherited
Pectin lyase-like1Inherited
SMAD MH1 domain1Inherited
Glycoside hydrolase/deacetylase1Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.3655Inherited
TSP-1 type 1 repeat1Inherited
TSP type-3 repeat0.04365Inherited
Tetrahydrobiopterin biosynthesis enzymes-like0.636Inherited
Sialidases0.6679Inherited
Assembly domain of cartilage oligomeric matrix protein0.005096Inherited
EGF/Laminin1Inherited
FnI-like domain0.0248Inherited
Cysteine-rich domain1Inherited
Voltage-gated potassium channels1Inherited
EB1 dimerisation domain-like0.4993Inherited
DBL homology domain (DH-domain)1Inherited
Galactose-binding domain-like0.9749Inherited
Mss4-like0.0647Inherited
Bactericidal permeability-increasing protein, BPI0.01529Inherited
SH2 domain1Inherited
Triple coiled coil domain of C-type lectins0.07521Inherited
Bromodomain0.8592Inherited
C-type lectin-like0.001475Inherited
Formin homology 2 domain (FH2 domain)0.631Inherited
FF domain0.3248Inherited
DHS-like NAD/FAD-binding domain0.2508Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.7537Inherited
DNA-binding protein LAG-1 (CSL)0.5752Inherited
Notch domain0.1886Inherited
A DNA-binding domain in eukaryotic transcription factors0.00145Inherited
PAH2 domain0.1966Inherited
Chaperone J-domain0.2258Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Alpha-macroglobulin receptor domain0.08166Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
Nicotinic receptor ligand binding domain-like1Inherited
ARM repeat0.257Inherited
HD-domain/PDEase-like1Inherited
eIF-2-alpha, C-terminal domain0.288Inherited
eIF2alpha middle domain-like0.288Inherited
Inhibitor of apoptosis (IAP) repeat0.0043Inherited
KA1-like0.6064Inherited
CBS-domain pair0.424Inherited
Amine oxidase catalytic domain0.008932Inherited
Amine oxidase N-terminal region0.008932Inherited
GAS2 domain-like0.9415Inherited
alpha-ketoacid dehydrogenase kinase, N-terminal domain0.01149Inherited
AhpD-like0.04555Inherited
TGS-like0.2895Inherited
CoA-dependent acyltransferases1Inherited
Calponin-homology domain, CH-domain1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
CheY-like1Inherited
PEP carboxykinase N-terminal domain0.1571Inherited
Nop domain0.2725Inherited
WD40 repeat-like1Inherited
Methuselah ectodomain0.003767Inherited
PEP carboxykinase-like0.2406Inherited
Carbamoyl phosphate synthetase, large subunit connection domain0.4292Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.4528Inherited
Arginase/deacetylase0.01048Inherited
TAZ domain0.1197Inherited
Frataxin/Nqo15-like0.007011Inherited
Cryptochrome/photolyase FAD-binding domain0.003Inherited
Cryptochrome/photolyase, N-terminal domain0.007368Inherited
Insulin-like1Inherited
Carbonic anhydrase0.8879Inherited
E set domains1Inherited
Ferritin-like0.4345Inherited
BEACH domain0.07403Inherited
all-alpha NTP pyrophosphatases0.1341Inherited
FAD-dependent thiol oxidase0.1136Inherited
Sec1/munc18-like (SM) proteins0.5066Inherited
Transducin (alpha subunit), insertion domain1Inherited
IP3 receptor type 1 binding core, domain 20.1402Inherited
Subunits of heterodimeric actin filament capping protein Capz0.3045Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.7131Inherited
PUG domain-like0.1012Inherited
HCP-like0.9987Inherited
Mannose 6-phosphate receptor domain0.03386Inherited
HIT/MYND zinc finger-like0.6202Inherited
MIR domain0.058Inherited
Metallo-hydrolase/oxidoreductase0.8617Inherited
HSP40/DnaJ peptide-binding domain0.002569Inherited
DnaJ/Hsp40 cysteine-rich domain0.1253Inherited
SAM/Pointed domain1Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
POZ domain0.996Inherited
Hemocyanin, N-terminal domain0.04845Inherited
Trimeric LpxA-like enzymes0.9875Inherited
GTPase activation domain, GAP1Inherited
Metallothionein1Inherited
Class I glutamine amidotransferase-like1Inherited
Metallo-dependent hydrolases1Inherited
Aquaporin-like0.02224Inherited
NAD(P)-linked oxidoreductase0.9186Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.3258Inherited
Rubredoxin-like0.1525Inherited
Mitochondrial carrier0.9195Inherited
EAL domain-like1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions1Inherited
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30.01459Inherited
BAR/IMD domain-like1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
Periplasmic binding protein-like I1Inherited
Hormone receptor domain1Inherited
CalX-like0.001041Inherited
Bcl-2 inhibitors of programmed cell death0.02047Inherited
ASF1-like0.002576Inherited
ERP29 C domain-like0.01006Inherited
Multidrug efflux transporter AcrB transmembrane domain1Inherited
F-box domain1Inherited
PLC-like phosphodiesterases1Inherited
DEATH domain0.01381Inherited
SMAD/FHA domain0.003157Inherited
Protein kinase-like (PK-like)0.09194Inherited
TNF-like1Inherited
CCCH zinc finger1Inherited
TRAF domain-like0.146Inherited
Cap-Gly domain0.2768Inherited
SH3-domain1Inherited
PDZ domain-like1Inherited
Hook domain0.5869Inherited
Rhomboid-like0.002161Inherited
Subtilisin-like0.885Inherited
SWIB/MDM2 domain0.1841Inherited
FYVE/PHD zinc finger1Inherited
Chromo domain-like0.1036Inherited
Phosphoglycerate mutase-like1Inherited
Phospholipase D/nuclease0.6717Inherited
ACT-like1Inherited
Eukaryotic type KH-domain (KH-domain type I)0.8023Inherited
WRKY DNA-binding domain0.03554Inherited
Ran binding protein zinc finger-like0.01247Inherited
DNA-binding domain0.1001Inherited
Cupredoxins1Inherited
ACP-like1Inherited
Acetyl-CoA synthetase-like1Inherited
MFS general substrate transporter1Inherited
SRF-like0.9714Inherited
Ankyrin repeat0.6974Inherited
alpha-D-mannose-specific plant lectins0.1133Inherited
Acid proteases1Inherited
alpha/beta-Hydrolases1Inherited
SGNH hydrolase1Inherited
Prokaryotic type KH domain (KH-domain type II)0.6029Inherited
Retrovirus zinc finger-like domains1Inherited
Calcium-dependent phosphotriesterase1Inherited
Frizzled cysteine-rich domain1Inherited
Midkine0.07403Inherited
Plexin repeat1Inherited
Composite domain of metallo-dependent hydrolases0.6581Inherited
Fibrinogen C-terminal domain-like0.1306Inherited
Serine protease inhibitors0.01683Inherited
Invertebrate chitin-binding proteins0.03515Inherited
Connexin430.04523Inherited
Transglutaminase, two C-terminal domains0.2123Inherited
Integrin domains1Inherited
Integrin alpha N-terminal domain0.8529Inherited
LCCL domain0.03318Inherited
Phenylalanine zipper0.7476Inherited
L domain-like1Inherited
Lipoxigenase0.01433Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)1Inherited
Cytokine0.1359Inherited
PGBD-like0.05286Inherited
Hemopexin-like domain0.2242Inherited
LigT-like0.07102Inherited
Intermediate filament protein, coiled coil region0.2804Inherited
Lipocalins0.02728Inherited
NAD kinase/diacylglycerol kinase-like1Inherited
Integrin beta tail domain0.9178Inherited
Kringle-like0.005705Inherited
Terpenoid cyclases/Protein prenyltransferases0.04534Inherited
Fibronectin type III1Inherited
Plakin repeat1Inherited
Terpenoid synthases1Inherited
Spectrin repeat1Inherited
Type II DNA topoisomerase0.1244Inherited
Homodimeric domain of signal transducing histidine kinase1Inherited
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.01309Inherited
ALDH-like0.9665Inherited
Chlorophyll a-b binding protein0.1847Inherited
NAC domain0.02774Inherited
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase1Inherited
PP2C-like1Inherited
Mannose-binding lectins0.5204Inherited
LDH C-terminal domain-like0.7055Inherited
Inosine monophosphate dehydrogenase (IMPDH)0.925Inherited
Thiolase-like1Inherited
DNA-binding pseudobarrel domain1Inherited
BAG domain0.1444Inherited
Sigma3 and sigma4 domains of RNA polymerase sigma factors0.3707Inherited
Sigma2 domain of RNA polymerase sigma factors0.3707Inherited
mRNA decapping enzyme DcpS N-terminal domain0.4716Inherited
NagB/RpiA/CoA transferase-like0.885Inherited
DNA methylase specificity domain0.006271Inherited
Rhodanese/Cell cycle control phosphatase1Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase1Inherited
