SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): developmental process

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ 1:   biological_process [GO:0008150] <24>
0:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
- 1:   single-organism developmental process [GO:0044767] <413>(85|101) (556|628|408)
- 1:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
- 1:   developmental process involved in reproduction [GO:0003006] <171>(20|22) (213|118|56)
- 1:   anatomical structure formation involved in morphogenesis [GO:0048646] <111>(14|13) (222|184|133)
- 1:   anatomical structure morphogenesis [GO:0009653] <98>(42|40) (377|372|242)
- 1:   dormancy process [GO:0022611] <15>(0|0) (2|0|0)
- 1:   development involved in symbiotic interaction [GO:0044111] <8>(0|0) (0|0|0)
- 1:   abscission [GO:0009838] <6>(0|0) (3|0|0)
- 1:   developmental induction [GO:0031128] <6>(0|0) (4|0|0)
- 1:   maintenance of cell number [GO:0098727] <2>(0|0) (36|29|19)
- 1:   spore germination [GO:0009847] <1>(0|0) (0|0|0)
- 1:   acquisition of mycelium reproductive competence [GO:0097737](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
ARM repeat0.00052160.00000000000006985Direct
Bcl-2 inhibitors of programmed cell death0.0000000040830.00006232Direct
Calponin-homology domain, CH-domain0.00034630Direct
Caspase-like0.00000000018040.0004354Direct
Core binding factor beta, CBF0.000000011790.0000002723Direct
Cu,Zn superoxide dismutase-like0.0000000011990.0008559Direct
Cystine-knot cytokines0.00000051670Direct
Cytokine00Direct
EF-hand0.000032410Direct
HLH, helix-loop-helix DNA-binding domain00Direct
Homeodomain-like0.0000000023510Direct
L domain-like0.00016070Direct
Mitochondrial cytochrome c oxidase subunit VIIb0.0000010130.00007135Direct
p53-like transcription factors0.00011230Direct
PDZ domain-like0.00045660Direct
PHP14-like0.0000000000022530.0000007232Direct
Preprotein translocase SecY subunit0.000000059510.0007782Direct
Protein kinase-like (PK-like)00Direct
Rap/Ran-GAP00.0001438Direct
RNase A-like0.000000002050.0004133Direct
Sema domain0.0000010130Direct
SET domain0.0000016140.000000000009404Direct
Spectrin repeat0.000000095040Direct
Spermadhesin, CUB domain0.00005350Direct
SRF-like0.00025520Direct
Stathmin00Direct
Tubulin C-terminal domain-like0.00046690.00042Direct
VHL0.0000070280.00009379Direct
Family A G protein-coupled receptor-like11Inherited
S-adenosyl-L-methionine-dependent methyltransferases11Inherited
NAD(P)-binding Rossmann-fold domains11Inherited
UBC-like0.20021Inherited
14-3-3 protein0.000001110.005843Inherited
Concanavalin A-like lectins/glucanases0.057720Inherited
Inhibitor of apoptosis (IAP) repeat0.00055030.06617Inherited
GroEL equatorial domain-like0.000033121Inherited
Heme-dependent peroxidases0.011370.00004747Inherited
alpha/beta-Hydrolases11Inherited
Acid proteases0.022041Inherited
(Phosphotyrosine protein) phosphatases II0.25130Inherited
Metallo-dependent phosphatases0.9091Inherited
KRAB domain (Kruppel-associated box)0.97731Inherited
Tropomyosin0.010240.02452Inherited
Troponin coil-coiled subunits0.017870Inherited
(Trans)glycosidases0.060991Inherited
P-loop containing nucleoside triphosphate hydrolases01Inherited
Metallothionein0.086321Inherited
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.00017780.4175Inherited
Annexin0.0000069420.267Inherited
PEBP-like0.0030811Inherited
AF0104/ALDC/Ptd012-like0.042770.1172Inherited
Immunoglobulin0.18510Inherited
Calcium-dependent phosphotriesterase0.98751Inherited
WD40 repeat-like0.000013630.8574Inherited
NagB/RpiA/CoA transferase-like0.035221Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)11Inherited
Integrin alpha N-terminal domain0.0021720Inherited
ALDH-like0.52391Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.00040630.3416Inherited
Lipocalins0.000000000000029080.004664Inherited
Serpins0.000041040.1174Inherited
4-helical cytokines0.0000065440.02278Inherited
POZ domain0.0040490.004239Inherited
Metalloproteases ("zincins"), catalytic domain0.71470.00000000007391Inherited
