SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Biological Process (BP): tube morphogenesis

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ + + 3:   biological_process [GO:0008150] <24>
+ + + 3:   single-multicellular organism process [GO:0044707] <74>(83|99) (548|635|419)
+ + 2:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
+ + 2:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
+ + 2:   multicellular organism development [GO:0007275] <28>(76|90) (505|574|376)
+ + 2:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ 1:   anatomical structure morphogenesis [GO:0009653] <98>(42|40) (377|372|242)
+ 1:   single-organism developmental process [GO:0044767] <413>(85|101) (556|628|408)
+ 1:   tube development [GO:0035295] <26>(6|8) (184|143|80)
0:   tube morphogenesis [GO:0035239] <12>(5|4) (145|122|74)
- 1:   epithelial tube morphogenesis [GO:0060562] <11>(3|3) (139|115|69)
- 1:   digestive tract morphogenesis [GO:0048546] <8>(1|1) (24|10|3)
- 1:   branching morphogenesis of an epithelial tube [GO:0048754] <7>(2|2) (48|32|15)
- 1:   tube formation [GO:0035148] <5>(0|0) (51|30|15)
- 1:   semicircular canal morphogenesis [GO:0048752] <2>(1|0) (8|8|5)
- 1:   ureter morphogenesis [GO:0072197] <2>(0|0) (2|0|0)
- 1:   bronchus morphogenesis [GO:0060434] <1>(0|0) (0|0|0)
- 1:   tube fusion [GO:0035146] <1>(0|0) (11|8|4)
- 1:   bronchiole morphogenesis [GO:0060436](0|0) (0|0|0)
- 1:   cloacal septation [GO:0060197](0|0) (0|0|0)
- 1:   oviduct morphogenesis [GO:0035848](0|0) (0|0|0)
- 1:   tracheal outgrowth, open tracheal system [GO:0007426](0|0) (3|1|2)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cytokine00.000000000000114Direct
POZ domain0.0000019310.000002885Direct
HLH, helix-loop-helix DNA-binding domain0.00038760.01183Inherited
Cysteine proteinases0.0000000045230.593Inherited
EF-hand0.45260.000383Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
BTB/POZ domain0.0000011820.00000002902Direct
Fibroblast growth factors (FGF)00.00000000000006009Direct
Papain-like0.00000000076830.000007409Direct
HLH, helix-loop-helix DNA-binding domain0.00022150.01809Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAS2 domain-like0Direct
DPY module0Direct
DBL homology domain (DH-domain)0.0000000000000127Direct
Cytokine0.00000000000006066Direct
Plakin repeat0.0000000000001577Direct
HMG-box0.0000000000001706Direct
Putative DNA-binding domain0.00000000000222Direct
HR1 repeat0.00000000001102Direct
SH3-domain0.000000000226Direct
Homeodomain-like0.0000000008992Direct
Kelch motif0.000000003561Direct
SAND domain-like0.00000000448Direct
beta-sandwich domain of Sec23/240.00000000977Direct
beta-beta-alpha zinc fingers0.00000001169Direct
GTPase activation domain, GAP0.00000002553Direct
Spermadhesin, CUB domain0.00000005234Direct
Growth factor receptor domain0.0000001211Direct
BRK domain-like0.0000001439Direct
Zn-finger domain of Sec23/240.000000235Direct
BAR/IMD domain-like0.0000005833Direct
EGF/Laminin0.000001173Direct
POZ domain0.000001871Direct
Glucocorticoid receptor-like (DNA-binding domain)0.000003639Direct
Frizzled cysteine-rich domain0.000003722Direct
SPOC domain-like0.000012Direct
SMAD MH1 domain0.00002001Direct
Heparin-binding domain from vascular endothelial growth factor0.00003686Direct
PH domain-like0.00004076Direct
Cadherin-like0.00004428Direct
Formin homology 2 domain (FH2 domain)0.00004836Direct
PDZ domain-like0.00009146Direct
Helical domain of Sec23/240.0001029Direct
G protein-binding domain0.0001097Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0.0001931Direct
N-terminal domain of cbl (N-cbl)0.0001931Direct
EF-hand0.000268Direct
ThrRS/AlaRS common domain0.0003198Direct
Metal cation-transporting ATPase, ATP-binding domain N0.0004542Direct
Protein kinase-like (PK-like)0.0004818Direct
FnI-like domain0.0005947Direct
V-type ATP synthase subunit C0.0006314Direct
N-terminal coiled coil domain from apc0.0006314Direct
Tumor suppressor gene product Apc0.0006314Direct
C-terminal, gelsolin-like domain of Sec23/240.000703Direct
Cystine-knot cytokines0.0009981Direct
Hedgehog/DD-peptidase0.01669Inherited
Hedgehog/intein (Hint) domain0.0302Inherited
Cullin homology domain0.1181Inherited
Cullin repeat-like0.1303Inherited
A DNA-binding domain in eukaryotic transcription factors0.1855Inherited
SMAD/FHA domain0.09539Inherited
ALDH-like0.3472Inherited
"Winged helix" DNA-binding domain0.7458Inherited
Fibronectin type III1Inherited
Snake toxin-like0.09207Inherited
SRF-like0.03794Inherited
Midkine0.003117Inherited
TGS-like0.001422Inherited
Troponin coil-coiled subunits0.0173Inherited
IP3 receptor type 1 binding core, domain 20.004721Inherited
DNA-binding protein LAG-1 (CSL)0.03579Inherited
Cysteine proteinases0.5096Inherited
Fibrinogen C-terminal domain-like0.5658Inherited
Nuclear receptor ligand-binding domain0.667Inherited
SAM/Pointed domain0.2363Inherited
Galactose-binding domain-like0.3759Inherited
SOCS box-like0.05689Inherited
Bet v1-like0.2164Inherited
Immunoglobulin1Inherited
HLH, helix-loop-helix DNA-binding domain0.00882Inherited
TRAF domain-like0.1993Inherited
PP2C-like0.3776Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
Leucine zipper domain0.879Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
Calcium-dependent phosphotriesterase0.1134Inherited
C-type lectin-like0.7505Inherited
Cyclin-like0.7915Inherited
WD40 repeat-like0.1407Inherited
alpha/beta-Hydrolases1Inherited
ARM repeat0.7894Inherited
Acid proteases0.4669Inherited
Complement control module/SCR domain0.8794Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.7865Inherited
Sec7 domain0.07523Inherited
Moesin tail domain0.004721Inherited
L domain-like0.3418Inherited
Spectrin repeat0.002725Inherited
Calponin-homology domain, CH-domain0.01275Inherited
PYP-like sensor domain (PAS domain)0.1759Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Thyroglobulin type-1 domain0.06774Inherited
Serine protease inhibitors0.001173Inherited
Calcium ATPase, transmembrane domain M0.001875Inherited
Calcium ATPase, transduction domain A0.002858Inherited
HAD-like0.02013Inherited
Kazal-type serine protease inhibitors0.1485Inherited
Second domain of FERM0.02341Inherited
BRCT domain0.05497Inherited
RNA-binding domain, RBD0.03231Inherited
FKBP-like0.4812Inherited
WW domain0.4901Inherited
PGBD-like0.001749Inherited
Hemopexin-like domain0.001749Inherited
Ankyrin repeat0.00853Inherited
SH2 domain0.457Inherited
CCHHC domain0.003083Inherited
A middle domain of Talin 10.001068Inherited
I/LWEQ domain0.003376Inherited
alpha-catenin/vinculin-like0.1432Inherited
Metalloproteases ("zincins"), catalytic domain0.1423Inherited
Regulator of G-protein signaling, RGS0.01125Inherited
KA1-like0.05005Inherited
Cysteine-rich domain0.002555Inherited
Ras GEF0.5138Inherited
Bromodomain0.7142Inherited
