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Biological Process (BP): regulation of signal transduction

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + 2:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + 2:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ 1:   regulation of cell communication [GO:0010646] <25>(42|44) (331|347|194)
+ 1:   regulation of response to stimulus [GO:0048583] <43>(57|53) (384|420|248)
+ 1:   regulation of signaling [GO:0023051] <13>(42|44) (331|349|197)
0:   regulation of signal transduction [GO:0009966] <71>(39|40) (308|319|183)
- 1:   negative regulation of signal transduction [GO:0009968] <74>(12|9) (184|157|89)
- 1:   positive regulation of signal transduction [GO:0009967] <69>(21|23) (166|139|80)
- 1:   regulation of intracellular signal transduction [GO:1902531] <25>(18|23) (194|173|89)
- 1:   regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] <21>(4|4) (33|26|8)
- 1:   regulation of receptor activity [GO:0010469] <20>(0|0) (31|18|6)
- 1:   regulation of toll-like receptor signaling pathway [GO:0034121] <19>(4|3) (24|10|3)
- 1:   regulation of cytokine-mediated signaling pathway [GO:0001959] <18>(2|1) (30|27|11)
- 1:   regulation of Wnt signaling pathway [GO:0030111] <9>(1|1) (47|40|15)
- 1:   regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0090092] <9>(3|2) (55|48|44)
- 1:   regulation of apoptotic signaling pathway [GO:2001233] <8>(4|4) (45|18|7)
- 1:   regulation of signal transduction in response to host [GO:0075147] <7>(0|0) (0|0|0)
- 1:   modulation of excitatory postsynaptic potential [GO:0098815] <5>(0|0) (15|10|5)
- 1:   regulation of endoplasmic reticulum unfolded protein response [GO:1900101] <5>(1|1) (7|4|3)
- 1:   regulation of glutamate receptor signaling pathway [GO:1900449] <5>(0|0) (11|6|3)
- 1:   regulation of intracellular steroid hormone receptor signaling pathway [GO:0033143] <5>(1|1) (20|5|0)
- 1:   adaptation of signaling pathway [GO:0023058] <4>(0|0) (4|2|1)
- 1:   regulation of ERBB signaling pathway [GO:1901184] <4>(0|0) (36|27|10)
- 1:   regulation of Notch signaling pathway [GO:0008593] <4>(1|0) (40|43|29)
- 1:   regulation of SREBP signaling pathway [GO:2000638] <4>(0|0) (0|0|0)
- 1:   regulation of antigen receptor-mediated signaling pathway [GO:0050854] <4>(1|0) (7|8|4)
- 1:   regulation of fibroblast growth factor receptor signaling pathway [GO:0040036] <4>(0|0) (5|5|1)
- 1:   regulation of platelet-derived growth factor receptor signaling pathway [GO:0010640] <4>(1|1) (4|2|0)
- 1:   regulation of smoothened signaling pathway [GO:0008589] <4>(0|0) (18|11|4)
- 1:   regulation of auxin mediated signaling pathway [GO:0010928] <3>(0|0) (2|1|0)
- 1:   regulation of brain-derived neurotrophic factor receptor signaling pathway [GO:0031548] <3>(0|0) (1|1|0)
- 1:   regulation of glucose mediated signaling pathway [GO:1902659] <3>(0|0) (0|0|0)
- 1:   regulation of insulin receptor signaling pathway [GO:0046626] <3>(1|1) (11|8|4)
- 1:   regulation of signal transduction involved in conjugation with cellular fusion [GO:0060238] <3>(0|0) (1|0|0)
- 1:   regulation of CD40 signaling pathway [GO:2000348] <2>(0|0) (2|1|0)
- 1:   regulation of Fas signaling pathway [GO:1902044] <2>(0|0) (2|2|1)
- 1:   regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368] <2>(0|0) (0|0|0)
- 1:   regulation of Roundabout signaling pathway [GO:0035386] <2>(0|0) (2|1|0)
- 1:   regulation of Toll signaling pathway [GO:0008592] <2>(2|2) (4|1|0)
- 1:   regulation of abscisic acid-activated signaling pathway [GO:0009787] <2>(1|0) (5|0|0)
- 1:   regulation of anti-Mullerian hormone signaling pathway [GO:1902612] <2>(0|0) (0|0|0)
- 1:   regulation of apolipoprotein A-I-mediated signaling pathway [GO:1905094] <2>(0|0) (0|0|0)
- 1:   regulation of brassinosteroid mediated signaling pathway [GO:1900457] <2>(0|0) (1|0|0)
- 1:   regulation of cytokinin-activated signaling pathway [GO:0080036] <2>(0|0) (3|1|0)
- 1:   regulation of ephrin receptor signaling pathway [GO:1901187] <2>(0|0) (0|0|0)
- 1:   regulation of gibberellic acid mediated signaling pathway [GO:0009937] <2>(0|0) (2|0|0)
- 1:   regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric [GO:2000733] <2>(0|0) (1|1|0)
- 1:   regulation of glucocorticoid mediated signaling pathway [GO:1900169] <2>(0|0) (0|0|0)
- 1:   regulation of growth hormone receptor signaling pathway [GO:0060398] <2>(0|0) (2|0|0)
- 1:   regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202] <2>(0|0) (1|0|0)
- 1:   regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902071] <2>(0|0) (1|0|0)
- 1:   regulation of insulin-like growth factor receptor signaling pathway [GO:0043567] <2>(0|0) (9|5|4)
- 1:   regulation of integrin-mediated signaling pathway [GO:2001044] <2>(1|1) (6|1|1)
- 1:   regulation of lipopolysaccharide-mediated signaling pathway [GO:0031664] <2>(0|0) (8|6|2)
- 1:   regulation of netrin-activated signaling pathway [GO:1902841] <2>(0|0) (0|0|0)
- 1:   regulation of neuronal signal transduction [GO:1902847] <2>(0|0) (0|0|0)
- 1:   regulation of neurotrophin TRK receptor signaling pathway [GO:0051386] <2>(0|0) (0|0|0)
- 1:   regulation of osmosensory signaling pathway [GO:0120027] <2>(0|0) (1|0|0)
- 1:   regulation of peptidoglycan recognition protein signaling pathway [GO:0061058] <2>(0|0) (1|0|0)
- 1:   regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358] <2>(1|1) (4|1|0)
- 1:   regulation of red or far-red light signaling pathway [GO:0090227] <2>(0|0) (0|0|0)
- 1:   regulation of retinoic acid receptor signaling pathway [GO:0048385] <2>(2|2) (5|0|0)
- 1:   regulation of salicylic acid mediated signaling pathway [GO:2000031] <2>(0|0) (1|0|0)
- 1:   regulation of semaphorin-plexin signaling pathway [GO:2001260] <2>(0|0) (4|9|9)
- 1:   regulation of sevenless signaling pathway [GO:0045501] <2>(0|0) (2|1|0)
- 1:   regulation of signal transduction by receptor internalization [GO:0038009] <2>(0|0) (0|0|0)
- 1:   regulation of sphingolipid mediated signaling pathway [GO:1902068] <2>(0|0) (0|0|0)
- 1:   regulation of thyroid hormone mediated signaling pathway [GO:0002155] <2>(0|0) (0|0|0)
- 1:   regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947] <2>(2|2) (22|21|13)
- 1:   regulation of vascular endothelial growth factor signaling pathway [GO:1900746] <2>(0|0) (13|9|8)
- 1:   regulation of vitamin D receptor signaling pathway [GO:0070562] <2>(0|0) (1|0|0)
- 1:   extracellular regulation of signal transduction [GO:1900115] <1>(0|0) (3|9|21)
- 1:   modulation of inhibitory postsynaptic potential [GO:0098828] <1>(0|0) (5|0|0)
- 1:   regulation of jasmonic acid mediated signaling pathway [GO:2000022](0|0) (0|0|0)
- 1:   regulation of postsynapse to nucleus signaling pathway [GO:1905539](0|0) (0|0|0)
- 1:   signal clustering [GO:1990256](0|0) (3|3|3)
- 1:   signal complex assembly [GO:0007172](0|0) (2|1|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bcl-2 inhibitors of programmed cell death0.00014310.0003025Direct
Cu,Zn superoxide dismutase-like0.0000000051930.0009034Direct
Cytokine0.000020390.00000146Direct
Regulator of G-protein signaling, RGS0.0000000000045050Direct
Roadblock/LC7 domain00Direct