Aquaporin-like0.00079061Inherited
Ankyrin repeat0.26410.05529Inherited
Radical SAM enzymes11Inherited
Actin depolymerizing proteins0.0000038510.0102Inherited
Fibronectin type III0.0012780Inherited
Mitochondrial carrier0.24521Inherited
Globin-like0.4711Inherited
PX domain0.000033120.008204Inherited
NAP-like0.00082330.3409Inherited
RNA-binding domain, RBD0.074670.01263Inherited
Trypsin-like serine proteases0.018571Inherited
Cysteine proteinases0.000000000059080.01859Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.54931Inherited
eIF4e-like0.46271Inherited
Phospholipase D/nuclease0.0000017070.3296Inherited
beta-beta-alpha zinc fingers0.0037710Inherited
Nucleotide-diphospho-sugar transferases0.69271Inherited
Ubiquitin-like0.03740.000000000005664Inherited
Phosphoglycerate mutase-like11Inherited
Tubulin chaperone cofactor A0.00098040.06473Inherited
Defensin-like0.0030531Inherited
Profilin (actin-binding protein)0.000016060.02164Inherited
Acyl-CoA N-acyltransferases (Nat)11Inherited
Interleukin 8-like chemokines0.000000011750.01972Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Astacin0.00021610.0000004755Direct
B56-like0.00026720.0003834Direct
Bcl-2 inhibitors of programmed cell death0.00000008370.0005536Direct
Bee venom hyaluronidase0.00000000000012780.00000000001768Direct
Calponin-homology domain, CH-domain0.00013850Direct
Caspase catalytic domain0.00000000096680.00008315Direct
Core binding factor beta, CBF0.000000044780.0000008937Direct
Ephrin ectodomain0.00035520.0000000000000627Direct
Fibroblast growth factors (FGF)00Direct
Forkhead DNA-binding domain0.0000017090Direct
G proteins00.00001173Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0.000000030320Direct
HLH, helix-loop-helix DNA-binding domain00Direct
Homeodomain0.0000032080Direct
Integrin alpha N-terminal domain0.0000017090Direct
Janus/Ocnus0.000000000019110.0000004043Direct
Laminin G-like module0.00015350Direct
Mitochondrial cytochrome c oxidase subunit VIIb0.0000017090.0001079Direct
Nuclear receptor0.00024230Direct
Nuclease0.00000033840.000303Direct
Paired domain00Direct
Papain-like00.0005826Direct
Penta-EF-hand proteins0.00020660.0000000007904Direct
Plakophilin 1 helical region0.00063810.000004195Direct
Platelet-derived growth factor-like0.00063810Direct
Protein kinases, catalytic subunit00Direct
Sema domain0.0000017090Direct
Short-chain cytokines0.000000057080.0001465Direct
Spectrin repeat0.0000001790Direct
Spermadhesin, CUB domain0.000091410Direct
SRF-like0.000091410Direct
Stathmin00.00000000000000307Direct
T-box0.00061020Direct
Transforming growth factor (TGF)-beta0.000074640Direct
VHL0.000013640.0001603Direct
Rhodopsin-like11Inherited
UBC-related0.38791Inherited
14-3-3 protein0.000005740.01822Inherited
Inhibitor of apoptosis (IAP) repeat0.0013790.1463Inherited
Ribonuclease A-like0.00000001760.001637Inherited
Galectin (animal S-lectin)0.0010490.0782Inherited
Preprotein translocase SecY subunit0.00000033240.00195Inherited
UDPGT-like0.90451Inherited
Pepsin-like0.0045571Inherited
Extended AAA-ATPase domain0.099711Inherited
Protein serine/threonine phosphatase0.069171Inherited
KRAB domain (Kruppel-associated box)0.98411Inherited
Tropomyosin0.011030.03742Inherited
Troponin I0.030720.1155Inherited
Calmodulin-like0.00044330.7149Inherited
PDZ domain0.0010320Inherited
Cofilin-like0.000027010.002858Inherited
Rap/Ran-GAP00.001395Inherited
Tyrosine-dependent oxidoreductases11Inherited
Metallothionein0.19371Inherited
CAF1-like ribonuclease0.0089630.1017Inherited
CCP-like0.017180.7743Inherited
Plastocyanin/azurin-like0.048111Inherited
Cu,Zn superoxide dismutase-like0.000000015250.003948Inherited
Annexin0.000042610.4661Inherited
Gonadodropin/Follitropin0.030260.8839Inherited
Tubulin, C-terminal domain0.00063810.003264Inherited
Phosphatidylethanolamine binding protein0.0001430.5509Inherited
Germin/Seed storage 7S protein0.1490.826Inherited
AF0104-like0.0012420.01703Inherited
Plant lipid-transfer and hydrophobic proteins0.0000071140.05482Inherited
