SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Biological Process (BP): negative regulation of organelle organization

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + 4:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + 3:   negative regulation of biological process [GO:0048519] <52>(72|76) (445|449|253)
+ + + 3:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + 2:   negative regulation of cellular process [GO:0048523] <65>(61|62) (404|394|222)
+ + 2:   regulation of cellular component organization [GO:0051128] <52>(35|32) (311|310|174)
+ 1:   negative regulation of cellular component organization [GO:0051129] <46>(13|10) (141|103|53)
+ 1:   regulation of organelle organization [GO:0033043] <27>(20|20) (194|151|67)
0:   negative regulation of organelle organization [GO:0010639] <21>(9|8) (86|49|24)
- 1:   negative regulation of cytoskeleton organization [GO:0051494] <17>(5|5) (42|23|15)
- 1:   negative regulation of organelle assembly [GO:1902116] <13>(0|0) (3|0|0)
- 1:   negative regulation of chromosome organization [GO:2001251] <8>(3|2) (35|22|9)
- 1:   negative regulation of mitochondrion organization [GO:0010823] <8>(1|1) (7|3|0)
- 1:   negative regulation of vesicle fusion [GO:0031339] <4>(0|0) (1|0|0)
- 1:   negative regulation of nuclear division [GO:0051784] <2>(2|2) (12|5|1)
- 1:   negative regulation of endosome organization [GO:1904979] <1>(0|0) (0|0|0)
- 1:   negative regulation of cargo loading into COPII-coated vesicle [GO:1901303](0|0) (0|0|0)
- 1:   negative regulation of chloroplast fission [GO:1905193](0|0) (0|0|0)
- 1:   negative regulation of endoplasmic reticulum tubular network organization [GO:1903372](0|0) (0|0|0)
- 1:   negative regulation of intraciliary anterograde transport [GO:1905797](0|0) (0|0|0)
- 1:   negative regulation of intraciliary retrograde transport [GO:1905800](0|0) (0|0|0)
- 1:   negative regulation of lysosome organization [GO:1905672](0|0) (0|0|0)
- 1:   negative regulation of melanosome organization [GO:1903057](0|0) (0|0|0)
- 1:   negative regulation of mitotic nuclear envelope disassembly [GO:1905558](0|0) (0|0|0)
- 1:   negative regulation of phagosome maturation [GO:1905163](0|0) (0|0|0)
- 1:   negative regulation of postsynaptic density organization [GO:1905875](0|0) (0|0|0)
- 1:   negative regulation of secretory granule organization [GO:1904410](0|0) (0|0|0)
- 1:   negative regulation of spermatid nuclear differentiation [GO:0045701](0|0) (0|0|0)
- 1:   negative regulation of synaptic vesicle lumen acidification [GO:1901547](0|0) (0|0|0)
- 1:   negative regulation of vacuole fusion, non-autophagic [GO:0061192](0|0) (0|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Calponin-homology domain, CH-domain0.00000078730Direct
Cytidine deaminase-like00.000000003003Direct
Profilin (actin-binding protein)0.000082590.00008616Direct
Stathmin0.0007870.0008513Direct
Subunits of heterodimeric actin filament capping protein Capz00Direct
The spindle assembly checkpoint protein mad20.0000026450.000000002Direct
Mitochondrial carrier0.00068370.06208Inherited
WD40 repeat-like0.28870.3298Inherited
EF-hand0.14910.0002775Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Calponin-homology domain, CH-domain0.00000050820Direct
Capz alpha-1 subunit0.00000000063640.0000000009202Direct
Capz beta-1 subunit00.0000000000001267Direct
Profilin (actin-binding protein)0.00005270.00006897Direct
Stathmin0.00055170.0007004Direct
The spindle assembly checkpoint protein mad20.0000016510.00000000004049Direct
Mitochondrial carrier0.00090150.06525Inherited
Cell cycle arrest protein BUB30.0091860.0114Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAS2 domain-like0Direct
Plakin repeat0Direct
Calponin-homology domain, CH-domain0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
Actin depolymerizing proteins0Direct
EB1 dimerisation domain-like0.000000000000001898Direct
Spectrin repeat0.000000000001846Direct
Clavaminate synthase-like0.00000000001919Direct
The spindle assembly checkpoint protein mad20.000000001184Direct
Cytidine deaminase-like0.000000001786Direct
N-terminal coiled coil domain from apc0.00000002645Direct
Tumor suppressor gene product Apc0.00000002645Direct
HR1 repeat0.0000001177Direct
Insulin-like0.000000146Direct
Type II DNA topoisomerase0.0000007959Direct
FYVE/PHD zinc finger0.000001429Direct
Telomeric repeat binding factor (TRF) dimerisation domain0.000005385Direct
VHP, Villin headpiece domain0.00000582Direct
RuvA domain 2-like0.00001865Direct
FKBP-like0.00003352Direct
Profilin (actin-binding protein)0.00005877Direct
AraD/HMP-PK domain-like0.000062Direct
WWE domain0.0001042Direct
Restriction endonuclease-like0.0001685Direct
ARID-like0.0001891Direct
EF-hand0.0001931Direct
Chromo domain-like0.0004651Direct
Stathmin0.0006038Direct
ADP-ribosylation0.01678Inherited
Polo-box domain0.6266Inherited
Kelch motif0.003599Inherited
POZ domain0.303Inherited
SMAD/FHA domain0.0115Inherited
Acyl-CoA N-acyltransferases (Nat)0.3572Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1534Inherited
Ribosomal protein S5 domain 2-like0.2544Inherited
PABC (PABP) domain0.005754Inherited
Hect, E3 ligase catalytic domain0.01013Inherited
RCC1/BLIP-II0.3874Inherited
Arginase/deacetylase0.07909Inherited
TPR-like0.8014Inherited
L domain-like1Inherited
Mitochondrial carrier0.04846Inherited
Thiolase-like0.06456Inherited
Multidrug resistance efflux transporter EmrE0.1599Inherited
Cyclophilin-like0.03548Inherited
Tex N-terminal region-like0.001522Inherited
Nucleic acid-binding proteins0.02694Inherited
SH2 domain1Inherited
Cystine-knot cytokines0.05439Inherited
RNI-like0.3274Inherited
Moesin tail domain0.133Inherited
SAM/Pointed domain0.1855Inherited
C-terminal, gelsolin-like domain of Sec23/240.00113Inherited
DNase I-like0.00113Inherited
Thyroglobulin type-1 domain0.01013Inherited
SH3-domain0.4154Inherited
BAR/IMD domain-like0.4628Inherited
Formin homology 2 domain (FH2 domain)1Inherited
Cyclin-like0.1865Inherited
