SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): signaling

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ 1:   biological_process [GO:0008150] <24>
0:   signaling [GO:0023052] <2>(48|44) (351|369|223)
- 1:   single organism signaling [GO:0044700] <7>(48|44) (351|366|220)
- 1:   multi-organism signaling [GO:0035636](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
14-3-3 protein0.00000010370.00019Direct
4-helical cytokines00Direct
Bcl-2 inhibitors of programmed cell death00Direct
CheY-like0.00000017660Direct
Cystine-knot cytokines0.000002480Direct
Cytokine0.0000000000000046850Direct
E set domains0.000007570.000000000001201Direct
EF-hand0.0000000083390.00000000001242Direct
Family A G protein-coupled receptor-like00Direct
Histidine-containing phosphotransfer domain, HPT domain0.00000000093030.000000000003661Direct
Immunoglobulin00Direct
Interleukin 8-like chemokines00Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000031780Direct
PDZ domain-like0.00095220Direct
Protein kinase-like (PK-like)00Direct
Regulator of G-protein signaling, RGS0.0000000099460Direct
Transducin (heterotrimeric G protein), gamma chain0.000000000000014920.000000000000009084Direct
SNF-like0.11750.7744Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)11Inherited
Proton glutamate symport protein0.075950.3352Inherited
Caspase-like0.0190.007327Inherited
Gamma-glutamyl cyclotransferase-like0.12520.8212Inherited
HIT-like0.001630.8214Inherited
Ribonuclease H-like0.7221Inherited
NAD(P)-binding Rossmann-fold domains11Inherited
KRAB domain (Kruppel-associated box)0.33631Inherited
The spindle assembly checkpoint protein mad20.000045610.1308Inherited
Carbonic anhydrase0.00039830.3119Inherited
Cu,Zn superoxide dismutase-like0.0000019760.03271Inherited
P-loop containing nucleoside triphosphate hydrolases01Inherited
ALDH-like11Inherited
Class I glutamine amidotransferase-like0.62941Inherited
Defensin-like0.00000017350.002317Inherited
alpha/beta-Hydrolases11Inherited
Bet v1-like0.00079090.3032Inherited
Serpins0.016330.2429Inherited
Nucleoside diphosphate kinase, NDK0.0091980.2798Inherited
Ankyrin repeat0.73841Inherited
WD40 repeat-like0.023011Inherited
Annexin0.0000058820.04978Inherited
LanC-like0.00010710.00251Inherited
Cupredoxins0.0059060.8851Inherited
Insulin-like0.016650.00003119Inherited
Cysteine proteinases0.0023771Inherited
L domain-like0.0063840Inherited
C-type lectin-like0.026960.01317Inherited
RNI-like0.78370.9909Inherited
Metallothionein0.0063740.2484Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
14-3-3 protein0.00000043430.0007515Direct
Bcl-2 inhibitors of programmed cell death00Direct
CheY-related0.00000012340Direct
Defensin0.00000000000014850.00000266Direct
Ephrin ectodomain0.000000011430Direct
Fibroblast growth factors (FGF)0.0000000000000022720Direct
G proteins00Direct
Interferons/interleukin-10 (IL-10)0.000000000056480.0001083Direct
Interleukin 8-like chemokines00Direct
Long-chain cytokines0.00000000010890.0000000000001115Direct
Phosphorelay protein-like0.000000000017170.000000002997Direct
Protein kinases, catalytic subunit00Direct
Regulator of G-protein signaling, RGS0.000000033580Direct
Rhodopsin-like00Direct
Short-chain cytokines00.00000000000313Direct
Transducin (heterotrimeric G protein), gamma chain0.00000000000017090.000000000001335Direct
V set domains (antibody variable domain-like)00Direct
SNF-like0.17970.8895Inherited
Proteasome subunits0.89261Inherited
Proton glutamate symport protein0.10280.4368Inherited
Caspase catalytic domain0.028460.01357Inherited
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0.0032170.1809Inherited
Tyrosine-dependent oxidoreductases11Inherited
KRAB domain (Kruppel-associated box)0.40121Inherited
The spindle assembly checkpoint protein mad20.0001110.09991Inherited
Carbonic anhydrase0.0010110.4447Inherited
Cu,Zn superoxide dismutase-like0.0000084930.07093Inherited
ALDH-like11Inherited
DJ-1/PfpI0.081770.7465Inherited
Calmodulin-like0.00056770.09377Inherited
Carboxylesterase0.21671Inherited
Serpins0.046770.4565Inherited
B56-like0.006560.00003943Inherited
Gonadodropin/Follitropin0.00095480.1032Inherited
RhoGDI-like0.000017930.01793Inherited
Nucleoside diphosphate kinase, NDK0.018750.4135Inherited
Ankyrin repeat0.85711Inherited
WD40-repeat0.039111Inherited
Annexin0.000023950.1132Inherited
Insulin-like0.028460.0003003Inherited
C-type lectin domain0.04340.4123Inherited
C1 set domains (antibody constant domain-like)0.013660Inherited
Papain-like0.000011390.2905Inherited
Metallothionein0.017190.3928Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Plexin repeat0Direct
Immunoglobulin0Direct
Transducin (alpha subunit), insertion domain0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Hormone receptor domain0Direct
Cystine-knot cytokines0Direct
DPY module0Direct
Regulator of G-protein signaling, RGS0Direct
Cytokine0Direct
SH3-domain0Direct
Protein kinase-like (PK-like)0Direct
PH domain-like0Direct
Periplasmic binding protein-like I0Direct
Ras GEF0Direct
L domain-like0Direct
MHC antigen-recognition domain0Direct
Cysteine-rich domain0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Growth factor receptor domain0Direct
SAM/Pointed domain0Direct
GTPase activation domain, GAP0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Toll/Interleukin receptor TIR domain0Direct
Snake toxin-like0Direct
Family A G protein-coupled receptor-like0Direct
Ubiquitin-like0Direct
CheY-like0Direct
EGF/Laminin0Direct
Interleukin 8-like chemokines0Direct
DEATH domain0Direct
Transcription factor STAT-4 N-domain0Direct
4-helical cytokines0Direct
SMAD/FHA domain0Direct
STAT0Direct
Voltage-gated potassium channels0Direct
SH2 domain0Direct
Frizzled cysteine-rich domain0Direct
Homodimeric domain of signal transducing histidine kinase0Direct
Fibronectin type III0Direct
Bcl-2 inhibitors of programmed cell death0Direct
Sema domain0Direct
PDZ domain-like0Direct
Nicotinic receptor ligand binding domain-like0Direct
TNF-like0Direct
Crustacean CHH/MIH/GIH neurohormone0Direct
TNF receptor-like0Direct
SMAD MH1 domain0Direct
p53-like transcription factors0Direct
gp120 core0Direct
DBL homology domain (DH-domain)0.000000000000002832Direct
Leucine zipper domain0.000000000000003737Direct
Transducin (heterotrimeric G protein), gamma chain0.00000000000000466Direct
Methuselah ectodomain0.00000000000001092Direct
Hedgehog/DD-peptidase0.00000000000006658Direct
E set domains0.0000000000006559Direct
Plakin repeat0.0000000000007009Direct
Nucleotide cyclase0.0000000000007278Direct
Hedgehog/intein (Hint) domain0.000000000001362Direct
Notch domain0.00000000000149Direct
Histidine-containing phosphotransfer domain, HPT domain0.000000000002029Direct
EF-hand0.000000000007Direct
Heparin-binding domain from vascular endothelial growth factor0.00000000001406Direct
Spectrin repeat0.00000000002327Direct
Orange domain-like0.0000000000554Direct
Virus ectodomain0.00000000005865Direct
GAS2 domain-like0.0000000003266Direct
(Phosphotyrosine protein) phosphatases II0.000000001068Direct
Galactose-binding domain-like0.000000003009Direct
cAMP-binding domain-like0.000000005487Direct
HAMP domain-like0.00000001045Direct
Nuclear receptor ligand-binding domain0.00000002071Direct
NAD kinase/diacylglycerol kinase-like0.00000002548Direct
DNA-binding protein LAG-1 (CSL)0.00000003641Direct
GAF domain-like0.00000004424Direct
Spermadhesin, CUB domain0.00000009458Direct
Agouti-related protein0.0000001668Direct
p53 tetramerization domain0.0000003174Direct
