SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): tube development

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + + 3:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ + + 3:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ + 2:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
+ + 2:   single-multicellular organism process [GO:0044707] <74>(83|99) (548|635|419)
+ + 2:   single-organism developmental process [GO:0044767] <413>(85|101) (556|628|408)
+ 1:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
+ 1:   multicellular organism development [GO:0007275] <28>(76|90) (505|574|376)
0:   tube development [GO:0035295] <26>(6|8) (184|143|80)
- 1:   imaginal disc development [GO:0007444] <12>(1|1) (92|62|38)
- 1:   tube morphogenesis [GO:0035239] <12>(5|4) (145|122|74)
- 1:   digestive tract development [GO:0048565] <11>(1|1) (40|20|7)
- 1:   mesonephric tubule development [GO:0072164] <6>(1|1) (12|5|2)
- 1:   embryonic heart tube development [GO:0035050] <5>(0|1) (45|30|19)
- 1:   ureter development [GO:0072189] <5>(0|0) (3|1|0)
- 1:   collecting duct development [GO:0072044] <4>(0|0) (1|0|0)
- 1:   semicircular canal development [GO:0060872] <4>(1|0) (8|8|5)
- 1:   common bile duct development [GO:0061009] <3>(0|0) (4|3|1)
- 1:   nephric duct development [GO:0072176] <3>(0|0) (10|4|2)
- 1:   neural tube development [GO:0021915] <3>(0|0) (49|22|9)
- 1:   renal tubule development [GO:0061326] <3>(1|1) (36|16|2)
- 1:   respiratory tube development [GO:0030323] <3>(1|1) (24|10|6)
- 1:   metanephric tubule development [GO:0072170] <2>(0|0) (3|1|0)
- 1:   oviduct development [GO:0060066] <2>(1|1) (3|1|0)
- 1:   proximal convoluted tubule segment 1 development [GO:0072031] <2>(0|0) (0|0|0)
- 1:   long descending thin limb bend development [GO:0072065] <1>(0|0) (0|0|0)
- 1:   otic vesicle development [GO:0071599] <1>(0|0) (19|8|3)
- 1:   prebend segment development [GO:0072066] <1>(0|0) (0|0|0)
- 1:   proximal convoluted tubule segment 2 development [GO:0072032] <1>(0|0) (0|0|0)
- 1:   seminal vesicle epithelium development [GO:0061108] <1>(0|0) (0|0|0)
- 1:   metanephric part of ureteric bud development [GO:0035502](0|0) (0|0|0)
- 1:   paramesonephric duct development [GO:0061205](0|0) (2|1|0)
- 1:   seminiferous tubule development [GO:0072520](0|0) (1|0|0)
- 1:   ureter part of ureteric bud development [GO:0035503](0|0) (0|0|0)
- 1:   urethra epithelium development [GO:0061071](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cytokine00.0000000000008943Direct
POZ domain0.000019020.000764Direct
4-helical cytokines0.92920.06077Inherited
EF-hand0.83940.5101Inherited
HLH, helix-loop-helix DNA-binding domain0.0075620.00001759Inherited
Cysteine proteinases0.00000077010.701Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Astacin0.00047420.000001104Direct
BTB/POZ domain0.00001390.00001069Direct
Fibroblast growth factors (FGF)00.0000000000001992Direct
Forkhead DNA-binding domain0.0005650.000001093Direct
Papain-like0.00000089210.0002538Direct
Long-chain cytokines0.2130.0001613Inherited
HLH, helix-loop-helix DNA-binding domain0.0056490.00003846Inherited
Isoprenyl diphosphate synthases0.00014960.03474Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cystine-knot cytokines0Direct
DPY module0Direct
Chitinase insertion domain0Direct
Homeodomain-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0000000000001714Direct
GAS2 domain-like0.0000000000002421Direct
Cytokine0.0000000000004869Direct
HMG-box0.000000000006547Direct
beta-beta-alpha zinc fingers0.0000000002085Direct
Plakin repeat0.000000000587Direct
HR1 repeat0.000000002358Direct
Putative DNA-binding domain0.000000006825Direct
p53-like transcription factors0.0000000406Direct
DBL homology domain (DH-domain)0.0000001847Direct
beta-sandwich domain of Sec23/240.0000002645Direct
SAP domain0.0000002942Direct
SAND domain-like0.000001295Direct
SMAD MH1 domain0.000001481Direct
DNA-binding protein LAG-1 (CSL)0.000001525Direct
BRK domain-like0.000002677Direct
PAH2 domain0.000005554Direct
Eferin C-derminal domain-like0.00001142Direct
SPOC domain-like0.00001142Direct
HLH, helix-loop-helix DNA-binding domain0.00001172Direct
Kelch motif0.00001584Direct
Formin homology 2 domain (FH2 domain)0.00001596Direct
Zn-finger domain of Sec23/240.00002109Direct
SH3-domain0.0001746Direct
GTPase activation domain, GAP0.0002026Direct
Growth factor receptor domain0.0002574Direct
Hedgehog/DD-peptidase0.0002628Direct
Spermadhesin, CUB domain0.0002713Direct
AXH domain0.0002961Direct
POZ domain0.0005408Direct
Hedgehog/intein (Hint) domain0.0006797Direct
Ankyrin repeat0.0007082Direct
BAR/IMD domain-like0.0007441Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.0008383Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0.0008482Direct
N-terminal domain of cbl (N-cbl)0.0008482Direct
Regulator of G-protein signaling, RGS0.01952Inherited
Second domain of FERM0.4497Inherited
L domain-like0.9869Inherited
lambda repressor-like DNA-binding domains0.6813Inherited
A DNA-binding domain in eukaryotic transcription factors0.2096Inherited
Cullin homology domain0.4294Inherited
Cullin repeat-like0.4583Inherited
ARM repeat0.85Inherited
TPR-like0.4878Inherited
Immunoglobulin1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
ALDH-like0.3515Inherited
SAM/Pointed domain0.8337Inherited
Cysteine-rich domain0.008605Inherited
CCHHC domain0.01826Inherited
ThrRS/AlaRS common domain0.003128Inherited
V-type ATP synthase subunit C0.00156Inherited
EGF/Laminin0.003638Inherited
EF-hand0.4344Inherited
Spectrin repeat0.3725Inherited
IP3 receptor type 1 binding core, domain 20.03761Inherited
N-terminal coiled coil domain from apc0.003092Inherited
Tumor suppressor gene product Apc0.003092Inherited
Snake toxin-like0.1887Inherited
SRF-like0.3879Inherited
Midkine0.002117Inherited
TGS-like0.012Inherited
Troponin coil-coiled subunits0.1171Inherited
Fibrinogen C-terminal domain-like0.9362Inherited
4-helical cytokines0.04741Inherited
Calponin-homology domain, CH-domain0.8353Inherited
Frizzled cysteine-rich domain0.001208Inherited
SMAD/FHA domain0.0157Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0689Inherited