Hairpin loop containing domain-like0.1925Inherited
Cullin repeat-like0.05455Inherited
Cullin homology domain0.00552Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
PA domain0.8453Inherited
P-domain of calnexin/calreticulin0.3388Inherited
Quinoprotein alcohol dehydrogenase-like0.007337Inherited
Zinc beta-ribbon0.4155Inherited
CRAL/TRIO domain1Inherited
(Trans)glycosidases0.1782Inherited
Heme oxygenase-like0.1664Inherited
GST C-terminal domain-like0.9852Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01437Inherited
YdgH-like0.1012Inherited
Nucleoside diphosphate kinase, NDK0.6273Inherited
Nicotinate/Quinolinate PRTase C-terminal domain-like0.008358Inherited
ParB/Sulfiredoxin0.05545Inherited
HydB/Nqo4-like0.1461Inherited
Protein serine/threonine phosphatase 2C, C-terminal domain0.1809Inherited
4Fe-4S ferredoxins1Inherited
FAD/NAD(P)-binding domain1Inherited
WW domain1Inherited
PHP domain-like0.01454Inherited
C-terminal UvrC-binding domain of UvrB0.02986Inherited
DNA topoisomerase IV, alpha subunit0.001729Inherited
Macro domain-like0.1266Inherited
DNase I-like0.5522Inherited
Prokaryotic type I DNA topoisomerase0.08579Inherited
N-terminal coiled coil domain from apc0.2082Inherited
Tumor suppressor gene product Apc0.2082Inherited
Xylose isomerase-like0.251Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.5816Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Calcium ATPase, transmembrane domain M0.8166Inherited
Calcium ATPase, transduction domain A0.8978Inherited
HAD-like0.4637Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.6408Inherited
Doublecortin (DC)0.03039Inherited
Ypt/Rab-GAP domain of gyp1p1Inherited
Ribosomal protein S3 C-terminal domain0.03946Inherited
FAS1 domain0.06338Inherited
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0.08284Inherited
SpoIIaa-like0.145Inherited
Family A G protein-coupled receptor-like1Inherited
FAT domain of focal adhesion kinase0.02986Inherited
Second domain of FERM1Inherited
Saposin0.04102Inherited
2-methylcitrate dehydratase PrpD0.05866Inherited
Crisp domain-like0.06008Inherited
RNI-like0.09065Inherited
Anaphylotoxins (complement system)0.4175Inherited
Ribonuclease H-like0.002016Inherited
Tudor/PWWP/MBT0.201Inherited
Nucleotidyltransferase0.01081Inherited
ADC-like0.06875Inherited
Ubiquitin-like0.2888Inherited
Cdc48 domain 2-like0.0226Inherited
Zn-binding ribosomal proteins0.8826Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
Hect, E3 ligase catalytic domain0.0453Inherited
UBA-like0.06012Inherited
Ada DNA repair protein, N-terminal domain (N-Ada 10)0.007407Inherited
Nucleoplasmin-like core domain0.05169Inherited
XRCC4, N-terminal domain0.06269Inherited
BSD domain-like0.1735Inherited
ssDNA-binding transcriptional regulator domain0.01496Inherited
Recombination protein RecR0.08755Inherited
TATA-box binding protein-like0.1331Inherited
FMT C-terminal domain-like0.1978Inherited
XRCC4, C-terminal oligomerization domain0.03024Inherited
Cyclophilin-like1Inherited
cAMP-binding domain-like1Inherited
EF-hand1Inherited
Interleukin 8-like chemokines0.005706Inherited
PH domain-like1Inherited
Multidrug resistance efflux transporter EmrE1Inherited
Periplasmic binding protein-like II1Inherited
Spermadhesin, CUB domain0.9502Inherited
Myosin rod fragments0.8932Inherited
Rap/Ran-GAP1Inherited
VHL0.006271Inherited
SRCR-like0.006553Inherited
Phosphoglycerate kinase0.1088Inherited
Acyl-CoA binding protein0.2105Inherited
Mitochondrial cytochrome c oxidase subunit IV0.2639Inherited
Kix domain of CBP (creb binding protein)0.5752Inherited
Nuclear receptor coactivator interlocking domain1Inherited
NTF2-like1Inherited
Metallo-dependent phosphatases1Inherited
PriA/YqbF domain0.7063Inherited
GINS helical bundle-like0.7556Inherited
14-3-3 protein0.3051Inherited
Cyclin-like0.03804Inherited
E2F-DP heterodimerization region0.02491Inherited
Polo-box domain0.003767Inherited
HIT-like0.9366Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49879,52113
  • 49879 - SMAD/FHA domain
  • 52113 - BRCT domain
  • 0Direct
    46785,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    50998,56112
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    49899,90188
  • 49899 - Concanavalin A-like lectins/glucanases
  • 90188 - Somatomedin B domain
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    63877,81321
  • 63877 - Methuselah ectodomain
  • 81321 - Family A G protein-coupled receptor-like
  • 0Direct
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    48452,52833
  • 48452 - TPR-like
  • 52833 - Thioredoxin-like
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0Direct
    52540,52058
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52058 - L domain-like
  • 0Direct
    58006,57196
  • 58006 - Assembly domain of cartilage oligomeric matrix protein
  • 57196 - EGF/Laminin
  • 0Direct
    69848,49785
  • 69848 - LCCL domain
  • 49785 - Galactose-binding domain-like
  • 0Direct
    47473,88713
  • 47473 - EF-hand
  • 88713 - Glycoside hydrolase/deacetylase
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50370,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 0Direct
    46946,57716
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52540,49899
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    46934,56219
  • 46934 - UBA-like
  • 56219 - DNase I-like
  • 0Direct
    143503,54236
  • 143503 - PUG domain-like
  • 54236 - Ubiquitin-like
  • 0Direct
    51695,55550
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 0Direct
    55785,88633
  • 55785 - PYP-like sensor domain (PAS domain)
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    52113,56672
  • 52113 - BRCT domain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0Direct
    142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0Direct
    57440,81901
  • 57440 - Kringle-like
  • 81901 - HCP-like
  • 0Direct
    57535,49899
  • 57535 - Complement control module/SCR domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    158548,160651
  • 158548 - FLJ32549 domain-like
  • 160651 - FLJ32549 C-terminal domain-like
  • 0Direct
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    57850,50978
  • 57850 - RING/U-box
  • 50978 - WD40 repeat-like
  • 0Direct
    58113,58113
  • 58113 - Apolipoprotein A-I
  • 58113 - Apolipoprotein A-I
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0.000000000000117Direct
    54495,54211
  • 54495 - UBC-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0000000000001852Direct
    81624,46946
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 0.0000000000008846Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000000000002514Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.00000000001057Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.00000000001057Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0.00000000001205Direct
    53155,46767
  • 53155 - Methylated DNA-protein cysteine methyltransferase domain
  • 46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain
  • 0.00000000002051Direct
    50249,47781
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0.00000000006338Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000000000765Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.0000000001997Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0000000001997Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0000000005734Direct
    46609,54719
  • 46609 - Fe,Mn superoxide dismutase (SOD), N-terminal domain
  • 54719 - Fe,Mn superoxide dismutase (SOD), C-terminal domain
  • 0.000000001566Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.000000001911Direct
    57630,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 0.000000001911Direct
    57716,117018
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 0.000000001911Direct
    48150,55811
  • 48150 - DNA-glycosylase
  • 55811 - Nudix