WD40-repeat0.0006951Inherited
Proteasome subunits11Inherited
Long-chain cytokines0.00018890.0069Inherited
ALDH-like0.77671Inherited
Formate/glycerate dehydrogenases, substrate-binding domain0.00061020.1413Inherited
Serpins0.00050280.3315Inherited
BTB/POZ domain0.002390.00001328Inherited
Isoprenyl diphosphate synthases0.79681Inherited
Aquaporin-like0.0037891Inherited
Ankyrin repeat0.60080.8204Inherited
MoCo biosynthesis proteins0.061791Inherited
Phoshatidylinositol transfer protein, PITP0.000017430.05317Inherited
RUNT domain0.0033440.000000000007781Inherited
Fibronectin type III0.0019090Inherited
Mitochondrial carrier0.65631Inherited
PX domain0.000061450.07117Inherited
Globins0.4681Inherited
NAP-like0.0015870.4997Inherited
IF2B-like0.000000018530.001955Inherited
Retinol binding protein-like0.0000000063950.01062Inherited
Canonical RBD0.10420.1127Inherited
Eukaryotic proteases0.042641Inherited
Translation initiation factor eIF4e0.57921Inherited
Carboxylesterase0.88571Inherited
Classic zinc finger, C2H20.042040.0000000004319Inherited
Ferritin0.02930.9364Inherited
C5 cytosine-specific DNA methylase, DCM0.0060290.00078Inherited
Cofactor-dependent phosphoglycerate mutase0.21640.9685Inherited
Protein prenyltransferases0.017870.7445Inherited
SelR domain0.14710.991Inherited
Tubulin chaperone cofactor A0.0016070.08737Inherited
Arylsulfatase0.27240.002289Inherited
Thioesterases0.0002140.03496Inherited
Defensin0.000000073230.1951Inherited
Profilin (actin-binding protein)0.000064350.04323Inherited
C1 set domains (antibody constant domain-like)0.57971Inherited
Ngr ectodomain-like0.0089630Inherited
Clathrin coat assembly domain0.00015930.2319Inherited
Interleukin 8-like chemokines0.0000004370.1044Inherited
C-type lectin domain0.30290.4548Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Protein kinase-like (PK-like)0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
BAR/IMD domain-like0Direct
Homeodomain-like0Direct
HMG-box0Direct
EF-hand0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Galactose-binding domain-like0Direct
Concanavalin A-like lectins/glucanases0Direct
SH3-domain0Direct
Calponin-homology domain, CH-domain0Direct
L domain-like0Direct
SMAD/FHA domain0Direct
SpoVG-like0Direct
beta-beta-alpha zinc fingers0Direct
PDZ domain-like0Direct
PH domain-like0Direct
Integrin alpha N-terminal domain0Direct
YWTD domain0Direct
Cadherin-like0Direct
FYVE/PHD zinc finger0Direct
Myosin rod fragments0Direct
Fibronectin type III0Direct
Spectrin repeat0Direct
Immunoglobulin0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Troponin coil-coiled subunits0Direct
DBL homology domain (DH-domain)0Direct
Stathmin0Direct
SH2 domain0Direct
Transcription factor STAT-4 N-domain0Direct
Growth factor receptor domain0Direct
Snake toxin-like0Direct
Nuclear receptor ligand-binding domain0Direct
GTPase activation domain, GAP0Direct
Spermadhesin, CUB domain0Direct
SMAD MH1 domain0Direct
Cytokine0Direct
p53-like transcription factors0Direct
Sema domain0Direct
Cystine-knot cytokines0Direct
EGF/Laminin0Direct
SAM/Pointed domain0Direct
SRF-like0Direct
Plexin repeat0Direct
Cysteine-rich domain0Direct
Integrin domains0Direct
Intermediate filament protein, coiled coil region0Direct
FnI-like domain0Direct
TSP-1 type 1 repeat0Direct
LDL receptor-like module0Direct
Frizzled cysteine-rich domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
Second domain of FERM0Direct
STAT0Direct
A heparin-binding domain0Direct
Notch domain0Direct
Heparin-binding domain from vascular endothelial growth factor0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Domain from hypothetical 2610208m17rik protein0Direct
Orange domain-like0Direct
p53 tetramerization domain0Direct
DPY module0Direct
Cysteine-rich DNA binding domain, (DM domain)0.000000000000001898Direct
Hemopexin-like domain0.000000000000003737Direct
TIMP-like0.000000000000009141Direct
Plakin repeat0.00000000000001092Direct
ARM repeat0.00000000000003698Direct
Bromodomain0.0000000000001268Direct
Leucine zipper domain0.0000000000002445Direct
