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Biological Process (BP): organelle organization

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + 2:   cellular component organization or biogenesis [GO:0071840] <2>(123|122) (647|619|358)
+ + 2:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ 1:   cellular component organization [GO:0016043] <33>(113|104) (617|594|349)
0:   organelle organization [GO:0006996] <27>(69|66) (402|354|191)
- 1:   single-organism organelle organization [GO:1902589] <35>(31|30) (192|170|100)
- 1:   organelle assembly [GO:0070925] <30>(18|18) (121|79|51)
- 1:   chromosome organization [GO:0051276] <20>(14|15) (152|119|56)
- 1:   mitochondrion organization [GO:0007005] <15>(15|11) (82|37|15)
- 1:   nucleus organization [GO:0006997] <15>(3|3) (32|11|4)
- 1:   vesicle organization [GO:0016050] <13>(5|4) (48|30|13)
- 1:   plastid organization [GO:0009657] <11>(0|0) (11|4|0)
- 1:   cytoskeleton organization [GO:0007010] <10>(25|24) (145|138|83)
- 1:   peroxisome organization [GO:0007031] <8>(2|2) (9|2|0)
- 1:   endoplasmic reticulum organization [GO:0007029] <7>(1|1) (12|7|5)
- 1:   organelle inheritance [GO:0048308] <7>(1|1) (5|3|1)
- 1:   vacuole organization [GO:0007033] <7>(7|5) (32|16|3)
- 1:   organelle fusion [GO:0048284] <6>(4|5) (19|6|2)
- 1:   Golgi organization [GO:0007030] <5>(1|2) (24|19|7)
- 1:   organelle fission [GO:0048285] <5>(9|11) (69|37|9)
- 1:   phagosome maturation [GO:0090382] <4>(1|1) (4|4|1)
- 1:   fusome organization [GO:0045478] <3>(0|0) (1|0|0)
- 1:   P granule organization [GO:0030719] <2>(1|1) (2|0|0)
- 1:   lipid particle organization [GO:0034389] <2>(0|0) (4|1|0)
- 1:   postsynaptic specialization organization [GO:0099084] <2>(0|0) (6|2|1)
- 1:   rhabdomere development [GO:0042052] <2>(0|0) (10|4|1)
- 1:   ER body organization [GO:0080119](0|0) (0|0|0)
- 1:   endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111](0|0) (1|0|0)
- 1:   gas vesicle organization [GO:0031412](0|0) (0|0|0)
- 1:   multi-organism organelle organization [GO:1902590](0|0) (0|0|0)
- 1:   spectrosome organization [GO:0030721](0|0) (2|0|0)
- 1:   subsynaptic reticulum organization [GO:1990255](0|0) (4|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 16 kDa subunit ARPC50.000000025780.000001806Direct
Arp2/3 complex 21 kDa subunit ARPC30.00000094710.00005607Direct
Bcl-2 inhibitors of programmed cell death00Direct
Chromo domain-like0.0000076760Direct
Core binding factor beta, CBF0.000000055440.00000000682Direct
DNA topoisomerase IV, alpha subunit0.000032920.000000009321Direct
EF-hand0.00067180.0000000007702Direct
Histone-fold0.00000000000025170Direct
HMG-box0.000087940Direct
P-loop containing nucleoside triphosphate hydrolases0.000000000056360Direct
RNase A-like0.00000000017310.00007891Direct
The spindle assembly checkpoint protein mad20.0000016560Direct
Tim10-like00Direct
Tropomyosin0.000000090490.000001125Direct
Tudor/PWWP/MBT0.000088130.0000000005579Direct
SNARE fusion complex0.33230.001746Inherited
Mss4-like0.062740.116Inherited
WD40 repeat-like0.10190Inherited
Arp2/3 complex subunits0.00000097630.02284Inherited
Profilin (actin-binding protein)0.13750.1025Inherited
Actin depolymerizing proteins0.0067140.000000003258Inherited
BAR/IMD domain-like0.058841Inherited
UBC-like0.0095970.001161Inherited
Protein kinase-like (PK-like)0.065110.2092Inherited
SRF-like0.00018680.001072Inherited
Translational machinery components0.0045610.272Inherited
Lipocalins11Inherited
Ubiquitin-like0.085340.0001916Inherited
Cu,Zn superoxide dismutase-like0.042880.1345Inherited
Metallothionein0.0048410.1156Inherited
NAP-like0.021630.00001207Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.86320.4866Inherited
Arginase/deacetylase0.014650.000000000000005563Inherited
Ribosomal proteins L15p and L18e0.024670.1408Inherited
Ribosomal protein S80.00070150.01401Inherited
Ribosomal proteins S24e, L23 and L15e0.0084250.02832Inherited
RL5-like0.00026750.009578Inherited
Translation proteins SH3-like domain0.000010360.008895Inherited
Zn-binding ribosomal proteins0.0027770.000597Inherited
ARM repeat0.80840.0000000000006581Inherited
Acyl-CoA N-acyltransferases (Nat)0.0047970.000000004203Inherited
HydA/Nqo6-like0.000093890.0114Inherited
RNI-like0.048781Inherited
Cytochrome c oxidase subunit h0.28950.3391Inherited
Cysteine alpha-hairpin motif0.044190.07276Inherited
Thioredoxin-like11Inherited
Nucleic acid-binding proteins0.0084910.000000000005804Inherited
Annexin0.44421Inherited
Aquaporin-like11Inherited
Bet v1-like0.85491Inherited
Phospholipase D/nuclease0.00000000024330.001495Inherited
Troponin coil-coiled subunits0.092230Inherited
SET domain0.076640Inherited
TPR-like0.35930Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.0075150.3602Inherited
MFS general substrate transporter11Inherited
alpha/beta-Hydrolases11Inherited
Sec1/munc18-like (SM) proteins0.072620.04991Inherited
Inhibitor of apoptosis (IAP) repeat0.0000000087440.1063Inherited
Immunoglobulin0.30041Inherited
Interleukin 8-like chemokines0.13750.2135Inherited
Prefoldin10.9033Inherited
Stathmin0.14481Inherited
Subunits of heterodimeric actin filament capping protein Capz0.42020.4097Inherited
Mitochondrial carrier0.00046520.1753Inherited
HAD-like0.83131Inherited
LexA/Signal peptidase0.00042540.4568Inherited
Chaperone J-domain0.018860.557Inherited
Ribonuclease H-like0.91560.1687Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
AD-003 protein-like0.000000000047770.000000009241Direct
Arginine methyltransferase0.000000061970.00000000000001031Direct
Arp2/3 complex 16 kDa subunit ARPC50.000000046480.000002148Direct
Arp2/3 complex 21 kDa subunit ARPC30.0000016820.00006599Direct
Bcl-2 inhibitors of programmed cell death00Direct
C5 cytosine-specific DNA methylase, DCM0.00023480.000001671Direct
Chromo domain0.0000094880.000000000376Direct
Core binding factor beta, CBF0.000000099170.000000009241Direct
DNA topoisomerase IV, alpha subunit0.000041090.00000001214Direct
G proteins00Direct
Histone deacetylase, HDAC0.00016220Direct
HMG-box0.00010790Direct
Mitochondrial ribosomal protein L51/S25/CI-B8 domain0.000021390.0009758Direct
Nuclease0.000000000027340.0000001086Direct
Nucleosome core histones00Direct
Ribonuclease A-like0.00000000072350.00004419Direct
Ribosomal protein S27e0.000021010.000355Direct
SelR domain0.000000006550.000003613Direct
The spindle assembly checkpoint protein mad20.0000031780Direct
Thioesterases0.0000083340.000402Direct
Tim10/DDP00Direct
Tropomyosin0.00000045850.0000007361Direct
Motor proteins0.064370.000000000006808Inherited
SNARE fusion complex0.28530.0008506Inherited
WD40-repeat0.17080Inherited
Arp2/3 complex subunits0.0000014540.01576Inherited
Profilin (actin-binding protein)0.10940.07087Inherited
Cofilin-like0.0046070.002816Inherited
UBC-related0.0068450.000002838Inherited
Protein kinases, catalytic subunit0.052210.2971Inherited
SRF-like0.00011050.001792Inherited
Ribosomal protein L18 and S110.0065040.007794Inherited
Rps19E-like0.000053120.001234Inherited
Translational machinery components0.0041550.0007032Inherited
Retinol binding protein-like11Inherited
Cu,Zn superoxide dismutase-like0.03350.09906Inherited
Metallothionein0.0069650.1313Inherited
NAP-like0.026710.00001981Inherited
TBP-associated factors, TAFs0.047930.01408Inherited
Penta-EF-hand proteins0.0041550.0007883Inherited
L30e/L7ae ribosomal proteins0.077250.141Inherited
Ribosomal proteins L15p and L18e0.030390.152Inherited
Ribosomal protein L50.00039530.01044Inherited
Ribosomal protein S80.0010330.01525Inherited
Cold shock DNA-binding domain-like0.073640.9194Inherited
N-acetyl transferase, NAT0.054680.0000000000001769Inherited
Nq06-like0.000065320.002367Inherited
RecA protein-like (ATPase-domain)0.011580.00004072Inherited
Annexin0.38311Inherited
Aquaporin-like0.97761Inherited
Calmodulin-like0.047130.5967Inherited
Troponin I0.11090.2216Inherited
Tetratricopeptide repeat (TPR)0.18640.0000000000003617Inherited
Sec1/munc18-like (SM) proteins0.056610.03338Inherited
GABARAP-like0.077250.08878Inherited
Inhibitor of apoptosis (IAP) repeat0.000000018760.07813Inherited
p25-alpha0.0011710.001398Inherited
Capz beta-1 subunit0.073640.08441Inherited