KRAB domain (Kruppel-associated box)1Inherited
Protein kinase-like (PK-like)0.03817Inherited
Leucine zipper domain0.6712Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
PP2C-like0.1452Inherited
TRAF domain-like0.3199Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
Calcium-dependent phosphotriesterase0.3391Inherited
C-type lectin-like0.6478Inherited
Cyclin-like0.9868Inherited
WD40 repeat-like0.4909Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
alpha/beta-Hydrolases1Inherited
Complement control module/SCR domain1Inherited
G protein-binding domain0.001932Inherited
Helical domain of Sec23/240.002966Inherited
C-terminal, gelsolin-like domain of Sec23/240.01824Inherited
Heparin-binding domain from vascular endothelial growth factor0.001906Inherited
FnI-like domain0.001367Inherited
Mitochondrial carrier1Inherited
E set domains0.01672Inherited
C-terminal domain of adenylylcyclase associated protein0.01167Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.05654Inherited
KA1-like0.2083Inherited
A middle domain of Talin 10.00687Inherited
alpha-catenin/vinculin-like0.5151Inherited
I/LWEQ domain0.03366Inherited
Chromo domain-like0.526Inherited
Quinoprotein alcohol dehydrogenase-like0.4709Inherited
FYVE/PHD zinc finger1Inherited
cAMP-binding domain-like1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Sec7 domain0.343Inherited
Moesin tail domain0.02683Inherited
Connexin430.00687Inherited
MIR domain0.1492Inherited
Thyroglobulin type-1 domain0.1713Inherited
Kazal-type serine protease inhibitors0.1391Inherited
Serine protease inhibitors0.002957Inherited
HAD-like0.3143Inherited
Cysteine proteinases0.6098Inherited
Triple coiled coil domain of C-type lectins0.03366Inherited
PGBD-like0.0407Inherited
Hemopexin-like domain0.05829Inherited
(Trans)glycosidases0.3266Inherited
PR-1-like0.4842Inherited
SRCR-like0.6884Inherited
Metalloproteases ("zincins"), catalytic domain0.1487Inherited
Orange domain-like0.02865Inherited
Mib/herc2 domain-like0.003092Inherited
NHL repeat0.02167Inherited
B-box zinc-binding domain0.4031Inherited
Nuclear receptor ligand-binding domain0.01585Inherited
Arginase/deacetylase0.07341Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.01392Inherited
Calcium ATPase, transmembrane domain M0.02432Inherited
Calcium ATPase, transduction domain A0.03698Inherited
Tropomyosin1Inherited
Myosin rod fragments0.6808Inherited
Eukaryotic type KH-domain (KH-domain type I)0.05206Inherited
FKBP-like0.2735Inherited
WW domain0.195Inherited
RNA-binding domain, RBD0.3263Inherited
Ras GEF0.9741Inherited
Concanavalin A-like lectins/glucanases1Inherited
Bet v1-like0.6162Inherited
Integrin domains0.9691Inherited
Cytochrome P4501Inherited
Integrin alpha N-terminal domain1Inherited
BRCT domain0.1555Inherited
PYP-like sensor domain (PAS domain)0.101Inherited
PH domain-like0.244Inherited
Bromodomain1Inherited
SOCS box-like0.1982Inherited
SH2 domain0.8034Inherited
Nucleotide cyclase1Inherited
DNA-glycosylase0.09916Inherited
TATA-box binding protein-like0.2915Inherited
Family A G protein-coupled receptor-like1Inherited
Protease propeptides/inhibitors0.8858Inherited
Galactose-binding domain-like0.9423Inherited
Fibronectin type III1Inherited
Kringle-like0.9398Inherited
NTF2-like0.4388Inherited
Subtilisin-like0.9741Inherited
Voltage-gated potassium channels0.3472Inherited
Dihydrofolate reductase-like0.05581Inherited
Glycerol-3-phosphate (1)-acyltransferase0.4517Inherited
DNA-binding domain0.9183Inherited
Notch domain0.03189Inherited
SET domain0.9611Inherited
LDL receptor-like module1Inherited
Clavaminate synthase-like1Inherited
"Winged helix" DNA-binding domain0.002636Inherited
Ubiquitin-like0.2861Inherited
Plexin repeat0.4343Inherited
Sema domain0.6442Inherited
Cadherin-like0.05457Inherited
CAD & PB1 domains0.3091Inherited
PDZ domain-like0.1523Inherited
vWA-like0.6383Inherited
TIMP-like0.1287Inherited
HIT/MYND zinc finger-like0.59Inherited
Aminoacid dehydrogenase-like, N-terminal domain0.5782Inherited
DEATH domain0.9085Inherited
Nucleotide-diphospho-sugar transferases0.9931Inherited
Acid proteases0.84Inherited
Class II aaRS ABD-related0.202Inherited
TSP-1 type 1 repeat0.6132Inherited
Class II aaRS and biotin synthetases0.6603Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    57184,90148
  • 57184 - Growth factor receptor domain
  • 90148 - DPY module
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    81995,54236
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 0Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000000000000001898Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.00000000000006572Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0.00000000000186Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.000000002441Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.000000002462Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001024Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.0000001047Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0000007483Direct
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.000001525Direct
    51905,47576
  • 51905 - FAD/NAD(P)-binding domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0.000002967Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.000002967Direct
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.000007753Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.000008272Direct
    55486,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00001142Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00001157Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0.00001852Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0.00001918Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.00002109Direct
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.00002358Direct
    55186,55681
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.00006702Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00008153Direct
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.00009973Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.0001298Direct
    54534,47473
  • 54534 - FKBP-like
  • 47473 - EF-hand