Hedgehog/DD-peptidase0.0000000000004117Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0000000000006343Direct
Tudor/PWWP/MBT0.0000000000008084Direct
Ubiquitin-like0.000000000003158Direct
FAS1 domain0.00000000000496Direct
SET domain0.000000000005286Direct
Hedgehog/intein (Hint) domain0.000000000009643Direct
Midkine0.00000000002126Direct
BRK domain-like0.00000000003422Direct
Nucleoplasmin-like core domain0.00000000003422Direct
Metalloproteases ("zincins"), catalytic domain0.00000000004233Direct
CalX-like0.00000000005388Direct
RILP dimerisation region0.0000000001556Direct
PGBD-like0.0000000001814Direct
C-type lectin-like0.0000000002619Direct
Calpain large subunit, middle domain (domain III)0.0000000002657Direct
DEATH domain0.0000000008838Direct
"Winged helix" DNA-binding domain0.000000001288Direct
Chromo domain-like0.000000001468Direct
Protease propeptides/inhibitors0.000000002884Direct
TAZ domain0.0000000048Direct
Fibrinogen C-terminal domain-like0.00000001133Direct
GAS2 domain-like0.00000001325Direct
PHL pollen allergen0.00000001433Direct
GCM domain0.00000002976Direct
Myosin S1 fragment, N-terminal domain0.00000005294Direct
WW domain0.00000005686Direct
Triple coiled coil domain of C-type lectins0.00000005793Direct
Kringle-like0.00000006419Direct
beta-sandwich domain of Sec23/240.00000007453Direct
DNA-binding pseudobarrel domain0.0000001341Direct
Formin homology 2 domain (FH2 domain)0.0000001675Direct
Core binding factor beta, CBF0.0000001711Direct
Hook domain0.0000002043Direct
Ras GEF0.000000216Direct
Cullin homology domain0.0000002195Direct
Eferin C-derminal domain-like0.0000003718Direct
Kazal-type serine protease inhibitors0.0000003739Direct
NHL repeat0.0000004108Direct
Subtilisin-like0.0000004294Direct
PHP14-like0.0000004606Direct
Chitinase insertion domain0.0000005896Direct
A DNA-binding domain in eukaryotic transcription factors0.0000005993Direct
Methuselah ectodomain0.0000007079Direct
PAZ domain0.0000008343Direct
ARID-like0.000001197Direct
Cyclin-like0.000001791Direct
Kix domain of CBP (creb binding protein)0.000002352Direct
PAH2 domain0.000002415Direct
Geminin coiled-coil domain0.000002473Direct
Nuclear receptor coactivator interlocking domain0.000003345Direct
NAC domain0.000004675Direct
L27 domain0.000007629Direct
TAF(II)230 TBP-binding fragment0.000007791Direct
TAFH domain-like0.000009663Direct
GDNF receptor-like0.0000146Direct
Heme-dependent peroxidases0.00003204Direct
Helical domain of Sec23/240.00003361Direct
DNA-binding protein LAG-1 (CSL)0.00003764Direct
BPTI-like0.0000384Direct
Bcl-2 inhibitors of programmed cell death0.00004227Direct
Mitochondrial cytochrome c oxidase subunit VIIb0.00004852Direct
C-terminal, gelsolin-like domain of Sec23/240.00005553Direct
Granulin repeat0.00005659Direct
VHL0.00006405Direct
E set domains0.00006516Direct
HIT/MYND zinc finger-like0.0000807Direct
Rap/Ran-GAP0.00009887Direct
DNA-binding domain0.0001009Direct
TATA-box binding protein-like0.0001027Direct
Sec7 domain0.0001055Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0.000108Direct
G protein-binding domain0.0001097Direct
CCHHC domain0.0001455Direct
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.0001521Direct
Tetraspanin0.0001817Direct
Dimerization cofactor of HNF-1 alpha0.000193Direct
alpha-catenin/vinculin-like0.0002088Direct
FAT domain of focal adhesion kinase0.0002575Direct
RNase A-like0.0002895Direct
Tubulin C-terminal domain-like0.0002943Direct
I/LWEQ domain0.000299Direct
Caspase-like0.0003054Direct
Cap-Gly domain0.0003056Direct
Zn-finger domain of Sec23/240.0003093Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.0003597Direct
Preprotein translocase SecY subunit0.0005509Direct
Cu,Zn superoxide dismutase-like0.0006071Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.0006448Direct
HAND domain of the nucleosome remodeling ATPase ISWI0.0007021Direct
N-terminal domain of adenylylcyclase associated protein, CAP0.0008112Direct
Lipoxigenase0.0008276Direct
Insulin-like0.0008519Direct