Interleukin 8-like chemokines0.10940.1498Inherited
Prefoldin0.92790.7032Inherited
Stathmin0.12270.9374Inherited
Mitochondrial carrier0.0023110.2506Inherited
14-3-3 protein0.60140.7713Inherited
DJ-1/PfpI0.094110.4422Inherited
Extended AAA-ATPase domain0.11370.000000000000005999Inherited
NLI interacting factor-like phosphatase0.0065980.00001381Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
P-loop containing nucleoside triphosphate hydrolases0Direct
Troponin coil-coiled subunits0Direct
Histone-fold0Direct
DNA repair protein MutS, domain III0Direct
WD40 repeat-like0Direct
Pseudo ankyrin repeat-like0Direct
FYVE/PHD zinc finger0Direct
TPR-like0Direct
SET domain0Direct
Domain of early E2A DNA-binding protein, ADDBP0Direct
Polo-box domain0Direct
Calponin-homology domain, CH-domain0Direct
Chromo domain-like0Direct
The spindle assembly checkpoint protein mad20Direct
Tim10-like0Direct
HMG-box0Direct
Bcl-2 inhibitors of programmed cell death0Direct
Zn-binding domains of ADDBP0Direct
Bromodomain0Direct
Intermediate filament protein, coiled coil region0Direct
Clavaminate synthase-like9.676e-16Direct
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment0.000000000000001898Direct
Arginase/deacetylase0.000000000000002832Direct
Prokaryotic type I DNA topoisomerase0.00000000000001446Direct
RuBisCo LSMT C-terminal, substrate-binding domain0.00000000000002928Direct
ARM repeat0.0000000000003566Direct
Nucleic acid-binding proteins0.000000000003237Direct
Eferin C-derminal domain-like0.000000000009754Direct
Formin homology 2 domain (FH2 domain)0.0000000002864Direct
Tudor/PWWP/MBT0.000000000325Direct
GAS2 domain-like0.0000000003673Direct
EF-hand0.0000000004508Direct
RING/U-box0.0000000006132Direct
LEM domain0.00000000127Direct
Actin depolymerizing proteins0.00000000194Direct
Acyl-CoA N-acyltransferases (Nat)0.000000002512Direct
Core binding factor beta, CBF0.000000004105Direct
HAND domain of the nucleosome remodeling ATPase ISWI0.000000005036Direct
Kix domain of CBP (creb binding protein)0.000000005234Direct
DNA topoisomerase IV, alpha subunit0.000000005635Direct
DNA repair protein MutS, domain I0.000000007039Direct
ARID-like0.000000009922Direct
BRCT domain0.00000001013Direct
Type II DNA topoisomerase0.00000001099Direct
Eukaryotic DNA topoisomerase I, dispensable insert domain0.00000001879Direct
C-terminal, gelsolin-like domain of Sec23/240.00000002661Direct
Smc hinge domain0.00000003818Direct
Actin-crosslinking proteins0.0000000732Direct
Hypothetical protein AF0491, middle domain0.00000007878Direct
TAZ domain0.0000001749Direct
Cap-Gly domain0.0000002587Direct
DNA breaking-rejoining enzymes0.000000404Direct
DNA repair protein MutS, domain II0.0000004362Direct
Mitochondrial import receptor subunit Tom200.0000006184Direct
Tropomyosin0.0000007207Direct
CCHHC domain0.0000009597Direct
p53 tetramerization domain0.000001035Direct
Arp2/3 complex 16 kDa subunit ARPC50.000001165Direct
Spectrin repeat0.000001249Direct
DNA mismatch repair protein MutL0.000003668Direct
Ribosomal protein S5 domain 2-like0.000004361Direct
MAST3 pre-PK domain-like0.000006335Direct
NAP-like0.000007996Direct
Taf5 N-terminal domain-like0.000008557Direct
DHS-like NAD/FAD-binding domain0.00001283Direct
Sec7 domain0.0000139Direct
Outer arm dynein light chain 10.00001745Direct
FYSH domain0.00001916Direct
RuvA domain 2-like0.00003139Direct
C-terminal autoproteolytic domain of nucleoporin nup980.00003384Direct
Translation initiation factor IF3, N-terminal domain0.00003746Direct
Peptidylarginine deiminase Pad4, middle domain0.00003795Direct
Arp2/3 complex 21 kDa subunit ARPC30.00003795Direct
GyrA/ParC C-terminal domain-like0.00003795Direct
ORC1-binding domain0.00005092Direct
G protein-binding domain0.00005374Direct
RNase A-like0.00005374Direct
SPOC domain-like0.00005374Direct
Telomeric repeat binding factor (TRF) dimerisation domain0.00005754Direct
DNA primase core0.00007411Direct
Plakin repeat0.0000865Direct
SAP domain0.0000865Direct
Cysteine proteinases0.0001083Direct
Prokaryotic type KH domain (KH-domain type II)0.000124Direct
Ubiquitin-like0.0001324Direct
Calpain large subunit, middle domain (domain III)0.0001356Direct
Translation initiation factor IF3, C-terminal domain0.0001445Direct
Rad50 coiled-coil Zn hook0.0001465Direct
EF-G C-terminal domain-like0.0001563Direct
MIT domain0.0001649Direct
Helical domain of Sec23/240.0003287Direct
Rps17e-like0.0003599Direct
Zn-binding ribosomal proteins0.0004208Direct
Rad51 N-terminal domain-like0.0004359Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.0005337Direct
Myosin rod fragments0.000554Direct
t-snare proteins0.0006135Direct
JAB1/MPN domain0.0007039Direct
SRF-like0.0007644Direct
UBC-like0.0008293Direct
Nucleoplasmin-like core domain0.0008804Direct
BRCA2 helical domain0.0008891Direct
BRCA2 tower domain0.0008891Direct
EB1 dimerisation domain-like0.0009245Direct
Nuclear receptor coactivator interlocking domain0.0009343Direct
Translation proteins0.2253Inherited
Ribosome recycling factor, RRF0.1402Inherited
Kinetochore globular domain0.001192Inherited
Leucine zipper domain1Inherited
14-3-3 protein0.7701Inherited
E2F-DP heterodimerization region0.3352Inherited
Thiolase-like1Inherited
Multidrug resistance efflux transporter EmrE1Inherited
Mitochondrial carrier0.1416Inherited
p53-like transcription factors0.5822Inherited
Metallothionein0.09207Inherited
Concanavalin A-like lectins/glucanases1Inherited
BAR/IMD domain-like1Inherited
Sec1/munc18-like (SM) proteins0.03869Inherited
Zn-finger domain of Sec23/240.0012Inherited
beta-sandwich domain of Sec23/240.05223Inherited
vWA-like1Inherited
Cullin homology domain0.158Inherited
Functional domain of the splicing factor Prp180.02441Inherited
Kelch motif0.5474Inherited
POZ domain0.7526Inherited
Cullin repeat-like0.5396Inherited
CRAL/TRIO domain0.2712Inherited
CRAL/TRIO N-terminal domain0.08501Inherited
WW domain1Inherited
Class II aaRS and biotin synthetases1Inherited
HRDC-like0.04203Inherited
Nitrite/Sulfite reductase N-terminal domain-like0.02708Inherited
Nitrite and sulphite reductase 4Fe-4S domain-like0.06772Inherited
IHF-like DNA-binding proteins0.3253Inherited
Zinc beta-ribbon0.5413Inherited
Translation proteins SH3-like domain0.006587Inherited
Ribosomal protein S80.01049Inherited
Ribosomal protein L29 (L29p)0.01743Inherited
Ribosomal proteins S24e, L23 and L15e0.02164Inherited
Ribosomal protein S3 C-terminal domain0.0398Inherited
Ribosomal protein L11, C-terminal domain0.04233Inherited
Ribosomal L11/L12e N-terminal domain0.04233Inherited
Ribosomal protein L30p/L7e0.07446Inherited
Ribosomal protein L60.078Inherited
Ribosomal protein L16p/L10e0.1005Inherited
Ribosomal protein L10-like0.1206Inherited
Ribosomal protein L10.1418Inherited
Translational machinery components0.224Inherited
Endosomal sorting complex assembly domain0.01382Inherited
Ribosomal protein S20.02441Inherited
RL5-like0.007101Inherited
L30e-like0.2798Inherited
Ribosomal protein L40.3253Inherited
Single hybrid motif1Inherited
Ribonuclease PH domain 2-like1Inherited
CoA-dependent acyltransferases1Inherited
E set domains1Inherited
Geminin coiled-coil domain0.04082Inherited
Notch domain0.4992Inherited
Anthrax protective antigen0.05209Inherited
Rhodanese/Cell cycle control phosphatase0.5618Inherited
Growth factor receptor domain1Inherited
HSP20-like chaperones0.5202Inherited
Ricin B-like lectins0.9903Inherited
Cu,Zn superoxide dismutase-like0.1076Inherited
F1F0 ATP synthase subunit C0.003336Inherited
Metallo-dependent hydrolases1Inherited
Composite domain of metallo-dependent hydrolases0.8223Inherited
DNA-binding domain0.003609Inherited
RmlC-like cupins1Inherited
PDZ domain-like1Inherited
SMAD/FHA domain0.03826Inherited
Fibronectin type III1Inherited
XPC-binding domain0.01428Inherited
Clc chloride channel0.3272Inherited
CBS-domain pair1Inherited
Hypothetical protein c14orf129, hspc2100.003873Inherited
Phoshotransferase/anion transport protein0.9975Inherited
Cyclophilin-like1Inherited
Prefoldin0.8051Inherited
DPP6 N-terminal domain-like0.9132Inherited
HCP-like0.6187Inherited
DNase I-like1Inherited
Transducin (alpha subunit), insertion domain0.5329Inherited
EGF/Laminin1Inherited
L domain-like1Inherited