EF-hand0.43610.05716Inherited
TIMP-like0.000000000000037410.002062Inherited
(Phosphotyrosine protein) phosphatases II0.0017440Inherited
Nqo5-like0.00001430.002207Inherited
Carbohydrate phosphatase0.000077440.03357Inherited
Interleukin 8-like chemokines0.63411Inherited
Family A G protein-coupled receptor-like0.4660.3872Inherited
Metallothionein0.00015220.01983Inherited
Mitochondrial carrier0.88121Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.33581Inherited
Cystine-knot cytokines10.001062Inherited
Phosphoglycerate mutase-like0.00014310.01635Inherited
NAD(P)-linked oxidoreductase0.23461Inherited
Lipocalins0.0012080.003287Inherited
Immunoglobulin11Inherited
Calcium-dependent phosphotriesterase0.000003120.0883Inherited
ALDH-like0.78541Inherited
Insulin-like0.19140.6587Inherited
Trypsin-like serine proteases11Inherited
Serpins0.40881Inherited
Protein kinase-like (PK-like)0.12980.0000000000001847Inherited
L30e-like0.0088360.7269Inherited
Ankyrin repeat0.037450.06636Inherited
Cytochrome P4500.000092721Inherited
Radical SAM enzymes0.14511Inherited
P-loop containing nucleoside triphosphate hydrolases0.96931Inherited
Activating enzymes of the ubiquitin-like proteins0.00010560.04015Inherited
Spermadhesin, CUB domain0.000000045040.979Inherited
WD40 repeat-like0.11440.04841Inherited
4-helical cytokines0.40850.5936Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.19190.9407Inherited
Nucleotide-diphospho-sugar transferases0.86291Inherited
Transducin (heterotrimeric G protein), gamma chain0.0049860.0000000001097Inherited
DEATH domain0.0000069531Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bcl-2 inhibitors of programmed cell death0.00010260.000295Direct
Cyclin A/CDK2-associated p19, Skp20.00000030440.00003831Direct
Dual specificity phosphatase-like0.00031990.0000000000005758Direct
Fibroblast growth factors (FGF)00.0000001114Direct
Histidine acid phosphatase00.00002067Direct
Regulator of G-protein signaling, RGS0.000000000011280Direct
Retinol binding protein-like0.0000070510.00002493Direct
Roadblock/LC7 domain00Direct
SGL-like0.000000017720.000022Direct
Tissue inhibitor of metalloproteinases, TIMP0.00000000000018580.000000005764Direct
S100 proteins0.064060.1687Inherited
Nqo5-like0.000023180.002661Inherited
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0.0001140.04638Inherited
Short-chain cytokines0.39380.236Inherited
Interleukin 8-like chemokines0.56461Inherited
Cu,Zn superoxide dismutase-like0.000000017230.00236Inherited
Rhodopsin-like0.52690.2653Inherited
Penta-EF-hand proteins0.087980.000005665Inherited
Mitochondrial carrier0.90981Inherited
Proteasome subunits0.21331Inherited
Interferons/interleukin-10 (IL-10)0.42720.9324Inherited
Aldo-keto reductases (NADP)0.3381Inherited
RhoGDI-like0.0012770.1054Inherited
Calmodulin-like0.0091680.9447Inherited
ALDH-like0.82731Inherited
Insulin-like0.16640.636Inherited
Eukaryotic proteases11Inherited
Serpins0.36211Inherited
Protein kinases, catalytic subunit0.13830Inherited
Cystathionine synthase-like0.29571Inherited
Ankyrin repeat0.030650.07325Inherited
Cytochrome P4500.00027331Inherited
MoCo biosynthesis proteins0.000044510.0293Inherited
Ubiquitin activating enzymes (UBA)0.00011660.001574Inherited
Molybdenum cofactor biosynthesis protein MoeB0.02350.3113Inherited
Spermadhesin, CUB domain0.000000065480.9658Inherited
WD40-repeat0.084730.3634Inherited
Long-chain cytokines0.38710.4177Inherited
Metallothionein0.00033860.0371Inherited
Transducin (heterotrimeric G protein), gamma chain0.0071070.00000008318Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Roadblock/LC7 domain0Direct
Regulator of G-protein signaling, RGS0Direct
FLJ32549 domain-like0Direct
PH domain-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Ubiquitin-like0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Domain from hypothetical 2610208m17rik protein0Direct
DBL homology domain (DH-domain)0Direct
(Phosphotyrosine protein) phosphatases II0Direct
A heparin-binding domain0Direct
FLJ32549 C-terminal domain-like0Direct
Heparin-binding domain from vascular endothelial growth factor0.000000000000003737Direct
Protein kinase-like (PK-like)0.00000000000009888Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.0000000000002381Direct
Transducin (heterotrimeric G protein), gamma chain0.00000000006291Direct
HMG-box0.0000000006696Direct
Growth factor receptor domain0.0000000007293Direct
Suppressor of Fused, N-terminal domain0.000000001184Direct
Regulatory factor Nef0.000000003491Direct
Rhodanese/Cell cycle control phosphatase0.000000004825Direct
Thyroglobulin type-1 domain0.000000004912Direct
Ras GEF0.00000001024Direct
DUSP-like0.00000002701Direct
Satiety factor CART (cocaine and amphetamine regulated transcript)0.0000000477Direct
Hedgehog/DD-peptidase0.00000006245Direct
Cysteine-rich domain0.0000001143Direct
Chitinase insertion domain0.0000002002Direct
SAP domain0.0000002666Direct
Frizzled cysteine-rich domain0.0000003097Direct
Second domain of FERM0.0000006964Direct
Cytokine0.0000009382Direct
N-terminal coiled coil domain from apc0.000001189Direct
Tumor suppressor gene product Apc0.000001189Direct
N-terminal domain of cbl (N-cbl)0.000001433Direct
Hedgehog/intein (Hint) domain0.000001517Direct
RING/U-box0.000002529Direct
MIT domain0.000007899Direct
SMAD MH1 domain0.00001064Direct
Calpain large subunit, middle domain (domain III)0.00003455Direct
B-box zinc-binding domain0.00004427Direct
SAND domain-like0.00005366Direct
KA1-like0.00005366Direct
Notch domain0.00005706Direct
SOCS box-like0.00006452Direct
Class II MHC-associated invariant chain ectoplasmic trimerization domain0.00006785Direct
PDZ domain-like0.0000805Direct
Nuclear receptor coactivator interlocking domain0.000113Direct
p53 tetramerization domain0.0001318Direct
Bromodomain0.0001344Direct
CAD & PB1 domains0.0001429Direct
AhpD-like0.0001623Direct
LDL receptor-like module0.0001853Direct
Bcl-2 inhibitors of programmed cell death0.0002108Direct
Snake toxin-like0.0005048Direct
Mitochondrial glycoprotein MAM33-like0.0005893Direct
Cu,Zn superoxide dismutase-like0.0006416Direct
Ricin B-like lectins0.000675Direct
FnI-like domain0.0006788Direct
Hsp90 co-chaperone CDC370.000737Direct
Cystine-knot cytokines0.0007568Direct
Prefoldin0.2731Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain1Inherited
Nqo5-like0.001594Inherited
Cyclophilin-like1Inherited
C-type lectin-like1Inherited
VHP, Villin headpiece domain0.96Inherited
SRCR-like0.1902Inherited
Tetraspanin0.07663Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.00257Inherited
alpha/beta-Hydrolases1Inherited
SAM/Pointed domain0.1368Inherited
lambda repressor-like DNA-binding domains0.37Inherited
Periplasmic binding protein-like II1Inherited
Periplasmic binding protein-like I1Inherited
L domain-like1Inherited
p53-like transcription factors0.01156Inherited
TSP-1 type 1 repeat0.05769Inherited
SH3-domain0.093Inherited
G protein-binding domain0.003083Inherited
RNA-binding domain, RBD1Inherited
ACT-like0.9236Inherited
Integrin alpha N-terminal domain0.6792Inherited
N-acetylmuramoyl-L-alanine amidase-like0.5792Inherited
ClpS-like0.05971Inherited
Rap/Ran-GAP0.03232Inherited
Skp1 dimerisation domain-like0.2406Inherited