Invertebrate chitin-binding proteins0.0009188Direct
KA1-like0.0009462Direct
UBC-like1Inherited
Ribosomal protein S5 domain 2-like1Inherited
Cystatin/monellin1Inherited
PYP-like sensor domain (PAS domain)0.2064Inherited
FabD/lysophospholipase-like1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
alpha/beta-Hydrolases1Inherited
DNase I-like0.9218Inherited
Peptidylarginine deiminase Pad4, middle domain0.2402Inherited
Pentein1Inherited
B-box zinc-binding domain0.4075Inherited
Nudix1Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
DHH phosphoesterases0.9736Inherited
C-terminal domain of adenylylcyclase associated protein0.03375Inherited
Prismane protein-like0.3235Inherited
Cupredoxins1Inherited
Glutamine synthetase/guanido kinase1Inherited
Arabinanase/levansucrase/invertase1Inherited
14-3-3 protein0.004303Inherited
Translation proteins1Inherited
Calcium-dependent phosphotriesterase1Inherited
Actin-like ATPase domain1Inherited
lambda repressor-like DNA-binding domains0.001575Inherited
IP3 receptor type 1 binding core, domain 20.04935Inherited
MIR domain0.2956Inherited
Eukaryotic type KH-domain (KH-domain type I)0.06942Inherited
DNA/RNA polymerases1Inherited
Chelatase0.9396Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.2847Inherited
Synuclein0.3711Inherited
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30.4427Inherited
CoA-dependent acyltransferases1Inherited
gamma-Crystallin-like0.9425Inherited
Sec2 N-terminal region0.4679Inherited
GroEL-intermediate domain like1Inherited
Single hybrid motif1Inherited
Rudiment single hybrid motif1Inherited
Chicken cartilage matrix protein0.01593Inherited
Assembly domain of cartilage oligomeric matrix protein0.01713Inherited
Ricin B-like lectins1Inherited
Thioredoxin-like1Inherited
vWA-like0.4677Inherited
PUA domain-like1Inherited
V-type ATP synthase subunit C0.1272Inherited
Moesin tail domain0.01641Inherited
TSP type-3 repeat0.1036Inherited
Tubulin chaperone cofactor A0.05061Inherited
Creatinase/aminopeptidase1Inherited
Pseudouridine synthase1Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain1Inherited
PWI domain0.03982Inherited
F1F0 ATP synthase subunit C0.5343Inherited
post-AAA+ oligomerization domain-like1Inherited
Thymidylate synthase/dCMP hydroxymethylase0.4427Inherited
Phoshotransferase/anion transport protein0.9997Inherited
GAF domain-like1Inherited
Acid proteases1Inherited
eIF4e-like1Inherited
SAICAR synthase-like0.288Inherited
TRAF domain-like1Inherited
GroEL apical domain-like1Inherited
S-adenosylmethionine synthetase0.2522Inherited
Dystroglycan, domain 20.003985Inherited
DNA-glycosylase1Inherited
Actin depolymerizing proteins0.007573Inherited
FAD-linked reductases, C-terminal domain1Inherited
ADC-like0.8051Inherited
Cdc48 domain 2-like0.116Inherited
Di-copper centre-containing domain1Inherited
Mib/herc2 domain-like0.02041Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
TNF receptor-like0.01061Inherited
Hect, E3 ligase catalytic domain0.02584Inherited
Crustacean CHH/MIH/GIH neurohormone0.004385Inherited
MAST3 pre-PK domain-like0.0123Inherited
Retrovirus zinc finger-like domains0.9462Inherited
RuBisCo LSMT C-terminal, substrate-binding domain0.5729Inherited
occludin/ELL-like0.08028Inherited
Interleukin 8-like chemokines0.01492Inherited
Tautomerase/MIF0.7237Inherited
Mss4-like1Inherited
Ran binding protein zinc finger-like0.03186Inherited
VPS9 domain0.9113Inherited
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0.8084Inherited
LEA14-like0.6602Inherited
DUSP-like0.2243Inherited
VHP, Villin headpiece domain0.001183Inherited
FAD/NAD(P)-binding domain1Inherited
F1 ATPase inhibitor, IF1, C-terminal domain0.001607Inherited
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.002509Inherited
Smc hinge domain0.08949Inherited
C-terminal domain of PLC-beta1Inherited
Activator of Hsp90 ATPase, Aha10.06799Inherited
Sec1/munc18-like (SM) proteins0.59Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
PRC-barrel domain0.395Inherited
Virus ectodomain0.8216Inherited
