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Biological Process (BP): cellular protein localization

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   localization [GO:0051179] <10>(91|101) (503|489|298)
+ + 2:   cellular localization [GO:0051641] <12>(36|37) (304|235|116)
+ + 2:   macromolecule localization [GO:0033036] <6>(43|46) (298|213|137)
+ 1:   cellular macromolecule localization [GO:0070727] <4>(19|20) (203|136|73)
+ 1:   protein localization [GO:0008104] <17>(30|31) (246|182|124)
0:   cellular protein localization [GO:0034613] <24>(19|20) (195|134|72)
- 1:   protein localization to organelle [GO:0033365] <21>(14|14) (121|63|22)
- 1:   protein localization to membrane [GO:0072657] <20>(5|4) (69|47|30)
- 1:   intracellular protein transport [GO:0006886] <18>(13|15) (98|56|23)
- 1:   cellular protein complex localization [GO:0034629] <15>(0|0) (8|2|1)
- 1:   protein localization to cell periphery [GO:1990778] <15>(2|2) (30|17|12)
- 1:   maintenance of protein location in cell [GO:0032507] <9>(1|1) (24|17|11)
- 1:   protein localization to cell division site [GO:0072741] <7>(0|0) (1|0|0)
- 1:   protein insertion into membrane [GO:0051205] <5>(0|0) (3|0|0)
- 1:   protein localization to cell tip [GO:1990151] <5>(0|0) (0|0|0)
- 1:   negative regulation of transcription by transcription factor localization [GO:0010621] <1>(0|0) (0|0|0)
- 1:   protein localization to cell surface [GO:0034394] <1>(0|0) (9|5|4)
- 1:   protein localization to juxtaparanode region of axon [GO:0071205] <1>(0|0) (6|6|6)
- 1:   protein localization to trailing edge [GO:0036051] <1>(0|0) (0|0|0)
- 1:   positive regulation of transcription by transcription factor localization [GO:0061586](0|0) (0|0|0)
- 1:   protein localization involved in acrosome reaction [GO:0060476](0|0) (0|0|0)
- 1:   protein localization involved in establishment of planar polarity [GO:0090251](0|0) (0|0|0)
- 1:   protein localization to barrier septum [GO:1902432](0|0) (0|0|0)
- 1:   protein localization to bud neck [GO:0097271](0|0) (0|0|0)
- 1:   protein localization to cell leading edge [GO:1902463](0|0) (1|0|0)
- 1:   protein localization to myelin sheath abaxonal region [GO:0035750](0|0) (0|0|0)
- 1:   protein localization to paranode region of axon [GO:0002175](0|0) (4|5|5)
- 1:   protein localization to pre-autophagosomal structure [GO:0034497](0|0) (0|0|0)
- 1:   protein localization to rhabdomere [GO:1990146](0|0) (0|0|0)
- 1:   regulation of translation by machinery localization [GO:0043143](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Chaperone J-domain0.00064680.00001017Direct
Metallothionein0.0000016370.00003977Direct
NTF2-like0.000040380.0002808Direct
Profilin (actin-binding protein)0.00000006740.000001743Direct
Roadblock/LC7 domain00Direct
Signal recognition particle alu RNA binding heterodimer, SRP9/140.000000001270.0000000003744Direct
Tim10-like0.00068520.0001893Direct
EF-hand0.42850.2385Inherited
P-loop containing nucleoside triphosphate hydrolases0.0031640.6231Inherited
WD40 repeat-like0.0059310.0004178Inherited
Clavaminate synthase-like0.14861Inherited
Preprotein translocase SecE subunit0.084560.07221Inherited
Preprotein translocase SecY subunit0.33690.284Inherited
LexA/Signal peptidase0.95651Inherited
Immunoglobulin0.4661Inherited
Histone-fold0.5250.6283Inherited
4-helical cytokines11Inherited
ARM repeat0.0059070.000000004716Inherited
NAD(P)-linked oxidoreductase0.15760.7218Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
AlkB-like0.00000047870.0001258Direct
Armadillo repeat00.0000000004587Direct
Cell cycle arrest protein BUB30.0000076090.00006587Direct
G proteins0.00035010.0000105Direct
Metallothionein0.0000046490.00006277Direct
NTF2-like0.000000000022440.0006502Direct
Profilin (actin-binding protein)0.00000015820.000002533Direct
Roadblock/LC7 domain00Direct
Signal recognition particle alu RNA binding heterodimer, SRP9/140.0000000023090.0000000005193Direct
Tim10/DDP0.00061840.0001402Direct
Calmodulin-like0.043690.01633Inherited
WD40-repeat0.022030.004347Inherited
Cold shock DNA-binding domain-like0.37990.9802Inherited
Preprotein translocase SecY subunit0.31520.248Inherited
Preprotein translocase SecE subunit0.077220.06166Inherited
Tetratricopeptide repeat (TPR)0.059080.000001618Inherited
Nucleosome core histones0.35410.1371Inherited
Extended AAA-ATPase domain0.0050190.07207Inherited
Interferons/interleukin-10 (IL-10)0.0015340.01353Inherited
Aldo-keto reductases (NADP)0.23380.7595Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Roadblock/LC7 domain0Direct
Cystine-knot cytokines0Direct
FLJ32549 domain-like0Direct
Nucleoporin domain0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
FLJ32549 C-terminal domain-like0Direct
MoeA C-terminal domain-like0.00000000000002495Direct
MoeA N-terminal region -like0.0000000000000387Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.00000000001405Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00000000001502Direct
Molybdenum cofactor biosynthesis proteins0.00000000004364Direct
HR1 repeat0.0000000001192Direct
Mitochondrial import receptor subunit Tom200.0000000002172Direct
Signal recognition particle alu RNA binding heterodimer, SRP9/140.0000000002172Direct