Sema domain1Inherited
RGC domain-like0.003083Inherited
Moesin tail domain0.004132Inherited
beta-beta-alpha zinc fingers0.9673Inherited
HSP90 C-terminal domain0.4201Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
UBA-like0.04974Inherited
HSP20-like chaperones0.9995Inherited
Ribosomal protein S5 domain 2-like1Inherited
UBC-like0.9726Inherited
RL5-like0.03926Inherited
BRCT domain1Inherited
SWIB/MDM2 domain0.4703Inherited
post-AAA+ oligomerization domain-like0.6699Inherited
DNA clamp0.7989Inherited
POZ domain0.5092Inherited
PLC-like phosphodiesterases0.8432Inherited
CCCH zinc finger0.1957Inherited
Tudor/PWWP/MBT0.0139Inherited
ENTH/VHS domain0.005314Inherited
BPTI-like0.02315Inherited
Rhomboid-like0.1319Inherited
I/LWEQ domain0.2638Inherited
Thiolase-like1Inherited
Mitochondrial carrier1Inherited
Multidrug resistance efflux transporter EmrE1Inherited
Cystatin/monellin1Inherited
GTPase activation domain, GAP0.008128Inherited
L30e-like0.6341Inherited
E2F-DP heterodimerization region0.0203Inherited
"Winged helix" DNA-binding domain0.6766Inherited
Leucine zipper domain1Inherited
MIR domain1Inherited
Prion-like0.004223Inherited
t-snare proteins1Inherited
Nicotinic receptor ligand binding domain-like1Inherited
TNF receptor-like1Inherited
Inhibitor of apoptosis (IAP) repeat0.06452Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.3818Inherited
ADP-ribosylation0.822Inherited
HIT/MYND zinc finger-like0.5545Inherited
Kringle-like0.8384Inherited
Complement control module/SCR domain1Inherited
Kelch motif1Inherited
Ankyrin repeat0.05192Inherited
Fibrinogen C-terminal domain-like1Inherited
Fibrinogen coiled-coil and central regions0.2048Inherited
Phospholipase D/nuclease0.1271Inherited
Homodimeric domain of signal transducing histidine kinase0.8929Inherited
CheY-like1Inherited
DNA-binding domain0.07404Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
GST C-terminal domain-like1Inherited
FKBP-like0.01062Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.3571Inherited
Thioredoxin-like1Inherited
Acid proteases1Inherited
WW domain0.003503Inherited
Carbohydrate phosphatase0.02575Inherited
Cullin homology domain0.7896Inherited
Cullin repeat-like0.1722Inherited
Stathmin0.00854Inherited
Chromo domain-like0.3993Inherited
Plexin repeat1Inherited
Bet v1-like1Inherited
Histone-fold0.8291Inherited
14-3-3 protein0.1722Inherited
Spectrin repeat0.5097Inherited
Sec7 domain0.1625Inherited
Sialidases0.2543Inherited
Quinoprotein alcohol dehydrogenase-like0.03412Inherited
NAD kinase/diacylglycerol kinase-like0.2493Inherited
RUN domain-like0.2361Inherited
VPS9 domain0.6993Inherited
ArfGap/RecO-like zinc finger0.02028Inherited
FF domain0.04999Inherited
EF-hand0.0445Inherited
Voltage-gated potassium channels1Inherited
Calcium-dependent phosphotriesterase0.06971Inherited
SET domain0.7608Inherited
Cytochrome P4501Inherited
NAD(P)-linked oxidoreductase1Inherited
Lipocalins0.002394Inherited
ALDH-like1Inherited
Ypt/Rab-GAP domain of gyp1p0.1835Inherited
TPR-like1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Soluble quinoprotein glucose dehydrogenase0.04651Inherited
Multidrug efflux transporter AcrB transmembrane domain0.1217Inherited
Cysteine proteinases0.9753Inherited
ARM repeat0.01296Inherited
Serpins0.991Inherited
Calponin-homology domain, CH-domain0.1631Inherited
Tropomyosin1Inherited
Clavaminate synthase-like1Inherited
TIMP-like0.001487Inherited
Integrin domains0.2392Inherited
vWA-like1Inherited
Phosphoglycerate mutase-like0.01231Inherited
Trypsin-like serine proteases1Inherited
Terpenoid cyclases/Protein prenyltransferases0.8151Inherited
Alpha-macroglobulin receptor domain0.9059Inherited
Anaphylotoxins (complement system)1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Interleukin 8-like chemokines1Inherited
DHH phosphoesterases0.1347Inherited
HD-domain/PDEase-like1Inherited
Transducin (alpha subunit), insertion domain0.01338Inherited
Family A G protein-coupled receptor-like0.3247Inherited
cAMP-binding domain-like1Inherited
Homeodomain-like0.45Inherited
Phenylalanine zipper0.08669Inherited
Invertebrate chitin-binding proteins0.009532Inherited
Phospholipase A2, PLA20.3486Inherited
Lipoxigenase0.2878Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.3506Inherited
NAD-binding domain of HMG-CoA reductase0.05615Inherited
Substrate-binding domain of HMG-CoA reductase0.05615Inherited
FAT domain of focal adhesion kinase0.002738Inherited
DNase I-like0.3591Inherited
PP2C-like0.8431Inherited
(Trans)glycosidases1Inherited
STAT0.281Inherited
Transcription factor STAT-4 N-domain0.1625Inherited
Calcium ATPase, transduction domain A1Inherited
Calcium ATPase, transmembrane domain M1Inherited
AN1-like Zinc finger0.3238Inherited
4-helical cytokines0.5101Inherited
Orange domain-like0.06452Inherited
Arginase/deacetylase0.1875Inherited
HLH, helix-loop-helix DNA-binding domain0.6622Inherited
Cap-Gly domain0.3571Inherited
DhaL-like0.002799Inherited
DAK1/DegV-like0.01283Inherited
TB module/8-cys domain0.01546Inherited
CRAL/TRIO domain0.001145Inherited
beta-sandwich domain of Sec23/240.2356Inherited
SH2 domain1Inherited
DNA/RNA polymerases1Inherited
Toll/Interleukin receptor TIR domain1Inherited
Fibronectin type III0.004355Inherited
Radical SAM enzymes1Inherited
RCC1/BLIP-II0.2878Inherited
Activating enzymes of the ubiquitin-like proteins0.03094Inherited
Nuclear receptor ligand-binding domain0.7784Inherited
Cryptochrome/photolyase, N-terminal domain0.09197Inherited
Cryptochrome/photolyase FAD-binding domain0.09197Inherited
Chaperone J-domain1Inherited
DnaJ/Hsp40 cysteine-rich domain0.1088Inherited
HSP40/DnaJ peptide-binding domain0.1836Inherited
Hect, E3 ligase catalytic domain0.1691Inherited
WD40 repeat-like0.0375Inherited
GLA-domain1Inherited
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.2082Inherited
E set domains0.8236Inherited
PYP-like sensor domain (PAS domain)0.692Inherited
Concanavalin A-like lectins/glucanases0.01333Inherited
Spermadhesin, CUB domain0.8817Inherited
Composite domain of metallo-dependent hydrolases0.3963Inherited
Metallo-dependent hydrolases1Inherited
Galactose-binding domain-like0.4876Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.8425Inherited
Metallothionein0.015Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.001898Inherited
Aspartate/ornithine carbamoyltransferase0.006989Inherited
Carbamoyl phosphate synthetase, large subunit connection domain0.007513Inherited
Methylglyoxal synthase-like0.05847Inherited
PreATP-grasp domain0.911Inherited
Class I glutamine amidotransferase-like1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
FYVE/PHD zinc finger0.04545Inherited
SMAD/FHA domain0.1243Inherited
HAD-like1Inherited
FabD/lysophospholipase-like1Inherited
F-box domain0.8979Inherited
Alkaline phosphatase-like0.006279Inherited
RNI-like0.5518Inherited
PX domain0.954Inherited
Blood coagulation inhibitor (disintegrin)0.5335Inherited
LEM domain0.2543Inherited
Serine protease inhibitors0.5792Inherited
BAR/IMD domain-like0.5108Inherited
Kazal-type serine protease inhibitors0.05849Inherited
Putative DNA-binding domain0.006589Inherited
Acetyl-CoA synthetase-like1Inherited
GAS2 domain-like0.3689Inherited
