SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): blood circulation

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ + 2:   system process [GO:0003008] <9>(12|13) (189|144|86)
+ 1:   circulatory system process [GO:0003013] <4>(8|8) (76|59|38)
0:   blood circulation [GO:0008015] <6>(8|8) (72|57|38)
- 1:   regulation of blood pressure [GO:0008217] <6>(4|4) (31|18|12)
- 1:   regulation of vascular permeability [GO:0043114] <4>(0|0) (9|9|9)
- 1:   regulation of blood vessel size [GO:0050880] <2>(2|2) (21|8|5)
- 1:   heart contraction [GO:0060047] <1>(4|4) (19|16|10)
- 1:   gastric mucosal blood circulation [GO:1990768](0|0) (0|0|0)
- 1:   monocyte migration into blood stream [GO:0035703](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Core binding factor beta, CBF00Direct
Cu,Zn superoxide dismutase-like00.00000000000009057Direct
EF-hand0.0000000028930.000005118Direct
Tropomyosin0.0000000010270.00000009961Direct
Family A G protein-coupled receptor-like0.0030730Inherited
NAD(P)-linked oxidoreductase0.00093790.03353Inherited
HLH, helix-loop-helix DNA-binding domain0.000000000012750.1178Inherited
Trypsin-like serine proteases0.0000043340.01057Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Calmodulin-like0.000000000049650.00000001717Direct
Core binding factor beta, CBF0.0000000000000011680Direct
Cu,Zn superoxide dismutase-like00.0000000000003774Direct
Rhodopsin-like0.00044210Direct
Tropomyosin0.0000000011950.0000001578Direct
Aldo-keto reductases (NADP)0.0016930.04935Inherited
HLH, helix-loop-helix DNA-binding domain0.000000000031280.1998Inherited
Eukaryotic proteases0.000007670.001896Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Leukotriene A4 hydrolase N-terminal domain0Direct
Troponin coil-coiled subunits0Direct
Family A G protein-coupled receptor-like0Direct
Core binding factor beta, CBF0Direct
Transcription factor STAT-4 N-domain0Direct
STAT0Direct
GAF domain-like0.000000000000001898Direct
Cu,Zn superoxide dismutase-like0.00000000000004808Direct
Metalloproteases ("zincins"), catalytic domain0.0000000000001763Direct
Satiety factor CART (cocaine and amphetamine regulated transcript)0.0000000000002508Direct
HD-domain/PDEase-like0.0000000000009955Direct
GLA-domain0.000000000192Direct
Heme-dependent peroxidases0.0000000007273Direct
TNF-like0.0000000008343Direct
(Phosphotyrosine protein) phosphatases II0.00000001442Direct
Nitric oxide (NO) synthase oxygenase domain0.00000004241Direct
Fibronectin type III0.00000004826Direct
Tropomyosin0.00000006184Direct
EF-hand0.00000335Direct
Connexin430.000004624Direct
Heparin-binding domain from vascular endothelial growth factor0.000006957Direct
Myosin rod fragments0.000007862Direct
CalX-like0.0000107Direct
Fibrinogen coiled-coil and central regions0.00001703Direct
Metal cation-transporting ATPase, ATP-binding domain N0.00002522Direct
Myosin S1 fragment, N-terminal domain0.00003924Direct
Notch domain0.0001091Direct
cAMP-binding domain-like0.0001185Direct
Calcium ATPase, transduction domain A0.0001321Direct
YWTD domain0.0001494Direct
Riboflavin synthase domain-like0.000192Direct
Cystine-knot cytokines0.000197Direct
Calcium ATPase, transmembrane domain M0.0002056Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0002296Direct
Pseudo ankyrin repeat-like0.0002611Direct
PYP-like sensor domain (PAS domain)0.00027Direct
IP3 receptor type 1 binding core, domain 20.0002839Direct
alpha-catenin/vinculin-like0.0002878Direct
C-terminal domain of PLC-beta0.0004921Direct
Calponin-homology domain, CH-domain0.0005213Direct
Cytochrome P4500.0006181Direct
Serpins0.0007287Direct
A DNA-binding domain in eukaryotic transcription factors0.0007613Direct
Dihydrofolate reductase-like0.0008192Direct
Voltage-gated potassium channels1Inherited
BAR/IMD domain-like0.03918Inherited
MIR domain0.00328Inherited
Intermediate filament protein, coiled coil region0.007682Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.0127Inherited
Immunoglobulin0.01907Inherited
Flavoproteins0.001144Inherited
Glutamine synthetase/guanido kinase0.002377Inherited
NAD(P)-linked oxidoreductase0.02572Inherited
SH2 domain0.577Inherited
SH3-domain0.6973Inherited
HLH, helix-loop-helix DNA-binding domain0.09382Inherited
PLC-like phosphodiesterases0.0117Inherited
Ankyrin repeat0.001176Inherited
Fibrinogen C-terminal domain-like0.001738Inherited
PDZ domain-like0.84Inherited
EGF/Laminin1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like0.001153Inherited
Phoshotransferase/anion transport protein0.005198Inherited
Growth factor receptor domain1Inherited
Concanavalin A-like lectins/glucanases0.7578Inherited
Protease propeptides/inhibitors0.02439Inherited
Acid proteases0.04046Inherited
Trypsin-like serine proteases0.007856Inherited
SRCR-like0.01125Inherited
Frizzled cysteine-rich domain0.01495Inherited
LDL receptor-like module0.0801Inherited
MFS general substrate transporter1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0Direct
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.00000000000005311Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000002364Direct
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0.0000000116Direct
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.00000009591Direct
    48452,48371
  • 48452 - TPR-like
  • 48371 - ARM repeat
  • 0.0000001002Direct
    63501,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 0.0000001437Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.000001672Direct
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.000002946Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0.000003278Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.000005322Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.000006211Direct
    51230,52777
  • 51230 - Single hybrid motif
  • 52777 - CoA-dependent acyltransferases
  • 0.00001402Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.00002018Direct
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.00002875Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 0.00003369Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00004121Direct
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.00004488Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00005219Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.00005969Direct
    49265,56112
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.00008344Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.00008919Direct
    81324,51735
  • 81324 - Voltage-gated potassium channels
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.00009743Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.0001351Direct
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.0001959Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0002091Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.0002191Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.0002434Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002825Direct
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.0002863Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0003083Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.0003225Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.000334Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0003346Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.0003884Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.0005574Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0006328Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0006752Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001046Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.001001Inherited
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0.001004Inherited
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 1Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.001252Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.003574Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.9283Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.9283Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0341Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.8573Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01176Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    63825,57196,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000000007131Direct
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000006573Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.000000004323Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000002301Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00000002301Direct
    49265,49265,48726
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.00000003203Direct
    63501,57424,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0000001437Direct
    57424,57424,56487
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.0000001437Direct
    56112,48726,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000002491Direct
    57196,57184,63825
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0000004767Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000008043Direct
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.000001784Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00001048Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00001473Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.00001522Direct
    48726,49265,56112
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0.00002626Direct
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.00002875Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.00002875Direct
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00002875Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00003924Direct
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00005726Direct
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00007692Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00009615Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0002839Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.0007303Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.001004Inherited
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.004552Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05389Inherited
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.006875Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001792Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.9283Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.007611Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)