Fibrinogen C-terminal domain-like0.0000005076Direct
G protein-binding domain0.0000005805Direct
C-terminal autoproteolytic domain of nucleoporin nup980.000002188Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0.000002252Direct
Satiety factor CART (cocaine and amphetamine regulated transcript)0.000003126Direct
Sporulation response regulatory protein Spo0B0.000003126Direct
PYP-like sensor domain (PAS domain)0.000003652Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.000004211Direct
Phenylalanine zipper0.000005283Direct
BAR/IMD domain-like0.000005433Direct
Concanavalin A-like lectins/glucanases0.000005721Direct
t-snare proteins0.00000585Direct
Glucocorticoid receptor-like (DNA-binding domain)0.000008094Direct
Sensory domain-like0.0000139Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.00001932Direct
Insulin-like0.00002095Direct
A heparin-binding domain0.00002175Direct
Integrin beta tail domain0.00002505Direct
Periplasmic binding protein-like II0.00002744Direct
N-terminal domain of cbl (N-cbl)0.00003101Direct
IP3 receptor type 1 binding core, domain 20.00003365Direct
Kix domain of CBP (creb binding protein)0.00005297Direct
Suppressor of Fused, N-terminal domain0.00005841Direct
Trimerization domain of TRAF0.00006001Direct
YWTD domain0.00006532Direct
TAZ domain0.00008162Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.00008386Direct
PP2C-like0.00008475Direct
Integrin domains0.00008516Direct
SOCS box-like0.00008629Direct
DNA-binding domain0.00008665Direct
L27 domain0.00008965Direct
HD-domain/PDEase-like0.00009806Direct
Chitinase insertion domain0.0001025Direct
14-3-3 protein0.0001313Direct
NRDP1 C-terminal domain-like0.0001339Direct
WW domain0.0001363Direct
Nuclear receptor coactivator interlocking domain0.0001824Direct
GDNF receptor-like0.0002716Direct
LDL receptor-like module0.0003452Direct
AMPKBI-like0.0003511Direct
Nucleoporin domain0.0003644Direct
Class II MHC-associated invariant chain ectoplasmic trimerization domain0.0004753Direct
Calponin-homology domain, CH-domain0.0006566Direct
Second domain of FERM0.0007416Direct
BAG domain0.0009277Direct
DNA-binding domain of EIN3-like0.000969Direct
BRK domain-like0.1434Inherited
SNF-like0.6791Inherited
N-terminal coiled coil domain from apc0.001114Inherited
Tumor suppressor gene product Apc0.001114Inherited
HMG-box0.7729Inherited
"Winged helix" DNA-binding domain1Inherited
ARM repeat0.3946Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
MIR domain0.02981Inherited
PAZ domain1Inherited
Subdomain of clathrin and coatomer appendage domain0.4658Inherited
Clathrin adaptor appendage domain0.9729Inherited
Arginase/deacetylase0.9233Inherited
HLH, helix-loop-helix DNA-binding domain0.006063Inherited
TIMP-like0.006994Inherited
C-terminal domain of PLC-beta0.1173Inherited
Tetraspanin0.6403Inherited
Metallo-dependent phosphatases1Inherited
Synuclein0.07469Inherited
Ypt/Rab-GAP domain of gyp1p0.9812Inherited
Tubby C-terminal domain-like0.1887Inherited
GFP-like0.09189Inherited
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.003112Inherited
Proton glutamate symport protein0.279Inherited
Cdc48 domain 2-like0.6796Inherited
ADC-like1Inherited
Cyclin-like0.8986Inherited
Cullin homology domain0.03093Inherited
DNA repair protein MutS, domain III0.7191Inherited
HIT-like0.7242Inherited
SPOC domain-like0.002513Inherited
ERO1-like0.002812Inherited
DHS-like NAD/FAD-binding domain1Inherited
E2F-DP heterodimerization region0.007158Inherited
Caspase-like0.005401Inherited
C-terminal domain of Ku800.01088Inherited
Gamma-glutamyl cyclotransferase-like0.724Inherited
DNase I-like0.09237Inherited
Calcium ATPase, transduction domain A1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
Calcium ATPase, transmembrane domain M1Inherited
Connexin430.005051Inherited
HAD-like1Inherited
RING/U-box1Inherited
UBA-like1Inherited
BRCT domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain1Inherited
Formin homology 2 domain (FH2 domain)0.6437Inherited
Supernatant protein factor (SPF), C-terminal domain0.8506Inherited
vWA-like0.8837Inherited
Putative DNA-binding domain1Inherited
SAND domain-like0.3574Inherited
Nucleotide-diphospho-sugar transferases1Inherited
N-acetylmuramoyl-L-alanine amidase-like0.769Inherited
UBC-like1Inherited
PAP/OAS1 substrate-binding domain1Inherited
Nucleotidyltransferase1Inherited
PLP-dependent transferases1Inherited
SRF-like0.9224Inherited
Band 7/SPFH domain1Inherited
Formate/glycerate dehydrogenase catalytic domain-like1Inherited
Mitochondrial glycoprotein MAM33-like0.006279Inherited
Kringle-like0.4522Inherited
Hairpin loop containing domain-like1Inherited
Alkaline phosphatase-like0.4404Inherited
Thyroglobulin type-1 domain0.4095Inherited
KRAB domain (Kruppel-associated box)1Inherited
ArfGap/RecO-like zinc finger0.2968Inherited
PriA/YqbF domain0.5329Inherited
GINS helical bundle-like0.5623Inherited
post-AAA+ oligomerization domain-like1Inherited
Ran binding protein zinc finger-like0.25Inherited
Rap/Ran-GAP0.001821Inherited
beta-sandwich domain of Sec23/241Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
Glycerol-3-phosphate (1)-acyltransferase1Inherited
HSP40/DnaJ peptide-binding domain0.7811Inherited
Cystatin/monellin1Inherited
Hect, E3 ligase catalytic domain0.5348Inherited
lambda repressor-like DNA-binding domains1Inherited
DnaJ/Hsp40 cysteine-rich domain0.6121Inherited
RNA-binding domain, RBD1Inherited
AhpD-like0.307Inherited
SWIB/MDM2 domain0.7013Inherited
Chromo domain-like1Inherited
The spindle assembly checkpoint protein mad20.1046Inherited
Cysteine proteinases1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Ribonuclease H-like1Inherited
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.03468Inherited
TSP-1 type 1 repeat0.8867Inherited
SAP domain0.8956Inherited
RNI-like0.894Inherited
Cu,Zn superoxide dismutase-like0.02507Inherited
Cysteine-rich DNA binding domain, (DM domain)0.3148Inherited
Carboxypeptidase regulatory domain-like0.09472Inherited
NHL repeat0.2286Inherited
VHP, Villin headpiece domain0.1063Inherited
Defensin-like0.001675Inherited
GLA-domain0.1929Inherited
C-terminal effector domain of the bipartite response regulators0.1025Inherited
MAST3 pre-PK domain-like0.005009Inherited
Ankyrin repeat1Inherited
SET domain1Inherited
Multidrug efflux transporter AcrB transmembrane domain0.5259Inherited
WD40 repeat-like1Inherited
FAD/NAD(P)-binding domain1Inherited
Mitochondrial carrier1Inherited
Hook domain0.3225Inherited
Cap-Gly domain0.3599Inherited
Chaperone J-domain1Inherited
PapD-like0.01865Inherited
Rhomboid-like0.1837Inherited
Seven-hairpin glycosidases0.2323Inherited
P-domain of calnexin/calreticulin0.5647Inherited
Sec63 N-terminal domain-like0.8756Inherited
Actin-like ATPase domain1Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain1Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain1Inherited
Subtilisin-like1Inherited
PA domain1Inherited
ALDH-like1Inherited
Lipoxigenase0.8879Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)1Inherited
Cryptochrome/photolyase, N-terminal domain0.8411Inherited
Cryptochrome/photolyase FAD-binding domain0.9092Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
PreATP-grasp domain1Inherited
ENTH/VHS domain0.01122Inherited
Eferin C-derminal domain-like0.1588Inherited
Cation efflux protein cytoplasmic domain-like0.6297Inherited
Cation efflux protein transmembrane domain-like0.979Inherited
Class I glutamine amidotransferase-like1Inherited
Dimerization cofactor of HNF-1 alpha0.07983Inherited