Ribosomal protein S190.002902Inherited
Ribosomal protein L19 (L19e)0.002952Inherited
Mitochondrial glycoprotein MAM33-like0.003584Inherited
RplX-like0.007714Inherited
Ribosomal protein L31e0.007714Inherited
Ribosomal proteins L15p and L18e0.1129Inherited
Ribosomal protein L130.1203Inherited
S15/NS1 RNA-binding domain0.7086Inherited
Class I glutamine amidotransferase-like1Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Myosin S1 fragment, N-terminal domain0.001806Inherited
Cupredoxins1Inherited
MFS general substrate transporter1Inherited
Tricorn protease domain 20.007128Inherited
HR1 repeat1Inherited
Second domain of FERM0.662Inherited
PAZ domain0.3537Inherited
Ribonuclease H-like0.1361Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.8335Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.9244Inherited
Actin-like ATPase domain0.7173Inherited
SWIB/MDM2 domain0.06178Inherited
Creatinase/aminopeptidase1Inherited
FAD-linked reductases, C-terminal domain1Inherited
PRC-barrel domain0.001535Inherited
CAD & PB1 domains0.6883Inherited
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0.01256Inherited
SH2 domain1Inherited
PH domain-like1Inherited
Sm-like ribonucleoproteins1Inherited
BEACH domain0.3911Inherited
Clathrin adaptor appendage domain0.9132Inherited
Serpins1Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.4132Inherited
ACP-like1Inherited
Terpenoid synthases1Inherited
FAD/NAD(P)-binding domain1Inherited
4Fe-4S ferredoxins0.6502Inherited
RNI-like1Inherited
Cysteine alpha-hairpin motif0.05708Inherited
Cytochrome c oxidase subunit h0.2825Inherited
HydA/Nqo6-like0.008493Inherited
Thioredoxin-like1Inherited
Initiation factor IF2/eIF5b, domain 30.03514Inherited
eIF1-like0.2158Inherited
PKD domain0.08436Inherited
Di-copper centre-containing domain0.4295Inherited
Domain of poly(ADP-ribose) polymerase0.01624Inherited
C-terminal domain of Ku800.04233Inherited
SAND domain-like0.8417Inherited
WGR domain-like0.1533Inherited
DNA clamp0.2476Inherited
5' to 3' exonuclease, C-terminal subdomain0.42Inherited
ADP-ribosylation0.785Inherited
PIN domain-like1Inherited
Metallo-hydrolase/oxidoreductase1Inherited
Homeodomain-like0.9144Inherited
Regulator of G-protein signaling, RGS0.597Inherited
Annexin1Inherited
Galactose oxidase, central domain0.6045Inherited
Galactose-binding domain-like1Inherited
Calcium ATPase, transduction domain A1Inherited
Calcium ATPase, transmembrane domain M1Inherited
Zn2/Cys6 DNA-binding domain1Inherited
ASF1-like0.03583Inherited
Tex N-terminal region-like0.021Inherited
Eukaryotic type KH-domain (KH-domain type I)0.9569Inherited
"Winged helix" DNA-binding domain0.0133Inherited
FKBP-like1Inherited
Pentein0.05997Inherited
Metallo-dependent phosphatases1Inherited
Hook domain0.002348Inherited
Stathmin0.9193Inherited
Cytokine1Inherited
Lamin A/C globular tail domain0.0122Inherited
Immunoglobulin1Inherited
Plexin repeat1Inherited
CalX-like0.6591Inherited
Integrin beta tail domain1Inherited
Integrin domains1Inherited
A middle domain of Talin 10.002675Inherited
alpha-catenin/vinculin-like0.3188Inherited
Aquaporin-like1Inherited
FF domain0.08997Inherited
Bet v1-like1Inherited
ENTH/VHS domain0.1764Inherited
L27 domain1Inherited
Snake toxin-like1Inherited
Family A G protein-coupled receptor-like1Inherited
Voltage-gated potassium channels1Inherited
VHP, Villin headpiece domain0.06723Inherited
Nitrous oxide reductase, N-terminal domain0.06631Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.002875Inherited
Mss4-like0.09234Inherited
Profilin (actin-binding protein)0.0813Inherited
I/LWEQ domain0.05687Inherited
GTPase activation domain, GAP0.8709Inherited
SH3-domain1Inherited
TRAF domain-like1Inherited
PAH2 domain0.9693Inherited
PYP-like sensor domain (PAS domain)1Inherited
PUA domain-like0.006712Inherited
Uracil-DNA glycosylase-like0.5487Inherited
Nucleoporin domain0.001703Inherited
EPT/RTPC-like0.3429Inherited
KA1-like0.1725Inherited
GAT-like domain0.4151Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.119Inherited
VPS9 domain1Inherited
beta-beta-alpha zinc fingers1Inherited
Retrovirus capsid dimerization domain-like0.1977Inherited
Double Clp-N motif0.3934Inherited
ACT-like1Inherited
ClpP/crotonase1Inherited
Release factor1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
Formate dehydrogenase/DMSO reductase, domains 1-30.03618Inherited
2Fe-2S ferredoxin-like0.9664Inherited
Gamma-glutamyl cyclotransferase-like0.7896Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.008068Inherited
C-terminal domain of adenylylcyclase associated protein0.03583Inherited
SAICAR synthase-like0.1929Inherited
RNA-binding domain, RBD1Inherited
alpha/beta-Hydrolases1Inherited
post-AAA+ oligomerization domain-like0.003056Inherited
Tubulin nucleotide-binding domain-like0.04746Inherited
Tubulin C-terminal domain-like0.1957Inherited
Inhibitor of apoptosis (IAP) repeat0.08436Inherited
Quinoprotein alcohol dehydrogenase-like0.03032Inherited
Ran binding protein zinc finger-like0.2106Inherited
SAM/Pointed domain1Inherited
Glycosyl hydrolase domain1Inherited
Subtilisin-like1Inherited
Protease propeptides/inhibitors1Inherited
PX domain0.2141Inherited
Supernatant protein factor (SPF), C-terminal domain0.07269Inherited
Phospholipase D/nuclease0.001072Inherited
Galactose mutarotase-like1Inherited
Ypt/Rab-GAP domain of gyp1p0.7792Inherited
DBL homology domain (DH-domain)0.9566Inherited
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0.01116Inherited
Protein kinase-like (PK-like)0.1702Inherited
Cysteine-rich domain1Inherited
Hect, E3 ligase catalytic domain0.7418Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
PapD-like0.7436Inherited
FAT domain of focal adhesion kinase0.3614Inherited
Cadherin-like1Inherited
DEATH domain1Inherited
Moesin tail domain0.07868Inherited
Arp2/3 complex subunits0.01734Inherited
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.02234Inherited
RUN domain-like0.1792Inherited
Interleukin 8-like chemokines0.1738Inherited
Subunits of heterodimeric actin filament capping protein Capz0.3447Inherited
RGC domain-like0.4433Inherited
Rap/Ran-GAP0.9132Inherited
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30.05886Inherited
Lipocalins1Inherited
Band 7/SPFH domain0.4107Inherited
FtsH protease domain-like0.05994Inherited
DnaJ/Hsp40 cysteine-rich domain0.1792Inherited
C-type lectin-like1Inherited
HAD-like1Inherited
Invasin/intimin cell-adhesion fragments0.1795Inherited
SNARE-like0.01074Inherited
SNARE fusion complex0.001255Inherited
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.03583Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.3009Inherited
LuxS/MPP-like metallohydrolase0.09395Inherited
LexA/Signal peptidase0.3864Inherited
Fzo-like conserved region0.002675Inherited
GroEL equatorial domain-like0.5822Inherited
Head domain of nucleotide exchange factor GrpE0.07343Inherited
Coiled-coil domain of nucleotide exchange factor GrpE0.07343Inherited
GST C-terminal domain-like1Inherited
GroEL apical domain-like0.2903Inherited
GAF domain-like0.6682Inherited
GroEL-intermediate domain like0.9986Inherited
HD-domain/PDEase-like1Inherited
NTF2-like1Inherited
Chaperone J-domain0.4767Inherited
ADC-like0.915Inherited
Cdc48 domain 2-like0.7325Inherited
AN1-like Zinc finger0.5764Inherited
RNase III domain-like0.224Inherited
dsRNA-binding domain-like0.003305Inherited
BAH domain0.001192Inherited
BRK domain-like0.1938Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Doublecortin (DC)0.01116Inherited
HIT/MYND zinc finger-like0.961Inherited
Phospholipase A2, PLA20.6419Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.06195Inherited
Mitotic arrest deficient-like 1, Mad10.0354Inherited
UBA-like0.5518Inherited
Activating enzymes of the ubiquitin-like proteins0.9786Inherited
F-box domain1Inherited
Ankyrin repeat0.3144Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.2953Inherited
Cyclin-like0.2183Inherited
Sec63 N-terminal domain-like0.2529Inherited
DNA polymerase beta, N-terminal domain-like0.4623Inherited
Restriction endonuclease-like0.005362Inherited
PAP/OAS1 substrate-binding domain0.7243Inherited
DUSP-like0.1176Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0.6064Inherited
