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Biological Process (BP): regulation of localization

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + 2:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ 1:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
0:   regulation of localization [GO:0032879] <12>(39|41) (298|273|160)
- 1:   regulation of transport [GO:0051049] <38>(34|35) (239|184|102)
- 1:   regulation of cellular localization [GO:0060341] <22>(14|16) (163|106|54)
- 1:   regulation of cellular component movement [GO:0051270] <6>(11|10) (111|117|83)
- 1:   regulation of protein localization [GO:0032880] <5>(16|17) (152|99|45)
- 1:   regulation of actomyosin contractile ring localization [GO:1901648] <4>(0|0) (0|0|0)
- 1:   regulation of lipid localization [GO:1905952] <4>(5|3) (46|19|11)
- 1:   regulation of sequestering of calcium ion [GO:0051282] <3>(3|2) (30|21|9)
- 1:   regulation of establishment of RNA localization to telomere [GO:1904910] <2>(0|0) (0|0|0)
- 1:   regulation of horizontal cell localization [GO:1902872] <2>(0|0) (0|0|0)
- 1:   regulation of sequestering of zinc ion [GO:0061088] <2>(0|0) (2|1|0)
- 1:   regulation of telomerase RNA localization to Cajal body [GO:1904872] <2>(0|0) (3|2|1)
- 1:   regulation of defense response by callose deposition [GO:2000071](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
4-helical cytokines0.000000000013090Direct
Annexin0.0000000000040330.0000000002262Direct
Cystine-knot cytokines0.000004310Direct
Cytokine0.0002450Direct
DEATH domain0.0000000073630.0003263Direct
Defensin-like0.00000000027240.000007477Direct
EF-hand0.00020780Direct
Insulin-like0.000070940.000000000000007296Direct
Interleukin 8-like chemokines00Direct
Lipocalins0.0000062160.000001056Direct
Metallo-dependent hydrolases0.00000000060910.0005674Direct
PhoU-like00Direct
PX domain0.000032360.00003153Direct
RNase A-like0.000000000015430Direct
Sec1/munc18-like (SM) proteins0.00000042260.000004909Direct
Family A G protein-coupled receptor-like10Inherited
14-3-3 protein0.35140.2765Inherited
Ubiquitin-like0.16060.005172Inherited
FKBP-like0.014690.02246Inherited
Ankyrin repeat0.82280.04459Inherited
WD40 repeat-like11Inherited
Mitochondrial carrier0.28151Inherited
Thioredoxin-like0.033871Inherited
P-loop containing nucleoside triphosphate hydrolases0.0000000000023250.08051Inherited
SNARE fusion complex0.0052130.0000007446Inherited
Protein kinase-like (PK-like)0.74530.000002024Inherited
Bcl-2 inhibitors of programmed cell death0.54850.852Inherited
Immunoglobulin10.004991Inherited
Concanavalin A-like lectins/glucanases0.082320.00001281Inherited
alpha/beta-Hydrolases11Inherited
Aquaporin-like0.052530.8288Inherited
Carbonic anhydrase0.00018340.00277Inherited
Class I glutamine amidotransferase-like0.1631Inherited
RNA-binding domain, RBD0.010781Inherited
(Trans)glycosidases0.0020231Inherited
SNARE-like0.45650.3914Inherited
Cystatin/monellin0.30210.0002985Inherited
Cysteine proteinases0.00085321Inherited
Radical SAM enzymes0.21430.9573Inherited


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Annexin0.0000000000062640.000000002685Direct
Bee venom hyaluronidase00Direct
Defensin0.000000000027530.000000008504Direct
G proteins0.0000000000095640.000000000001635Direct
Gonadodropin/Follitropin0.0000000068210.0000000003541Direct
Insulin-like0.000082290.00000000000002415Direct
Interleukin 8-like chemokines00Direct
Long-chain cytokines00Direct
Ornithine decarboxylase antizyme-like0.000078310.00000000165Direct
PhoU-like00Direct
PX domain0.000051080.0002351Direct
Renal dipeptidase00Direct
Retinol binding protein-like0.0000000010620.0000000003592Direct
Ribonuclease A-like0.000000000020350Direct
Sec1/munc18-like (SM) proteins0.00000070030.00001423Direct
Thioesterases0.0000010070.0000342Direct
Rhodopsin-like0.89590Inherited
Pentraxin (pentaxin)0.000017450.01534Inherited
14-3-3 protein0.35940.2865Inherited
FKBP immunophilin/proline isomerase0.0018270.009557Inherited
Tetratricopeptide repeat (TPR)0.37131Inherited
Interleukin-1 (IL-1)0.025540.000000002235Inherited
WD40-repeat11Inherited
Mitochondrial carrier0.39311Inherited
Interferons/interleukin-10 (IL-10)0.072990.01031Inherited
Thioltransferase0.0019950.1064Inherited
SNARE fusion complex0.0053490.000007491Inherited
Protein kinases, catalytic subunit0.78620.00006181Inherited
Bcl-2 inhibitors of programmed cell death0.5650.8499Inherited
Short-chain cytokines0.95890.8826Inherited
Aquaporin-like0.091110.9079Inherited
Carbonic anhydrase0.00020060.006343Inherited
Ankyrin repeat0.90250.08012Inherited
Ubiquitin-related0.18681Inherited
Calmodulin-like0.14850.0006818Inherited
DJ-1/PfpI0.0087270.1267Inherited
Canonical RBD0.014251Inherited
Arylsulfatase0.042180.000000001429Inherited
Fibroblast growth factors (FGF)0.0015360.00000006583Inherited
Papain-like0.000010760.006961Inherited
MoCo biosynthesis proteins0.000096950.0164Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Plexin repeat0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Cystine-knot cytokines0Direct
Soluble domain of poliovirus core protein 3a0Direct
Cytokine0Direct
SH3-domain0Direct
GTPase activation domain, GAP0Direct
Family A G protein-coupled receptor-like0Direct
RNase A-like0Direct
Interleukin 8-like chemokines0Direct
4-helical cytokines0Direct
Positive stranded ssRNA viruses0Direct
SH2 domain0Direct
PhoU-like0Direct
Sema domain0Direct
EF-hand0Direct
Heparin-binding domain from vascular endothelial growth factor0.000000000000001898Direct
Voltage-gated potassium channels0.000000000000002832Direct
Insulin-like0.000000000000003737Direct
Integrin domains0.00000000000001622Direct
PDZ domain-like0.000000000001329Direct
Integrin beta tail domain0.00000000001512Direct
