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Biological Process (BP): neuron differentiation

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ + + + + + 6:   single-multicellular organism process [GO:0044707] <74>(83|99) (548|635|419)
+ + + + + 5:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
+ + + + + 5:   biological_process [GO:0008150] <24>
+ + + + + 5:   multicellular organism development [GO:0007275] <28>(76|90) (505|574|376)
+ + + + 4:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ + + + 4:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
+ + + + 4:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ + + + 4:   system development [GO:0048731] <30>(67|82) (479|532|350)
+ + + 3:   nervous system development [GO:0007399] <15>(24|26) (288|318|205)
+ + + 3:   single-organism cellular process [GO:0044763] <194>(233|302) (895|984|562)
+ + + 3:   single-organism developmental process [GO:0044767] <413>(85|101) (556|628|408)
+ + 2:   cellular developmental process [GO:0048869] <17>(54|55) (410|441|290)
+ + 2:   neurogenesis [GO:0022008] <2>(17|17) (253|274|179)
+ 1:   cell differentiation [GO:0030154] <91>(51|53) (394|430|283)
+ 1:   generation of neurons [GO:0048699] <7>(16|16) (245|262|173)
0:   neuron differentiation [GO:0030182] <19>(7|8) (205|196|142)
- 1:   central nervous system neuron differentiation [GO:0021953] <19>(2|2) (56|44|38)
- 1:   neuron development [GO:0048666] <12>(5|5) (176|178|129)
- 1:   neuron fate commitment [GO:0048663] <12>(1|1) (26|13|9)
- 1:   GABAergic neuron differentiation [GO:0097154] <4>(0|0) (3|1|0)
- 1:   hair cell differentiation [GO:0035315] <4>(1|1) (33|19|11)
- 1:   photoreceptor cell differentiation [GO:0046530] <4>(1|0) (53|25|20)
- 1:   mechanoreceptor differentiation [GO:0042490] <3>(1|1) (29|22|11)
- 1:   noradrenergic neuron differentiation [GO:0003357] <3>(0|0) (3|1|0)
- 1:   cardiac neuron differentiation [GO:0060945] <2>(0|0) (0|0|0)
- 1:   peripheral nervous system neuron differentiation [GO:0048934] <2>(0|0) (8|7|9)
- 1:   retinal bipolar neuron differentiation [GO:0060040] <2>(0|0) (1|0|0)
- 1:   dopaminergic neuron differentiation [GO:0071542] <1>(0|0) (8|2|0)
- 1:   neuron differentiation involved in amphid sensory organ development [GO:0003387] <1>(0|0) (0|0|0)
- 1:   positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiat [GO:1904081] <1>(0|0) (1|0|0)
- 1:   Rohon-Beard neuron differentiation [GO:1905275](0|0) (0|0|0)
- 1:   amacrine cell differentiation [GO:0035881](0|0) (3|0|0)
- 1:   glutamatergic neuron differentiation [GO:1905962](0|0) (2|1|0)
- 1:   medial motor column neuron differentiation [GO:0021526](0|0) (0|0|0)
- 1:   neuron differentiation involved in salivary gland development [GO:0060705](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cu,Zn superoxide dismutase-like0.0000018550.0007878Direct
Formate/glycerate dehydrogenase catalytic domain-like0.000000023850.0004325Direct
Immunoglobulin0.000006970Direct
Lipocalins0.0000040920.0009654Direct
HLH, helix-loop-helix DNA-binding domain0.0000022580.6395Inherited
Spectrin repeat0.00045640.6692Inherited
Trypsin-like serine proteases0.068691Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
CAF1-like ribonuclease0.00034990.0001278Direct
Cu,Zn superoxide dismutase-like0.0000012210.0006981Direct
Formate/glycerate dehydrogenases, substrate-binding domain0.000000029410.00008688Direct
Phoshatidylinositol transfer protein, PITP0.000000012610.0004278Direct
Retinol binding protein-like0.00000000031440.000002365Direct
HLH, helix-loop-helix DNA-binding domain0.0000014530.6157Inherited
Spectrin repeat0.00034990.8303Inherited
Eukaryotic proteases0.056411Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Immunoglobulin0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
EGF/Laminin0Direct
Concanavalin A-like lectins/glucanases0Direct
Fibronectin type III0Direct
A heparin-binding domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
Growth factor receptor domain0.000000000000003737Direct
Sema domain0.00000000000006066Direct
Galactose-binding domain-like0.000000000001145Direct
(Phosphotyrosine protein) phosphatases II0.0000000000819Direct
SAM/Pointed domain0.0000000001262Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.0000000004789Direct
L domain-like0.0000000005706Direct
Plexin repeat0.000000002512Direct
Ankyrin repeat0.000000002694Direct
HR1 repeat0.000000004776Direct
GAS2 domain-like0.00000002142Direct
PDZ domain-like0.00000002504Direct
Homeodomain-like0.00000003378Direct
TSP-1 type 1 repeat0.0000001392Direct
SH3-domain0.0000001523Direct
CCHHC domain0.0000001934Direct
RCC1/BLIP-II0.0000007632Direct
N-terminal coiled coil domain from apc0.00000123Direct
Tumor suppressor gene product Apc0.00000123Direct
Putative DNA-binding domain0.000001348Direct
Granulin repeat0.000001477Direct
Fibrinogen C-terminal domain-like0.000003113Direct
LDL receptor-like module0.000005652Direct
Plakin repeat0.000006189Direct
beta-sandwich domain of Sec23/240.000008062Direct
Doublecortin (DC)0.00001411Direct
GDNF receptor-like0.00008877Direct
Glucocorticoid receptor-like (DNA-binding domain)0.000106Direct
Spermadhesin, CUB domain0.0001108Direct
BPTI-like0.000144Direct
PH domain-like0.0001953Direct
Frizzled cysteine-rich domain0.0001999Direct
Carboxypeptidase regulatory domain-like0.0002383Direct
Formate/glycerate dehydrogenase catalytic domain-like0.0003032Direct
LigT-like0.0003489Direct
LEA14-like0.0003489Direct
PAH2 domain0.0003708Direct
Aspartate/ornithine carbamoyltransferase0.0003832Direct
Ran binding protein zinc finger-like0.000397Direct
Cu,Zn superoxide dismutase-like0.0005578Direct
Lipocalins0.0006867Direct
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.0008223Direct
DUSP-like0.000936Direct
UBC-like0.5542Inherited
Ribosomal protein S5 domain 2-like0.9624Inherited
B-box zinc-binding domain0.2379Inherited
lambda repressor-like DNA-binding domains0.3082Inherited
NHL repeat0.03774Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Family A G protein-coupled receptor-like1Inherited
Multidrug efflux transporter AcrB transmembrane domain0.7467Inherited
Synuclein0.01222Inherited
PYP-like sensor domain (PAS domain)0.3534Inherited
SAP domain0.7059Inherited
ARID-like0.9224Inherited
HMG-box1Inherited
Nuclear receptor ligand-binding domain0.8834Inherited
DNase I-like0.8936Inherited
Cap-Gly domain0.4446Inherited
vWA-like0.1837Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2847Inherited
Nicotinic receptor ligand binding domain-like0.3188Inherited
Notch domain0.008319Inherited
HLH, helix-loop-helix DNA-binding domain0.5524Inherited
Arginase/deacetylase0.2542Inherited
P-loop containing nucleoside triphosphate hydrolases0.7615Inherited
p53-like transcription factors1Inherited
SOCS box-like0.7562Inherited