N-terminal coiled coil domain from apc0.9893Inherited
Tumor suppressor gene product Apc0.9893Inherited
Retrovirus zinc finger-like domains0.8907Inherited
DNA/RNA polymerases0.1597Inherited
Class II aaRS ABD-related0.9207Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49879,52113
  • 49879 - SMAD/FHA domain
  • 52113 - BRCT domain
  • 0Direct
    46785,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    54001,55205
  • 54001 - Cysteine proteinases
  • 55205 - EPT/RTPC-like
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    51905,47576
  • 51905 - FAD/NAD(P)-binding domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0Direct
    47769,140860
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    89837,56112
  • 89837 - Doublecortin (DC)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    47724,57917
  • 47724 - Domain of early E2A DNA-binding protein, ADDBP
  • 57917 - Zn-binding domains of ADDBP
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57997,52540
  • 57997 - Tropomyosin
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55021,56112
  • 55021 - ACT-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57917,57917
  • 57917 - Zn-binding domains of ADDBP
  • 57917 - Zn-binding domains of ADDBP
  • 0Direct
    52540,47473
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47473 - EF-hand
  • 0Direct
    52540,49899
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    143791,54236
  • 143791 - DUSP-like
  • 54236 - Ubiquitin-like
  • 0Direct
    48371,49785
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0Direct
    56741,56349
  • 56741 - Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
  • 56349 - DNA breaking-rejoining enzymes
  • 0Direct
    63763,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    81995,54236
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    48371,47095
  • 48371 - ARM repeat
  • 47095 - HMG-box
  • 0Direct
    55729,47370
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 47370 - Bromodomain
  • 0.000000000000003737Direct
    50249,46785
  • 50249 - Nucleic acid-binding proteins
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00000000000001092Direct
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.00000000000001446Direct
    82199,81822
  • 82199 - SET domain
  • 81822 - RuBisCo LSMT C-terminal, substrate-binding domain
  • 0.00000000000002928Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000000000009307Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0.0000000000004869Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000000000002844Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000000003353Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.00000000001222Direct
    49764,48452
  • 49764 - HSP20-like chaperones
  • 48452 - TPR-like
  • 0.0000000001319Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0000000005658Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000000001113Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.000000001119Direct
    63748,82199
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 0.000000001615Direct
    82199,57903
  • 82199 - SET domain
  • 57903 - FYVE/PHD zinc finger
  • 0.000000001615Direct
    46689,51905
  • 46689 - Homeodomain-like
  • 51905 - FAD/NAD(P)-binding domain
  • 0.000000001766Direct
    52540,101224
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 101224 - HAND domain of the nucleosome remodeling ATPase ISWI
  • 0.000000002657Direct
    101224,46689
  • 101224 - HAND domain of the nucleosome remodeling ATPase ISWI
  • 46689 - Homeodomain-like
  • 0.000000002657Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.000000004093Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.000000004105Direct
    56349,46596
  • 56349 - DNA breaking-rejoining enzymes
  • 46596 - Eukaryotic DNA topoisomerase I, dispensable insert domain
  • 0.000000005348Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.000000008506Direct
    57903,63748
  • 57903 - FYVE/PHD zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 0.00000001509Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0.00000001742Direct
    50978,69322
  • 50978 - WD40 repeat-like
  • 69322 - Tricorn protease domain 2
  • 0.00000002346Direct
    57850,57667
  • 57850 - RING/U-box
  • 57667 - beta-beta-alpha zinc fingers
  • 0.00000002346Direct
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.00000004092Direct
    63451,63451
  • 63451 - LEM domain
  • 63451 - LEM domain
  • 0.00000005424Direct
    90257,57997
  • 90257 - Myosin rod fragments
  • 57997 - Tropomyosin
  • 0.00000007777Direct
    89895,109728
  • 89895 - FYSH domain
  • 109728 - Hypothetical protein AF0491, middle domain
  • 0.00000007878Direct
    54160,82199
  • 54160 - Chromo domain-like
  • 82199 - SET domain
  • 0.0000001354Direct
    48403,140860
  • 48403 - Ankyrin repeat
  • 140860 - Pseudo ankyrin repeat-like
  • 0.0000001585Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000002251Direct
    116846,52540
  • 116846 - MIT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000003051Direct
    56731,52540
  • 56731 - DNA primase core
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000003073Direct
    63748,48371
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 0.0000003073Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000005015Direct
    52540,49879
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49879 - SMAD/FHA domain
  • 0.0000005015Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.0000006137Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000006729Direct
    57850,46689
  • 57850 - RING/U-box
  • 46689 - Homeodomain-like
  • 0.0000009597Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.000001035Direct
    52540,54814
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54814 - Prokaryotic type KH domain (KH-domain type II)
  • 0.000001602Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0.000001822Direct
    54211,56719
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.000001822Direct
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0.000002171Direct
    48371,101447
  • 48371 - ARM repeat
  • 101447 - Formin homology 2 domain (FH2 domain)
  • 0.000003752Direct
    47473,47576
  • 47473 - EF-hand
  • 47576 - Calponin-homology domain, CH-domain
  • 0.000003977Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.000009204Direct
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000009564Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000009928Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.00001869Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.00002024Direct
    56112,90257
  • 56112 - Protein kinase-like (PK-like)
  • 90257 - Myosin rod fragments
  • 0.00002024Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.00002024Direct
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.00002297Direct
    56719,101904
  • 56719 - Type II DNA topoisomerase
  • 101904 - GyrA/ParC C-terminal domain-like
  • 0.00002409Direct
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0.00002409Direct
    54862,53706
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0.00002686Direct
    64356,58038
  • 64356 - SNARE-like
  • 58038 - SNARE fusion complex
  • 0.00003061Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0.00003441Direct
    57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0.00003746Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0.00003746Direct
    54364,55200
  • 54364 - Translation initiation factor IF3, N-terminal domain
  • 55200 - Translation initiation factor IF3, C-terminal domain
  • 0.00003746Direct
    55271,53150
  • 55271 - DNA repair protein MutS, domain I
  • 53150 - DNA repair protein MutS, domain II
  • 0.00003746Direct
    48592,52029
  • 48592 - GroEL equatorial domain-like
  • 52029 - GroEL apical domain-like
  • 0.00003746Direct
    49503,110083
  • 49503 - Cupredoxins
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 0.00003795Direct
    110083,55909
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 55909 - Pentein
  • 0.00003795Direct
    56712,57783
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 57783 - Zinc beta-ribbon