Quinoprotein alcohol dehydrogenase-like0.123Inherited
Chromo domain-like0.1464Inherited
Integrin domains1Inherited
Protease propeptides/inhibitors0.8564Inherited
Kringle-like0.5154Inherited
Subtilisin-like0.9278Inherited
p53-like transcription factors0.002073Inherited
NTF2-like0.09755Inherited
Dihydrofolate reductase-like0.01606Inherited
Glycerol-3-phosphate (1)-acyltransferase0.1683Inherited
DNA-binding domain0.6321Inherited
Voltage-gated potassium channels0.9435Inherited
Notch domain0.008162Inherited
SET domain1Inherited
LDL receptor-like module1Inherited
Clavaminate synthase-like1Inherited
Ubiquitin-like0.1156Inherited
vWA-like0.1781Inherited
Aminoacid dehydrogenase-like, N-terminal domain0.2432Inherited
HIT/MYND zinc finger-like0.3166Inherited
DEATH domain0.3392Inherited
TIMP-like0.008288Inherited
CAD & PB1 domains0.2134Inherited
Nucleotide-diphospho-sugar transferases0.7176Inherited
Class II aaRS ABD-related0.03559Inherited
Class II aaRS and biotin synthetases0.1839Inherited
TSP-1 type 1 repeat0.3829Inherited
Plexin repeat0.2862Inherited
Sema domain0.299Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    57184,90148
  • 57184 - Growth factor receptor domain
  • 90148 - DPY module
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.000000000000001898Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0.000000000000001898Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.000000000000152Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00000000002417Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.000000005463Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000001429Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000009348Direct
    55486,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 0.0000001209Direct
    51905,47576
  • 51905 - FAD/NAD(P)-binding domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0.0000001629Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.0000001629Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.000000235Direct
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.0000003613Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0000004292Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.000000851Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0.000001072Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000001509Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000002226Direct
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.000003209Direct
    55186,55681
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.000004088Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000005561Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00001812Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.00001821Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.00002805Direct
    54534,47473
  • 54534 - FKBP-like
  • 47473 - EF-hand
  • 0.00003253Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00003477Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00006054Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00007348Direct
    54277,50156
  • 54277 - CAD & PB1 domains
  • 50156 - PDZ domain-like
  • 0.00007802Direct
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0.00008182Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.00009161Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0001029Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.0001386Direct
    48592,52029
  • 48592 - GroEL equatorial domain-like
  • 52029 - GroEL apical domain-like
  • 0.0001516Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0001518Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.0001518Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.0001758Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0001931Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.0001931Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0002884Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.0003312Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0003454Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.0003524Direct
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0005399Direct
    48350,54236
  • 48350 - GTPase activation domain, GAP
  • 54236 - Ubiquitin-like
  • 0.0006314Direct
    81324,47473
  • 81324 - Voltage-gated potassium channels
  • 47473 - EF-hand
  • 0.0006314Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0006949Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.001957Inherited
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.01414Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.05005Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.08486Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.03081Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.6918Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.06774Inherited
    49265,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 0.01305Inherited
    57603,49265
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.001575Inherited
    57440,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.001575Inherited
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.001575Inherited
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.005883Inherited
    57288,57288
  • 57288 - Midkine
  • 57288 - Midkine
  • 0.01083Inherited
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0.005883Inherited
    100895,48726
  • 100895 - Kazal-type serine protease inhibitors
  • 48726 - Immunoglobulin
  • 0.005883Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.09291Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.003083Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.004721Inherited
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.02725Inherited
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.03579Inherited
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.2097Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.1314Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.6727Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.2755Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.1844Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.1861Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1029Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.1497Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.02214Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9411Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.8794Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.001662Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.5063Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.002306Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.006334Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01056Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.002646Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.06972Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002078Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.03992Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.8656Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.001266Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.05005Inherited