SRP190.0000000003131Direct
WW domain0.0000000004584Direct
ARM repeat0.000000002823Direct
G protein-binding domain0.0000001297Direct
DPP6 N-terminal domain-like0.00000013Direct
FAT domain of focal adhesion kinase0.0000001386Direct
Fzo-like conserved region0.0000001858Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0.0000002007Direct
VPS28 C-terminal domain-like0.0000003281Direct
Lamin A/C globular tail domain0.000001123Direct
Profilin (actin-binding protein)0.000001123Direct
Dystroglycan, domain 20.000002256Direct
Endosomal sorting complex assembly domain0.000003356Direct
LuxS/MPP-like metallohydrolase0.000003716Direct
A middle domain of Talin 10.000004003Direct
Chaperone J-domain0.000006728Direct
TPR-like0.000009442Direct
DnaJ/Hsp40 cysteine-rich domain0.000009564Direct
GLA-domain0.00002376Direct
HSP40/DnaJ peptide-binding domain0.00002584Direct
Metallothionein0.00002678Direct
Calpain large subunit, middle domain (domain III)0.00005082Direct
Tricorn protease domain 20.00005612Direct
Tim10-like0.0001308Direct
Head domain of nucleotide exchange factor GrpE0.0001456Direct
Coiled-coil domain of nucleotide exchange factor GrpE0.0001802Direct
NTF2-like0.0001955Direct
RL5-like0.0002207Direct
WD40 repeat-like0.0002928Direct
Rhomboid-like0.0003343Direct
Prion-like0.0004109Direct
IP3 receptor type 1 binding core, domain 20.000486Direct
MIR domain0.0007734Direct
DUSP-like0.0009405Direct
GAS2 domain-like0.09107Inherited
C-terminal, gelsolin-like domain of Sec23/240.01695Inherited
Helical domain of Sec23/240.02293Inherited
Zn-finger domain of Sec23/240.02293Inherited
beta-sandwich domain of Sec23/240.03415Inherited
BRCT domain0.07306Inherited
P-loop containing nucleoside triphosphate hydrolases0.5373Inherited
HSP20-like chaperones0.3198Inherited
RCC1/BLIP-II0.5313Inherited
HCP-like0.732Inherited
SAM/Pointed domain1Inherited
alpha/beta-Hydrolases1Inherited
Polo-box domain0.1034Inherited
Spectrin repeat0.02676Inherited
SNARE fusion complex0.001646Inherited
Sialidases0.003951Inherited
Sec1/munc18-like (SM) proteins0.9649Inherited
MIT domain0.1034Inherited
PA domain1Inherited
GAT-like domain0.09347Inherited
ENTH/VHS domain0.003521Inherited
t-snare proteins0.1491Inherited
CRAL/TRIO N-terminal domain0.2274Inherited
DEATH domain0.7696Inherited
Tetraspanin1Inherited
vWA-like0.3296Inherited
L27 domain1Inherited
PDZ domain-like1Inherited
CRAL/TRIO domain0.4608Inherited
EF-hand0.1952Inherited
DNase I-like0.08613Inherited
TNF-like0.4782Inherited
Voltage-gated potassium channels0.6247Inherited
Moesin tail domain1Inherited
Signal peptide-binding domain0.1034Inherited
Domain of the SRP/SRP receptor G-proteins0.07655Inherited
Prokaryotic lipoproteins and lipoprotein localization factors0.2542Inherited
SEA domain0.002144Inherited
LDL receptor-like module0.7713Inherited
Kringle-like0.8812Inherited
Growth factor receptor domain1Inherited
RILP dimerisation region0.01252Inherited
Concanavalin A-like lectins/glucanases1Inherited
EGF/Laminin1Inherited
Protein prenylyltransferase0.3426Inherited
Bcl-2 inhibitors of programmed cell death0.07077Inherited
FKBP-like0.8838Inherited
GST C-terminal domain-like0.952Inherited
Cysteine alpha-hairpin motif0.01689Inherited
HD-domain/PDEase-like0.2801Inherited
GroEL apical domain-like0.1431Inherited
GroEL equatorial domain-like0.2507Inherited
GroEL-intermediate domain like0.2955Inherited
PX domain0.1816Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.8274Inherited
beta-beta-alpha zinc fingers1Inherited
Protein kinase-like (PK-like)0.1913Inherited
CCCH zinc finger0.09087Inherited
Fibronectin type III1Inherited
L domain-like1Inherited
PapD-like0.007949Inherited
Mitochondrial carrier1Inherited
Nucleic acid-binding proteins0.2377Inherited
Histone-fold0.5421Inherited
FtsH protease domain-like0.0644Inherited
Frizzled cysteine-rich domain1Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
Formin homology 2 domain (FH2 domain)0.1034Inherited
Preprotein translocase SecE subunit0.05665Inherited
Translation proteins SH3-like domain0.6722Inherited
Phospholipase D/nuclease0.1462Inherited
Kazal-type serine protease inhibitors0.3308Inherited
TIMP-like0.3739Inherited
Nicotinic receptor ligand binding domain-like0.7764Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.8906Inherited
Integrin domains1Inherited
Class I glutamine amidotransferase-like1Inherited
Immunoglobulin1Inherited
DBL homology domain (DH-domain)1Inherited
Ankyrin repeat1Inherited
Calponin-homology domain, CH-domain0.1594Inherited
PH domain-like0.2821Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.7006Inherited
Galactose-binding domain-like0.5509Inherited
BAR/IMD domain-like0.001202Inherited
ArfGap/RecO-like zinc finger0.05686Inherited
POZ domain0.1587Inherited
Ubiquitin-like0.001655Inherited
Kelch motif0.3654Inherited
Second domain of FERM0.01849Inherited
Intermediate filament protein, coiled coil region0.3207Inherited
Toll/Interleukin receptor TIR domain1Inherited
ADP-ribosylation0.1609Inherited
Chromo domain-like0.2989Inherited
Cysteine proteinases0.9051Inherited
Tubby C-terminal domain-like0.004847Inherited
Hect, E3 ligase catalytic domain0.01252Inherited
LexA/Signal peptidase0.9691Inherited
STAT0.01974Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.1034Inherited