  • 0.00005092Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.00005502Direct
    50978,48371
  • 50978 - WD40 repeat-like
  • 48371 - ARM repeat
  • 0.00005754Direct
    53150,48334
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 0.00005783Direct
    50044,53335
  • 50044 - SH3-domain
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.00006192Direct
    56988,81296
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 0.00006192Direct
    48403,49265
  • 48403 - Ankyrin repeat
  • 49265 - Fibronectin type III
  • 0.00006192Direct
    81901,48452
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 0.00008553Direct
    47473,52540
  • 47473 - EF-hand
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00008937Direct
    48371,50729
  • 48371 - ARM repeat
  • 50729 - PH domain-like
  • 0.0001339Direct
    57997,75553
  • 57997 - Tropomyosin
  • 75553 - Smc hinge domain
  • 0.0001465Direct
    81296,56988
  • 81296 - E set domains
  • 56988 - Anthrax protective antigen
  • 0.0001465Direct
    52540,57997
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57997 - Tropomyosin
  • 0.0001465Direct
    54292,54862
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 0.0001509Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0001563Direct
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.0001649Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0.0002166Direct
    50729,69322
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0.0002169Direct
    52540,75553
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 75553 - Smc hinge domain
  • 0.0002169Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0.0002483Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0.0003141Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0003287Direct
    47794,52540
  • 47794 - Rad51 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0004359Direct
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.0005337Direct
    74924,52058
  • 74924 - Cap-Gly domain
  • 52058 - L domain-like
  • 0.0005337Direct
    54236,57829
  • 54236 - Ubiquitin-like
  • 57829 - Zn-binding ribosomal proteins
  • 0.0005479Direct
    56112,81837
  • 56112 - Protein kinase-like (PK-like)
  • 81837 - BEACH domain
  • 0.0005712Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0006005Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.000702Direct
    117018,56091
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0.0007487Direct
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0.0008804Direct
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.0008891Direct
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.0008891Direct
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.0008891Direct
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0009343Direct
    47220,109885
  • 47220 - alpha-catenin/vinculin-like
  • 109885 - I/LWEQ domain
  • 0.01405Inherited
    47592,55159
  • 47592 - SWIB/MDM2 domain
  • 55159 - eIF1-like
  • 0.002149Inherited
    50447,52156
  • 50447 - Translation proteins
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 0.004073Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.6639Inherited
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.06195Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.3352Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.959Inherited
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.1981Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 1Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.004547Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.008453Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.0012Inherited
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.1176Inherited
    81995,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 53300 - vWA-like
  • 0.5323Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.3911Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.5212Inherited
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0.04266Inherited
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1076Inherited
    46785,158702
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.2476Inherited
    158702,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3352Inherited
    158702,81296
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0.4433Inherited
    50249,57756
  • 50249 - Nucleic acid-binding proteins
  • 57756 - Retrovirus zinc finger-like domains
  • 0.078Inherited
    56014,55124
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 0.002117Inherited
    55124,56014
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0.0175Inherited
    57783,57783
  • 57783 - Zinc beta-ribbon
  • 57783 - Zinc beta-ribbon
  • 0.06807Inherited
    54768,54211
  • 54768 - dsRNA-binding domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01405Inherited
    54814,54821
  • 54814 - Prokaryotic type KH domain (KH-domain type II)
  • 54821 - Ribosomal protein S3 C-terminal domain
  • 0.025Inherited
    54747,46906
  • 54747 - Ribosomal L11/L12e N-terminal domain
  • 46906 - Ribosomal protein L11, C-terminal domain
  • 0.04233Inherited
    56053,56053
  • 56053 - Ribosomal protein L6
  • 56053 - Ribosomal protein L6
  • 0.078Inherited
    50249,50104
  • 50249 - Nucleic acid-binding proteins
  • 50104 - Translation proteins SH3-like domain
  • 0.2158Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1453Inherited
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 1Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    82171,50978
  • 82171 - DPP6 N-terminal domain-like
  • 50978 - WD40 repeat-like
  • 0.003517Inherited
    52540,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 0.004073Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.6591Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.7619Inherited
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.1981Inherited
    53448,50370
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 50370 - Ricin B-like lectins
  • 0.3142Inherited
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.3784Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 1Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 1Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.1379Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.6071Inherited
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.09233Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 1Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 0.003243Inherited
    46934,101238
  • 46934 - UBA-like
  • 101238 - XPC-binding domain
  • 0.001192Inherited
    52113,142921
  • 52113 - BRCT domain
  • 142921 - WGR domain-like
  • 0.005353Inherited
    50249,52113
  • 50249 - Nucleic acid-binding proteins
  • 52113 - BRCT domain
  • 0.007133Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.002319Inherited
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.1615Inherited
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.7436Inherited
    50978,48452
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0.04233Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.002675Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.5253Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.958Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 1Inherited
    50156,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 0.04233Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.004529Inherited
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.001828Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 1Inherited
    46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0.2825Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.7449Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.03377Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.04236Inherited
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.02234Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004545Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.004762Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.7226Inherited