Transcription factor STAT-4 N-domain0.649Inherited
STAT0.8045Inherited
Kringle-like0.00813Inherited
SH2 domain0.7673Inherited
Orange domain-like0.7487Inherited
Snake toxin-like1Inherited
SRF-like1Inherited
VHP, Villin headpiece domain0.01013Inherited
Sialidases0.004737Inherited
SMAD MH1 domain0.1637Inherited
Nitric oxide (NO) synthase oxygenase domain0.01033Inherited
SMAD/FHA domain0.9773Inherited
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0.005171Inherited
TAFH domain-like0.09713Inherited
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.08402Inherited
VPS9 domain0.001454Inherited
Carbamoyl phosphate synthetase, large subunit connection domain0.002328Inherited
TIMP-like0.00134Inherited
Hedgehog/DD-peptidase0.104Inherited
Hedgehog/intein (Hint) domain0.1318Inherited
Methylglyoxal synthase-like0.01033Inherited
BRK domain-like0.01013Inherited
Elafin-like0.027Inherited
FF domain0.006898Inherited
E set domains0.001469Inherited
SEA domain0.1795Inherited
Voltage-gated potassium channels0.007034Inherited
FAS1 domain0.2796Inherited
Formin homology 2 domain (FH2 domain)0.3645Inherited
Flavoproteins0.7651Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
Riboflavin synthase domain-like1Inherited
beta-beta-alpha zinc fingers1Inherited
DEATH domain0.1291Inherited
PRC-barrel domain0.002328Inherited
DBL homology domain (DH-domain)0.003448Inherited
PGBD-like0.04366Inherited
Hemopexin-like domain0.06006Inherited
Composite domain of metallo-dependent hydrolases0.009279Inherited
Cysteine-rich DNA binding domain, (DM domain)0.4369Inherited
UBA-like0.5422Inherited
Cytokine0.6848Inherited
Eferin C-derminal domain-like0.4446Inherited
Cdc48 domain 2-like0.3394Inherited
ADC-like0.3394Inherited
Calponin-homology domain, CH-domain0.8247Inherited
FYVE/PHD zinc finger0.03192Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.3175Inherited
Spectrin repeat0.58Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.365Inherited
FAD-linked reductases, C-terminal domain0.9958Inherited
Calcium ATPase, transduction domain A0.08805Inherited
Calcium ATPase, transmembrane domain M0.1255Inherited
Tudor/PWWP/MBT1Inherited
SNARE-like0.6718Inherited
CAD & PB1 domains0.3422Inherited
HCP-like0.7958Inherited
cAMP-binding domain-like0.218Inherited
Bet v1-like0.8826Inherited
alpha/beta-Hydrolases1Inherited
Complement control module/SCR domain0.3064Inherited
Cadherin-like0.05804Inherited
Second domain of FERM0.03902Inherited
Zn-finger domain of Sec23/240.005897Inherited
BAR/IMD domain-like0.09301Inherited
KA1-like0.09253Inherited
G protein-binding domain0.02549Inherited
Helical domain of Sec23/240.02549Inherited
YWTD domain0.1945Inherited
Stathmin0.7356Inherited
Apolipoprotein A-I0.04705Inherited
Intermediate filament protein, coiled coil region1Inherited
Ras GEF0.03268Inherited
Thyroglobulin type-1 domain0.06025Inherited
Kazal-type serine protease inhibitors0.1604Inherited
Cysteine proteinases0.9824Inherited
Ubiquitin-like0.04637Inherited
Hairpin loop containing domain-like0.05441Inherited
Periplasmic binding protein-like I0.6911Inherited
Periplasmic binding protein-like II1Inherited
Trypsin-like serine proteases1Inherited
TNF-like1Inherited
HAD-like1Inherited
WD40 repeat-like0.3318Inherited
ARM repeat0.8161Inherited
Cytochrome c oxidase subunit E0.01852Inherited
FnI-like domain1Inherited
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0.005946Inherited
ACT-like0.8588Inherited
Hook domain0.04518Inherited
SAND domain-like0.1271Inherited
alpha-catenin/vinculin-like0.2615Inherited
BEACH domain0.09713Inherited
Eukaryotic type KH-domain (KH-domain type I)0.6252Inherited
Caspase-like1Inherited
Chromo domain-like1Inherited
Activating enzymes of the ubiquitin-like proteins0.05943Inherited
WW domain0.5411Inherited
Tropomyosin1Inherited
C-type lectin-like0.001611Inherited
Calpain large subunit, middle domain (domain III)1Inherited
Metalloproteases ("zincins"), catalytic domain0.4001Inherited
GTPase activation domain, GAP0.01499Inherited
Cystine-knot cytokines1Inherited
Kelch motif0.08857Inherited
EF-hand1Inherited
Nucleotide cyclase0.5866Inherited
BRCT domain0.9679Inherited
Integrin alpha N-terminal domain1Inherited
"Winged helix" DNA-binding domain1Inherited
Heparin-binding domain from vascular endothelial growth factor1Inherited
C-terminal domain of adenylylcyclase associated protein0.006563Inherited
TPR-like1Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.01852Inherited
SET domain1Inherited
Myosin S1 fragment, N-terminal domain0.08402Inherited
HIT/MYND zinc finger-like0.1885Inherited
Zn-dependent exopeptidases1Inherited
TAZ domain0.2554Inherited
Kix domain of CBP (creb binding protein)0.3394Inherited
POZ domain0.6923Inherited
N-terminal domain of cbl (N-cbl)0.002108Inherited
Bromodomain0.4977Inherited
SNF-like0.6728Inherited
RING/U-box1Inherited
Leucine zipper domain1Inherited
Protein kinase-like (PK-like)1Inherited
Acid proteases1Inherited
Cysteine-rich domain0.8007Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    56491,109843
  • 56491 - A heparin-binding domain
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57716,81995
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    81995,57716
  • 81995 - beta-sandwich domain of Sec23/24
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    50985,48065
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.0000000000002029Direct
    47473,57610
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.0000000000005403Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.0000000000006474Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000006257Direct
    48726,57424
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 0.00000000001127Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00000000001447Direct
    54495,54211
  • 54495 - UBC-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.00000000003656Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.0000000001335Direct
    57424,48726
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 0.0000000005075Direct
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.000000001131Direct
    48726,49899
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000136Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000000001544Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00000000209Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.000000005576Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.000000006122Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.0000000164Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000164Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00000002054Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.00000002054Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.00000003678Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00000005133Direct