Actin-like ATPase domain0.2052Inherited
Preprotein translocase SecY subunit0.2344Inherited
Sec63 N-terminal domain-like0.2542Inherited
EB1 dimerisation domain-like0.04189Inherited
GAF domain-like0.04189Inherited
Transcription factor STAT-4 N-domain0.01359Inherited
Cryptochrome/photolyase FAD-binding domain0.003069Inherited
Cryptochrome/photolyase, N-terminal domain0.008422Inherited
AN1-like Zinc finger0.007529Inherited
Notch domain0.6722Inherited
Domain of poly(ADP-ribose) polymerase0.01034Inherited
WGR domain-like0.01231Inherited
Quinoprotein alcohol dehydrogenase-like0.25Inherited
Actin depolymerizing proteins0.00114Inherited
Cysteine-rich domain0.6512Inherited
alpha-catenin/vinculin-like0.01252Inherited
Cadherin-like0.0618Inherited
I/LWEQ domain0.07655Inherited
UBC-like0.7906Inherited
Orange domain-like0.005518Inherited
YWTD domain0.6239Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Family A G protein-coupled receptor-like1Inherited
UBA-like0.4163Inherited
Ran binding protein zinc finger-like0.02293Inherited
RNA-binding domain, RBD0.4135Inherited
Invasin/intimin cell-adhesion fragments0.005098Inherited
Clathrin adaptor appendage domain0.2498Inherited
SH3-domain0.9642Inherited
ADC-like0.2413Inherited
Cdc48 domain 2-like0.1918Inherited
RING/U-box0.7431Inherited
Mannose 6-phosphate receptor domain0.1918Inherited
E set domains1Inherited
SNARE-like0.001868Inherited
FAD-linked reductases, C-terminal domain0.9932Inherited
SAP domain0.2051Inherited
Clavaminate synthase-like1Inherited
DNA-binding domain0.3159Inherited
4-helical cytokines1Inherited
SH2 domain0.4782Inherited
p53-like transcription factors0.7957Inherited
"Winged helix" DNA-binding domain0.8673Inherited
Fibrinogen C-terminal domain-like0.07655Inherited
Homeodomain-like1Inherited
SIS domain0.2136Inherited
NAD(P)-linked oxidoreductase0.6293Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    50156,64268
  • 50156 - PDZ domain-like
  • 64268 - PX domain
  • 0Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    158548,160651
  • 158548 - FLJ32549 domain-like
  • 160651 - FLJ32549 C-terminal domain-like
  • 0Direct
    53218,63867
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.00000000000002495Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.00000000000003698Direct
    63882,53218
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 0.0000000000000387Direct
    64268,54236
  • 64268 - PX domain
  • 54236 - Ubiquitin-like
  • 0.0000000000001641Direct
    52058,54427
  • 52058 - L domain-like
  • 54427 - NTF2-like
  • 0.0000000000003143Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.000000000001159Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.000000000003409Direct
    54427,46934
  • 54427 - NTF2-like
  • 46934 - UBA-like
  • 0.00000000000383Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00000000001386Direct
    54928,52058
  • 54928 - RNA-binding domain, RBD
  • 52058 - L domain-like
  • 0.00000000002708Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0000000001888Direct
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 0.0000000002477Direct
    50729,90209
  • 50729 - PH domain-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0000000003131Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.0000000006603Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000000001736Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000001736Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.000000002264Direct
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0.00000001442Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.00000002019Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00000004135Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.00000004812Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000007099Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.0000001369Direct
    116846,52540
  • 116846 - MIT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000001791Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.0000001791Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.0000003977Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.0000004882Direct
    53697,53697
  • 53697 - SIS domain
  • 53697 - SIS domain
  • 0.0000005425Direct
    48464,57903
  • 48464 - ENTH/VHS domain
  • 57903 - FYVE/PHD zinc finger
  • 0.000001194Direct
    47576,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000001194Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.000001491Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.000001502Direct
    49313,111006
  • 49313 - Cadherin-like
  • 111006 - Dystroglycan, domain 2
  • 0.000002256Direct
    50978,48452
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0.000002256Direct
    50242,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000002429Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.000003904Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.000003929Direct
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.000004003Direct
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.000005367Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.000005818Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000006035Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.00000604Direct