SNARE fusion complex0.004755Inherited
FYVE/PHD zinc finger0.4683Inherited
POZ domain1Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.9008Inherited
FAT domain of focal adhesion kinase0.005821Inherited
CCCH zinc finger0.7798Inherited
Metallothionein0.2037Inherited
Homeodomain-like1Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain1Inherited
Nudix1Inherited
Heme-dependent peroxidases0.4254Inherited
Cullin repeat-like0.01806Inherited
Sec1/munc18-like (SM) proteins0.7585Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.8663Inherited
Thioredoxin-like1Inherited
GST C-terminal domain-like1Inherited
Intermediate filament protein, coiled coil region1Inherited
Moesin tail domain0.2492Inherited
alpha/beta-Hydrolases1Inherited
Histone-fold1Inherited
WRKY DNA-binding domain0.2358Inherited
F-box domain1Inherited
TPR-like1Inherited
Cytochrome P4501Inherited
HCP-like1Inherited
B-box zinc-binding domain0.4573Inherited
Pectin lyase-like1Inherited
Trypsin-like serine proteases1Inherited
Serpins0.1991Inherited
Phospholipase D/nuclease0.04017Inherited
SAICAR synthase-like0.0166Inherited
CalX-like0.005689Inherited
PX domain0.132Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.6832Inherited
ValRS/IleRS/LeuRS editing domain0.9306Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases1Inherited
PIN domain-like1Inherited
Phoshotransferase/anion transport protein1Inherited
ARID-like0.7124Inherited
Cadherin-like0.2932Inherited
Small-conductance potassium channel0.02914Inherited
Bet v1-like0.2512Inherited
Actin depolymerizing proteins0.8068Inherited
Polo-box domain0.003992Inherited
A DNA-binding domain in eukaryotic transcription factors0.00876Inherited
CRAL/TRIO domain0.01465Inherited
RGC domain-like0.002313Inherited
Composite domain of metallo-dependent hydrolases1Inherited
RUN domain-like0.7397Inherited
Ligand-binding domain in the NO signalling and Golgi transport0.0552Inherited
Nitric oxide (NO) synthase oxygenase domain0.004074Inherited
Flavoproteins1Inherited
Riboflavin synthase domain-like0.2885Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.3371Inherited
(Trans)glycosidases1Inherited
Nucleoside diphosphate kinase, NDK0.2308Inherited
beta-beta-alpha zinc fingers1Inherited
Ricin B-like lectins1Inherited
Bromodomain1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited
Mib/herc2 domain-like0.0966Inherited
WWE domain0.6515Inherited
Zn-binding ribosomal proteins0.9463Inherited
PKD domain0.3789Inherited
BPTI-like0.009998Inherited
Tropomyosin1Inherited
Eukaryotic type KH-domain (KH-domain type I)1Inherited
Complement control module/SCR domain1Inherited
Carbonic anhydrase0.2587Inherited
Oligoxyloglucan reducing end-specific cellobiohydrolase0.4037Inherited
Annexin0.03858Inherited
LanC-like0.001818Inherited
EPT/RTPC-like0.4326Inherited
DUSP-like0.2831Inherited
GYF domain0.4963Inherited
C-terminal, gelsolin-like domain of Sec23/241Inherited
Cupredoxins0.7869Inherited
Kelch motif0.2918Inherited
TB module/8-cys domain0.00182Inherited
Blood coagulation inhibitor (disintegrin)0.002443Inherited
Quinoprotein alcohol dehydrogenase-like0.1163Inherited
C-type lectin-like0.009849Inherited
PLC-like phosphodiesterases0.0221Inherited
Integrin alpha N-terminal domain0.006484Inherited
SEA domain0.008972Inherited
Serine protease inhibitors0.9502Inherited
Phase 1 flagellin0.06039Inherited
TRAF domain-like0.01305Inherited
Fibrinogen coiled-coil and central regions0.09189Inherited
Triple coiled coil domain of C-type lectins0.2493Inherited
FnI-like domain0.5693Inherited
EAL domain-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    50998,56112
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54001,55205
  • 54001 - Cysteine proteinases
  • 55205 - EPT/RTPC-like
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0Direct
    57362,49899
  • 57362 - BPTI-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0Direct
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    54928,111331
  • 54928 - RNA-binding domain, RBD
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    55785,55890
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55890 - Sporulation response regulatory protein Spo0B
  • 0Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    63712,63712
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 0Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    103190,55785
  • 103190 - Sensory domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    55785,47384
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    55890,55874
  • 55890 - Sporulation response regulatory protein Spo0B
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    54236,54928
  • 54236 - Ubiquitin-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    57184,90148
  • 57184 - Growth factor receptor domain
  • 90148 - DPY module
  • 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    143791,54236
  • 143791 - DUSP-like
  • 54236 - Ubiquitin-like
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    81606,55073
  • 81606 - PP2C-like
  • 55073 - Nucleotide cyclase
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    55874,52172
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 0Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50729,57997
  • 50729 - PH domain-like
  • 57997 - Tropomyosin
  • 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0Direct
    57889,111331
  • 57889 - Cysteine-rich domain
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    81995,54236
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 0Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 9.676e-16Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000000000000002832Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.000000000000003737Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000000000005554Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0.00000000000001004Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.00000000000001622Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00000000000003698Direct
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000000000006235Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.0000000000002572Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0000000000003614Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0000000000004651Direct
    52540,47473
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47473 - EF-hand
  • 0.0000000000004651Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0.0000000000006165Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0.0000000000006482Direct
    81383,49899
  • 81383 - F-box domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000000007056Direct
    53850,81324
  • 53850 - Periplasmic binding protein-like II
  • 81324 - Voltage-gated potassium channels
  • 0.000000000001119Direct
    56502,56502
  • 56502 - gp120 core
  • 56502 - gp120 core
  • 0.000000000001226Direct
    47473,52540
  • 47473 - EF-hand
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000001446Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.000000000001912Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.000000000002127Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0.000000000002365Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.000000000003275Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.000000000004934Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.000000000006615Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000006777Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.000000000008042Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.00000000001016Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.00000000001657Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00000000002611Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.00000000003573Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.000000000107Direct