Growth factor receptor domain1Inherited
F-box domain0.3142Inherited
RING/U-box0.4434Inherited
Bcl-2 inhibitors of programmed cell death0.1291Inherited
Protein kinase-like (PK-like)0.8434Inherited
Cysteine-rich DNA binding domain, (DM domain)0.001522Inherited
PDZ domain-like1Inherited
ARM repeat0.002759Inherited
WD40 repeat-like0.2744Inherited
Metallo-dependent phosphatases0.09406Inherited
Ankyrin repeat0.004024Inherited
GTPase activation domain, GAP1Inherited
BRCT domain0.03175Inherited
Periplasmic binding protein-like I0.3239Inherited
Cap-Gly domain0.109Inherited
Quinoprotein alcohol dehydrogenase-like0.2536Inherited
Cytokine0.1898Inherited
DBL homology domain (DH-domain)1Inherited
Homeodomain-like0.2865Inherited
Tudor/PWWP/MBT0.003171Inherited
Ribonuclease H-like0.2995Inherited
Sec7 domain0.005706Inherited
Second domain of FERM0.3274Inherited
PH domain-like1Inherited
Ubiquitin-like0.7413Inherited
B-box zinc-binding domain0.03082Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 9.676e-16Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000000003737Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.000000000001531Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.00000000000321Direct
    48403,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 0.000000000008572Direct
    48371,117839
  • 48371 - ARM repeat
  • 117839 - WWE domain
  • 0.00000000001132Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000000237Direct
    50249,55550
  • 50249 - Nucleic acid-binding proteins
  • 55550 - SH2 domain
  • 0.000000002175Direct
    63570,56204
  • 63570 - PABC (PABP) domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0000000285Direct
    49879,57850
  • 49879 - SMAD/FHA domain
  • 57850 - RING/U-box
  • 0.0000000285Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.00000004214Direct
    54211,56719
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.00000004519Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.00000008219Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000001177Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0000001177Direct
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.000001257Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.000001792Direct
    47781,50249
  • 47781 - RuvA domain 2-like
  • 50249 - Nucleic acid-binding proteins
  • 0.000008984Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.00001101Direct
    47781,47781
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
  • 0.00001406Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0.000027Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.00008324Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.1305Inherited
    63748,57903
  • 63748 - Tudor/PWWP/MBT
  • 57903 - FYVE/PHD zinc finger
  • 0.001961Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001324Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.001961Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.006471Inherited
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.001522Inherited
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.006471Inherited
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.02087Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.00302Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.3554Inherited
    53098,47781
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 0.001522Inherited
    158832,53098
  • 158832 - Tex N-terminal region-like
  • 53098 - Ribonuclease H-like
  • 0.001522Inherited
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.005754Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.5637Inherited
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.004634Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.06025Inherited
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.04387Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1Inherited
    46774,51197
  • 46774 - ARID-like
  • 51197 - Clavaminate synthase-like
  • 0.006471Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0629Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.4127Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.001961Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    48403,74924,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000000003737Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000000000000007352Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000000237Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000000237Direct
    54534,54534,48452
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.00000001097Direct
    55874,54211,56719
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.00000003299Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.00000004214Direct
    47781,50249,55550
  • 47781 - RuvA domain 2-like
  • 50249 - Nucleic acid-binding proteins
  • 55550 - SH2 domain
  • 0.00000008013Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.0000004602Direct
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.00000688Direct
    47781,47781,50249
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
  • 50249 - Nucleic acid-binding proteins
  • 0.000008984Direct
    53098,47781,47781
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
  • 0.00001132Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.00008324Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0001042Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0003992Direct
    63748,57903,57903
  • 63748 - Tudor/PWWP/MBT
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.001961Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001186Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001324Inherited
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.001522Inherited
    158832,53098,47781
  • 158832 - Tex N-terminal region-like
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 0.001522Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.5131Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)