UDP-glucose/GDP-mannose dehydrogenase C-terminal domain0.1347Inherited
WWE domain0.2382Inherited
Pseudo ankyrin repeat-like0.1958Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
YWTD domain0.02271Inherited
SPOC domain-like0.5293Inherited
PAH2 domain0.01002Inherited
BRK domain-like0.03664Inherited
Doublecortin (DC)0.3238Inherited
EGF/Laminin0.06748Inherited
Immunoglobulin1Inherited
Insulin-like0.5702Inherited
SAICAR synthase-like0.05108Inherited
ABC transporter transmembrane region1Inherited
Caspase-like0.2356Inherited
Troponin coil-coiled subunits0.04492Inherited
Metalloproteases ("zincins"), catalytic domain0.6114Inherited
GAF domain-like1Inherited
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0.002799Inherited
Proteasome activator0.006335Inherited
WRKY DNA-binding domain1Inherited
Gamma-glutamyl cyclotransferase-like0.3058Inherited
Hemopexin-like domain0.5822Inherited
PGBD-like0.9516Inherited
Rudiment single hybrid motif1Inherited
Tubby C-terminal domain-like0.1569Inherited
Integrin beta tail domain0.3571Inherited
C-terminal domain of PLC-beta0.5566Inherited
TRAF domain-like0.002429Inherited
TNF-like0.8567Inherited
Viral glycoprotein, central and dimerisation domains0.3486Inherited
Ran binding protein zinc finger-like0.01758Inherited
DEATH domain1Inherited
dsRNA-binding domain-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    90209,57850
  • 90209 - Ran binding protein zinc finger-like
  • 57850 - RING/U-box
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    116846,81383
  • 116846 - MIT domain
  • 81383 - F-box domain
  • 0Direct
    56491,109843
  • 56491 - A heparin-binding domain
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0Direct
    50370,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 0Direct
    47473,57997
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    48371,52087
  • 48371 - ARM repeat
  • 52087 - CRAL/TRIO domain
  • 0Direct
    48350,48371
  • 48350 - GTPase activation domain, GAP
  • 48371 - ARM repeat
  • 0Direct
    48726,57424
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 0Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    57424,48726
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 0Direct
    48670,48097
  • 48670 - Transducin (heterotrimeric G protein), gamma chain
  • 48097 - Regulator of G-protein signaling, RGS
  • 0Direct
    90229,63748
  • 90229 - CCCH zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    63763,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 0Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0Direct
    158548,160651
  • 158548 - FLJ32549 domain-like
  • 160651 - FLJ32549 C-terminal domain-like
  • 0Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 9.676e-16Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0.000000000000005554Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.0000000000000127Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0.00000000000002147Direct
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 0.00000000000002322Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0000000000002205Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.0000000000002381Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.00000000001149Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.00000000005576Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00000000006592Direct
    54236,90209
  • 54236 - Ubiquitin-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0000000001436Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.0000000001628Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.0000000001819Direct
    50729,48366
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.0000000003292Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000000007083Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.0000000008352Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.000000001001Direct
    49764,48452
  • 49764 - HSP20-like chaperones
  • 48452 - TPR-like
  • 0.00000000112Direct
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000001527Direct
    57184,82895
  • 57184 - Growth factor receptor domain
  • 82895 - TSP-1 type 1 repeat
  • 0.000000001749Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000000001967Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.000000007547Direct
    82199,48452
  • 82199 - SET domain
  • 48452 - TPR-like
  • 0.000000008099Direct
    54277,57850
  • 54277 - CAD & PB1 domains
  • 57850 - RING/U-box
  • 0.00000001824Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00000004288Direct
    68906,57850
  • 68906 - SAP domain
  • 57850 - RING/U-box
  • 0.00000004288Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.00000004513Direct
    47113,48065
  • 47113 - Histone-fold
  • 48065 - DBL homology domain (DH-domain)
  • 0.0000000477Direct
    48366,57889
  • 48366 - Ras GEF
  • 57889 - Cysteine-rich domain
  • 0.0000000477Direct
    47473,57603
  • 47473 - EF-hand
  • 57603 - FnI-like domain
  • 0.00000007277Direct
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.00000008376Direct
    81296,48403
  • 81296 - E set domains
  • 48403 - Ankyrin repeat
  • 0.00000008376Direct
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.0000001211Direct
    57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0000001763Direct
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.0000001995Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.0000002002Direct
    57610,47473
  • 57610 - Thyroglobulin type-1 domain
  • 47473 - EF-hand
  • 0.0000002177Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0.0000002256Direct
    47370,63748
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.0000004446Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0000008206Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.0000008206Direct
    50044,140741
  • 50044 - SH3-domain
  • 140741 - RUN domain-like
  • 0.0000008467Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.0000008467Direct
    81995,49417
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 0.0000008467Direct
    56112,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 0.00000102Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.000001189Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.000001433Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.000001433Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000001443Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000002154Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.000002364Direct
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.000003258Direct
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
  • 0.000003258Direct
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.000005626Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.000009213Direct
    50939,50939
  • 50939 - Sialidases
  • 50939 - Sialidases
  • 0.0000137Direct
    50044,53335
  • 50044 - SH3-domain
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.0000137Direct
    47769,56399
  • 47769 - SAM/Pointed domain
  • 56399 - ADP-ribosylation
  • 0.0000137Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000145Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.00001483Direct