    52172,46689
  • 52172 - CheY-like
  • 46689 - Homeodomain-like
  • 0.000000000107Direct
    158472,47384
  • 158472 - HAMP domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0.0000000001332Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.0000000002196Direct
    52172,47226
  • 52172 - CheY-like
  • 47226 - Histidine-containing phosphotransfer domain, HPT domain
  • 0.000000000495Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0000000008865Direct
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.000000002619Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.0000000028Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.000000002876Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.000000003437Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.000000004474Direct
    52058,81321
  • 52058 - L domain-like
  • 81321 - Family A G protein-coupled receptor-like
  • 0.00000001328Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.00000001387Direct
    52058,52200
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0000000289Direct
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.00000003641Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.0000000367Direct
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.00000004052Direct
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.0000000552Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.00000007993Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0000001005Direct
    52172,52172
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0.0000002077Direct
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.0000002077Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0000002574Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000002688Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.0000003174Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0000003279Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.0000003852Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000004756Direct
    48670,48097
  • 48670 - Transducin (heterotrimeric G protein), gamma chain
  • 48097 - Regulator of G-protein signaling, RGS
  • 0.0000005469Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0000009406Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.000000973Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000001129Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0.000001155Direct
    50729,46785
  • 50729 - PH domain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00000122Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.00000122Direct
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.000001866Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.000002082Direct
    54236,54001
  • 54236 - Ubiquitin-like
  • 54001 - Cysteine proteinases
  • 0.000003044Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.000003465Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.000003781Direct
    50729,48366
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.000003798Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0.000003798Direct
    57184,49854
  • 57184 - Growth factor receptor domain
  • 49854 - Spermadhesin, CUB domain
  • 0.000003798Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.000004211Direct
    52172,52540
  • 52172 - CheY-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000004684Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000005622Direct
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.00000939Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.000009574Direct
    50044,56112
  • 50044 - SH3-domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000977Direct
    48366,47473
  • 48366 - Ras GEF
  • 47473 - EF-hand
  • 0.00001013Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.00001116Direct
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.00001132Direct
    100909,48371
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 48371 - ARM repeat
  • 0.00001146Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.00001212Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00001376Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.00001519Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0.00001628Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.00001729Direct
    46785,50156
  • 46785 - "Winged helix" DNA-binding domain
  • 50156 - PDZ domain-like
  • 0.00001784Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.00001876Direct
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001932Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.00002011Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.00002194Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.00002194Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 0.00002253Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.00002505Direct
    50044,140741
  • 50044 - SH3-domain
  • 140741 - RUN domain-like
  • 0.00002727Direct
    50729,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 0.00003022Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.00003308Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00003574Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00003962Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.00004448Direct
    57953,49599
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0.00006001Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.00006001Direct
    48350,50729
  • 48350 - GTPase activation domain, GAP
  • 50729 - PH domain-like
  • 0.00006001Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.00006022Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.0001022Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.0001025Direct
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.0001166Direct
    63877,81321
  • 63877 - Methuselah ectodomain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.0001339Direct
    49599,160088
  • 49599 - TRAF domain-like
  • 160088 - NRDP1 C-terminal domain-like
  • 0.0001339Direct
    50729,47031
  • 50729 - PH domain-like
  • 47031 - Second domain of FERM
  • 0.0001339Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001513Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.0001527Direct
    47986,56112
  • 47986 - DEATH domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001538Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.0001824Direct
    55550,48366
  • 55550 - SH2 domain
  • 48366 - Ras GEF
  • 0.0002353Direct
    50985,48065
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 0.0002353Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0002355Direct
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.0002416Direct
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0002637Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.0002839Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0003497Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.0003829Direct
    49599,57953
  • 49599 - TRAF domain-like
  • 57953 - Trimerization domain of TRAF
  • 0.000396Direct