Annexin0.2198Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain1Inherited
Glutamine synthetase, N-terminal domain0.1815Inherited
Profilin (actin-binding protein)0.01641Inherited
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.3515Inherited
BRCA2 helical domain0.006287Inherited
BRCA2 tower domain0.006287Inherited
SBT domain0.03016Inherited
Tubulin nucleotide-binding domain-like0.01445Inherited
4-helical cytokines0.0173Inherited
NagB/RpiA/CoA transferase-like1Inherited
Trimeric LpxA-like enzymes1Inherited
AF0104/ALDC/Ptd012-like0.09336Inherited
PEBP-like0.9085Inherited
YhbY-like0.9056Inherited
WRKY DNA-binding domain0.8579Inherited
Bet v1-like0.9727Inherited
SPOC domain-like0.01243Inherited
ArfGap/RecO-like zinc finger0.03477Inherited
Lipocalins0.003421Inherited
C-terminal autoproteolytic domain of nucleoporin nup980.002509Inherited
Rhomboid-like1Inherited
Colipase-like0.06985Inherited
beta-N-acetylhexosaminidase-like domain0.6225Inherited
Connexin430.009313Inherited
E2F-DP heterodimerization region0.00139Inherited
CRAL/TRIO N-terminal domain0.6163Inherited
Nucleotidylyl transferase1Inherited
Class II aaRS and biotin synthetases1Inherited
CCCH zinc finger1Inherited
Ferritin-like1Inherited
Homodimeric domain of signal transducing histidine kinase1Inherited
Aquaporin-like0.9991Inherited
Barwin-like endoglucanases0.02869Inherited
CheY-like1Inherited
Six-hairpin glycosidases1Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases1Inherited
ValRS/IleRS/LeuRS editing domain1Inherited
Arginase/deacetylase0.08947Inherited
ACP-like1Inherited
Acetyl-CoA synthetase-like1Inherited
RING/U-box0.643Inherited
SNF-like1Inherited
Carboxypeptidase regulatory domain-like0.00255Inherited
PP2C-like1Inherited
Carbonic anhydrase0.8647Inherited
Metallothionein0.9777Inherited
RUN domain-like0.7947Inherited
FKBP-like1Inherited
HSP20-like chaperones1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Nucleic acid-binding proteins1Inherited
DNA repair protein MutS, domain III0.7362Inherited
PriA/YqbF domain0.5679Inherited
NAD kinase/diacylglycerol kinase-like1Inherited
BAG domain0.004309Inherited
GINS helical bundle-like0.4875Inherited
ENTH/VHS domain1Inherited
Transglutaminase, two C-terminal domains0.4242Inherited
Insert subdomain of RNA polymerase alpha subunit0.9117Inherited
RBP11-like subunits of RNA polymerase1Inherited
PurM C-terminal domain-like1Inherited
PurM N-terminal domain-like1Inherited
Ribosomal protein S3 C-terminal domain0.7294Inherited
Polo-box domain0.004048Inherited
Formyltransferase0.9829Inherited
Putative isomerase YbhE0.09336Inherited
Retrovirus capsid dimerization domain-like1Inherited
AbfB domain0.5159Inherited
SRCR-like0.00592Inherited
Trypsin-like serine proteases1Inherited
Serine protease inhibitors0.5742Inherited
Doublecortin (DC)0.002258Inherited
Cullin repeat-like0.001563Inherited
SNARE-like1Inherited
(Trans)glycosidases1Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
Riboflavin synthase domain-like1Inherited
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0.696Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain1Inherited
Glycoside hydrolase/deacetylase1Inherited
Band 7/SPFH domain1Inherited
Multidrug resistance efflux transporter EmrE1Inherited
RNA-binding domain, RBD0.009433Inherited
AXH domain0.1962Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase1Inherited
NAP-like0.2841Inherited
Ribosomal proteins S24e, L23 and L15e0.7118Inherited
BAH domain0.0123Inherited
Protein serine/threonine phosphatase 2C, C-terminal domain0.6294Inherited
Kelch motif0.2139Inherited
A middle domain of Talin 10.001147Inherited
POZ domain0.003106Inherited
Putative DNA-binding domain0.04293Inherited
N-terminal domain of cbl (N-cbl)0.183Inherited
HR1 repeat0.001103Inherited
GFP-like0.001576Inherited
Regulator of G-protein signaling, RGS0.001534Inherited
Tumor suppressor gene product Apc0.04595Inherited
N-terminal coiled coil domain from apc0.04595Inherited
Ankyrin repeat0.043Inherited
Alkaline phosphatase-like0.6701Inherited
