SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): multicellular organism reproduction

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + 2:   biological_process [GO:0008150] <24>
+ 1:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ 1:   reproduction [GO:0000003] <6>(37|41) (304|189|85)
0:   multicellular organism reproduction [GO:0032504] <3>(20|21) (213|135|54)
- 1:   cellular process involved in reproduction in multicellular organism [GO:0022412] <63>(11|9) (148|79|29)
- 1:   multicellular organismal reproductive process [GO:0048609] <23>(11|13) (193|127|53)
- 1:   fusome organization [GO:0045478] <3>(0|0) (1|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.0000054780.0007888Direct
BPTI-like0.00000017360.000004407Direct
Casein kinase II beta subunit0.000035080.0004893Direct
Cu,Zn superoxide dismutase-like0.00000000000022270.0000000000008065Direct
Defensin-like0.0000000000000031440.000000007258Direct
Serpins0.0000000058940.00000003403Direct
Tubulin C-terminal domain-like0.00000067670.000000000006129Direct
Annexin0.03580.1059Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.0010960.05602Inherited
NAD(P)-binding Rossmann-fold domains0.62041Inherited
Cystine-knot cytokines0.000064380.796Inherited
Bcl-2 inhibitors of programmed cell death0.052890.09737Inherited
NagB/RpiA/CoA transferase-like0.039250.02205Inherited
14-3-3 protein0.01080.01197Inherited
ARM repeat0.00017060.05013Inherited
Protein kinase-like (PK-like)0.093680.0604Inherited
Terpenoid synthases0.0041370.2664Inherited
Trypsin-like serine proteases0.0046520.003868Inherited
Cadherin-like0.000000000021810.3993Inherited
Phospholipase D/nuclease0.000000000000031880.04527Inherited


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
AlkB-like0.00000041730.0006081Direct
Casein kinase II beta subunit0.000039850.0006606Direct
Cu,Zn superoxide dismutase-like0.00000000000042450.000000000003377Direct
Defensin00.000000000002432Direct
Gonadodropin/Follitropin0.00000000044930.0000005828Direct
Nuclease0.000000000000004450.00000000004743Direct
Plant lipid-transfer and hydrophobic proteins0.0000016590.000001084Direct
Serpins0.000000014270.00000002562Direct
Small Kunitz-type inhibitors & BPTI-like toxins0.0000070860.0001312Direct
Tubulin, C-terminal domain0.0000010310.00000000000454Direct
Annexin0.041070.1343Inherited
Armadillo repeat0.000000061520.01504Inherited
Nucleosome core histones0.074530.1978Inherited
Tyrosine-dependent oxidoreductases0.69991Inherited
IF2B-like0.019180.00001567Inherited
Bcl-2 inhibitors of programmed cell death0.062920.0853Inherited
14-3-3 protein0.012910.01018Inherited
Protein kinases, catalytic subunit0.12060.07146Inherited
Isoprenyl diphosphate synthases0.0012550.02525Inherited
Eukaryotic proteases0.007240.006539Inherited
G proteins11Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tudor/PWWP/MBT0Direct
Pseudo ankyrin repeat-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
RNA-binding domain, RBD0Direct
dsRNA-binding domain-like0.00000000000002322Direct
Cu,Zn superoxide dismutase-like0.0000000000004384Direct
PAZ domain0.0000000000008541Direct
Chromo domain-like0.000000000001117Direct
Tubulin C-terminal domain-like0.00000000000342Direct
ACT-like0.00000000001453Direct
ABC transporter transmembrane region0.0000000001283Direct
Tubulin nucleotide-binding domain-like0.0000000001844Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.000000003232Direct
Defensin-like0.000000004373Direct
PR-1-like0.000000006131Direct
Serpins0.00000002088Direct
FAS1 domain0.0000002002Direct
Inhibitor of apoptosis (IAP) repeat0.0000004519Direct
MAST3 pre-PK domain-like0.000001694Direct
BPTI-like0.000002876Direct
BAR/IMD domain-like0.00001116Direct
HR1 repeat0.00001405Direct
BRCA2 helical domain0.00002153Direct
BRCA2 tower domain0.00002153Direct
BRK domain-like0.0000221Direct
P-loop containing nucleoside triphosphate hydrolases0.00005309Direct
Tetraspanin0.0001169Direct
PHM/PNGase F0.0001351Direct
The spindle assembly checkpoint protein mad20.0001566Direct
ARID-like0.000226Direct
Casein kinase II beta subunit0.0003436Direct
PYP-like sensor domain (PAS domain)0.0003992Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.000436Direct
POZ domain0.0004765Direct
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin0.0005586Direct
Nucleotide-diphospho-sugar transferases0.2574Inherited
Translation proteins0.9091Inherited
Cupredoxins1Inherited
PHL pollen allergen0.003985Inherited
Glutamine synthetase, N-terminal domain0.005852Inherited
Profilin (actin-binding protein)0.01267Inherited
Barwin-like endoglucanases0.05398Inherited
Annexin0.08408Inherited
Glutamine synthetase/guanido kinase0.3119Inherited
Arabinanase/levansucrase/invertase0.3256Inherited
Aquaporin-like0.5147Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.01356Inherited
14-3-3 protein0.008925Inherited
Thiolase-like1Inherited
GAS2 domain-like0.4209Inherited
EF-hand1Inherited
Calponin-homology domain, CH-domain1Inherited
Nuclear receptor ligand-binding domain0.01719Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.9924Inherited
Complement control module/SCR domain1Inherited
Integrin domains0.7447Inherited
Spectrin repeat0.5802Inherited
G protein-binding domain0.00164Inherited
Cysteine-rich domain0.2386Inherited
YWTD domain0.0152Inherited
Kix domain of CBP (creb binding protein)0.001704Inherited
Eukaryotic type KH-domain (KH-domain type I)0.01081Inherited
SH3-domain0.8544Inherited
DBL homology domain (DH-domain)0.5175Inherited
Phenylalanine zipper0.007487Inherited
A heparin-binding domain0.001689Inherited
CAPPD, an extracellular domain of amyloid beta A4 protein0.004978Inherited
Cadherin-like0.3354Inherited