    140111,140427
  • 140111 - Endosomal sorting complex assembly domain
  • 140427 - VPS28 C-terminal domain-like
  • 0.000006427Direct
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.000007442Direct
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0.000009306Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.000009964Direct
    50978,69322
  • 50978 - WD40 repeat-like
  • 69322 - Tricorn protease domain 2
  • 0.00001465Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00001484Direct
    46565,158702
  • 46565 - Chaperone J-domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.00001484Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00001698Direct
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0.00002114Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.00003729Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.00006534Direct
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.00006996Direct
    58014,51064
  • 58014 - Coiled-coil domain of nucleotide exchange factor GrpE
  • 51064 - Head domain of nucleotide exchange factor GrpE
  • 0.0001456Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.0003356Direct
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000613Direct
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0009835Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.3706Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.02293Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.02293Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.8775Inherited
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.1884Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.1034Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.6164Inherited
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0.02092Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.1034Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.007795Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.009442Inherited
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.382Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.6868Inherited
    52540,47446
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47446 - Signal peptide-binding domain
  • 0.1034Inherited
    47364,52540
  • 47364 - Domain of the SRP/SRP receptor G-proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.07655Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.6164Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.6164Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.7061Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001428Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.9884Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.6529Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.3426Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.2887Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.4506Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.01689Inherited
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0.04689Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.004138Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.7532Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.8802Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.2542Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.005056Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.003221Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.05182Inherited
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.1034Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.02249Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.1148Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.1034Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.01499Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.01572Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.03098Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.07226Inherited
    50249,46785
  • 50249 - Nucleic acid-binding proteins
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1034Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.02046Inherited
    63825,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 0.2542Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.01293Inherited
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0.007065Inherited
    142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.005098Inherited
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.009442Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.002161Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.01252Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.3018Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.3426Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.005174Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.2653Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 1Inherited