Activating enzymes of the ubiquitin-like proteins1Inherited
Histone-fold1Inherited
Integrin beta tail domain0.003205Inherited
SNARE fusion complex1Inherited
cAMP-binding domain-like0.004844Inherited
Suppressor of Fused, N-terminal domain0.006287Inherited
Soluble quinoprotein glucose dehydrogenase0.09661Inherited
ALDH-like1Inherited
Galactose oxidase, central domain0.9529Inherited
PX domain0.006061Inherited
t-snare proteins1Inherited
Nucleotide cyclase1Inherited
RCC1/BLIP-II0.02615Inherited
Cytidine deaminase-like1Inherited
FAD-dependent thiol oxidase0.3847Inherited
LigT-like0.138Inherited
Apolipoprotein A-I0.8435Inherited
Type II DNA topoisomerase0.6727Inherited
Tropomyosin0.01866Inherited
HAD-like1Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.6487Inherited
Calcium ATPase, transmembrane domain M0.7478Inherited
Calcium ATPase, transduction domain A0.5911Inherited
CRAL/TRIO domain0.001202Inherited
Cytochrome b5-like heme/steroid binding domain1Inherited
Sigma2 domain of RNA polymerase sigma factors1Inherited
Sigma3 and sigma4 domains of RNA polymerase sigma factors1Inherited
DEK C-terminal domain0.2421Inherited
PR-1-like1Inherited
Globin-like1Inherited
Radical SAM enzymes1Inherited
BEACH domain0.1751Inherited
Zinc beta-ribbon1Inherited
Transferrin receptor-like dimerisation domain0.6989Inherited
FF domain0.5929Inherited
SpoIIaa-like1Inherited
PapD-like0.7252Inherited
Zn-dependent exopeptidases1Inherited
Hairpin loop containing domain-like0.03169Inherited
Periplasmic binding protein-like I1Inherited
Periplasmic binding protein-like II1Inherited
TNF-like0.2233Inherited
Nicotinic receptor ligand binding domain-like0.995Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Ribonuclease PH domain 2-like1Inherited
ACT-like1Inherited
Cytochrome c oxidase subunit E0.08967Inherited
Nucleotidyltransferase1Inherited
GAT-like domain0.9445Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase1Inherited
Complement control module/SCR domain0.5787Inherited
F-box domain1Inherited
DHS-like NAD/FAD-binding domain1Inherited
Thiolase-like1Inherited
Proton glutamate symport protein1Inherited
Clavaminate synthase-like1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
RmlC-like cupins1Inherited
CAD & PB1 domains0.02195Inherited
PA domain1Inherited
RNI-like1Inherited
Multidrug efflux transporter AcrB transmembrane domain0.07255Inherited
Cysteine proteinases0.01404Inherited
Clathrin adaptor appendage domain0.02424Inherited
UBA-like1Inherited
Subdomain of clathrin and coatomer appendage domain0.01919Inherited
Quinoprotein alcohol dehydrogenase-like0.9231Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.9615Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
NTF2-like1Inherited
SWIB/MDM2 domain0.1988Inherited
AhpD-like1Inherited
Voltage-gated potassium channels0.02487Inherited
UDP-glucose/GDP-mannose dehydrogenase C-terminal domain0.1792Inherited
Dihydrofolate reductase-like1Inherited
SAND domain-like0.01053Inherited
MIT domain0.3981Inherited
Pectin lyase-like1Inherited
Plant invertase/pectin methylesterase inhibitor0.54Inherited
Phospholipase A2, PLA20.2527Inherited
EB1 dimerisation domain-like0.4643Inherited
Fzo-like conserved region0.02928Inherited
Fumarate reductase respiratory complex transmembrane subunits1Inherited
CBS-domain pair1Inherited
Cytochrome P4501Inherited
Elafin-like0.3422Inherited
Serpins0.09352Inherited
PRTase-like1Inherited
HMA, heavy metal-associated domain1Inherited
ABC transporter transmembrane region0.009819Inherited
Glycerol-3-phosphate (1)-acyltransferase1Inherited
Seven-hairpin glycosidases1Inherited
HRDC-like0.7223Inherited
Lamin A/C globular tail domain0.2551Inherited
Heme-dependent catalase-like0.6371Inherited
Substrate-binding domain of HMG-CoA reductase0.08493Inherited
NAD-binding domain of HMG-CoA reductase0.08493Inherited
LEM domain0.2521Inherited
Nop domain0.6164Inherited
Mitochondrial carrier1Inherited
C-terminal domain of Ku800.111Inherited
BRCT domain0.3407Inherited
GroEL equatorial domain-like1Inherited