EGF/Laminin0.00000000005917Direct
Annexin0.0000000001304Direct
IP3 receptor type 1 binding core, domain 20.0000000001836Direct
DNA/RNA polymerases0.000000001663Direct
Metal cation-transporting ATPase, ATP-binding domain N0.000000004118Direct
E set domains0.00000001271Direct
PLC-like phosphodiesterases0.00000009715Direct
Integrin alpha N-terminal domain0.0000001944Direct
Calcium ATPase, transduction domain A0.0000003599Direct
SNARE fusion complex0.0000004744Direct
Zn-finger domain of Sec23/240.0000006351Direct
Rhomboid-like0.0000006554Direct
Lipocalins0.0000006755Direct
C-terminal, gelsolin-like domain of Sec23/240.000000759Direct
MIR domain0.00000112Direct
(Phosphotyrosine protein) phosphatases II0.000001213Direct
Protein kinase-like (PK-like)0.000001306Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.000001471Direct
Calcium ATPase, transmembrane domain M0.000001472Direct
Sec1/munc18-like (SM) proteins0.000003211Direct
YWTD domain0.000003345Direct
BAR/IMD domain-like0.000003997Direct
Defensin-like0.000004923Direct
Lipoxigenase0.000007885Direct
Concanavalin A-like lectins/glucanases0.000008493Direct
RAP domain-like0.00000936Direct
PX domain0.00002118Direct
vWA-like0.0000345Direct
Anaphylotoxins (complement system)0.00003537Direct
Cation efflux protein cytoplasmic domain-like0.00003768Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0.00003882Direct
Class II MHC-associated invariant chain ectoplasmic trimerization domain0.00003883Direct
Growth factor receptor domain0.00003946Direct
Hemopexin-like domain0.00003991Direct
Cap-Gly domain0.00004686Direct
Second domain of FERM0.00005017Direct
Helical domain of Sec23/240.00005418Direct
t-snare proteins0.00005945Direct
beta-sandwich domain of Sec23/240.00007627Direct
Satiety factor CART (cocaine and amphetamine regulated transcript)0.00007761Direct
Viral leader polypeptide zinc finger0.00007761Direct
Spectrin repeat0.0001166Direct
Alkaline phosphatase-like0.0001235Direct
PH domain-like0.0001353Direct
PGBD-like0.0001427Direct
Cystatin/monellin0.0002081Direct
Prion-like0.000217Direct
DEATH domain0.0002277Direct
WW domain0.00023Direct
VPS9 domain0.0003549Direct
Bactericidal permeability-increasing protein, BPI0.0003946Direct
Metallo-dependent hydrolases0.0003997Direct
Mib/herc2 domain-like0.0004071Direct
ERO1-like0.0004071Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0004997Direct
PAH2 domain0.0006387Direct
RCC1/BLIP-II0.0007756Direct
Hect, E3 ligase catalytic domain0.0009771Direct
Cytochrome P4501Inherited
Hormone receptor domain0.3277Inherited
Cysteine-rich domain0.3424Inherited
Homeodomain-like1Inherited
TIMP-like0.04979Inherited
Terpenoid cyclases/Protein prenyltransferases0.6446Inherited
Blood coagulation inhibitor (disintegrin)0.4333Inherited
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.001082Inherited
Cyclophilin-like0.7698Inherited
Composite domain of metallo-dependent hydrolases0.05569Inherited
HR1 repeat0.1448Inherited
FnI-like domain0.1641Inherited
Formin homology 2 domain (FH2 domain)0.178Inherited
Kringle-like0.9571Inherited
beta-beta-alpha zinc fingers1Inherited
FAS1 domain0.3357Inherited
Subtilisin-like0.1873Inherited
SNARE-like0.3284Inherited
FAD/NAD(P)-binding domain1Inherited
GroEL apical domain-like0.2604Inherited
GroEL equatorial domain-like0.2647Inherited
GroEL-intermediate domain like0.5841Inherited
SMAD/FHA domain1Inherited
Myosin S1 fragment, N-terminal domain0.01747Inherited
KA1-like0.9322Inherited
Transducin (alpha subunit), insertion domain0.7364Inherited
Frizzled cysteine-rich domain0.009272Inherited
Hook domain0.08943Inherited
C-type lectin-like0.08929Inherited
Ricin B-like lectins0.001483Inherited
p53 tetramerization domain0.8851Inherited
Peptidase/esterase 'gauge' domain0.01504Inherited
Neurophysin II0.03082Inherited
NTF2-like0.7478Inherited
FYVE/PHD zinc finger1Inherited
Tudor/PWWP/MBT1Inherited
Bromodomain1Inherited
Chromo domain-like1Inherited
RING/U-box1Inherited
lambda repressor-like DNA-binding domains1Inherited
Kelch motif0.357Inherited
Tropomyosin0.6277Inherited
PLP-binding barrel0.3068Inherited
Alanine racemase C-terminal domain-like0.03465Inherited
UBA-like0.6826Inherited
E2F-DP heterodimerization region0.8795Inherited
Multidrug resistance efflux transporter EmrE1Inherited
Mitochondrial carrier1Inherited
L domain-like0.7217Inherited
alpha/beta-Hydrolases1Inherited
Quinoprotein alcohol dehydrogenase-like0.8111Inherited
AhpD-like0.1263Inherited
Doublecortin (DC)0.1071Inherited
Hedgehog/DD-peptidase0.51Inherited
Hedgehog/intein (Hint) domain0.4685Inherited
Cadherin-like0.7403Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.6279Inherited
NHL repeat0.6726Inherited
Carbonic anhydrase0.00201Inherited
Mitochondrial glycoprotein MAM33-like0.001874Inherited
ARM repeat0.4828Inherited
Thyroglobulin type-1 domain0.1148Inherited
Arginase/deacetylase0.2533Inherited
TSP type-3 repeat0.241Inherited
14-3-3 protein0.2279Inherited
Pseudo ankyrin repeat-like0.1451Inherited
Nucleotide cyclase0.947Inherited
MHC antigen-recognition domain1Inherited
Cupredoxins1Inherited
Cation efflux protein transmembrane domain-like0.001201Inherited
TPR-like1Inherited
GAT-like domain0.03017Inherited
ENTH/VHS domain0.04206Inherited
Rap/Ran-GAP0.1062Inherited
N-terminal coiled coil domain from apc0.05586Inherited
Tumor suppressor gene product Apc0.05586Inherited
BRK domain-like0.002569Inherited
Mitotic arrest deficient-like 1, Mad10.008478Inherited
"Winged helix" DNA-binding domain1Inherited
Periplasmic binding protein-like II1Inherited
Nicotinic receptor ligand binding domain-like0.5165Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.79Inherited
Periplasmic binding protein-like I1Inherited
cAMP-binding domain-like0.1722Inherited