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.9208Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.6533Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited
    50891,48452
  • 50891 - Cyclophilin-like
  • 48452 - TPR-like
  • 0.004073Inherited
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.4151Inherited
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0.6591Inherited
    52156,50447
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 50447 - Translation proteins
  • 0.0236Inherited
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.01412Inherited
    142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.06631Inherited
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0.001141Inherited
    100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0.002065Inherited
    88723,47807
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 0.1407Inherited
    117281,50965
  • 117281 - Kelch motif
  • 50965 - Galactose oxidase, central domain
  • 0.001389Inherited
    49758,49758
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.003517Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.8396Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.9656Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 1Inherited
    53098,47781
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 0.021Inherited
    158832,53098
  • 158832 - Tex N-terminal region-like
  • 53098 - Ribonuclease H-like
  • 0.021Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.8601Inherited
    54236,74924
  • 54236 - Ubiquitin-like
  • 74924 - Cap-Gly domain
  • 0.02904Inherited
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.622Inherited
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.7331Inherited
    49265,56112
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.003624Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 1Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.02877Inherited
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.001535Inherited
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.004174Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.02877Inherited
    81324,51735
  • 81324 - Voltage-gated potassium channels
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.06195Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.1938Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.4151Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 1Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 1Inherited
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 1Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.002675Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.002675Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.3188Inherited
    57997,90257
  • 57997 - Tropomyosin
  • 90257 - Myosin rod fragments
  • 0.003517Inherited
    56112,64268
  • 56112 - Protein kinase-like (PK-like)
  • 64268 - PX domain
  • 0.02441Inherited
    64268,49562
  • 64268 - PX domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.02441Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 1Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 1Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.1453Inherited
    82199,48452
  • 82199 - SET domain
  • 48452 - TPR-like
  • 0.00915Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.9728Inherited
    50974,50978
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.001192Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.2347Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.1114Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.1379Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 1Inherited
    69645,69645
  • 69645 - Arp2/3 complex subunits
  • 69645 - Arp2/3 complex subunits
  • 0.05708Inherited
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0.002675Inherited
    48726,56112
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0.0398Inherited
    48452,48371
  • 48452 - TPR-like
  • 48371 - ARM repeat
  • 0.02904Inherited
    50729,46785
  • 50729 - PH domain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.5323Inherited
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 1Inherited
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 1Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 1Inherited
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.2825Inherited
    49599,54001
  • 49599 - TRAF domain-like
  • 54001 - Cysteine proteinases
  • 0.9742Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.5142Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.01994Inherited
    81837,50978
  • 81837 - BEACH domain
  • 50978 - WD40 repeat-like
  • 0.5698Inherited
    54277,57850
  • 54277 - CAD & PB1 domains
  • 57850 - RING/U-box
  • 0.07343Inherited
    48464,57903
  • 48464 - ENTH/VHS domain
  • 57903 - FYVE/PHD zinc finger
  • 0.003517Inherited
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.127Inherited
    50985,48065
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 0.127Inherited
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.1981Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 1Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.002529Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.2141Inherited
    50998,50978
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 50978 - WD40 repeat-like
  • 0.06143Inherited
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.3934Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.3702Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 1Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.8417Inherited
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 1Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 1Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.7269Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.9758Inherited
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0.01116Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.007639Inherited
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0.01405Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.3934Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.9132Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.963Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 1Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.8072Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3352Inherited
    47576,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.5698Inherited
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.4766Inherited
    57997,57997
  • 57997 - Tropomyosin
  • 57997 - Tropomyosin
  • 0.127Inherited
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.5323Inherited
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5323Inherited
    51230,52777
  • 51230 - Single hybrid motif
  • 52777 - CoA-dependent acyltransferases
  • 0.01428Inherited
    55666,46915
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0.05886Inherited
    46915,54211
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.05886Inherited
    55666,54791
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.1649Inherited
    54791,50249
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0.1649Inherited
    52540,54211
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.002221Inherited
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0.05994Inherited
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.09811Inherited
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.1407Inherited
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0.1407Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.01153Inherited
    50729,47912
  • 50729 - PH domain-like
  • 47912 - Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
  • 0.07343Inherited
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.08501Inherited
    58014,51064
  • 58014 - Coiled-coil domain of nucleotide exchange factor GrpE
  • 51064 - Head domain of nucleotide exchange factor GrpE
  • 0.07343Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.01152Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.02343Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.4453Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.9917Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 1Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.8601Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.1938Inherited