Phospholipase D/nuclease0.2741Inherited
SAP domain0.0205Inherited
Toll/Interleukin receptor TIR domain1Inherited
SOCS box-like0.9633Inherited
Ypt/Rab-GAP domain of gyp1p1Inherited
TPR-like1Inherited
Blood coagulation inhibitor (disintegrin)0.2418Inherited
dsRNA-binding domain-like0.04016Inherited
RNase III domain-like0.776Inherited
Ribonuclease H-like1Inherited
Succinyl-CoA synthetase domains1Inherited
Chaperone J-domain1Inherited
Oxysterol-binding protein-like1Inherited
Nucleoside diphosphate kinase, NDK1Inherited
Subunits of heterodimeric actin filament capping protein Capz0.5081Inherited
GroES-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
WD40 repeat-like0.7593Inherited
Metallo-dependent phosphatases1Inherited
Family A G protein-coupled receptor-like1Inherited
LuxS/MPP-like metallohydrolase1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Defensin-like0.9445Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.0101Inherited
Mago nashi protein0.2685Inherited
SEA domain0.01116Inherited
Sialidases1Inherited
Delta-sleep-inducing peptide immunoreactive peptide0.7718Inherited
Hypothetical protein AF0491, middle domain0.005323Inherited
FYSH domain0.1011Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
PABC (PABP) domain0.005639Inherited
ATP-dependent DNA ligase DNA-binding domain0.7004Inherited
DNA repair protein MutS, domain I0.5268Inherited
MHC antigen-recognition domain1Inherited
MFS general substrate transporter1Inherited
PsbU/PolX domain-like0.7383Inherited
DNA polymerase beta, N-terminal domain-like0.9054Inherited
DNA repair protein MutS, domain II0.7333Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.3232Inherited
HSP40/DnaJ peptide-binding domain1Inherited
Transducin (heterotrimeric G protein), gamma chain0.2217Inherited
GLA-domain0.7302Inherited
PKD domain0.04443Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.23Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain0.1659Inherited
Aspartate/ornithine carbamoyltransferase0.1963Inherited
Carbamoyl phosphate synthetase, large subunit connection domain0.2538Inherited
Methylglyoxal synthase-like0.4503Inherited
Composite domain of metallo-dependent hydrolases0.7424Inherited
Metallo-dependent hydrolases1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
PreATP-grasp domain1Inherited
Class I glutamine amidotransferase-like1Inherited
Hormone receptor domain0.3936Inherited
Prefoldin0.002317Inherited
Alpha-macroglobulin receptor domain0.2458Inherited
Somatomedin B domain0.7628Inherited
Nitric oxide (NO) synthase oxygenase domain0.08552Inherited
Flavoproteins1Inherited
PK beta-barrel domain-like1Inherited
PK C-terminal domain-like0.2535Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
Sec63 N-terminal domain-like0.5676Inherited
Mannose 6-phosphate receptor domain1Inherited
RGC domain-like0.002457Inherited
Anthrax protective antigen0.5985Inherited
Plus3-like0.00441Inherited
HCP-like1Inherited
LeuD/IlvD-like1Inherited
Aconitase iron-sulfur domain1Inherited
Prion-like0.2532Inherited
Leukotriene A4 hydrolase N-terminal domain1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
Thyroglobulin type-1 domain0.002086Inherited
Transducin (alpha subunit), insertion domain0.8988Inherited
The spindle assembly checkpoint protein mad20.1354Inherited
Mannose-binding lectins0.995Inherited
Poly A polymerase C-terminal region-like0.6464Inherited
KRAB domain (Kruppel-associated box)1Inherited
TB module/8-cys domain0.00661Inherited
Inhibitor of apoptosis (IAP) repeat0.05176Inherited
Nucleotide-diphospho-sugar transferases1Inherited
PLC-like phosphodiesterases0.8978Inherited
ThrRS/AlaRS common domain0.7621Inherited
TGS-like1Inherited
Class II aaRS ABD-related1Inherited
HD-domain/PDEase-like1Inherited
Fe,Mn superoxide dismutase (SOD), N-terminal domain0.02072Inherited
Fe,Mn superoxide dismutase (SOD), C-terminal domain0.02681Inherited
ASF1-like0.01954Inherited
Arp2/3 complex subunits0.2073Inherited
Phosphoglycerate mutase-like1Inherited

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