POZ domain0.9714Inherited
PYP-like sensor domain (PAS domain)1Inherited
Anthrax protective antigen0.04378Inherited
Fibrinogen coiled-coil and central regions0.002944Inherited
DnaJ/Hsp40 cysteine-rich domain0.1501Inherited
Polo-box domain0.3407Inherited
Nudix1Inherited
Fibronectin type III0.702Inherited
CSL zinc finger0.05586Inherited
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0.03095Inherited
Toll/Interleukin receptor TIR domain0.9027Inherited
Suppressor of Fused, N-terminal domain0.01036Inherited
Ypt/Rab-GAP domain of gyp1p0.00124Inherited
Eferin C-derminal domain-like0.02668Inherited
Flavoproteins0.5267Inherited
Nitric oxide (NO) synthase oxygenase domain0.1571Inherited
Clathrin heavy-chain terminal domain0.004865Inherited
Radical SAM enzymes0.8595Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Myosin rod fragments0.8943Inherited
Ras GEF0.531Inherited
Caspase-like1Inherited
Chitinase insertion domain0.5505Inherited
SRF-like1Inherited
DHS-like NAD/FAD-binding domain0.4913Inherited
Aquaporin-like0.7313Inherited
BRCT domain1Inherited
HMG-box1Inherited
Leucine zipper domain1Inherited
p53-like transcription factors1Inherited
Metallo-dependent phosphatases1Inherited
Alpha-macroglobulin receptor domain0.004393Inherited
Triple coiled coil domain of C-type lectins0.3415Inherited
Tubby C-terminal domain-like0.2012Inherited
Lipovitellin-phosvitin complex, superhelical domain0.005679Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.002021Inherited
I/LWEQ domain0.07862Inherited
Tetraspanin0.5535Inherited
Phospholipase A2, PLA20.3837Inherited
B-box zinc-binding domain0.7915Inherited
NAD kinase/diacylglycerol kinase-like1Inherited
SOCS box-like1Inherited
Trypsin-like serine proteases0.01285Inherited
SRCR-like0.9493Inherited
P-loop containing nucleoside triphosphate hydrolases0.06338Inherited
dsRNA-binding domain-like1Inherited
Connexin430.05321Inherited
Sigma2 domain of RNA polymerase sigma factors0.004248Inherited
Sigma3 and sigma4 domains of RNA polymerase sigma factors0.007007Inherited
Ran binding protein zinc finger-like0.9938Inherited
GLA-domain0.004428Inherited
GAF domain-like0.02943Inherited
HD-domain/PDEase-like0.001206Inherited
DNA-glycosylase0.7346Inherited
TATA-box binding protein-like0.8288Inherited
Thioredoxin-like1Inherited
CCCH zinc finger0.2593Inherited
Seven-hairpin glycosidases0.1768Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
BAG domain0.2592Inherited
Ankyrin repeat0.03445Inherited
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700.7685Inherited
HIN-2000 domain-like0.03388Inherited
WGR domain-like0.06683Inherited
Domain of poly(ADP-ribose) polymerase0.09062Inherited
ABC transporter transmembrane region0.6163Inherited
SAM/Pointed domain0.6611Inherited
Tetracyclin repressor-like, C-terminal domain0.9785Inherited
Class I glutamine amidotransferase-like1Inherited
Bacterial exopeptidase dimerisation domain0.2638Inherited
Moesin tail domain0.02227Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
TNF-like0.193Inherited
Thiolase-like1Inherited
Nuclear receptor ligand-binding domain0.9482Inherited
Zn2/Cys6 DNA-binding domain1Inherited
SCP-like0.07556Inherited
LDL receptor-like module0.2974Inherited
Apolipoprotein A-I0.04075Inherited
Multidrug efflux transporter AcrB transmembrane domain0.1715Inherited
RNA-binding domain, RBD1Inherited
Eukaryotic type KH-domain (KH-domain type I)1Inherited
Actin-like ATPase domain1Inherited
Phospholipase D/nuclease0.03341Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.2391Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.3331Inherited
RUN domain-like0.02139Inherited
Snake toxin-like1Inherited
DNase I-like0.08415Inherited
Bcl-2 inhibitors of programmed cell death0.7542Inherited
P-domain of calnexin/calreticulin0.0069Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.0535Inherited
CalX-like0.9209Inherited
FKBP-like0.01705Inherited
NAD(P)-linked oxidoreductase0.9636Inherited
DPP6 N-terminal domain-like0.007147Inherited
L27 domain0.184Inherited
Acetyl-CoA synthetase-like1Inherited
FabD/lysophospholipase-like1Inherited
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0.00155Inherited
SAP domain1Inherited
Metalloproteases ("zincins"), catalytic domain0.3486Inherited
(Trans)glycosidases1Inherited
VHP, Villin headpiece domain0.005293Inherited
PP2C-like0.0027Inherited
Profilin (actin-binding protein)0.01524Inherited
Fibrinogen C-terminal domain-like0.2281Inherited
Spermadhesin, CUB domain0.02247Inherited
FAT domain of focal adhesion kinase0.002021Inherited
Notch domain0.01077Inherited
Galactose-binding domain-like0.6795Inherited
CAD & PB1 domains0.01583Inherited
TSP-1 type 1 repeat0.6384Inherited
Complement control module/SCR domain0.6861Inherited
SAND domain-like1Inherited
Pectin lyase-like1Inherited
Calpain large subunit, middle domain (domain III)0.05746Inherited
Cysteine proteinases1Inherited
Immunoglobulin0.003665Inherited
GST C-terminal domain-like1Inherited
Zn-dependent exopeptidases1Inherited
WD40 repeat-like1Inherited
F-box domain1Inherited
Outer arm dynein light chain 10.1261Inherited
Invertebrate chitin-binding proteins0.3415Inherited
RNI-like1Inherited
Ubiquitin-like0.003803Inherited
TNF receptor-like0.002148Inherited
C-terminal domain of PLC-beta0.01064Inherited
HAD-like0.7844Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
Riboflavin synthase domain-like1Inherited
Calponin-homology domain, CH-domain0.03781Inherited
Serpins1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    50044,48350
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    48350,55550
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0Direct
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49265,48371
  • 49265 - Fibronectin type III
