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Biological Process (BP): epithelial cell differentiation

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   biological_process [GO:0008150] <24>
+ + + + 4:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ + + + 4:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
+ + + + 4:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ + + 3:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
+ + + 3:   single-organism cellular process [GO:0044763] <194>(233|302) (895|984|562)
+ + + 3:   single-organism developmental process [GO:0044767] <413>(85|101) (556|628|408)
+ + 2:   cellular developmental process [GO:0048869] <17>(54|55) (410|441|290)
+ + 2:   tissue development [GO:0009888] <29>(31|30) (318|310|205)
+ 1:   cell differentiation [GO:0030154] <91>(51|53) (394|430|283)
+ 1:   epithelium development [GO:0060429] <22>(14|14) (241|223|128)
0:   epithelial cell differentiation [GO:0030855] <25>(6|6) (133|112|74)
- 1:   epithelial cell development [GO:0002064] <11>(2|2) (94|82|56)
- 1:   epithelial cell fate commitment [GO:0072148] <11>(0|0) (9|5|5)
- 1:   epithelial cell differentiation involved in kidney development [GO:0035850] <6>(0|0) (26|19|14)
- 1:   columnar/cuboidal epithelial cell differentiation [GO:0002065] <5>(3|3) (65|47|26)
- 1:   endothelial cell differentiation [GO:0045446] <5>(0|1) (26|22|21)
- 1:   epidermal cell differentiation [GO:0009913] <5>(2|2) (43|28|17)
- 1:   epithelial cell differentiation involved in prostate gland development [GO:0060742] <4>(0|0) (3|2|1)
- 1:   lung epithelial cell differentiation [GO:0060487] <4>(0|0) (0|0|0)
- 1:   mammary gland epithelial cell differentiation [GO:0060644] <3>(1|1) (4|2|2)
- 1:   mesenchymal to epithelial transition [GO:0060231] <3>(0|0) (5|2|0)
- 1:   Sertoli cell differentiation [GO:0060008] <2>(0|1) (6|0|0)
- 1:   epithelial cell differentiation involved in salivary gland development [GO:0060690] <2>(0|0) (0|0|0)
- 1:   granulosa cell differentiation [GO:0060014] <2>(0|0) (1|0|0)
- 1:   leading edge cell differentiation [GO:0035026] <2>(0|0) (1|0|0)
- 1:   lens fiber cell differentiation [GO:0070306] <2>(0|0) (14|15|13)
- 1:   epithelial cell differentiation involved in embryonic placenta development [GO:0060671] <1>(0|0) (0|0|0)
- 1:   multi-ciliated epithelial cell differentiation [GO:1903251] <1>(0|0) (5|2|0)
- 1:   polarized epithelial cell differentiation [GO:0030859] <1>(0|0) (7|12|12)
- 1:   Malpighian tubule principal cell differentiation [GO:0061329](0|0) (0|0|0)
- 1:   Malpighian tubule stellate cell differentiation [GO:0061330](0|0) (2|2|2)
- 1:   cumulus cell differentiation [GO:0001549](0|0) (0|0|0)
- 1:   hepatoblast differentiation [GO:0061017](0|0) (2|0|0)
- 1:   hepatocyte differentiation [GO:0070365](0|0) (3|1|0)
- 1:   respiratory basal cell differentiation [GO:1902691](0|0) (0|0|0)
- 1:   ureter epithelial cell differentiation [GO:0072192](0|0) (1|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cu,Zn superoxide dismutase-like0.000000000016570.00000001892Direct
Trypsin-like serine proteases0.0038380.3695Inherited
HLH, helix-loop-helix DNA-binding domain0.0019060.001005Inherited
Cytokine0.36420.8666Inherited
Homeodomain-like0.010830.1481Inherited
P-loop containing nucleoside triphosphate hydrolases0.083920.09185Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cu,Zn superoxide dismutase-like0.000000000021040.00000002146Direct
Eukaryotic proteases0.0040410.1332Inherited
HLH, helix-loop-helix DNA-binding domain0.0020650.001759Inherited
G proteins0.080461Inherited
Fibroblast growth factors (FGF)0.36480.8959Inherited
Paired domain00.002101Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Intermediate filament protein, coiled coil region0Direct
RILP dimerisation region0.0000000000001996Direct
Geminin coiled-coil domain0.000000000003041Direct
BAR/IMD domain-like0.000000000008568Direct
HR1 repeat0.00000000008163Direct
"Winged helix" DNA-binding domain0.000000004962Direct
Tetraspanin0.00000001027Direct
Cu,Zn superoxide dismutase-like0.00000001156Direct
PDZ domain-like0.0000000193Direct
RGC domain-like0.00000002973Direct
Prefoldin0.00000004872Direct
Second domain of FERM0.00000005734Direct
Ankyrin repeat0.00000006846Direct
HD-domain/PDEase-like0.0000003314Direct
Chromo domain-like0.0000006203Direct
DNA-binding protein LAG-1 (CSL)0.000009753Direct
Ypt/Rab-GAP domain of gyp1p0.0000376Direct
Polo-box domain0.00004832Direct
G protein-binding domain0.00004888Direct
E2F-DP heterodimerization region0.00006248Direct
Dimerization cofactor of HNF-1 alpha0.00007891Direct
Tudor/PWWP/MBT0.00008418Direct
GAF domain-like0.0001028Direct
N-terminal domain of cbl (N-cbl)0.0001142Direct
HMG-box0.0001225Direct
beta-sandwich domain of Sec23/240.0001292Direct
(Phosphotyrosine protein) phosphatases II0.0002395Direct
Ubiquitin-like0.0002775Direct
Nuclear receptor ligand-binding domain0.0003075Direct
Transglutaminase, two C-terminal domains0.000317Direct
BRK domain-like0.0004693Direct
SOCS box-like0.0004791Direct
Stathmin0.0006563Direct
HLH, helix-loop-helix DNA-binding domain0.000716Direct
ARID-like0.0009654Direct
Cyclin-like0.5938Inherited
E set domains0.2815Inherited
Calponin-homology domain, CH-domain0.8465Inherited
WW domain0.0116Inherited
P-loop containing nucleoside triphosphate hydrolases0.07262Inherited
Myosin rod fragments0.1449Inherited
ALDH-like0.5707Inherited
p53-like transcription factors0.3659Inherited
Fibronectin type III1Inherited
GTPase activation domain, GAP0.5506Inherited
SRF-like0.8493Inherited
CAD & PB1 domains0.07819Inherited
Cysteine-rich domain0.6816Inherited
Cystine-knot cytokines1Inherited
N-terminal coiled coil domain from apc0.0022Inherited
Tumor suppressor gene product Apc0.0022Inherited
FAT domain of focal adhesion kinase0.01257Inherited
Integrin domains0.2185Inherited
Integrin alpha N-terminal domain0.5032Inherited
Galactose-binding domain-like1Inherited
SAM/Pointed domain0.7764Inherited
gamma-Crystallin-like0.03294Inherited
Caspase-like0.06836Inherited
Spectrin repeat0.9906Inherited
Immunoglobulin1Inherited
beta-beta-alpha zinc fingers0.8458Inherited
TB module/8-cys domain0.009564Inherited
Growth factor receptor domain0.04046Inherited
Frizzled cysteine-rich domain0.1405Inherited
Notch domain0.003173Inherited
Orange domain-like0.272Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.001514Inherited
SMAD/FHA domain0.006644Inherited
L domain-like1Inherited
Cytokine0.7685Inherited
Cysteine-rich DNA binding domain, (DM domain)0.04737Inherited
Spermadhesin, CUB domain0.8464Inherited
Kringle-like0.236Inherited
FAS1 domain0.3393Inherited
C-type lectin-like0.5931Inherited
Ras GEF0.002343Inherited
cAMP-binding domain-like0.1527Inherited