    57850,54928
  • 57850 - RING/U-box
  • 54928 - RNA-binding domain, RBD
  • 0.0000197Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.00002226Direct
    116846,116846
  • 116846 - MIT domain
  • 116846 - MIT domain
  • 0.00002329Direct
    50044,50729
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0.00003303Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.00003816Direct
    48726,49899
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005366Direct
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.00005706Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00006452Direct
    54695,50978
  • 54695 - POZ domain
  • 50978 - WD40 repeat-like
  • 0.00006453Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.00007822Direct
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.00008324Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0.0001217Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.0001318Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.0001439Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.0001659Direct
    56300,47473
  • 56300 - Metallo-dependent phosphatases
  • 47473 - EF-hand
  • 0.0001733Direct
    57903,50729
  • 57903 - FYVE/PHD zinc finger
  • 50729 - PH domain-like
  • 0.0001733Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.0001935Direct
    50729,57903
  • 50729 - PH domain-like
  • 57903 - FYVE/PHD zinc finger
  • 0.0002114Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.0002114Direct
    51445,51445
  • 51445 - (Trans)glycosidases
  • 51445 - (Trans)glycosidases
  • 0.0002114Direct
    82549,101473
  • 82549 - DAK1/DegV-like
  • 101473 - DhaL-like
  • 0.0002162Direct
    52335,51556
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.0002162Direct
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0003359Direct
    48305,57610
  • 48305 - Class II MHC-associated invariant chain ectoplasmic trimerization domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0003672Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.0004335Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0004981Direct
    56112,103243
  • 56112 - Protein kinase-like (PK-like)
  • 103243 - KA1-like
  • 0.0005558Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0009802Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 1Inherited
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.3486Inherited
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.3571Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 1Inherited
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.001408Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.3285Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.5254Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.001455Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.001455Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.001708Inherited
    52540,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 0.008136Inherited
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.2291Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 1Inherited
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001122Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.3571Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    47986,56112
  • 47986 - DEATH domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.001122Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.5222Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.836Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0215Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01002Inherited
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0.2638Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.652Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.9059Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.1003Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.2889Inherited
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.5719Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.8865Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.156Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.849Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.01449Inherited
    50044,48350
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 1Inherited
    48350,55550
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 1Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 1Inherited
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05641Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.06452Inherited
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.08669Inherited
    57581,100895
  • 57581 - TB module/8-cys domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0.2048Inherited
    51206,56112
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.8611Inherited
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.004823Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    52172,46689
  • 52172 - CheY-like
  • 46689 - Homeodomain-like
  • 0.4699Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 1Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.05641Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.2889Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.03664Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.8151Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.006496Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.006496Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004844Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.2082Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.7896Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.001772Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.7024Inherited
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0.0101Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.152Inherited
    52087,48350
  • 52087 - CRAL/TRIO domain
  • 48350 - GTPase activation domain, GAP
  • 0.001734Inherited
    103657,48350
  • 103657 - BAR/IMD domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.2048Inherited
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.06921Inherited
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.4699Inherited
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.1332Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.152Inherited
    57863,50729
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 0.2048Inherited
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.2543Inherited
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.3371Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.2878Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.3549Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.8584Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.1118Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00131Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.3316Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.01648Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 1Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.04491Inherited
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0.08669Inherited