  • 48371 - ARM repeat
  • 0Direct
    50370,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 0Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    51695,55550
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    63763,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 0Direct
    50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.000000000000001898Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0.0000000000001899Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000000000001948Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000000000001885Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.000000000003625Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.0000000000046Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.00000000001897Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.00000000002466Direct
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.0000000004727Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.000000001933Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.000000002786Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000000004685Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.00000004743Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00000006723Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000006993Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.00000009983Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0000001313Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0000001925Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0000001934Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0000002142Direct
    100909,48371
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 48371 - ARM repeat
  • 0.0000005127Direct
    48403,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 0.0000005127Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0000005303Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.0000006351Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0.0000009561Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.000001853Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.000002288Direct
    81324,51735
  • 81324 - Voltage-gated potassium channels
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.000002578Direct
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.000004318Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.00000936Direct
    47045,47045
  • 47045 - RAP domain-like
  • 47045 - RAP domain-like
  • 0.00000936Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.000009423Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.00001012Direct
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.00001247Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.00001588Direct
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00001817Direct
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.00001817Direct
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.00002122Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.00002532Direct
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.00003537Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.00003598Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.00003802Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00003815Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00003818Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.00003882Direct
    47769,57850
  • 47769 - SAM/Pointed domain
  • 57850 - RING/U-box
  • 0.0000409Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00005351Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00005418Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.00005657Direct
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.00006808Direct
    48592,52029
  • 48592 - GroEL equatorial domain-like
  • 52029 - GroEL apical domain-like
  • 0.00007175Direct
    46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0.00007682Direct
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.00009205Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00009253Direct
    48403,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 0.0001104Direct
    53901,55718
  • 53901 - Thiolase-like
  • 55718 - SCP-like
  • 0.0001104Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.000129Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0001367Direct
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.0001446Direct
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.0001446Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.000171Direct
    63501,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 0.0002353Direct
    48305,57610
  • 48305 - Class II MHC-associated invariant chain ectoplasmic trimerization domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0002353Direct
    56988,81296
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 0.0002353Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.0003166Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0.0003205Direct
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.0003797Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0003968Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0004005Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0004071Direct
    81296,56988
  • 81296 - E set domains
  • 56988 - Anthrax protective antigen
  • 0.0004336Direct
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.0005508Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.0006421Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0006792Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000725Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0008034Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0.0008079Direct