  • 0.000000004172Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.000000005282Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000000009425Direct
    88723,47807
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 0.0000000107Direct
    117018,56091
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0.0000000107Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.00000001144Direct
    53927,53927
  • 53927 - Cytidine deaminase-like
  • 53927 - Cytidine deaminase-like
  • 0.00000001152Direct
    56672,90234
  • 56672 - DNA/RNA polymerases
  • 90234 - Zinc finger domain of DNA polymerase-alpha
  • 0.00000001575Direct
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0.00000001575Direct
    47794,52540
  • 47794 - Rad51 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000002271Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0.00000002909Direct
    53150,48334
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0.00000007194Direct
    46785,51306
  • 46785 - "Winged helix" DNA-binding domain
  • 51306 - LexA/Signal peptidase
  • 0.0000001442Direct
    47781,46929
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0.0000001845Direct
    46934,101238
  • 46934 - UBA-like
  • 101238 - XPC-binding domain
  • 0.0000001845Direct
    52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0.0000001845Direct
    49854,69848
  • 49854 - Spermadhesin, CUB domain
  • 69848 - LCCL domain
  • 0.0000001845Direct
    46565,52833
  • 46565 - Chaperone J-domain
  • 52833 - Thioredoxin-like
  • 0.0000002497Direct
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.0000005667Direct
    52113,142921
  • 52113 - BRCT domain
  • 142921 - WGR domain-like
  • 0.000000588Direct
    81301,81271
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000000588Direct
    56634,52317
  • 56634 - Heme-dependent catalase-like
  • 52317 - Class I glutamine amidotransferase-like
  • 0.000000588Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0.0000008213Direct
    52200,52540
  • 52200 - Toll/Interleukin receptor TIR domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000009693Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.000001153Direct
    49899,56112
  • 49899 - Concanavalin A-like lectins/glucanases
  • 56112 - Protein kinase-like (PK-like)
  • 0.000001704Direct
    47781,52113
  • 47781 - RuvA domain 2-like
  • 52113 - BRCT domain
  • 0.000001785Direct
    53300,56436
  • 53300 - vWA-like
  • 56436 - C-type lectin-like
  • 0.000001785Direct
    49854,56487
  • 49854 - Spermadhesin, CUB domain
  • 56487 - SRCR-like
  • 0.000001785Direct
    56487,49854
  • 56487 - SRCR-like
  • 49854 - Spermadhesin, CUB domain
  • 0.000001785Direct
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.000001846Direct
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000001846Direct
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000001846Direct
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.000002047Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.00000275Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0.000003583Direct
    52540,54752
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54752 - RecA protein, C-terminal domain
  • 0.000004737Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.000004737Direct
    109604,81301
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 0.000007496Direct
    50044,56112
  • 50044 - SH3-domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001088Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.00001119Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.00001403Direct
    101238,46934
  • 101238 - XPC-binding domain
  • 46934 - UBA-like
  • 0.00001403Direct
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.00001923Direct
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.00002295Direct
    100934,100934
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.00002484Direct
    46458,63380
  • 46458 - Globin-like
  • 63380 - Riboflavin synthase domain-like
  • 0.00002484Direct
    81923,52540
  • 81923 - Double Clp-N motif
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00002484Direct
    50249,46785
  • 50249 - Nucleic acid-binding proteins
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0000288Direct
    47781,102712
  • 47781 - RuvA domain 2-like
  • 102712 - JAB1/MPN domain
  • 0.00003155Direct
    54236,46934
  • 54236 - Ubiquitin-like
  • 46934 - UBA-like
  • 0.00003497Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.00003793Direct
    47802,81585
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 0.00007691Direct
    81585,81301
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0.00007691Direct
    51197,53335
  • 51197 - Clavaminate synthase-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.00008503Direct
    51161,48371
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.00009047Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001262Direct
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0.0001435Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0001435Direct
    52540,143517
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 143517 - TRCF domain-like
  • 0.0001627Direct
    52540,141259
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 141259 - CarD-like
  • 0.0001627Direct
    141259,52540
  • 141259 - CarD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001627Direct
    141072,49265
  • 141072 - CalX-like
  • 49265 - Fibronectin type III
  • 0.0001627Direct
    50249,52113
  • 50249 - Nucleic acid-binding proteins
  • 52113 - BRCT domain
  • 0.0001781Direct
    47986,52200
  • 47986 - DEATH domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0001781Direct
    55271,53150
  • 55271 - DNA repair protein MutS, domain I
  • 53150 - DNA repair protein MutS, domain II
  • 0.0001974Direct
    57256,57362
  • 57256 - Elafin-like
  • 57362 - BPTI-like
  • 0.0002539Direct
    54928,51197
  • 54928 - RNA-binding domain, RBD
  • 51197 - Clavaminate synthase-like
  • 0.0002539Direct
    50939,50939
  • 50939 - Sialidases
  • 50939 - Sialidases
  • 0.0002539Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.0003314Direct
    55979,55979
  • 55979 - DNA clamp
  • 55979 - DNA clamp
  • 0.0003579Direct
    52047,56112
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003709Direct
    48371,117839
  • 48371 - ARM repeat
  • 117839 - WWE domain
  • 0.0003709Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0.0003726Direct
    56112,55681
  • 56112 - Protein kinase-like (PK-like)
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0003726Direct
    50370,50370
  • 50370 - Ricin B-like lectins
  • 50370 - Ricin B-like lectins
  • 0.0005866Direct
    48552,48552
  • 48552 - Serum albumin-like
  • 48552 - Serum albumin-like
  • 0.0006703Direct
    63570,56204
  • 63570 - PABC (PABP) domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0006763Direct
    54001,144232
  • 54001 - Cysteine proteinases
  • 144232 - HIT/MYND zinc finger-like
  • 0.0006763Direct
    55846,55846
  • 55846 - N-acetylmuramoyl-L-alanine amidase-like
  • 55846 - N-acetylmuramoyl-L-alanine amidase-like
  • 0.0006763Direct
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0008797Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 1Inherited
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0.1664Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.8339Inherited
    88723,50249
  • 88723 - PIN domain-like
  • 50249 - Nucleic acid-binding proteins
  • 0.02133Inherited
    51182,51182
  • 51182 - RmlC-like cupins
  • 51182 - RmlC-like cupins
  • 0.07321Inherited
    57196,82153
  • 57196 - EGF/Laminin
  • 82153 - FAS1 domain
  • 0.001743Inherited
    56436,82153
  • 56436 - C-type lectin-like
  • 82153 - FAS1 domain
  • 0.02133Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.1027Inherited
    52218,63380
