SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): sexual reproduction

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + 2:   biological_process [GO:0008150] <24>
+ + 2:   multi-organism process [GO:0051704] <17>(58|54) (383|283|130)
+ + 2:   reproductive process [GO:0022414] <78>(33|37) (289|181|83)
+ 1:   multi-organism reproductive process [GO:0044703] <15>(14|15) (214|138|64)
+ 1:   reproduction [GO:0000003] <6>(37|41) (304|189|85)
0:   sexual reproduction [GO:0019953] <6>(13|15) (198|125|52)
- 1:   conjugation with cellular fusion [GO:0000747] <10>(0|0) (14|3|1)
- 1:   gamete generation [GO:0007276] <8>(8|9) (161|108|44)
- 1:   sexual sporulation [GO:0034293] <4>(0|0) (9|1|0)
- 1:   fertilization [GO:0009566] <3>(4|4) (34|13|6)
- 1:   mating [GO:0007618] <2>(1|1) (24|6|1)
- 1:   sporocarp development involved in sexual reproduction [GO:0000909] <1>(1|1) (1|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cadherin-like0.0000000000082290.0002406Direct
Defensin-like00.000000002932Direct
Fertilization protein00Direct
Cystine-knot cytokines0.091571Inherited
Phospholipase D/nuclease0.0000000000000091160.01281Inherited
NAD(P)-binding Rossmann-fold domains0.60181Inherited
Trypsin-like serine proteases0.80470.4833Inherited
Lysozyme-like0.000041230.08485Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.0043960.04165Inherited
Terpenoid synthases0.0019120.4665Inherited
Metalloproteases ("zincins"), catalytic domain0.090140.2436Inherited
Cu,Zn superoxide dismutase-like0.020240.1979Inherited
WD40 repeat-like0.29290.1952Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
C-type lysozyme0.0000001690.000003837Direct
Defensin00.0000000000008278Direct
Fertilization protein00Direct
Nuclease0.0000000000000011680.00000000002608Direct
Protein kinases, catalytic subunit0.000059920.0003308Direct
Nucleosome core histones0.0041270.01761Inherited
Gonadodropin/Follitropin0.049970.1345Inherited
Tyrosine-dependent oxidoreductases0.6781Inherited
Eukaryotic proteases0.77630.3824Inherited
Isoprenyl diphosphate synthases0.00053320.02968Inherited
Astacin0.067960.02122Inherited
AlkB-like0.00000013820.01181Inherited
Cu,Zn superoxide dismutase-like0.019670.1847Inherited
G proteins0.036780.7678Inherited
WD40-repeat0.35990.2487Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Pseudo ankyrin repeat-like0Direct
Fertilization protein0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
RNA-binding domain, RBD0.00000000000006066Direct
Tudor/PWWP/MBT0.000000000006754Direct
BAR/IMD domain-like0.00000000003585Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.00000000005168Direct
A heparin-binding domain0.0000000002181Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.0000000007683Direct
HR1 repeat0.0000000007683Direct
Defensin-like0.000000001743Direct
Crisp domain-like0.000000002383Direct
PDZ domain-like0.00000001813Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.0000001236Direct
Stathmin0.0000001781Direct
Ankyrin repeat0.000000229Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0.0000004583Direct
G protein-binding domain0.0000005087Direct
SAM/Pointed domain0.0000005473Direct
Kix domain of CBP (creb binding protein)0.000001131Direct
MAST3 pre-PK domain-like0.000001255Direct
SH3-domain0.000002118Direct
Spectrin repeat0.000002845Direct
YWTD domain0.000003765Direct
ACT-like0.000004058Direct
dsRNA-binding domain-like0.00001079Direct
PAZ domain0.0000265Direct
Phenylalanine zipper0.00003224Direct
Nucleoplasmin-like core domain0.00003891Direct
Chromo domain-like0.00004736Direct
Calponin-homology domain, CH-domain0.00007239Direct
ABC transporter transmembrane region0.00007251Direct
Ribonuclease H-like0.0001052Direct
A middle domain of Talin 10.0001519Direct
Cadherin-like0.0001669Direct
beta-sandwich domain of Sec23/240.0002106Direct
(Phosphotyrosine protein) phosphatases II0.0002407Direct
PH domain-like0.0003209Direct
Tetraspanin0.0003381Direct
Colipase-like0.0004127Direct
FYVE/PHD zinc finger0.0004146Direct
POZ domain0.0005232Direct
GroEL apical domain-like0.0008067Direct
Cysteine-rich domain0.0008742Direct
(Trans)glycosidases1Inherited
L domain-like1Inherited
DNase I-like0.575Inherited
EF-hand0.4022Inherited
Insulin-like0.6869Inherited
Rhomboid-like0.07733Inherited
eIF4e-like0.201Inherited
Rap/Ran-GAP0.05863Inherited
E2F-DP heterodimerization region0.05863Inherited
Activating enzymes of the ubiquitin-like proteins0.0619Inherited
ARID-like0.001455Inherited
"Winged helix" DNA-binding domain0.3018Inherited
RNase III domain-like0.1562Inherited
F-box domain1Inherited
WD40 repeat-like0.1583Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
Nuclear receptor coactivator interlocking domain0.3374Inherited
PYP-like sensor domain (PAS domain)0.1274Inherited
beta-beta-alpha zinc fingers0.775Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Caspase-like0.5255Inherited
Voltage-gated potassium channels0.6382Inherited
Ran binding protein zinc finger-like0.5058Inherited
HIT/MYND zinc finger-like0.04279Inherited
FKBP-like0.2172Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.03212Inherited
Galactose-binding domain-like1Inherited
Subtilisin-like0.3362Inherited
Protease propeptides/inhibitors0.2446Inherited
Metalloproteases ("zincins"), catalytic domain0.1996Inherited
GroEL-intermediate domain like0.001965Inherited
GroEL equatorial domain-like0.002149Inherited
Trefoil0.007048Inherited
Cystatin/monellin0.3624Inherited
Blood coagulation inhibitor (disintegrin)0.01947Inherited
lambda repressor-like DNA-binding domains1Inherited
Riboflavin synthase domain-like0.4755Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.5063Inherited
Spermadhesin, CUB domain0.6664Inherited
Hemopexin-like domain0.9595Inherited
PGBD-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Protein kinase-like (PK-like)0.001157Inherited
KA1-like0.3771Inherited
TAZ domain0.2324Inherited
SMAD MH1 domain0.2141Inherited
Snake toxin-like0.01697Inherited
Heme-dependent peroxidases0.3026Inherited
Glycoside hydrolase/deacetylase0.7888Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
PX domain0.7345Inherited
p53-like transcription factors0.7293Inherited
SAICAR synthase-like0.6613Inherited
alpha/beta-Hydrolases1Inherited
PABC (PABP) domain0.03229Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.5792Inherited
NAD kinase/diacylglycerol kinase-like0.6347Inherited
Regulator of G-protein signaling, RGS0.02155Inherited
Terpenoid synthases0.3951Inherited
PR-1-like0.5325Inherited
UBA-like0.4194Inherited
C-type lectin-like1Inherited
Nuclear receptor ligand-binding domain1Inherited
Family A G protein-coupled receptor-like0.5342Inherited
BPTI-like0.9858Inherited
HD-domain/PDEase-like0.7604Inherited
Lysozyme-like0.06687Inherited
Immunoglobulin0.5045Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.002349Inherited
PLC-like phosphodiesterases0.0864Inherited
C-terminal domain of PLC-beta0.2343Inherited
t-snare proteins0.005854Inherited