    47576,47576
  • 47576 - Calponin-homology domain, CH-domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0.00000006656Direct
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.00000006656Direct
    50729,47912
  • 50729 - PH domain-like
  • 47912 - Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
  • 0.00000006656Direct
    57196,57603
  • 57196 - EGF/Laminin
  • 57603 - FnI-like domain
  • 0.00000006656Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0000001299Direct
    47576,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000001375Direct
    48452,144232
  • 48452 - TPR-like
  • 144232 - HIT/MYND zinc finger-like
  • 0.0000003192Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000003313Direct
    57716,46689
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 46689 - Homeodomain-like
  • 0.0000005108Direct
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0000009377Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0.000001043Direct
    50939,50939
  • 50939 - Sialidases
  • 50939 - Sialidases
  • 0.000001124Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00000123Direct
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000001344Direct
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.000001344Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0.000001571Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000005321Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000006189Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000006189Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.000009085Direct
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.00001228Direct
    52335,51556
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.00001258Direct
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.00001411Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.00001876Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.00002388Direct
    144232,82199
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0.0000251Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.00003274Direct
    51045,54534
  • 51045 - WW domain
  • 54534 - FKBP-like
  • 0.00006915Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.00007165Direct
    103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 0.00009642Direct
    81653,81665
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0001002Direct
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.0001011Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0001062Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.0001062Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.0001633Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.0002454Direct
    49265,49899
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0002454Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.0002764Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.0002939Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0003335Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.0003708Direct
    55486,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 0.0003708Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0005122Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.0006081Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0.0006234Direct
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.00063Direct
    52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 0.0008223Direct
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.01916Inherited
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.003388Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.5126Inherited
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0.01852Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.2681Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.001334Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.7106Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.006441Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.5073Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.5073Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.649Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.8045Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.8045Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.7487Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.3444Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.01522Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.00719Inherited
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0.003882Inherited
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0.01033Inherited
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.002328Inherited
    52317,52440
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.002328Inherited
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.002328Inherited
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.002328Inherited
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.02551Inherited
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.008319Inherited
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.104Inherited
    55945,55945
  • 55945 - TATA-box binding protein-like
  • 55945 - TATA-box binding protein-like
  • 0.003159Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.005202Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.0507Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.09713Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.03521Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.03521Inherited
    57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0.09713Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00125Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.02711Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.06968Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.09296Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.1912Inherited
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.1519Inherited
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01852Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.7602Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.01209Inherited
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.06151Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.002856Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0307Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.009279Inherited
    50242,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 0.06151Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.6386Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.02159Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1781Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.3394Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001596Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.002342Inherited