    47413,47413
  • 47413 - lambda repressor-like DNA-binding domains
  • 47413 - lambda repressor-like DNA-binding domains
  • 0.002149Inherited
    50249,55550
  • 50249 - Nucleic acid-binding proteins
  • 55550 - SH2 domain
  • 0.002149Inherited
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.2763Inherited
    102114,55729
  • 102114 - Radical SAM enzymes
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0.127Inherited
    88697,82199
  • 88697 - PUA domain-like
  • 82199 - SET domain
  • 0.07343Inherited
    53335,53335
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.04082Inherited
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.04082Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.02669Inherited
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.3784Inherited
    49758,49562
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001192Inherited
    75553,52540
  • 75553 - Smc hinge domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1402Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.1393Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.07126Inherited
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.03438Inherited
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0.002675Inherited
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.6828Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.01405Inherited
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.2158Inherited
    54277,50156
  • 54277 - CAD & PB1 domains
  • 50156 - PDZ domain-like
  • 0.8396Inherited
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0.66Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 1Inherited
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.02567Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.02328Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,54236,50729
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    46966,47473,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49265,49265,48726
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    51905,47576,57716
  • 51905 - FAD/NAD(P)-binding domain
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    48371,47095,47095
  • 48371 - ARM repeat
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    47724,57917,57917
  • 47724 - Domain of early E2A DNA-binding protein, ADDBP
  • 57917 - Zn-binding domains of ADDBP
  • 57917 - Zn-binding domains of ADDBP
  • 0Direct
    50978,50978,48452
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0Direct
    63763,47095,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    52540,49899,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,47473,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47473 - EF-hand
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46785,57903,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    48403,47769,140860
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    63748,48371,49785
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0Direct
    56112,48726,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 9.676e-16Direct
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.00000000000001446Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.00000000000008894Direct
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00000000002013Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000000001319Direct
    49899,57196,57184
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0000000004754Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0000000005658Direct
    52540,52540,101224
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 101224 - HAND domain of the nucleosome remodeling ATPase ISWI
  • 0.000000001343Direct
    46689,51905,54373
  • 46689 - Homeodomain-like
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0.000000001766Direct
    52540,101224,46689
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 101224 - HAND domain of the nucleosome remodeling ATPase ISWI
  • 46689 - Homeodomain-like
  • 0.000000002657Direct
    101224,46689,46689
  • 101224 - HAND domain of the nucleosome remodeling ATPase ISWI
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.000000002657Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000000003478Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000000004105Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000005036Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000005234Direct
    56741,56349,46596
  • 56741 - Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
  • 56349 - DNA breaking-rejoining enzymes
  • 46596 - Eukaryotic DNA topoisomerase I, dispensable insert domain
  • 0.000000005348Direct
    57903,63748,82199
  • 57903 - FYVE/PHD zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 0.00000001509Direct
    63748,82199,57903
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 57903 - FYVE/PHD zinc finger
  • 0.00000001509Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0000001354Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000005015Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0000005015Direct
    47031,50729,55550
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.0000006184Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000006936Direct
    55874,54211,56719
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.000005653Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.000009032Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.000009204Direct
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000009564Direct
    48452,81901,48452
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 0.000009564Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0.000009928Direct
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000009928Direct
    57903,57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.00001468Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0.00001678Direct
    81901,48452,48452
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.00001869Direct
    54292,54862,53706
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0.00001916Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.00002024Direct
    46785,46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00002024Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.00002024Direct
    49503,110083,55909
  • 49503 - Cupredoxins
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 55909 - Pentein
  • 0.00003795Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00003812Direct
    50249,57756,57756
  • 50249 - Nucleic acid-binding proteins
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.00005092Direct
    53150,48334,52540
  • 53150 - DNA repair protein MutS, domain II
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00005783Direct
    56988,81296,81296
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.00006192Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00006192Direct
    81296,56988,81296
  • 81296 - E set domains
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 0.00006192Direct
    50156,50729,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0001339Direct
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0.0001445Direct
    52540,57997,75553
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57997 - Tropomyosin
  • 75553 - Smc hinge domain
  • 0.0001465Direct
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.0001649Direct
    57783,57783,57783
  • 57783 - Zinc beta-ribbon
  • 57783 - Zinc beta-ribbon
  • 57783 - Zinc beta-ribbon
  • 0.0002169Direct
    57889,50729,69322
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0.0002169Direct
    52540,48452,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0002957Direct
    50978,48371,57850
  • 50978 - WD40 repeat-like
  • 48371 - ARM repeat
  • 57850 - RING/U-box
  • 0.0005712Direct
    117018,56091,50249
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0.0006005Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0008276Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.0008804Direct