Bromodomain0.01496Inherited
Homeodomain-like1Inherited
Trypsin-like serine proteases0.4102Inherited
Kazal-type serine protease inhibitors0.5565Inherited
Second domain of FERM0.2354Inherited
L27 domain0.3374Inherited
SOCS box-like0.2521Inherited
Toll/Interleukin receptor TIR domain0.7723Inherited
SAP domain0.4079Inherited
Actin depolymerizing proteins0.4079Inherited
CRAL/TRIO domain0.5565Inherited
TPR-like0.7479Inherited
Cullin homology domain0.4531Inherited
DBL homology domain (DH-domain)0.2784Inherited
GAS2 domain-like0.01492Inherited
DNA mismatch repair protein MutL0.6613Inherited
A DNA-binding domain in eukaryotic transcription factors0.2324Inherited
EGF/Laminin0.05024Inherited
Cystine-knot cytokines1Inherited
C-terminal domain of adenylylcyclase associated protein0.1062Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.1062Inherited
SH2 domain0.02066Inherited
alpha-catenin/vinculin-like0.06836Inherited
I/LWEQ domain0.03229Inherited
N-terminal domain of cbl (N-cbl)0.1062Inherited
Ypt/Rab-GAP domain of gyp1p0.004504Inherited
DNA topoisomerase IV, alpha subunit0.9595Inherited
Chaperone J-domain0.608Inherited
Cysteine proteinases1Inherited
Histone-fold0.3721Inherited
RING/U-box0.7742Inherited
ARM repeat0.403Inherited
Oxysterol-binding protein-like0.01763Inherited
Nucleoside diphosphate kinase, NDK0.1964Inherited
UBC-like0.6041Inherited
Succinyl-CoA synthetase domains0.09624Inherited
Glutathione synthetase ATP-binding domain-like0.9131Inherited
Multidrug efflux transporter AcrB transmembrane domain0.852Inherited
P-loop containing nucleoside triphosphate hydrolases0.1513Inherited
Eukaryotic type KH-domain (KH-domain type I)0.003074Inherited
Staphylococcal nuclease0.02104Inherited
NAP-like0.03229Inherited
BRCA2 helical domain0.03229Inherited
BRCA2 tower domain0.03229Inherited
Cu,Zn superoxide dismutase-like0.1607Inherited
Cysteine-rich DNA binding domain, (DM domain)0.9091Inherited
Nucleotide cyclase0.1009Inherited
BRK domain-like0.003026Inherited
Phospholipase D/nuclease0.00957Inherited
Myosin S1 fragment, N-terminal domain0.1113Inherited
HMG-box0.002484Inherited
Phospholipase A2, PLA20.3374Inherited
SpoIIaa-like0.009773Inherited
Inhibitor of apoptosis (IAP) repeat0.01742Inherited
The spindle assembly checkpoint protein mad20.4995Inherited
Cullin repeat-like0.4995Inherited
Formin homology 2 domain (FH2 domain)0.00241Inherited
Fibronectin type III0.1847Inherited
SMAD/FHA domain0.3769Inherited
Subunits of heterodimeric actin filament capping protein Capz0.003156Inherited
TSP-1 type 1 repeat0.4666Inherited
BRCT domain0.04729Inherited
Lamin A/C globular tail domain0.002492Inherited
Tubulin C-terminal domain-like1Inherited
Tubulin nucleotide-binding domain-like1Inherited
Polo-box domain0.7723Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
Ribosomal protein S5 domain 2-like1Inherited
Bet v1-like1Inherited
Cyclin-like0.6796Inherited
Kelch motif0.3Inherited
Integrin alpha N-terminal domain0.5425Inherited
Integrin domains0.9091Inherited
Ubiquitin-like0.004993Inherited
Transducin (alpha subunit), insertion domain0.2238Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.282Inherited
Acid proteases0.303Inherited
Calcium ATPase, transduction domain A0.5272Inherited
Calcium ATPase, transmembrane domain M0.6025Inherited
HAD-like1Inherited
CAD & PB1 domains0.9915Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    47769,140860
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.000000000000009141Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.000000000002254Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.00000000005168Direct
    48403,140860
  • 48403 - Ankyrin repeat
  • 140860 - Pseudo ankyrin repeat-like
  • 0.0000000001647Direct
    55797,57546
  • 55797 - PR-1-like
  • 57546 - Crisp domain-like
  • 0.0000000005354Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00000001704Direct
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.0000001236Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001589Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000001984Direct
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000004815Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0000005996Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0.0000008007Direct
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.0000008514Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0.000001035Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000001118Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.000004618Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.000005028Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0000088Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.0000127Direct
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0.00001404Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.00001767Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00003171Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.0000655Direct
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.0000881Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.0000881Direct
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.0001519Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0002087Direct
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0002467Direct
    57190,57190
  • 57190 - Colipase-like
  • 57190 - Colipase-like
  • 0.0002987Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0.0003793Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.0005103Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.0005884Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0006653Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0006694Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0007266Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.00089Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1773Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.05863Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.08114Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.05863Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.6794Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1607Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.1562Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.1113Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1903Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1973Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.6756Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.7808Inherited
    53335,53335
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.005378Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.2324Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.2324Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.001826Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.004504Inherited
