SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Biological Process (BP): regulation of actin polymerization or depolymerization

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + + 5:   biological_process [GO:0008150] <24>
+ + + + 4:   cellular component organization or biogenesis [GO:0071840] <2>(123|122) (647|619|358)
+ + + + 4:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ + + + 4:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + + 4:   regulation of biological quality [GO:0065008] <46>(62|65) (453|402|258)
+ + + + 4:   regulation of organelle organization [GO:0033043] <27>(20|20) (194|151|67)
+ + + + 4:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ + + 3:   cellular component organization [GO:0016043] <33>(113|104) (617|594|349)
+ + + 3:   regulation of actin filament-based process [GO:0032970] <3>(5|6) (71|50|28)
+ + + 3:   regulation of anatomical structure size [GO:0090066] <7>(13|12) (133|108|69)
+ + + 3:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + + 3:   regulation of cytoskeleton organization [GO:0051493] <6>(8|9) (93|71|36)
+ + + 3:   single-organism cellular process [GO:0044763] <194>(233|302) (895|984|562)
+ + 2:   regulation of actin cytoskeleton organization [GO:0032956] <7>(5|6) (61|47|26)
+ + 2:   regulation of cellular component organization [GO:0051128] <52>(35|32) (311|310|174)
+ + 2:   regulation of cellular component size [GO:0032535] <12>(10|10) (99|87|55)
+ 1:   regulation of actin filament length [GO:0030832] <1>(5|6) (38|29|18)
+ 1:   regulation of supramolecular fiber organization [GO:1902903] <11>(8|8) (72|53|30)
0:   regulation of actin polymerization or depolymerization [GO:0008064] <2>(5|6) (38|29|18)
- 1:   regulation of actin filament polymerization [GO:0030833] <4>(4|5) (31|22|15)
- 1:   regulation of actin filament depolymerization [GO:0030834] <3>(1|3) (18|11|11)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Actin depolymerizing proteins00Direct
Arp2/3 complex 21 kDa subunit ARPC30.000000000012230.000000000117Direct
Arp2/3 complex subunits0.000000000028730Direct
Subunits of heterodimeric actin filament capping protein Capz00Direct
Profilin (actin-binding protein)0.031450.001007Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 21 kDa subunit ARPC30.000000000034230.000000000279Direct
Arp2/3 complex subunits0.000000000065210Direct
Capz alpha-1 subunit0.000000000088810.000000000009993Direct
Capz beta-1 subunit00Direct
Cofilin-like00Direct
Profilin (actin-binding protein)0.026630.001228Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
VHP, Villin headpiece domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
HR1 repeat0Direct
Actin depolymerizing proteins0Direct
Arp2/3 complex subunits0Direct
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.000000000001922Direct
Arp2/3 complex 21 kDa subunit ARPC30.00000000006716Direct
Lipoxigenase0.0000000001062Direct
Arp2/3 complex 16 kDa subunit ARPC50.000000001027Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0000001944Direct
FF domain0.0000002785Direct
SH3-domain0.0000004111Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000000708Direct
AraD/HMP-PK domain-like0.0000009462Direct
FAT domain of focal adhesion kinase0.000003123Direct
BAR/IMD domain-like0.00001416Direct
Sec7 domain0.00002953Direct
Interleukin 8-like chemokines0.00007603Direct
RNI-like0.0001425Direct
NHL repeat0.000553Direct
Profilin (actin-binding protein)0.0007173Direct
Ankyrin repeat1Inherited
PDZ domain-like0.06114Inherited
Protein kinase-like (PK-like)0.9079Inherited
SAM/Pointed domain1Inherited
Second domain of FERM0.03696Inherited
PH domain-like0.1655Inherited
Ubiquitin-like0.6429Inherited
Formin homology 2 domain (FH2 domain)0.02384Inherited
Actin-like ATPase domain0.7301Inherited
HAD-like0.2723Inherited
Moesin tail domain0.2655Inherited
TSP-1 type 1 repeat0.09899Inherited
Sema domain0.09899Inherited
Plexin repeat0.4535Inherited
CRAL/TRIO domain0.05367Inherited
DBL homology domain (DH-domain)1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.00000000000001092Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.00000000000001622Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.000000000000126Direct
    69645,69645
  • 69645 - Arp2/3 complex subunits
  • 69645 - Arp2/3 complex subunits
  • 0.0000000000002716Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000000002669Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.00000000004425Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0000000005074Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.000000002525Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0.000000006175Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000000309Direct
    50729,46785
  • 50729 - PH domain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00000004997Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.0000593Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.0000698Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.00007414Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003004Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0007934Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0921Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.05878Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.7301Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.002884Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.09899Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.002032Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.004588Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.004588Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.09899Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    50044,55550,50729
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0Direct
    55550,50044,55550
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000000000000003737Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00000000000002667Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000000000009392Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000000002669Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000000002669Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0000000005074Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000000309Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000000309Direct
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00000007649Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000001579Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00000857Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0921Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001179Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.004588Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.09899Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)