    52087,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 0.0004753Direct
    81321,81321
  • 81321 - Family A G protein-coupled receptor-like
  • 81321 - Family A G protein-coupled receptor-like
  • 0.0006356Direct
    48452,57850
  • 48452 - TPR-like
  • 57850 - RING/U-box
  • 0.000823Direct
    55785,55781
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55781 - GAF domain-like
  • 0.000854Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0.0008627Direct
    52172,109604
  • 52172 - CheY-like
  • 109604 - HD-domain/PDEase-like
  • 0.0009082Direct
    55781,55785
  • 55781 - GAF domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0009435Direct
    54373,51905
  • 54373 - FAD-linked reductases, C-terminal domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.000969Direct
    49854,49899
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000969Direct
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.000969Direct
    54277,56112
  • 54277 - CAD & PB1 domains
  • 56112 - Protein kinase-like (PK-like)
  • 0.000969Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7845Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.9365Inherited
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0.02753Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.005808Inherited
    48726,56112
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0.004361Inherited
    47769,56399
  • 47769 - SAM/Pointed domain
  • 56399 - ADP-ribosylation
  • 0.005009Inherited
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004151Inherited
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.02914Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.001027Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.006781Inherited
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0.4326Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.6518Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.001828Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.6275Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.07916Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.1371Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4326Inherited
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.003112Inherited
    103473,141571
  • 103473 - MFS general substrate transporter
  • 141571 - Pentapeptide repeat-like
  • 0.005081Inherited
    49313,49899
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02679Inherited
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.001236Inherited
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.001725Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.001854Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.5778Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00227Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.06861Inherited
    63825,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 0.005019Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.7965Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.00562Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01565Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7013Inherited
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.07507Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.148Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.007158Inherited
    49879,52113
  • 49879 - SMAD/FHA domain
  • 52113 - BRCT domain
  • 0.011Inherited
    46565,52833
  • 46565 - Chaperone J-domain
  • 52833 - Thioredoxin-like
  • 0.01516Inherited
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0.2638Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.008574Inherited
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0.005889Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 1Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.9715Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 1Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.9191Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.6571Inherited
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0.8094Inherited
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.3115Inherited
    54171,54171
  • 54171 - DNA-binding domain
  • 54171 - DNA-binding domain
  • 0.05113Inherited
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 1Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.7841Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.06078Inherited
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0.8347Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.1917Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.1968Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.7201Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.02787Inherited
    109640,57667
  • 109640 - KRAB domain (Kruppel-associated box)
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.9502Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 1Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    55781,47384
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0.001114Inherited
    47113,48065
  • 47113 - Histone-fold
  • 48065 - DBL homology domain (DH-domain)
  • 0.002477Inherited
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.02679Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.5834Inherited
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0.0966Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.9953Inherited
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.3659Inherited
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.4658Inherited
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.8371Inherited
    56112,48452
  • 56112 - Protein kinase-like (PK-like)
  • 48452 - TPR-like
  • 0.01516Inherited
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.04411Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.03157Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.09282Inherited
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.07494Inherited
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.1881Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02205Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.9829Inherited
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0.003112Inherited
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03417Inherited
    52540,46689
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46689 - Homeodomain-like
  • 0.001085Inherited
    52172,46894
  • 52172 - CheY-like
  • 46894 - C-terminal effector domain of the bipartite response regulators
  • 0.002307Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.006205Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 1Inherited
    46565,158702
  • 46565 - Chaperone J-domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.02596Inherited
    48452,46565
  • 48452 - TPR-like
  • 46565 - Chaperone J-domain
  • 0.3435Inherited
    49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
  • 0.5647Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 1Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 1Inherited
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.6754Inherited
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.8347Inherited
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0.8278Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 1Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.9485Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.001296Inherited
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0.3792Inherited