FAD-linked reductases, C-terminal domain0.7774Inherited
vWA-like0.7275Inherited
STAT0.2923Inherited
ARM repeat1Inherited
Leucine zipper domain0.1639Inherited
Complement control module/SCR domain0.6129Inherited
SH3-domain0.004545Inherited
Acid proteases0.1891Inherited
Plakin repeat0.368Inherited
EGF/Laminin0.6004Inherited
FnI-like domain0.632Inherited
Concanavalin A-like lectins/glucanases1Inherited
F-box domain1Inherited
Protein kinase-like (PK-like)0.9369Inherited
SEA domain0.03598Inherited
TNF receptor-like0.06062Inherited
Cadherin-like0.001412Inherited
Transcription factor STAT-4 N-domain0.5458Inherited
Doublecortin (DC)0.2683Inherited
KA1-like0.02247Inherited
Trypsin-like serine proteases0.309Inherited
GCM domain0.01086Inherited
Zn-finger domain of Sec23/240.03598Inherited
alpha/beta-Hydrolases1Inherited
WD40 repeat-like1Inherited
Heme-dependent peroxidases0.0474Inherited
RNA-binding domain, RBD0.8086Inherited
Kazal-type serine protease inhibitors0.4217Inherited
PYP-like sensor domain (PAS domain)0.7777Inherited
SH2 domain0.2734Inherited
alpha-catenin/vinculin-like0.01512Inherited
Actin depolymerizing proteins0.1331Inherited
SAP domain0.568Inherited
TPR-like0.9657Inherited
Toll/Interleukin receptor TIR domain0.08888Inherited
PH domain-like0.1819Inherited
TRAF domain-like0.287Inherited
Hairpin loop containing domain-like0.01054Inherited
Rap/Ran-GAP0.2055Inherited
lambda repressor-like DNA-binding domains0.1331Inherited
Homeodomain-like0.1189Inherited
DHS-like NAD/FAD-binding domain0.328Inherited
Snake toxin-like0.987Inherited
dsRNA-binding domain-like0.2185Inherited
A DNA-binding domain in eukaryotic transcription factors0.01852Inherited
Kix domain of CBP (creb binding protein)0.00201Inherited
TAZ domain0.007942Inherited
SMAD MH1 domain0.004981Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4146Inherited
A middle domain of Talin 10.00465Inherited
L27 domain0.03598Inherited
I/LWEQ domain0.00201Inherited
CRAL/TRIO domain0.3652Inherited
Blood coagulation inhibitor (disintegrin)0.003776Inherited
LuxS/MPP-like metallohydrolase0.02863Inherited
DEATH domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0Direct
    57184,82153
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 0Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.000000000002002Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.000000000007376Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.00000000008163Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.000000000346Direct
    48403,57903
  • 48403 - Ankyrin repeat
  • 57903 - FYVE/PHD zinc finger
  • 0.000000003055Direct
    56436,82153
  • 56436 - C-type lectin-like
  • 82153 - FAS1 domain
  • 0.000000006401Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.000000007146Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00000001278Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.00000001513Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.00000006404Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00000007507Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000001049Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.000001169Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.000004576Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.000004724Direct
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.000009753Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.000009753Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.00001951Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00002175Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00002667Direct
    82671,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00002756Direct
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.00004888Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.00005399Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.00006248Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.00007891Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.00008919Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.00008967Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.00008967Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.000102Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0001142Direct
    57424,50494
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0.0001429Direct
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0002598Direct
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0.0002836Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0003091Direct
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.000317Direct
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.000317Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0005286Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.0008683Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.06101Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.272Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5941Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.3767Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.6965Inherited
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.00465Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.03705Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.1453Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.1771Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.2267Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.3681Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.903Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.8599Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.003524Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.004928Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.272Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.001967Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.4952Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.5458Inherited
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.2018Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0.6887Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3514Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2923Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.3633Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.2403Inherited
    57603,49265
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.008273Inherited
    57440,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.008273Inherited
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.008273Inherited