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0.01927Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.2584Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.2885Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.01963Inherited
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 1Inherited
    55874,52172
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 1Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.9949Inherited
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.2406Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.007478Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.008123Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.008431Inherited
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.8118Inherited
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0.8746Inherited
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0.9008Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 1Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 1Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.9849Inherited
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.1865Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.644Inherited
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0.694Inherited
    57016,53955
  • 57016 - Plant lectins/antimicrobial peptides
  • 53955 - Lysozyme-like
  • 0.01591Inherited
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0.459Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2956Inherited
    101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0.05545Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 1Inherited
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.04365Inherited
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.04365Inherited
    82895,57196
  • 82895 - TSP-1 type 1 repeat
  • 57196 - EGF/Laminin
  • 0.3306Inherited
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.459Inherited
    57196,103647
  • 57196 - EGF/Laminin
  • 103647 - TSP type-3 repeat
  • 0.001158Inherited
    49899,58006
  • 49899 - Concanavalin A-like lectins/glucanases
  • 58006 - Assembly domain of cartilage oligomeric matrix protein
  • 0.001158Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.5701Inherited
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1847Inherited
    101690,69065
  • 101690 - PAZ domain
  • 69065 - RNase III domain-like
  • 0.1809Inherited
    57256,57256
  • 57256 - Elafin-like
  • 57256 - Elafin-like
  • 0.005096Inherited
    48371,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1201Inherited
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 0.4857Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1Inherited
    54695,54695
  • 54695 - POZ domain
  • 54695 - POZ domain
  • 0.126Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.9997Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.9664Inherited
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.02293Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.02583Inherited
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0.4694Inherited
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.07521Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.8093Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 1Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.09128Inherited
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.459Inherited
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.5752Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.1402Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.2467Inherited
    48239,49410
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 49410 - Alpha-macroglobulin receptor domain
  • 0.002119Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 1Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.2898Inherited
    50249,116742
  • 50249 - Nucleic acid-binding proteins
  • 116742 - eIF2alpha middle domain-like
  • 0.288Inherited
    116742,110993
  • 116742 - eIF2alpha middle domain-like
  • 110993 - eIF-2-alpha, C-terminal domain
  • 0.288Inherited
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0.005391Inherited
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.2343Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.08492Inherited
    56112,103243
  • 56112 - Protein kinase-like (PK-like)
  • 103243 - KA1-like
  • 0.6321Inherited
    54416,54416
  • 54416 - Amine oxidase N-terminal region
  • 54416 - Amine oxidase N-terminal region
  • 0.008932Inherited
    54416,49998
  • 54416 - Amine oxidase N-terminal region
  • 49998 - Amine oxidase catalytic domain
  • 0.008932Inherited
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0.1027Inherited
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.004277Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1001Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.2242Inherited
    52777,56801
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 0.7552Inherited
    47336,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0.7938Inherited
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 1Inherited
    52172,52172
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0.459Inherited
    56235,52402
  • 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0.08579Inherited
    68923,53795
  • 68923 - PEP carboxykinase N-terminal domain
  • 53795 - PEP carboxykinase-like
  • 0.1571Inherited
    53067,109604
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0.006271Inherited
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.4054Inherited
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.4292Inherited
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.4292Inherited
    52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 0.4292Inherited
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0.004502Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.02214Inherited
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0.1122Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 1Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.6115Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 1Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.1346Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.2467Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 1Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.5929Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.5437Inherited
    81383,49785
  • 81383 - F-box domain
  • 49785 - Galactose-binding domain-like
  • 0.1388Inherited
    81901,81901
  • 81901 - HCP-like
  • 81901 - HCP-like
  • 0.001935Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8823Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.9317Inherited
    48452,57850
  • 48452 - TPR-like
  • 57850 - RING/U-box
  • 0.1012Inherited
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.002165Inherited
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.1027Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 1Inherited
    48050,48056
  • 48050 - Hemocyanin, N-terminal domain
  • 48056 - Di-copper centre-containing domain
  • 0.02891Inherited
    48056,81296
  • 48056 - Di-copper centre-containing domain
  • 81296 - E set domains
  • 0.04845Inherited
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0.09092Inherited
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0.1735Inherited
    55666,46915
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0.01459Inherited
    46915,54211
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01459Inherited
    55666,54791
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.06211Inherited
    54791,50249
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0.06211Inherited
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 1Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 1Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 1Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.002119Inherited
    48350,55550
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0.01176Inherited