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.02914Inherited
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.08531Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.03542Inherited
    57863,50729
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 0.001934Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 1Inherited
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.003112Inherited
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.003112Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.8048Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.2185Inherited
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.005081Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.06573Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.02695Inherited
    57581,57581
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 0.09399Inherited
    56112,47473
  • 56112 - Protein kinase-like (PK-like)
  • 47473 - EF-hand
  • 0.06885Inherited
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.05502Inherited
    81383,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 0.6656Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.02271Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    48371,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06866Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.001579Inherited
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.9306Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2298Inherited
    81324,81327
  • 81324 - Voltage-gated potassium channels
  • 81327 - Small-conductance potassium channel
  • 0.02914Inherited
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.02013Inherited
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.004132Inherited
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.04887Inherited
    52087,48350
  • 52087 - CRAL/TRIO domain
  • 48350 - GTPase activation domain, GAP
  • 0.001774Inherited
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0.004151Inherited
    52540,158235
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 158235 - SOCS box-like
  • 0.001744Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.00315Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.992Inherited
    64268,50729
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 0.003238Inherited
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0.001115Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.677Inherited
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.01245Inherited
    53448,50370
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 50370 - Ricin B-like lectins
  • 0.6914Inherited
    48403,158235
  • 48403 - Ankyrin repeat
  • 158235 - SOCS box-like
  • 0.222Inherited
    54236,57829
  • 54236 - Ubiquitin-like
  • 57829 - Zn-binding ribosomal proteins
  • 0.03926Inherited
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.1046Inherited
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0.5593Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.01936Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.9245Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    57535,53822
  • 57535 - Complement control module/SCR domain
  • 53822 - Periplasmic binding protein-like I
  • 0.002477Inherited
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.001114Inherited
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0.008774Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.005959Inherited
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.01327Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.4308Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.6716Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.01064Inherited
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.1652Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.677Inherited
    48350,55550
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0.05184Inherited
    50044,48350
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 0.0846Inherited
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.004151Inherited
    48726,57424
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 0.001584Inherited
    57424,48726
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 0.01022Inherited
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.04646Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.001031Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.001031Inherited
    50729,90209
  • 50729 - PH domain-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.002477Inherited
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.1151Inherited
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.2088Inherited
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.01827Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.02727Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.03851Inherited
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.005081Inherited
    159034,57850
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 0.01399Inherited
    57850,159034
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0.01399Inherited
    117839,117839
  • 117839 - WWE domain
  • 117839 - WWE domain
  • 0.01529Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.02787Inherited
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.06804Inherited
    68906,57850
  • 68906 - SAP domain
  • 57850 - RING/U-box
  • 0.001373Inherited
    51445,51445
  • 51445 - (Trans)glycosidases
  • 51445 - (Trans)glycosidases
  • 0.001774Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.003184Inherited
    57567,57567
  • 57567 - Serine protease inhibitors
  • 57567 - Serine protease inhibitors
  • 0.03468Inherited
    57567,57603
  • 57567 - Serine protease inhibitors
  • 57603 - FnI-like domain
  • 0.0798Inherited
    47986,52200
  • 47986 - DEATH domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.011Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.04179Inherited
    52047,52200
  • 52047 - RNI-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.011Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.07663Inherited
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.2493Inherited
    55785,55073
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55073 - Nucleotide cyclase
  • 0.03468Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    81995,54236,50729
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0Direct
    57889,57889,111331
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54236,54928,111331
  • 54236 - Ubiquitin-like
  • 54928 - RNA-binding domain, RBD
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    54236,54236,54928
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57362,49899,49899
  • 57362 - BPTI-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    103190,55785,55890
  • 103190 - Sensory domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55890 - Sporulation response regulatory protein Spo0B
  • 0Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    55785,47384,55874
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    55785,55890,55874
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55890 - Sporulation response regulatory protein Spo0B
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    63712,63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    101912,103575,81296
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    47384,55874,52172