    49265,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 0.04737Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.4173Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0.01869Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.4952Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.09846Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.456Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.5458Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.2683Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05164Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.03598Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1658Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.04154Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.009474Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.002239Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.01512Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.5127Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1537Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.07792Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.01086Inherited
    57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0.001077Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.07635Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.1402Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.01504Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.2018Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.00465Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01171Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.05844Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00465Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.00465Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.005487Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01666Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.002409Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.01086Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.07716Inherited
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.01857Inherited
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.02914Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    57184,57184,82153
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 0Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0Direct
    57184,82153,82153
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.00000000000007903Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0000000000007816Direct
    48403,48403,57903
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 57903 - FYVE/PHD zinc finger
  • 0.00000000129Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.000000005644Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000000005707Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.000000007146Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.000000007146Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00000002323Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000002363Direct
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.0000003926Direct
    49899,57196,57184
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0000006818Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000001049Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.000004724Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000009687Direct
    47370,47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.00001906Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00002558Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.00002683Direct
    82671,49854,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00002756Direct
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.00004888Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.00005231Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.00005399Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.00008967Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.00008967Direct
    57424,57424,50494
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0.0001142Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0002646Direct
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.0002836Direct
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.000317Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.000317Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000341Direct
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.0005472Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.4555Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.4796Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00321Inherited
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.007942Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.02914Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.2267Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.2403Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.001063Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.005406Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00766Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.004981Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.3971Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.4952Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.125Inherited
    57440,57440,57603
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.008273Inherited
    57440,57603,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.008273Inherited
    57603,57603,57440
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.008273Inherited
    57603,57603,49265
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.008273Inherited
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.008273Inherited
    49265,57603,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.04737Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.2886Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.02996Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.15Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.993Inherited
    49854,57424,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0022Inherited
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0.0022Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001051Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.5458Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.5946Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4377Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.001077Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00465Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.005487Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01666Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01666Inherited
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.0022Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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