  • 0.0001489Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.0001852Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0.0002044Direct
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.0002052Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0002115Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.0002259Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0004155Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.0004155Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0004545Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0005461Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.0005738Direct
    54277,50156
  • 54277 - CAD & PB1 domains
  • 50156 - PDZ domain-like
  • 0.0005789Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0007783Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.0007783Direct
    48592,52029
  • 48592 - GroEL equatorial domain-like
  • 52029 - GroEL apical domain-like
  • 0.0007783Direct
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0008383Direct
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0.0008383Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.0008482Direct
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.3577Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.2201Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.1674Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.2335Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.6973Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9259Inherited
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.01826Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01035Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.6163Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.2668Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.6507Inherited
    81324,47473
  • 81324 - Voltage-gated potassium channels
  • 47473 - EF-hand
  • 0.003092Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.003092Inherited
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00365Inherited
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.002117Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.1492Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.3013Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.01826Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.02683Inherited
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.1194Inherited
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.03366Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.4664Inherited
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.1034Inherited
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.1253Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.2609Inherited
    48350,54236
  • 48350 - GTPase activation domain, GAP
  • 54236 - Ubiquitin-like
  • 0.003092Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.2335Inherited
    49265,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 0.066Inherited
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.02542Inherited
    57603,49265
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.01281Inherited
    57440,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.01281Inherited
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.01281Inherited
    57288,57288
  • 57288 - Midkine
  • 57288 - Midkine
  • 0.006174Inherited
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0.02542Inherited
    100895,48726
  • 100895 - Kazal-type serine protease inhibitors
  • 48726 - Immunoglobulin
  • 0.02542Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.2874Inherited
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.5142Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6884Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.3671Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.03366Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.02922Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.343Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.008564Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.001667Inherited
    57610,47473
  • 57610 - Thyroglobulin type-1 domain
  • 47473 - EF-hand
  • 0.00687Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.02861Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.8505Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.002193Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.004231Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001419Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.002966Inherited
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.001039Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.01268Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.00687Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.01167Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.4583Inherited
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0.02542Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.02257Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.04371Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1268Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.3298Inherited
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.03366Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.03579Inherited
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.175Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.02865Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.008219Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.01392Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.03804Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.2178Inherited
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.05547Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 1Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.9247Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.9566Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.008688Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.01021Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.07716Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.4999Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.1194Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.4866Inherited