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 0Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 9.676e-16Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 9.676e-16Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000000000000001898Direct
    50729,57889,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00000000000001446Direct
    57889,57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0000000000001022Direct
    52540,47473,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47473 - EF-hand
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000000000001341Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000000000006165Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0000000000008525Direct
    53822,53850,81324
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 81324 - Voltage-gated potassium channels
  • 0.000000000001119Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.000000000009763Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.00000000001288Direct
    158472,47384,55874
  • 158472 - HAMP domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.00000000005432Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.0000000000665Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.000000000107Direct
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.0000000001668Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0000000001694Direct
    47031,50729,55550
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.0000000003331Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000000003331Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000634Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000001011Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000002388Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.000000002874Direct
    55550,50044,55550
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000000004443Direct
    50044,55550,50729
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.000000004474Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000000598Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00000001077Direct
    50044,55550,50044
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00000001328Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.00000001469Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00000001769Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.0000000367Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0000000367Direct
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.00000004052Direct
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.00000004631Direct
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.00000004685Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000002004Direct
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.0000004165Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000004366Direct
    55550,50044,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0000005643Direct
    55874,52172,47226
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 47226 - Histidine-containing phosphotransfer domain, HPT domain
  • 0.000000565Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.0000005892Direct
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.0000006149Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0000007879Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.000001155Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.00000122Direct
    52172,52540,46689
  • 52172 - CheY-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46689 - Homeodomain-like
  • 0.000002147Direct
    55874,52172,52172
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0.000003316Direct
    50729,50156,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.000003781Direct
    48065,50729,48366
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.000003798Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.000009574Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.000009983Direct
    48366,47473,57889
  • 48366 - Ras GEF
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0.00001013Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00001205Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001574Direct
    52058,52058,52200
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.00001628Direct
    48065,50729,46785
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00001784Direct
    46785,50156,50156
  • 46785 - "Winged helix" DNA-binding domain
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00001784Direct
    46785,46785,50156
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 50156 - PDZ domain-like
  • 0.00001784Direct
    50729,46785,46785
  • 50729 - PH domain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00001784Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.00002194Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.00002194Direct
    57184,57184,63825
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.00002727Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00002727Direct
    63825,57184,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00002727Direct
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00003717Direct
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00003717Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00005633Direct
    47986,47986,52540
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00006001Direct
    55781,55785,47384
  • 55781 - GAF domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0.00007614Direct
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001339Direct
    57850,49599,160088
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 160088 - NRDP1 C-terminal domain-like
  • 0.0001339Direct
    47031,50729,47031
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 47031 - Second domain of FERM
  • 0.0001339Direct
    50729,47031,50729
  • 50729 - PH domain-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0001339Direct
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.0001538Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0001855Direct
    50729,49562,48350
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.0002294Direct
    48065,50729,82185
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.0002353Direct
    50985,48065,50729
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0002353Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0002355Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0002355Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0003023Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.0003829Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0003829Direct
    55781,47384,55874
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.000394Direct
    49599,57953,49599
  • 49599 - TRAF domain-like
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0.000396Direct
    52087,46966,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0004753Direct
    55785,55781,55781
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0004753Direct
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.0004754Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0006238Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0006325Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0006356Direct
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0006356Direct
    48065,50729,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0006617Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0008584Direct