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.07928Inherited
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 1Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.8199Inherited
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.1083Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.3329Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0.9328Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.4475Inherited
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.05609Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.3558Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.02847Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2202Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.005897Inherited
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.001902Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.01262Inherited
    51206,56112
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.01852Inherited
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01852Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.02549Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.9884Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.004467Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.8938Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.4166Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.2841Inherited
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.02131Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.001175Inherited
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0.128Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.2131Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.6463Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.004118Inherited
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0.01356Inherited
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.0507Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.2615Inherited
    46966,50729
  • 46966 - Spectrin repeat
  • 50729 - PH domain-like
  • 0.02743Inherited
    81837,50978
  • 81837 - BEACH domain
  • 50978 - WD40 repeat-like
  • 0.02551Inherited
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0.09713Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0.1403Inherited
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.01209Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.01262Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.02416Inherited
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0.05743Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.1083Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.2465Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.004118Inherited
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.3596Inherited
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 1Inherited
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.4259Inherited
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.4259Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1102Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.587Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.2756Inherited
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 1Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.6678Inherited
    50156,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 0.006563Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.1781Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.00168Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.00168Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.002108Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,57716,46689
  • 81995 - beta-sandwich domain of Sec23/24
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 46689 - Homeodomain-like
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49265,49899,49899
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    48065,50729,82185
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    57424,48726,57424
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    57196,57196,57603
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57603 - FnI-like domain
  • 0Direct
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    50985,48065,50729
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57716,81995,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 81995 - beta-sandwich domain of Sec23/24
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000000000000001898Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000000000007352Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00000000000007234Direct
    100895,47473,57610
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.0000000000004908Direct
    48726,57424,57424
  • 48726 - Immunoglobulin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00000000001127Direct
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000007451Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000012Direct
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000007915Direct
    48726,49899,57196
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00000000136Direct
    48726,48726,49899
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000136Direct
    57424,57424,48726
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 48726 - Immunoglobulin
  • 0.000000001385Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00000000209Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00000000209Direct
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000000002204Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00000000601Direct
    48452,144232,82199
  • 48452 - TPR-like
  • 144232 - HIT/MYND zinc finger-like
  • 82199 - SET domain
  • 0.00000001373Direct
    49265,49265,49899
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000001373Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.0000000164Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000164Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000164Direct
    47576,57716,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00000004991Direct
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.00000006656Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.00000007109Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0000001174Direct
    57414,57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0.0000001375Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000001571Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.0000002178Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0000002197Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0000003534Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000004177Direct
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000005122Direct