Colipase-like0.003326Inherited
Regulator of G-protein signaling, RGS0.03265Inherited
(Phosphotyrosine protein) phosphatases II0.4053Inherited
SAM/Pointed domain0.1597Inherited
Cyclin-like0.001735Inherited
Insulin-like0.08621Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.001807Inherited
C-terminal domain of adenylylcyclase associated protein0.003985Inherited
SAICAR synthase-like0.6403Inherited
Myosin S1 fragment, N-terminal domain0.03671Inherited
SpoIIaa-like0.01004Inherited
Cullin repeat-like0.00979Inherited
Succinyl-CoA synthetase domains0.1169Inherited
Glutathione synthetase ATP-binding domain-like0.7858Inherited
UBC-like0.08896Inherited
Oxysterol-binding protein-like0.182Inherited
Nucleoside diphosphate kinase, NDK0.2275Inherited
Phospholipase A2, PLA20.1588Inherited
Rhomboid-like0.2021Inherited
eIF4e-like0.2375Inherited
TAZ domain0.04756Inherited
Nucleoplasmin-like core domain0.4586Inherited
Ubiquitin-like0.7032Inherited
Activating enzymes of the ubiquitin-like proteins0.01444Inherited
E2F-DP heterodimerization region0.01979Inherited
Rap/Ran-GAP0.5355Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.7552Inherited
Protease propeptides/inhibitors1Inherited
Subtilisin-like1Inherited
Homeodomain-like1Inherited
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.01602Inherited
Crisp domain-like0.001807Inherited
Staphylococcal nuclease0.02562Inherited
NAP-like0.03671Inherited
"Winged helix" DNA-binding domain0.6576Inherited
Bet v1-like0.9918Inherited
DNase I-like0.7087Inherited
Voltage-gated potassium channels1Inherited
FYVE/PHD zinc finger0.004799Inherited
Cysteine proteinases1Inherited
C-type lectin-like0.9656Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
beta-beta-alpha zinc fingers0.8628Inherited
Caspase-like0.3659Inherited
CAD & PB1 domains0.8066Inherited
HIT/MYND zinc finger-like0.3093Inherited
FKBP-like0.4184Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
DNA-binding domain1Inherited
Family A G protein-coupled receptor-like1Inherited
Cystine-knot cytokines0.6998Inherited
L domain-like0.4415Inherited
Metalloproteases ("zincins"), catalytic domain0.3907Inherited
PGBD-like0.8259Inherited
Hemopexin-like domain0.9537Inherited
NagB/RpiA/CoA transferase-like0.01673Inherited
Trimeric LpxA-like enzymes0.05946Inherited
Bcl-2 inhibitors of programmed cell death0.07713Inherited
Immunoglobulin1Inherited
Protein kinase-like (PK-like)0.04711Inherited
Fibronectin type III1Inherited
STAT0.4522Inherited
Transcription factor STAT-4 N-domain0.4702Inherited
Putative DNA-binding domain0.00477Inherited
Ribonuclease H-like0.001141Inherited
RING/U-box0.5452Inherited
HMG-box0.09946Inherited
SMAD/FHA domain0.1495Inherited
Histone-fold0.2632Inherited
ARM repeat0.03886Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
Riboflavin synthase domain-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Spermadhesin, CUB domain1Inherited
F-box domain1Inherited
WD40 repeat-like0.1015Inherited
SMAD MH1 domain0.08272Inherited
PDZ domain-like0.7974Inherited
KA1-like0.5654Inherited
RNase III domain-like0.1058Inherited
Toll/Interleukin receptor TIR domain0.8405Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
Zn-dependent exopeptidases1Inherited
alpha/beta-Hydrolases1Inherited
PK C-terminal domain-like0.0986Inherited
PK beta-barrel domain-like0.4272Inherited
Phosphoenolpyruvate/pyruvate domain0.5296Inherited
RmlC-like cupins1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
PABC (PABP) domain0.07462Inherited
Pectin lyase-like0.483Inherited
Terpenoid synthases0.2192Inherited
Ran binding protein zinc finger-like0.8418Inherited
Nuclear receptor coactivator interlocking domain0.1335Inherited
HD-domain/PDEase-like0.8319Inherited
Lysozyme-like0.4225Inherited
(Trans)glycosidases1Inherited
Phospholipase D/nuclease0.035Inherited
Trypsin-like serine proteases0.002827Inherited
Snake toxin-like1Inherited
Heme-dependent peroxidases0.1093Inherited
Kazal-type serine protease inhibitors0.5795Inherited
A middle domain of Talin 10.01267Inherited
Stathmin0.01295Inherited
PH domain-like0.9672Inherited
beta-sandwich domain of Sec23/240.05799Inherited
Ankyrin repeat0.009675Inherited
N-terminal domain of cbl (N-cbl)0.003326Inherited
alpha-catenin/vinculin-like0.1359Inherited
Second domain of FERM0.9986Inherited
A DNA-binding domain in eukaryotic transcription factors0.6714Inherited
I/LWEQ domain0.04756Inherited
Ypt/Rab-GAP domain of gyp1p0.01715Inherited
SOCS box-like0.2946Inherited
L27 domain0.1215Inherited
SH2 domain0.4187Inherited
Blood coagulation inhibitor (disintegrin)0.01238Inherited
Actin depolymerizing proteins0.2251Inherited
CRAL/TRIO domain0.2613Inherited
SAP domain0.5123Inherited
TPR-like0.8008Inherited
Cullin homology domain0.06033Inherited
BRCT domain0.005329Inherited
DNA topoisomerase IV, alpha subunit0.06017Inherited
Chaperone J-domain0.9011Inherited
Multidrug efflux transporter AcrB transmembrane domain0.9402Inherited
Formin homology 2 domain (FH2 domain)0.1713Inherited
Nucleotide cyclase0.1775Inherited
Subunits of heterodimeric actin filament capping protein Capz0.007487Inherited
NAD kinase/diacylglycerol kinase-like0.5088Inherited
TSP-1 type 1 repeat1Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.04359Inherited
Lamin A/C globular tail domain0.007487Inherited
Polo-box domain0.02494Inherited
DNA mismatch repair protein MutL0.005987Inherited
Bromodomain0.1125Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.7888Inherited
Ribosomal protein S5 domain 2-like1Inherited
Cysteine-rich DNA binding domain, (DM domain)0.02937Inherited
lambda repressor-like DNA-binding domains1Inherited
Kelch motif0.9302Inherited
Galactose-binding domain-like1Inherited