    48726,48726,56112
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0.0009435Direct
    51905,54373,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.000969Direct
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.000969Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000969Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7531Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7845Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01196Inherited
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.004361Inherited
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.1748Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3992Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.416Inherited
    103473,103473,141571
  • 103473 - MFS general substrate transporter
  • 103473 - MFS general substrate transporter
  • 141571 - Pentapeptide repeat-like
  • 0.005081Inherited
    49313,49313,49899
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02054Inherited
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.001236Inherited
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.001725Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.001854Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.003357Inherited
    51905,51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.04887Inherited
    46565,52833,52833
  • 46565 - Chaperone J-domain
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.002477Inherited
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0.005889Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.7364Inherited
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.3444Inherited
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.04115Inherited
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.8347Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.2316Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.02323Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02323Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.02787Inherited
    109640,57667,57667
  • 109640 - KRAB domain (Kruppel-associated box)
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.6735Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.02679Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1021Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1985Inherited
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.3328Inherited
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.4492Inherited
    57196,57196,63825
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.04322Inherited
    57424,57196,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05773Inherited
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.0674Inherited
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.1691Inherited
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03417Inherited
    55785,55785,47384
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0.01516Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1809Inherited
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.2493Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 1Inherited
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 1Inherited
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.6754Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.06039Inherited
    57863,50729,50729
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.001934Inherited
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 1Inherited
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.003112Inherited
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.003112Inherited
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.003112Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1336Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.007505Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.004437Inherited
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.04764Inherited
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.04764Inherited
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.0674Inherited
    57581,57581,57184
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.09189Inherited
    57581,57196,57184
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1045Inherited
    57581,57184,57196
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1325Inherited
    57184,57581,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 0.1964Inherited
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.2313Inherited
    81383,52047,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.02075Inherited
    54928,54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    48371,52540,52540
  • 48371 - ARM repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06866Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2678Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.01245Inherited
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.4242Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.8798Inherited
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.01245Inherited
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.08531Inherited
    54236,54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.4013Inherited
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01138Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.01401Inherited
    57535,57535,53822
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 53822 - Periplasmic binding protein-like I
  • 0.002477Inherited
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.005009Inherited
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.008422Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.007517Inherited
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.4003Inherited
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.1393Inherited
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.6515Inherited
    50044,48350,55550
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0.05184Inherited
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.004151Inherited
    48726,57424,57424
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.001584Inherited
    57424,57424,48726
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 0.0086Inherited
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.001545Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.00262Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.724Inherited
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.01827Inherited
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.06804Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.027Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.02727Inherited
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.003129Inherited
    159034,57850,159034
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0.01399Inherited
    48452,81901,48452
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 0.03926Inherited
    81901,48452,48452
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.05113Inherited
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.001003Inherited
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.001559Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.003184Inherited
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00763Inherited
    52058,52047,52200
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.007605Inherited


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