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0.0000006711Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.000001344Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000001477Direct
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.00000351Direct
    52335,51556,51338
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.000005637Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.000006189Direct
    57716,57716,46689
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 46689 - Homeodomain-like
  • 0.00001228Direct
    56059,52335,51556
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.00001258Direct
    49899,57196,57184
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00003037Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00003468Direct
    103637,103637,103637
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 103637 - CCHHC domain
  • 0.00005161Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00006088Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00007165Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00008432Direct
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00008432Direct
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001011Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0001062Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.0001062Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0001235Direct
    53300,53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.0001955Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0002789Direct
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0004789Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0006234Direct
    48065,50729,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0008223Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.007265Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.8934Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.1683Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.01102Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.5614Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.5134Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03325Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.8466Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.649Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.01209Inherited
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.1781Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.00719Inherited
    52317,52440,56059
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.002328Inherited
    52021,52317,52440
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.002328Inherited
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0.002328Inherited
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0.002328Inherited
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.002328Inherited
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0.002328Inherited
    82153,82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.00125Inherited
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.09713Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.09713Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.09713Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.01183Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.02549Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00125Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00125Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.05058Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.05058Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.06968Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.5113Inherited
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.07271Inherited
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2044Inherited
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.01209Inherited
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.112Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1291Inherited
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.06151Inherited
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.06151Inherited
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.006563Inherited
    50242,100895,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.06151Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1781Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1781Inherited
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.07928Inherited
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 1Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.7978Inherited
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.1083Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.2948Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.09331Inherited
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.001902Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.4229Inherited
    51206,51206,56112
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.01852Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.6137Inherited
    48726,49265,49899
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.112Inherited
    101912,103575,81296
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0.02551Inherited
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.128Inherited
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.2131Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0507Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.004118Inherited
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.01033Inherited
    46966,46966,50729
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50729 - PH domain-like
  • 0.02743Inherited
    50729,81837,50978
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 50978 - WD40 repeat-like
  • 0.02551Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.01262Inherited
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.02551Inherited
    57196,49854,57196
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.06151Inherited
    49854,49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.06151Inherited
    55486,49854,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.06151Inherited
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.4259Inherited
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.0605Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1102Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.3394Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.002328Inherited
    50156,50729,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.006563Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.00168Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.00168Inherited


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