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.004695Inherited
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.02214Inherited
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.02785Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.06972Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.002038Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.03444Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.03579Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.001068Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.001068Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.1181Inherited
    57610,47473
  • 57610 - Thyroglobulin type-1 domain
  • 47473 - EF-hand
  • 0.001068Inherited
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.008367Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.2158Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1363Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.16Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.04955Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.06116Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.4378Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.7743Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.3392Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.0159Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.003436Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.5892Inherited
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0954Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.1904Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.002434Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.1855Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000001429Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000001429Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.00000003107Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000000463Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0000001031Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.000000577Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0000008205Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000851Direct
    81271,55186,55681
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.000001072Direct
    55186,55681,52954
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.000004088Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00001812Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.00002805Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00003424Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00003625Direct
    54928,54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.00003625Direct
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.00004005Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00005788Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.00005871Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00007348Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00007348Direct
    57196,100895,47473
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.00007802Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0001518Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0001518Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.000229Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.000293Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0003305Direct
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0005399Direct
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.0006111Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.0006111Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0008571Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0008631Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.02725Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.03118Inherited
    49265,57603,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.01305Inherited
    57440,57440,57603
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.001575Inherited
    57440,57603,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001575Inherited
    57603,57603,57440
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.001575Inherited
    57603,57603,49265
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.001575Inherited
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001575Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.4557Inherited
    57184,100895,48726
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 48726 - Immunoglobulin
  • 0.00163Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.003083Inherited
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.02725Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.189Inherited
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.03579Inherited
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.01305Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.02214Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2531Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.006334Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.006334Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.008615Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.004273Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0172Inherited
    57196,49854,57196
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.001888Inherited
    49854,49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.001888Inherited
    55486,49854,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.003083Inherited
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.004695Inherited
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.02214Inherited
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.02785Inherited
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.06936Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.06972Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.001068Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03963Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.06064Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.3912Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.02116Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1125Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0136Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.1855Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)