    48239,49410
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 49410 - Alpha-macroglobulin receptor domain
  • 0.0008297Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.0008751Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.0009371Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.4037Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.2442Inherited
    50729,47912
  • 50729 - PH domain-like
  • 47912 - Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
  • 0.001955Inherited
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.00349Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.003451Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01787Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1683Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.4934Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.277Inherited
    52172,52540
  • 52172 - CheY-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.5664Inherited
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.4685Inherited
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.1835Inherited
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.241Inherited
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.241Inherited
    47912,47912
  • 47912 - Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
  • 47912 - Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
  • 0.001955Inherited
    63825,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 0.001265Inherited
    50044,50729
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0.01036Inherited
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.1167Inherited
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.001171Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.08563Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.7943Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.867Inherited
    56436,57196
  • 56436 - C-type lectin-like
  • 57196 - EGF/Laminin
  • 0.007469Inherited
    57196,57535
  • 57196 - EGF/Laminin
  • 57535 - Complement control module/SCR domain
  • 0.03388Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.09062Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.22Inherited
    47370,63748
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.01894Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.4558Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.567Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.5727Inherited
    54277,50156
  • 54277 - CAD & PB1 domains
  • 50156 - PDZ domain-like
  • 0.002363Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.04194Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.1865Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.08135Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.65Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7364Inherited
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.8851Inherited
    50993,53474
  • 50993 - Peptidase/esterase 'gauge' domain
  • 53474 - alpha/beta-Hydrolases
  • 0.007361Inherited
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0.1182Inherited
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.01036Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.1683Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.5186Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 1Inherited
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.002165Inherited
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.5664Inherited
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0.01911Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.8795Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7248Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.003268Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.0174Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.7845Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 1Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.01235Inherited
    159034,57850
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 0.001774Inherited
    57850,159034
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0.001774Inherited
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.006094Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1764Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.4831Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.7286Inherited
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 1Inherited
    81324,47473
  • 81324 - Voltage-gated potassium channels
  • 47473 - EF-hand
  • 0.01036Inherited
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.005679Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.008004Inherited
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.03847Inherited
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.04213Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.9668Inherited
    52058,52200
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.3365Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 1Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.08927Inherited
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.1182Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.005679Inherited
    90229,54928
  • 90229 - CCCH zinc finger
  • 54928 - RNA-binding domain, RBD
  • 0.115Inherited
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.06683Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.3345Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.3637Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.002021Inherited
    81995,49417
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 0.001955Inherited