    50044,48350
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 0.02746Inherited
    54211,56719
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.06766Inherited
    52833,49785
  • 52833 - Thioredoxin-like
  • 49785 - Galactose-binding domain-like
  • 0.001743Inherited
    81995,56112
  • 81995 - beta-sandwich domain of Sec23/24
  • 56112 - Protein kinase-like (PK-like)
  • 0.003556Inherited
    52833,47933
  • 52833 - Thioredoxin-like
  • 47933 - ERP29 C domain-like
  • 0.01006Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 1Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 1Inherited
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.001624Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.7525Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 1Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 1Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.4933Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.1783Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.4809Inherited
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.01591Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 1Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.4719Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.08708Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.2774Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.2044Inherited
    55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0.5752Inherited
    56801,47336
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 1Inherited
    54695,48403
  • 54695 - POZ domain
  • 48403 - Ankyrin repeat
  • 0.003384Inherited
    64356,58038
  • 64356 - SNARE-like
  • 58038 - SNARE fusion complex
  • 0.6056Inherited
    52540,81271
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 81271 - TGS-like
  • 0.7096Inherited
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.3691Inherited
    50249,57756
  • 50249 - Nucleic acid-binding proteins
  • 57756 - Retrovirus zinc finger-like domains
  • 0.9776Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.2406Inherited
    57288,57288
  • 57288 - Midkine
  • 57288 - Midkine
  • 0.1122Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.07148Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.26Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.06355Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.2731Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.323Inherited
    49503,49785
  • 49503 - Cupredoxins
  • 49785 - Galactose-binding domain-like
  • 0.01149Inherited
    58010,56496
  • 58010 - Fibrinogen coiled-coil and central regions
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.01591Inherited
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0.1966Inherited
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.2123Inherited
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.2123Inherited
    50044,50729
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0.01459Inherited
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.5603Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.05032Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 1Inherited
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.02986Inherited
    57567,57603
  • 57567 - Serine protease inhibitors
  • 57603 - FnI-like domain
  • 0.4716Inherited
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0.6811Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.4034Inherited
    49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0.1457Inherited
    57440,57196
  • 57440 - Kringle-like
  • 57196 - EGF/Laminin
  • 0.003556Inherited
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.1266Inherited
    47874,47874
  • 47874 - Annexin
  • 47874 - Annexin
  • 0.001624Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 1Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00315Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.2401Inherited
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.2082Inherited
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.2343Inherited
    49265,56112
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.3359Inherited
    90229,54928
  • 90229 - CCCH zinc finger
  • 54928 - RNA-binding domain, RBD
  • 0.4716Inherited
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.7476Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.7939Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.8552Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.01433Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0684Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.003767Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0.008358Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.07403Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.01195Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.002555Inherited
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.04365Inherited
    57440,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.07321Inherited
    57603,49265
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.08755Inherited
    49265,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 0.1201Inherited
    48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 0.1377Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 1Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 1Inherited
    49599,54695
  • 49599 - TRAF domain-like
  • 54695 - POZ domain
  • 0.001279Inherited
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 1Inherited
    57850,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 0.6115Inherited
    52172,46689
  • 52172 - CheY-like
  • 46689 - Homeodomain-like
  • 1Inherited
    81296,52540
  • 81296 - E set domains
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001743Inherited
    51101,51101
  • 51101 - Mannose-binding lectins
  • 51101 - Mannose-binding lectins
  • 0.003693Inherited
    52540,48403
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48403 - Ankyrin repeat
  • 0.06269Inherited
    54980,54980
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0.3657Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.4444Inherited
    54928,57756
  • 54928 - RNA-binding domain, RBD
  • 57756 - Retrovirus zinc finger-like domains
  • 0.5663Inherited
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 0.6822Inherited
    88946,88659
  • 88946 - Sigma2 domain of RNA polymerase sigma factors
  • 88659 - Sigma3 and sigma4 domains of RNA polymerase sigma factors
  • 0.3051Inherited
    102860,54197
  • 102860 - mRNA decapping enzyme DcpS N-terminal domain
  • 54197 - HIT-like
  • 0.4716Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.4857Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 1Inherited
    116734,116734
  • 116734 - DNA methylase specificity domain
  • 116734 - DNA methylase specificity domain
  • 0.001743Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.9341Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.008932Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.008932Inherited
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    48452,46565
  • 48452 - TPR-like
  • 46565 - Chaperone J-domain
  • 0.02158Inherited
    54236,54001
  • 54236 - Ubiquitin-like
  • 54001 - Cysteine proteinases
  • 0.001624Inherited
    46565,158702
  • 46565 - Chaperone J-domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.04829Inherited
    49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
  • 0.3388Inherited
    57783,47954
  • 57783 - Zinc beta-ribbon
  • 47954 - Cyclin-like
  • 0.008358Inherited
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0.333Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.02073Inherited
    48113,48113
  • 48113 - Heme-dependent peroxidases
  • 48113 - Heme-dependent peroxidases
  • 0.003556Inherited
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.1809Inherited