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.0008891Direct
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0008891Direct
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.0008891Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0.0009698Direct
    50447,52156,50447
  • 50447 - Translation proteins
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 50447 - Translation proteins
  • 0.002952Inherited
    52540,50447,52156
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 0.004073Inherited
    47220,47220,109885
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 109885 - I/LWEQ domain
  • 0.02441Inherited
    75399,75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.4823Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.004547Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.004547Inherited
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.1176Inherited
    81995,53300,81995
  • 81995 - beta-sandwich domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.3253Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.3911Inherited
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1615Inherited
    46785,158702,52540
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1981Inherited
    52540,46785,158702
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.2476Inherited
    46785,158702,81296
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0.2825Inherited
    158702,52540,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3352Inherited
    56014,55124,56014
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 0.002117Inherited
    55124,56014,55124
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 56014 - Nitrite and sulphite reductase 4Fe-4S domain-like
  • 55124 - Nitrite/Sulfite reductase N-terminal domain-like
  • 0.002117Inherited
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.5646Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.5413Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.6591Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.6591Inherited
    50729,57863,48403
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.04233Inherited
    103657,50729,57863
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.2825Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.001031Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6071Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.02876Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    52113,142921,47587
  • 52113 - BRCT domain
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.003517Inherited
    56091,50249,52113
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 52113 - BRCT domain
  • 0.007133Inherited
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.9742Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.02441Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004545Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.006653Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.7159Inherited
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.9171Inherited
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.05896Inherited
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0.001141Inherited
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0.002065Inherited
    54001,49758,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.001192Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.8396Inherited
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 1Inherited
    158832,53098,47781
  • 158832 - Tex N-terminal region-like
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 0.021Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.1369Inherited
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.622Inherited
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.7331Inherited
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.7331Inherited
    48726,49265,56112
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.001131Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.9474Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.1938Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 1Inherited
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.002675Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 1Inherited
    90257,57997,90257
  • 90257 - Myosin rod fragments
  • 57997 - Tropomyosin
  • 90257 - Myosin rod fragments
  • 0.001192Inherited
    48371,56112,64268
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 64268 - PX domain
  • 0.02441Inherited
    56112,64268,49562
  • 56112 - Protein kinase-like (PK-like)
  • 64268 - PX domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.02441Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.7531Inherited
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.06691Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.1769Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.5212Inherited
    48452,48371,48371
  • 48452 - TPR-like
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.007714Inherited
    48726,48726,56112
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0.02343Inherited
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 1Inherited
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 1Inherited
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 1Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    50729,81837,50978
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 50978 - WD40 repeat-like
  • 0.5698Inherited
    48065,50729,82185
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.127Inherited
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.127Inherited
    50985,48065,50729
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.127Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 1Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.3251Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.8912Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4831Inherited
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 1Inherited
    47576,57716,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.5698Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.9693Inherited
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.127Inherited
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.5323Inherited
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5323Inherited
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5323Inherited
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7086Inherited
    48065,50729,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.7331Inherited
    46915,54211,55666
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0.05886Inherited
    54211,55666,46915
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0.05886Inherited
    55666,46915,54211
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.05886Inherited
    55666,54791,50249
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0.1649Inherited
    54211,55666,54791
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.1649Inherited
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.09114Inherited
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.1221Inherited
    90209,90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.001389Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01141Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 1Inherited
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.002675Inherited
    57903,57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.0185Inherited
    63748,63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.2158Inherited
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.03583Inherited
    46585,46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0.3934Inherited
    54001,49758,49562
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001192Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.02867Inherited
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.7531Inherited
    57756,57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.025Inherited


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