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0.024Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.8837Inherited
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0.001265Inherited
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.004391Inherited
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0.001812Inherited
    48726,49899
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7999Inherited
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0.07131Inherited
    50989,48371
  • 50989 - Clathrin heavy-chain terminal domain
  • 48371 - ARM repeat
  • 0.004865Inherited
    46785,56112
  • 46785 - "Winged helix" DNA-binding domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0125Inherited
    101288,101288
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0.001955Inherited
    56112,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 0.001955Inherited
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.1182Inherited
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.2203Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.002412Inherited
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.5505Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 1Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.8867Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.4627Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.5535Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.05083Inherited
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.3415Inherited
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.001812Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.1865Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.004328Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.01572Inherited
    51206,56112
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.241Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.9395Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 1Inherited
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.241Inherited
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.8554Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.3415Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00302Inherited
    56112,47473
  • 56112 - Protein kinase-like (PK-like)
  • 47473 - EF-hand
  • 0.2203Inherited
    88946,88659
  • 88946 - Sigma2 domain of RNA polymerase sigma factors
  • 88659 - Sigma3 and sigma4 domains of RNA polymerase sigma factors
  • 0.002434Inherited
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.03388Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.008852Inherited
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.004888Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.05974Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.3142Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.1411Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1752Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.8228Inherited
    52113,142921
  • 52113 - BRCT domain
  • 142921 - WGR domain-like
  • 0.001774Inherited
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0.0192Inherited
    159141,159141
  • 159141 - HIN-2000 domain-like
  • 159141 - HIN-2000 domain-like
  • 0.03388Inherited
    142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.06683Inherited
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.09062Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.5591Inherited
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.59Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.5211Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.001622Inherited
    46689,48498
  • 46689 - Homeodomain-like
  • 48498 - Tetracyclin repressor-like, C-terminal domain
  • 0.9785Inherited
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0.2638Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.005291Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.2949Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01605Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited
    102114,55729
  • 102114 - Radical SAM enzymes
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0.1182Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.1819Inherited
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.1544Inherited
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.3284Inherited
    49899,63887
  • 49899 - Concanavalin A-like lectins/glucanases
  • 63887 - P-domain of calnexin/calreticulin
  • 0.0069Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.9011Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 1Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.1865Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.6485Inherited
    55394,55394
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 55394 - Bactericidal permeability-increasing protein, BPI
  • 0.07087Inherited
    68906,57850
  • 68906 - SAP domain
  • 57850 - RING/U-box
  • 0.05586Inherited
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0107Inherited
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.008754Inherited
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.008754Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.3037Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.02037Inherited
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.003688Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.01172Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.00328Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.007506Inherited
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00201Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 1Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.6678Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.2Inherited
    48403,47031