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.8672Inherited
    57850,52540
  • 57850 - RING/U-box
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001027Inherited
    52113,52540
  • 52113 - BRCT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.003556Inherited
    50729,48371
  • 50729 - PH domain-like
  • 48371 - ARM repeat
  • 0.06269Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.4827Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 1Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.7075Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.6589Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.01529Inherited
    100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0.01401Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 1Inherited
    46689,46785
  • 46689 - Homeodomain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01506Inherited
    54814,54821
  • 54814 - Prokaryotic type KH domain (KH-domain type II)
  • 54821 - Ribosomal protein S3 C-terminal domain
  • 0.02293Inherited
    81995,49417
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 0.06269Inherited
    52540,54631
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54631 - CBS-domain pair
  • 0.03024Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 1Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 1Inherited
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.09054Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.9584Inherited
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.8694Inherited
    48726,52200
  • 48726 - Immunoglobulin
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.006271Inherited
    55394,55394
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 0.04365Inherited
    56436,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 0.001158Inherited
    56112,48403
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
  • 0.01506Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.02912Inherited
    55797,57546
  • 55797 - PR-1-like
  • 57546 - Crisp domain-like
  • 0.0379Inherited
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.06269Inherited
    48452,49764
  • 48452 - TPR-like
  • 49764 - HSP20-like chaperones
  • 0.1809Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.3627Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.3848Inherited
    52058,52200
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.4004Inherited
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.521Inherited
    52047,52200
  • 52047 - RNI-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.8797Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.5262Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03515Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.0226Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.007766Inherited
    57716,46955
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 46955 - Putative DNA-binding domain
  • 0.007011Inherited
    57884,46689
  • 57884 - Ada DNA repair protein, N-terminal domain (N-Ada 10)
  • 46689 - Homeodomain-like
  • 0.002044Inherited
    49879,56784
  • 49879 - SMAD/FHA domain
  • 56784 - HAD-like
  • 0.01006Inherited
    50809,58022
  • 50809 - XRCC4, N-terminal domain
  • 58022 - XRCC4, C-terminal oligomerization domain
  • 0.06269Inherited
    140383,140383
  • 140383 - BSD domain-like
  • 140383 - BSD domain-like
  • 0.03024Inherited
    50729,140383
  • 50729 - PH domain-like
  • 140383 - BSD domain-like
  • 0.03024Inherited
    46785,158702
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.002463Inherited
    158702,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.007519Inherited
    158702,81296
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0.1388Inherited
    49599,54001
  • 49599 - TRAF domain-like
  • 54001 - Cysteine proteinases
  • 0.2192Inherited
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0.3112Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.9838Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.6408Inherited
    81321,81321
  • 81321 - Family A G protein-coupled receptor-like
  • 81321 - Family A G protein-coupled receptor-like
  • 0.1809Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.333Inherited
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0.4474Inherited
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.6115Inherited
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.7935Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.5262Inherited
    100909,48371
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 48371 - ARM repeat
  • 0.01459Inherited
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.007011Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.4087Inherited
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.6811Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.7114Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7473Inherited
    57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 1Inherited
    81324,51735
  • 81324 - Voltage-gated potassium channels
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    48403,49265
  • 48403 - Ankyrin repeat
  • 49265 - Fibronectin type III
  • 0.003556Inherited
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0.007011Inherited
    48452,48403
  • 48452 - TPR-like
  • 48403 - Ankyrin repeat
  • 0.00111Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 1Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.01475Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.02491Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.003767Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    57535,49899,90188
  • 57535 - Complement control module/SCR domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 90188 - Somatomedin B domain
  • 0Direct
    50249,57756,57756
  • 50249 - Nucleic acid-binding proteins
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    57440,81901,81901
  • 57440 - Kringle-like
  • 81901 - HCP-like
  • 81901 - HCP-like
  • 0Direct
    52113,56672,100879
  • 52113 - BRCT domain
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    50370,56436,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    57535,57535,49899
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    81624,46946,57716
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    55550,50044,50729
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0Direct
    58006,57196,57196
  • 58006 - Assembly domain of cartilage oligomeric matrix protein
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,103647
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 103647 - TSP type-3 repeat
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    58113,58113,58113
  • 58113 - Apolipoprotein A-I
  • 58113 - Apolipoprotein A-I
  • 58113 - Apolipoprotein A-I
  • 0Direct
    52540,49899,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    49899,58006,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 58006 - Assembly domain of cartilage oligomeric matrix protein
  • 57196 - EGF/Laminin
  • 0Direct
    47473,51695,55550
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 0Direct
    46785,57903,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    49854,69848,49785
  • 49854 - Spermadhesin, CUB domain
  • 69848 - LCCL domain
  • 49785 - Galactose-binding domain-like
  • 0Direct
    54236,46934,101238
  • 54236 - Ubiquitin-like
  • 46934 - UBA-like
  • 101238 - XPC-binding domain
  • 0Direct
    50249,52113,52113
  • 50249 - Nucleic acid-binding proteins
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    56512,52218,63380
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    81995,49417,81296
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    51695,55550,55550
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    57716,117018,56091
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0.000000001911Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000000005282Direct