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.004538Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.2413Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3039Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0.9419Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1046Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.8908Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.4608Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.8479Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.07655Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    50156,64268,54236
  • 50156 - PDZ domain-like
  • 64268 - PX domain
  • 54236 - Ubiquitin-like
  • 0Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.00000000000001446Direct
    63882,53218,63867
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.00000000000002495Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0000000000005903Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.000000000003096Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.000000000005221Direct
    54928,52058,54427
  • 54928 - RNA-binding domain, RBD
  • 52058 - L domain-like
  • 54427 - NTF2-like
  • 0.00000000001544Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00000000006519Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.00000000007566Direct
    52058,54427,46934
  • 52058 - L domain-like
  • 54427 - NTF2-like
  • 46934 - UBA-like
  • 0.0000000008852Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000000001736Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000001736Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000001736Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000000002264Direct
    57184,57184,63825
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.00000001323Direct
    63825,57184,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00000001323Direct
    50978,50978,48452
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0.00000001323Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.00000003455Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000007099Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000007099Direct
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000002279Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000002279Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000003977Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.0000003977Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000004795Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0000005245Direct
    47576,57716,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000005654Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.000001048Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000002429Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000002429Direct
    50242,100895,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000002429Direct
    64268,50044,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.000002846Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.000003356Direct
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.000004003Direct
    50729,57863,48403
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.00001661Direct
    47364,52540,47446
  • 47364 - Domain of the SRP/SRP receptor G-proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47446 - Signal peptide-binding domain
  • 0.00002759Direct
    103657,50729,57863
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.00007284Direct
    90209,90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0001615Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002207Direct
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000257Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0003018Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0003209Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3706Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2542Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5814Inherited
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.05665Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.382Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.1394Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.3746Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.7061Inherited
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7061Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.7061Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.1394Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.4429Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.7532Inherited
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.002036Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1351Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.1034Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.001694Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.01051Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.01293Inherited
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.004538Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.01695Inherited
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.1034Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.05686Inherited
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1394Inherited
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.8175Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 1Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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