  • 48403 - Ankyrin repeat
  • 47031 - Second domain of FERM
  • 0.001955Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1729Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.474Inherited
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.002165Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.2126Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.3071Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.1764Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.7773Inherited
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.01499Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.08563Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.001242Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.1732Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    48403,74924,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    50370,56436,56436
  • 50370 - Ricin B-like lectins
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    55550,50044,50729
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0Direct
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,48350,55550
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0Direct
    63763,47095,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    47473,51695,55550
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 0Direct
    55550,55550,56112
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    101912,103575,81296
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    81995,49417,81296
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    51695,55550,55550
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0000000000001047Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000000000001899Direct
    56436,56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.00000000002407Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.00000000007979Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.0000000001131Direct
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.0000000003429Direct
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000000004727Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0000000009157Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.00000002178Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.00000004034Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000004263Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0000001188Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0000002107Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000004736Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0000009571Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.000004735Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.000008859Direct
    47045,47045,47045
  • 47045 - RAP domain-like
  • 47045 - RAP domain-like
  • 47045 - RAP domain-like
  • 0.00000936Direct
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00001817Direct
    46585,46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0.00002001Direct
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.00002122Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00002514Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00003227Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00003281Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.00003802Direct
    63825,57184,63825
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.00003883Direct
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.00003991Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0000409Direct
    48403,52113,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.0000409Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005747Direct
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00007761Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00007791Direct
    48239,49410,50242
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.00009118Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00009253Direct
    53901,53901,55718
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 55718 - SCP-like
  • 0.0001104Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0001287Direct
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.0001446Direct
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.0001446Direct
    63501,57424,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0002353Direct
    56988,81296,81296
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0002353Direct
    57424,57424,56487
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.0002353Direct
    81296,56988,81296
  • 81296 - E set domains
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 0.0002353Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.0002492Direct
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0.0002912Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0003946Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0004071Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0004071Direct
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.0005213Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.0006421Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.0006697Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0006792Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000725Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000725Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.3522Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.01524Inherited
    52172,52540,46689
  • 52172 - CheY-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46689 - Homeodomain-like
  • 0.7313Inherited
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.01787Inherited
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.241Inherited