    117018,56091,50249
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0.0000000107Direct
    53098,56672,90234
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 90234 - Zinc finger domain of DNA polymerase-alpha
  • 0.00000001575Direct
    53150,48334,52540
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000007194Direct
    52200,52540,46785
  • 52200 - Toll/Interleukin receptor TIR domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00000009647Direct
    52113,142921,47587
  • 52113 - BRCT domain
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.0000001396Direct
    46565,52833,52833
  • 46565 - Chaperone J-domain
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.0000001845Direct
    52540,52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0.0000001845Direct
    50249,47781,46929
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0.0000001845Direct
    57630,57196,50494
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0.000000208Direct
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.0000002166Direct
    109604,81301,81271
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000000588Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000007Direct
    49854,56487,49854
  • 49854 - Spermadhesin, CUB domain
  • 56487 - SRCR-like
  • 49854 - Spermadhesin, CUB domain
  • 0.000001785Direct
    48452,48452,48403
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48403 - Ankyrin repeat
  • 0.000001785Direct
    50249,47781,52113
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 52113 - BRCT domain
  • 0.000001785Direct
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.000001846Direct
    57196,57196,50494
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0.000001846Direct
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.000001846Direct
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.000001846Direct
    56091,50249,47781
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0.000004615Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0.000004615Direct
    81923,52540,52540
  • 81923 - Double Clp-N motif
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00001403Direct
    57630,57440,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00001715Direct
    56436,56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.00001923Direct
    52113,52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00002227Direct
    46458,63380,52343
  • 46458 - Globin-like
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.00002484Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.00004044Direct
    81901,81901,81901
  • 81901 - HCP-like
  • 81901 - HCP-like
  • 81901 - HCP-like
  • 0.00004204Direct
    47802,81585,81301
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0.00007691Direct
    54928,51197,53335
  • 54928 - RNA-binding domain, RBD
  • 51197 - Clavaminate synthase-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.00008503Direct
    46785,46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00008503Direct
    53448,51161,48371
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.00009047Direct
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0001203Direct
    46934,101238,46934
  • 46934 - UBA-like
  • 101238 - XPC-binding domain
  • 46934 - UBA-like
  • 0.0001627Direct
    52540,141259,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 141259 - CarD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001627Direct
    52540,52540,143517
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 143517 - TRCF domain-like
  • 0.0001627Direct
    55271,53150,48334
  • 55271 - DNA repair protein MutS, domain I
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0.0001627Direct
    141259,52540,52540
  • 141259 - CarD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001627Direct
    56487,49854,56487
  • 56487 - SRCR-like
  • 49854 - Spermadhesin, CUB domain
  • 56487 - SRCR-like
  • 0.0001627Direct
    81296,52540,48403
  • 81296 - E set domains
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48403 - Ankyrin repeat
  • 0.0001627Direct
    52540,52540,141259
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 141259 - CarD-like
  • 0.0001627Direct
    56091,50249,52113
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 52113 - BRCT domain
  • 0.0001781Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.0002918Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0007985Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.06269Inherited
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.06269Inherited
    57196,82153,82153
  • 57196 - EGF/Laminin
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.001743Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.1027Inherited
    47384,55874,52172
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 1Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.007478Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.01098Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.9158Inherited
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0.7911Inherited
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0.8118Inherited
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.8118Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    64268,50044,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.4716Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.338Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 1Inherited
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.04365Inherited
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.04365Inherited
    57603,82895,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.3306Inherited
    82895,82895,57196
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 57196 - EGF/Laminin
  • 0.3306Inherited
    57196,103647,103647
  • 57196 - EGF/Laminin
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.001158Inherited
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1847Inherited
    48371,52540,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1201Inherited
    47031,50729,55550
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.6278Inherited
    47986,47986,52540
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1266Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.8823Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.9545Inherited
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.4857Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.914Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.001978Inherited
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.459Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.1346Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.1847Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.1866Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.5619Inherited
    50249,116742,110993
  • 50249 - Nucleic acid-binding proteins
  • 116742 - eIF2alpha middle domain-like
  • 110993 - eIF-2-alpha, C-terminal domain
  • 0.288Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.08492Inherited
    54416,54416,49998
  • 54416 - Amine oxidase N-terminal region
  • 54416 - Amine oxidase N-terminal region
  • 49998 - Amine oxidase catalytic domain
  • 0.008932Inherited
    48552,48552,48552
  • 48552 - Serum albumin-like
  • 48552 - Serum albumin-like
  • 48552 - Serum albumin-like
  • 0.001253Inherited
    52777,56801,47336
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 0.6196Inherited
    52777,52777,56801
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 0.6521Inherited
    56801,47336,52777
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0.7253Inherited
    47336,52777,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.7813Inherited
    53067,53067,109604
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0.006271Inherited