Integrin alpha N-terminal domain0.9743Inherited
p53-like transcription factors1Inherited
EGF/Laminin1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    47769,140860
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    47473,88713
  • 47473 - EF-hand
  • 88713 - Glycoside hydrolase/deacetylase
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000000000000006464Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.00000000000002322Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000000006068Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0000000001844Direct
    48403,140860
  • 48403 - Ankyrin repeat
  • 140860 - Pseudo ankyrin repeat-like
  • 0.0000000002527Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.000000003085Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000002151Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.0000008909Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0.000001318Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.000004324Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.00000525Direct
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.00001487Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.00001613Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.00001846Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0000198Direct
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.00002153Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.00002153Direct
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.00002153Direct
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.00002153Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.00002652Direct
    53335,53335
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.00005245Direct
    49562,50729
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 50729 - PH domain-like
  • 0.00006559Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.0001114Direct
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0.0001351Direct
    51161,48371
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.0001351Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000436Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.000436Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0.0004998Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.0008402Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.0009158Direct
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0009322Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.3898Inherited
    50685,49590
  • 50685 - Barwin-like endoglucanases
  • 49590 - PHL pollen allergen
  • 0.003985Inherited
    54368,55931
  • 54368 - Glutamine synthetase, N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0.005852Inherited
    75005,49899
  • 75005 - Arabinanase/levansucrase/invertase
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.03969Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.013Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.846Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.7249Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.09327Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.8944Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.917Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.01295Inherited
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.003326Inherited
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.01295Inherited
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.04756Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.1105Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.3498Inherited
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0.1588Inherited
    57190,57190
  • 57190 - Colipase-like
  • 57190 - Colipase-like
  • 0.003326Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.09076Inherited
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.01602Inherited
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.02714Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.362Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.007384Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.8653Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.02396Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.01408Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.405Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.281Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.01979Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 1Inherited
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.01602Inherited
    55797,57546
  • 55797 - PR-1-like
  • 57546 - Crisp domain-like
  • 0.001807Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.02172Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.02408Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1824Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.01389Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.8097Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.1185Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1435Inherited
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0.002205Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.9666Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.3649Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.3864Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.4469Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01099Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001756Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.3825Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.05453Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.8529Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.2693Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.4958Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.2143Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.3395Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.9212Inherited
    50800,51621
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0.08186Inherited
    51621,52935
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.08229Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.3395Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.155Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.4207Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.9196Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.01267Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.01267Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.003326Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.003326Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.003326Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.1067Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.04186Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.9722Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.08186Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.112Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.9537Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.008386Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.5665Inherited
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.1068Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.7075Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.01508Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01508Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.7279Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.5665Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 1Inherited
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.1283Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.05074Inherited
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0.003326Inherited
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.003326Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.008176Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.009433Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01316Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.02901Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.7378Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.7927Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    48403,47769,140860
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.00000006924Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000002151Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000002151Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000006862Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.000001099Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.000001318Direct
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.00002153Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.00002153Direct
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.00002153Direct
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.00002153Direct
    53448,51161,48371
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.0001351Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0006358Direct
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.0008402Direct
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0009322Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.01194Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.9849Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.9663Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.8326Inherited
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.003326Inherited
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.01295Inherited
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.04756Inherited
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.01602Inherited
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.02714Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.7776Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0582Inherited
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.008176Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.008176Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.009433Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1655Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.1185Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.9458Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.3223Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.4003Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001253Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001756Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.9212Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.2143Inherited
    50800,51621,52935
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.08186Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.3724Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.07043Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.8226Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.01267Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.003326Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.003326Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.04186Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.006679Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.005987Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.7378Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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