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.05863Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.02763Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.5425Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.7701Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.7701Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 1Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.2324Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.06836Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.04265Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.5857Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.005161Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.06836Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.3428Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.5255Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.01116Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.008768Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.308Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.04023Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.103Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.1062Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.3771Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.9806Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.08724Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00102Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.1133Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.234Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.01352Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.2324Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.06836Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.001779Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.1062Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.1062Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.1062Inherited
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.01107Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.4079Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.1113Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.05863Inherited
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0.1062Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0.5551Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1352Inherited
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0.001779Inherited
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.002148Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.01695Inherited
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.03229Inherited
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.03229Inherited
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.03229Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.1062Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2127Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.06836Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.07666Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02705Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.01897Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8361Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.008588Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.06687Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.06687Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00102Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.8808Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.001779Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 1Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.4079Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.6664Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2205Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.3763Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.4625Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    48403,47769,140860
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.0000000003283Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000000003043Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001589Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001589Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000001758Direct
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000004815Direct
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0000005083Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000005083Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.000001035Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000001118Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00000498Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000005028Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00005184Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.0000655Direct
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0001519Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0002087Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0007266Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1113Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.3771Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.308Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.2814Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.004208Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.7701Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2856Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.01897Inherited
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.005161Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.1787Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.1562Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.5255Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1113Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1903Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.5041Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001779Inherited
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.1062Inherited
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.03229Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.1062Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.1062Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.001049Inherited
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.03229Inherited
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.03229Inherited
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.03229Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.03595Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.1062Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.008768Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02705Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.006425Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.06687Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4079Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.3603Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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