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Biological Process (BP): regulation of actin filament polymerization

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + + 5:   cellular component organization or biogenesis [GO:0071840] <2>(123|122) (647|619|358)
+ + + + + 5:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ + + + + 5:   regulation of biological quality [GO:0065008] <46>(62|65) (453|402|258)
+ + + + + 5:   regulation of organelle organization [GO:0033043] <27>(20|20) (194|151|67)
+ + + + + 5:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ + + + 4:   cellular component organization [GO:0016043] <33>(113|104) (617|594|349)
+ + + + 4:   regulation of actin filament-based process [GO:0032970] <3>(5|6) (71|50|28)
+ + + + 4:   regulation of anatomical structure size [GO:0090066] <7>(13|12) (133|108|69)
+ + + + 4:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + + 4:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + + + 4:   regulation of cytoskeleton organization [GO:0051493] <6>(8|9) (93|71|36)
+ + + + 4:   single-organism cellular process [GO:0044763] <194>(233|302) (895|984|562)
+ + + 3:   regulation of actin cytoskeleton organization [GO:0032956] <7>(5|6) (61|47|26)
+ + + 3:   regulation of cellular component biogenesis [GO:0044087] <38>(14|14) (160|130|68)
+ + + 3:   regulation of cellular component organization [GO:0051128] <52>(35|32) (311|310|174)
+ + + 3:   regulation of cellular component size [GO:0032535] <12>(10|10) (99|87|55)
+ + 2:   regulation of actin filament length [GO:0030832] <1>(5|6) (38|29|18)
+ + 2:   regulation of protein complex assembly [GO:0043254] <31>(9|9) (78|48|25)
+ + 2:   regulation of supramolecular fiber organization [GO:1902903] <11>(8|8) (72|53|30)
+ 1:   regulation of actin polymerization or depolymerization [GO:0008064] <2>(5|6) (38|29|18)
+ 1:   regulation of protein polymerization [GO:0032271] <7>(6|7) (42|28|18)
0:   regulation of actin filament polymerization [GO:0030833] <4>(4|5) (31|22|15)
- 1:   positive regulation of actin filament polymerization [GO:0030838] <4>(2|2) (10|6|3)
- 1:   regulation of actin nucleation [GO:0051125] <3>(0|0) (5|3|4)
- 1:   negative regulation of actin filament polymerization [GO:0030837] <2>(2|3) (16|7|8)
- 1:   regulation of barbed-end actin filament capping [GO:2000812] <2>(0|0) (2|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 21 kDa subunit ARPC30.0000000000057340.00000000006549Direct
Arp2/3 complex subunits0.00000000001530Direct
Profilin (actin-binding protein)00Direct
Subunits of heterodimeric actin filament capping protein Capz00Direct


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 21 kDa subunit ARPC30.000000000015870.0000000001604Direct
Arp2/3 complex subunits0.000000000034350Direct
Capz alpha-1 subunit0.000000000041260.000000000005217Direct
Capz beta-1 subunit00Direct
Profilin (actin-binding protein)00Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
VHP, Villin headpiece domain0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
DBL homology domain (DH-domain)0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
Profilin (actin-binding protein)0Direct
HR1 repeat0Direct
Arp2/3 complex subunits0Direct
Arp2/3 complex 21 kDa subunit ARPC30.00000000003746Direct
Lipoxigenase0.00000000004935Direct
RNI-like0.000000000439Direct
Arp2/3 complex 16 kDa subunit ARPC50.0000000006318Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.00000009325Direct
SH3-domain0.0000001723Direct
AraD/HMP-PK domain-like0.0000005407Direct
FAT domain of focal adhesion kinase0.000002134Direct
Moesin tail domain0.000008907Direct
Sec7 domain0.00001868Direct
CRAL/TRIO domain0.0002202Direct
NHL repeat0.0003862Direct
Actin depolymerizing proteins0.0004191Direct
Formin homology 2 domain (FH2 domain)0.0006462Direct
Ankyrin repeat1Inherited
SAM/Pointed domain0.01091Inherited
BAR/IMD domain-like0.001966Inherited
PDZ domain-like0.004901Inherited
Protein kinase-like (PK-like)0.6154Inherited
PH domain-like0.01556Inherited
Ubiquitin-like0.0869Inherited
Second domain of FERM0.3293Inherited
Actin-like ATPase domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.00000000000000466Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.00000000000000826Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.00000000000005225Direct
    69645,69645
  • 69645 - Arp2/3 complex subunits
  • 69645 - Arp2/3 complex subunits
  • 0.0000000000001366Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000000001478Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.00000000002042Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0000000002839Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0000000007399Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.000000001294Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000009741Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.00001536Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.00004821Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.00005121Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.000209Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.1158Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    50044,55550,50729
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    55550,50044,55550
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000000000000001898Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0000000000000127Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000000000004729Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000000001478Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000000001478Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0000000002839Direct
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000000052Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000001074Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000002242Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.000005882Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.000006556Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
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