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.241Inherited
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.1167Inherited
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.1167Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.2998Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.8851Inherited
    56436,57196,57535
  • 56436 - C-type lectin-like
  • 57196 - EGF/Laminin
  • 57535 - Complement control module/SCR domain
  • 0.007469Inherited
    57196,57535,57535
  • 57196 - EGF/Laminin
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.007469Inherited
    55550,50044,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.05586Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.0132Inherited
    57903,47370,63748
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.01894Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.5555Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.006094Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.05588Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.4997Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.04694Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.277Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.6867Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.003268Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.003268Inherited
    159034,57850,159034
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0.001774Inherited
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.01747Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1335Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1764Inherited
    50729,57863,50729
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 0.007469Inherited
    50729,50729,48350
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.01787Inherited
    50729,50729,57863
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.01787Inherited
    75399,75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.02363Inherited
    47986,47986,52540
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01036Inherited
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.02663Inherited
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.03912Inherited
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.1182Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0011Inherited
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.06683Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.002021Inherited
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.009887Inherited
    48726,48726,49899
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7999Inherited
    50989,48371,48371
  • 50989 - Clathrin heavy-chain terminal domain
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.004865Inherited
    56112,101288,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0.001955Inherited
    101288,101288,50156
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.001955Inherited
    50729,49562,48350
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.04694Inherited
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.1182Inherited
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1182Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.2203Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.001085Inherited
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.04194Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01572Inherited
    51206,51206,56112
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.1962Inherited
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.241Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.001371Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2203Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2765Inherited
    52113,142921,47587
  • 52113 - BRCT domain
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.001774Inherited
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.06683Inherited
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1167Inherited
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.59Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1419Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.004009Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00462Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0131Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.1781Inherited
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.1544Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.1136Inherited
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.02792Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.2514Inherited
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.005679Inherited
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0107Inherited
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.07682Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.178Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4315Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.002021Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.005679Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.008754Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1764Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05803Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.1335Inherited
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.004715Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.184Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.184Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.2126Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.6485Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.007683Inherited


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