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Biological Process (BP): regulation of actin filament-based process

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + 2:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ 1:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
0:   regulation of actin filament-based process [GO:0032970] <3>(5|6) (71|50|28)
- 1:   regulation of actin cytoskeleton organization [GO:0032956] <7>(5|6) (61|47|26)
- 1:   regulation of actin filament-based movement [GO:1903115] <5>(0|0) (7|2|1)
- 1:   regulation of actin filament severing [GO:1903918] <2>(0|0) (3|1|1)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Actin depolymerizing proteins0.0000000000000016250Direct
Arp2/3 complex 21 kDa subunit ARPC30.00000000011980.000000007227Direct
Arp2/3 complex subunits0.00000000019350Direct
Profilin (actin-binding protein)00Direct
Subunits of heterodimeric actin filament capping protein Capz00Direct


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 21 kDa subunit ARPC30.00000000031540.00000001394Direct
Arp2/3 complex subunits0.00000000041690Direct
Capz alpha-1 subunit0.0000000025030.0000000009776Direct
Capz beta-1 subunit0.000000002220.000000003286Direct
Cofilin-like0.000000000000004450Direct
Profilin (actin-binding protein)00Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
VHP, Villin headpiece domain0Direct
BAR/IMD domain-like0Direct
SH3-domain0Direct
PH domain-like0Direct
Cysteine-rich domain0Direct
DBL homology domain (DH-domain)0Direct
Myosin rod fragments0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
Profilin (actin-binding protein)0Direct
Formin homology 2 domain (FH2 domain)0Direct
Actin depolymerizing proteins0Direct
Arp2/3 complex subunits0Direct
G protein-binding domain0.000000000000001898Direct
SAM/Pointed domain0.000000000000003737Direct
PDZ domain-like0.0000000000001996Direct
C-terminal, gelsolin-like domain of Sec23/240.000000000001245Direct
GTPase activation domain, GAP0.000000000003436Direct
HR1 repeat0.000000000006523Direct
ARM repeat0.00000000173Direct
Regulator of G-protein signaling, RGS0.000000002271Direct
Arp2/3 complex 21 kDa subunit ARPC30.000000004354Direct
Protein kinase-like (PK-like)0.000000009868Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.00000001198Direct
Moesin tail domain0.00000001339Direct
SH2 domain0.00000001631Direct
Arp2/3 complex 16 kDa subunit ARPC50.00000003319Direct
Second domain of FERM0.00000005372Direct
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.00000006384Direct
Lipoxigenase0.0000002432Direct
Galactose-binding domain-like0.0000004939Direct
DNase I-like0.000001032Direct
RNI-like0.00000392Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000008926Direct
FF domain0.000009732Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.00003186Direct
AraD/HMP-PK domain-like0.00004818Direct
Actin-crosslinking proteins0.00006981Direct
Sec7 domain0.00007703Direct
Thyroglobulin type-1 domain0.0000788Direct
Pseudo ankyrin repeat-like0.0002682Direct
Fibronectin type III0.0004618Direct
RGC domain-like0.0005017Direct
Immunoglobulin0.7623Inherited
Ubiquitin-like0.005343Inherited
FAT domain of focal adhesion kinase0.001941Inherited
Nudix0.1105Inherited
P-loop containing nucleoside triphosphate hydrolases0.3335Inherited
HD-domain/PDEase-like0.05641Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.2044Inherited
Voltage-gated potassium channels0.284Inherited
Calcium ATPase, transduction domain A0.3106Inherited
Calcium ATPase, transmembrane domain M0.3453Inherited
E set domains0.7483Inherited
Ras GEF0.1007Inherited
cAMP-binding domain-like0.5151Inherited
Growth factor receptor domain0.01267Inherited
ArfGap/RecO-like zinc finger0.03275Inherited
Family A G protein-coupled receptor-like1Inherited
Actin-like ATPase domain0.23Inherited
Calponin-homology domain, CH-domain0.005183Inherited
Cystatin/monellin0.00227Inherited
Integrin beta tail domain0.01423Inherited
Ankyrin repeat0.0894Inherited
Frizzled cysteine-rich domain0.1347Inherited
NHL repeat0.02782Inherited
Plexin repeat0.002618Inherited
Sema domain0.005315Inherited
TSP-1 type 1 repeat0.1097Inherited
HAD-like0.4173Inherited
CRAL/TRIO domain0.004225Inherited
Interleukin 8-like chemokines0.1147Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    49265,48371
  • 49265 - Fibronectin type III
  • 48371 - ARM repeat
  • 0Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000000000000001898Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.000000000000002832Direct
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.00000000000000466Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.000000000005589Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.000000000009028Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.00000000002464Direct
    69645,69645
  • 69645 - Arp2/3 complex subunits
  • 69645 - Arp2/3 complex subunits
  • 0.00000000003729Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.00000000007792Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.0000000004353Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.000000001477Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.000000001783Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.000000007993Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000001198Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00000005828Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.0000001057Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000001225Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000004905Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0000005739Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.0000009856Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0.000002473Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.000007965Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.00002707Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0000788Direct
    48371,101447
  • 48371 - ARM repeat
  • 101447 - Formin homology 2 domain (FH2 domain)
  • 0.00008835Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.00008835Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.0001728Direct
    50729,46785
  • 50729 - PH domain-like
  • 46785 - "Winged helix" DNA-binding domain
  • 0.000236Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0002569Direct
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.0005017Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1475Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.03023Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.1928Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.2821Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.01604Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.003525Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.01423Inherited
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.005772Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.01757Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.01491Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.07204Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.03537Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1172Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000000000000001898Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.000000000009028Direct
    50044,55550,50729
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.00000000001545Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00000000007035Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000001783Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000001198Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00000001198Direct
    55550,50044,55550
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00000001404Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00000002629Direct
    55550,50044,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00000004359Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000001233Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000004905Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000004905Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0000005739Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.000001887Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.000007965Direct
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.00001681Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00004726Direct
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00004726Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.00006911Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1092Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.1789Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.04289Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.002401Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.02782Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
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