    48403,158235
  • 48403 - Ankyrin repeat
  • 158235 - SOCS box-like
  • 0.05971Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.8294Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.2746Inherited
    48239,49410
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 49410 - Alpha-macroglobulin receptor domain
  • 0.1302Inherited
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.9924Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.2082Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01338Inherited
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.01546Inherited
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.02382Inherited
    56487,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0.1302Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.198Inherited
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0.2048Inherited
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.2878Inherited
    55035,56542
  • 55035 - NAD-binding domain of HMG-CoA reductase
  • 56542 - Substrate-binding domain of HMG-CoA reductase
  • 0.05615Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.4985Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.281Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.281Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.1625Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    47986,52200
  • 47986 - DEATH domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.1332Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.06452Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.7115Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.04794Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.707Inherited
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0.4566Inherited
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.01283Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.01113Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.01113Inherited
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.01821Inherited
    57581,57581
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 0.02094Inherited
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.001148Inherited
    50729,48350
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.001455Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01546Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0.167Inherited
    50978,57903
  • 50978 - WD40 repeat-like
  • 57903 - FYVE/PHD zinc finger
  • 0.001122Inherited
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0.09197Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.4315Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.1003Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.2384Inherited
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.2416Inherited
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.08669Inherited
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.05641Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.002156Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.9924Inherited
    50044,56112
  • 50044 - SH3-domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.03664Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00385Inherited
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.4436Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03232Inherited
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.2082Inherited
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.7896Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.08976Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.004698Inherited
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.006496Inherited
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.7558Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.7743Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.01657Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1271Inherited
    52317,52440
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.001205Inherited
    52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 0.001594Inherited
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.006487Inherited
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.007513Inherited
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.007513Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.771Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.004061Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.02131Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.03113Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.003366Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1013Inherited
    81383,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 0.2104Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.04491Inherited
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0.08669Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.7512Inherited
    100895,50494
  • 100895 - Kazal-type serine protease inhibitors
  • 50494 - Trypsin-like serine proteases
  • 0.05641Inherited
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0.05641Inherited
    50494,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 0.1302Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.003043Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.2543Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.633Inherited
    48179,52413
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 52413 - UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
  • 0.1255Inherited
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0.04548Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 1Inherited
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.03664Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.1561Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.2746Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2839Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.3486Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.1078Inherited
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.3486Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.04492Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.1347Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.1581Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.07163Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 1Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    55781,47384
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0.08669Inherited
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 1Inherited
    57196,49785
  • 57196 - EGF/Laminin
  • 49785 - Galactose-binding domain-like
  • 0.001734Inherited
    63825,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 0.006335Inherited
    47473,90257
  • 47473 - EF-hand
  • 90257 - Myosin rod fragments
  • 0.3486Inherited
    159034,57850
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 0.001734Inherited
    57850,159034
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0.001734Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.4315Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.9516Inherited
    54534,47473
  • 54534 - FKBP-like