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.01167Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.3057Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.8214Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.8742Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.04668Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2975Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.002117Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.01689Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.03842Inherited
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.2977Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.4667Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.02332Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.2303Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,54236,50729
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000000007352Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.00000000000079Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001024Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001024Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.000007446Direct
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.000007753Direct
    81271,55186,55681
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.00001852Direct
    57196,100895,47473
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.00001918Direct
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.00001954Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00004617Direct
    55186,55681,52954
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.00006702Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00008153Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00008153Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0001227Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0002259Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0003721Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.0004155Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.000523Direct
    54928,54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0005738Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0007783Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0007783Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0009231Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0009824Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.001906Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.1009Inherited
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.005428Inherited
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00365Inherited
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.001423Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.3945Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.01826Inherited
    57196,49854,57196
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.01167Inherited
    49854,49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.01167Inherited
    55486,49854,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.01826Inherited
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.03366Inherited
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.1034Inherited
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.1253Inherited
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.2219Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.2609Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.1009Inherited
    49265,57603,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.066Inherited
    57440,57440,57603
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.01281Inherited
    57440,57603,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.01281Inherited
    57603,57603,57440
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.01281Inherited
    57603,57603,49265
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.01281Inherited
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01281Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.8487Inherited
    57184,100895,48726
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 48726 - Immunoglobulin
  • 0.007612Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.4782Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.03366Inherited
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.066Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.3147Inherited
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.05068Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.8848Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.5834Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001485Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.004089Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001039Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001419Inherited
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.005428Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.01054Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00687Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1585Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.04371Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.04371Inherited
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.1009Inherited
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.1492Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.01392Inherited
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.04438Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.9495Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.9247Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.4876Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.04624Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2525Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2032Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.2172Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.2303Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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