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.4054Inherited
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.4054Inherited
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.4292Inherited
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.4292Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.7182Inherited
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.9085Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.1346Inherited
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0.182Inherited
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.7684Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8198Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8823Inherited
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.1027Inherited
    48050,48056,81296
  • 48050 - Hemocyanin, N-terminal domain
  • 48056 - Di-copper centre-containing domain
  • 81296 - E set domains
  • 0.02891Inherited
    51905,51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.05545Inherited
    46915,54211,55666
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0.01459Inherited
    54211,55666,46915
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0.01459Inherited
    55666,46915,54211
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01459Inherited
    55666,54791,50249
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0.06211Inherited
    54211,55666,54791
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.06211Inherited
    50044,48350,55550
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0.01176Inherited
    55874,54211,56719
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.05443Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 1Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7525Inherited
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.7935Inherited
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.01591Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.9776Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.3236Inherited
    55008,55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0.337Inherited
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0226Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1031Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.2731Inherited
    49503,49785,49785
  • 49503 - Cupredoxins
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.01973Inherited
    49503,49503,49785
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49785 - Galactose-binding domain-like
  • 0.004277Inherited
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.1966Inherited
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.2123Inherited
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.337Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.3359Inherited
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.02986Inherited
    47473,57889,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.1809Inherited
    47473,47473,57889
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0.1809Inherited
    50044,55550,50044
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.6278Inherited
    50729,57889,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.8051Inherited
    53300,53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.337Inherited
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.001253Inherited
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.1266Inherited
    48726,49265,56112
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.2343Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.2421Inherited
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.002044Inherited
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.2082Inherited
    75399,75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.2082Inherited
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.2343Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.8422Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.8552Inherited
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.7178Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.9031Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.929Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.6851Inherited
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.008358Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.07403Inherited
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.6321Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.002555Inherited
    57440,57440,57603
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.07321Inherited
    57440,57603,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.07321Inherited
    57603,57603,57440
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.07321Inherited
    57603,57603,49265
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.07321Inherited
    49265,57603,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.1201Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    54534,54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.1809Inherited
    54534,54534,48452
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.3306Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.008932Inherited
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.9507Inherited
    52113,52540,48019
  • 52113 - BRCT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.003556Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 1Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.8072Inherited
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0.01401Inherited
    55874,52172,52172
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0.1809Inherited
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.007011Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 1Inherited
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.09054Inherited
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.09054Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.03515Inherited
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.8694Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0226Inherited
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.06269Inherited
    48239,49410,50242
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.1444Inherited
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.2468Inherited
    52058,52058,52200
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.6551Inherited
    52058,52047,52200
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.8051Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03515Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05391Inherited
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.399Inherited
    49879,56784,52540
  • 49879 - SMAD/FHA domain
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.006271Inherited
    50729,140383,140383
  • 50729 - PH domain-like
  • 140383 - BSD domain-like
  • 140383 - BSD domain-like
  • 0.03024Inherited
    52540,46785,158702
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.001935Inherited
    46785,158702,52540
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002555Inherited
    158702,52540,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.007519Inherited
    46785,158702,81296
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0.01496Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.4057Inherited
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.2406Inherited
    57535,57535,50494
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0.459Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.6811Inherited
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.7182Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.4087Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.5066Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5066Inherited
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.6811Inherited


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