  • 47473 - EF-hand
  • 0.002541Inherited
    53448,50370
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 50370 - Ricin B-like lectins
  • 0.2453Inherited
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 1Inherited
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.02217Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.3571Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.5776Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.9539Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 1Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 1Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.008685Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.01203Inherited
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0.1332Inherited
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0.3486Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.1949Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0948Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.006496Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.2356Inherited
    48726,52200
  • 48726 - Immunoglobulin
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.6993Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.4796Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57424,56487,57424
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56487,57424,56487
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    48726,49899,57196
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    57424,48726,57424
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 0Direct
    48350,48371,52087
  • 48350 - GTPase activation domain, GAP
  • 48371 - ARM repeat
  • 52087 - CRAL/TRIO domain
  • 0Direct
    50370,56436,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    47473,47473,57997
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0Direct
    63763,47095,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    48726,57424,57424
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    90209,57850,57850
  • 90209 - Ran binding protein zinc finger-like
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    57424,57424,48726
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 0Direct
    54236,90209,57850
  • 54236 - Ubiquitin-like
  • 90209 - Ran binding protein zinc finger-like
  • 57850 - RING/U-box
  • 0Direct
    81995,49417,81296
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0.000000000000001898Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.000000000004177Direct
    47031,50729,55550
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.000000000007782Direct
    81296,48403,52540
  • 81296 - E set domains
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000007782Direct
    56436,56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0000000001049Direct
    48065,50729,48366
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.0000000003292Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000000001195Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00000001485Direct
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00000001641Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.00000001681Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00000004288Direct
    57903,47370,63748
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.00000004468Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000004509Direct
    100895,47473,57603
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57603 - FnI-like domain
  • 0.00000007277Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000002666Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0000008206Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0000008206Direct
    48403,47769,56399
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 56399 - ADP-ribosylation
  • 0.0000008467Direct
    48403,48403,47769
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0.0000008467Direct
    47113,48065,50729
  • 47113 - Histone-fold
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0000008467Direct
    56112,116846,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 116846 - MIT domain
  • 0.00000102Direct
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.000001189Direct
    50729,49562,48350
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.000002364Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000004896Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00001432Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00002134Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00002172Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.00002654Direct
    48726,48726,49899
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005366Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00006453Direct
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.00008324Direct
    52335,51556,51338
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0001004Direct
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.000123Direct
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.0001291Direct
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001291Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001318Direct
    50729,57903,50729
  • 50729 - PH domain-like
  • 57903 - FYVE/PHD zinc finger
  • 50729 - PH domain-like
  • 0.0001733Direct
    48065,50729,57903
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 57903 - FYVE/PHD zinc finger
  • 0.0001733Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0001977Direct
    56059,52335,51556
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.0002162Direct
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0003359Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.0003672Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0004791Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0004981Direct
    82199,57667,57667
  • 82199 - SET domain
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.000737Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.000737Direct
    52021,52317,52440
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.0009455Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0009493Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 1Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.9075Inherited
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.3486Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3285Inherited
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.08669Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.001455Inherited
    52540,48452,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.001122Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.08669Inherited
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001122Inherited
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001122Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.3571Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01002Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01002Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.08497Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.1003Inherited
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.5719Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.8865Inherited
    50044,48350,55550
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 1Inherited
    57581,100895,100895
  • 57581 - TB module/8-cys domain
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.2048Inherited
    51206,51206,56112
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.8611Inherited
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.001734Inherited
    49854,57535,49854
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.004823Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.05641Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.2082Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.001148Inherited
    50729,50729,48350
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.1332Inherited
    50729,50729,57863
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.1332Inherited
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.1332Inherited
    50729,57863,50729
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 0.2048Inherited
    57863,50729,50729
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.2048Inherited
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.2543Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.2878Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.3549Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.989Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002738Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.8014Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.03113Inherited
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.3849Inherited
    48239,49410,50242
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.183Inherited
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.02382Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.281Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1625Inherited
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.002245Inherited
    47986,47986,52540
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8611Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.01477Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.3576Inherited
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.007513Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.02624Inherited
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.03002Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.03022Inherited
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.006167Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00996Inherited
    57581,57184,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.04452Inherited
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.06253Inherited
    57581,57581,57184
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.004844Inherited
    57581,57184,57196
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00854Inherited
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.01283Inherited
    57184,57581,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 0.016Inherited
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.02094Inherited
    57581,57196,57184
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02375Inherited
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.04125Inherited
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.001148Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02382Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0878Inherited
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.7989Inherited
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.08669Inherited
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.08669Inherited
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 1Inherited
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1332Inherited
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2048Inherited
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.06452Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03664Inherited
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.7045Inherited
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.006496Inherited
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.6513Inherited
    52317,52440,56059
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.001205Inherited
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.006487Inherited
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.006487Inherited
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.007513Inherited
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.007513Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.4201Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00854Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.002304Inherited
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.006496Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03113Inherited
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.08497Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001812Inherited
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0.08669Inherited
    100895,50494,50156
  • 100895 - Kazal-type serine protease inhibitors
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 0.05641Inherited
    57184,100895,50494
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 50494 - Trypsin-like serine proteases
  • 0.05641Inherited
    51735,48179,52413
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 52413 - UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
  • 0.1255Inherited
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.03664Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.03664Inherited
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.03664Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2746Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.2954Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.3058Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.183Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.01779Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    55781,47384,55874
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.2048Inherited
    57184,57603,82895
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.2048Inherited
    47473,47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.1302Inherited
    159034,57850,159034
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0.001734Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.4315Inherited
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 1Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.4484Inherited
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.5141Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 1Inherited
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.03094Inherited
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.0101Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0215Inherited
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.01002Inherited
    55550,50044,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003563Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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