SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): regulation of growth

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + 2:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ 1:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
0:   regulation of growth [GO:0040008] <11>(14|13) (139|122|67)
- 1:   regulation of developmental growth [GO:0048638] <28>(4|4) (100|100|60)
- 1:   regulation of cell growth [GO:0001558] <12>(6|7) (63|62|37)
- 1:   negative regulation of growth [GO:0045926] <6>(6|6) (57|37|17)
- 1:   positive regulation of growth [GO:0045927] <6>(6|4) (68|60|38)
- 1:   modulation of growth of symbiont involved in interaction with host [GO:0044144] <3>(0|0) (2|0|0)
- 1:   regulation of filamentous growth [GO:0010570] <3>(0|0) (8|1|0)
- 1:   regulation of growth of symbiont in host [GO:0044126] <2>(0|0) (2|0|0)
- 1:   regulation of growth rate [GO:0040009] <2>(1|1) (7|3|1)
- 1:   regulation of secondary growth [GO:2000603] <2>(0|0) (0|0|0)
- 1:   cell competition in a multicellular organism [GO:0035212](0|0) (4|1|0)
- 1:   regulation of budding cell apical bud growth [GO:0010568](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Carbohydrate phosphatase0.0000000046290.000007069Direct
Cell growth inhibitor/plasmid maintenance toxic component00.00000000000002937Direct
Cu,Zn superoxide dismutase-like0.000000000038640.00000002506Direct
Metallothionein00Direct
N-(deoxy)ribosyltransferase-like0.0000000000010050.000000005546Direct
Nqo5-like0.000000066310.000005281Direct
PIN domain-like00Direct
Ribbon-helix-helix0.000053780.0003051Direct
YefM-like0.00000031450.0000007051Direct
Protein kinase-like (PK-like)0.58170Inherited
Ankyrin repeat0.00030710.06268Inherited
(Trans)glycosidases0.0000000024780.003517Inherited
Lysozyme-like0.018890.177Inherited
Caspase-like0.0002090.04495Inherited


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bee venom hyaluronidase00Direct
Cu,Zn superoxide dismutase-like0.000000000020160.0000000742Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0.0000000042940.00001006Direct
Kid/PemK00.000000000000005999Direct
Metallothionein00Direct
N-deoxyribosyltransferase0.0000000000000065870.000000000001442Direct
Nqo5-like0.000000082840.000005887Direct
PIN domain0.000000000000043220.0000000005826Direct
RPF-like00Direct
Thioesterases0.000000025490.0000009959Direct
Protein kinases, catalytic subunit0.56420.00000000000002548Inherited
Ankyrin repeat0.0001610.15Inherited
Caspase catalytic domain0.0001460.03145Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAS2 domain-like0Direct
Metallothionein0Direct
Plakin repeat0Direct
Cystine-knot cytokines0Direct
PIN domain-like0Direct
Protein kinase-like (PK-like)0Direct
Calpain large subunit, middle domain (domain III)0Direct
Spectrin repeat0Direct
Calponin-homology domain, CH-domain0.000000000000007352Direct
Cell growth inhibitor/plasmid maintenance toxic component0.00000000000001535Direct
EGF/Laminin0.00000000000002147Direct
p53 tetramerization domain0.000000000002165Direct
EF-hand0.000000000002417Direct
Connexin430.00000000003255Direct
FAT domain of focal adhesion kinase0.000000000346Direct
Zn2/Cys6 DNA-binding domain0.00000000215Direct
N-(deoxy)ribosyltransferase-like0.000000003329Direct
PH domain-like0.000000006335Direct
Cu,Zn superoxide dismutase-like0.00000001534Direct
SH3-domain0.0000000206Direct
L domain-like0.00000003674Direct
p53-like transcription factors0.00000003908Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.00000007753Direct
PP2C-like0.0000002598Direct
YefM-like0.0000004487Direct
HR1 repeat0.0000005465Direct
BRK domain-like0.0000007692Direct
A heparin-binding domain0.0000007692Direct
Spermadhesin, CUB domain0.000001146Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.000001247Direct
TIMP-like0.00000236Direct
BAR/IMD domain-like0.00000313Direct
Nqo5-like0.000003458Direct
Kelch motif0.000004169Direct
Carbohydrate phosphatase0.000004651Direct
L27 domain0.00001071Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001188Direct
CRAL/TRIO domain0.00002173Direct
Galactose-binding domain-like0.00002657Direct
SMAD MH1 domain0.00004126Direct
PDZ domain-like0.00007044Direct
Sema domain0.00007826Direct
RelE-like0.00008902Direct
Concanavalin A-like lectins/glucanases0.0001166Direct
Growth factor receptor domain0.0001172Direct
AhpD-like0.0001183Direct
Ribbon-helix-helix0.0002127Direct
Cysteine proteinases0.0002272Direct
BPTI-like0.0003212Direct
Phenylalanine zipper0.000394Direct
SRCR-like0.0005134Direct
Frataxin/Nqo15-like0.0005611Direct
Fibronectin type III0.0006187Direct
SEA domain0.0006445Direct
Plexin repeat0.0006602Direct
STAT0.0008178Direct
"Winged helix" DNA-binding domain1Inherited
SMAD/FHA domain0.005861Inherited
Frizzled cysteine-rich domain0.2789Inherited
G protein-binding domain0.001191Inherited
Cysteine-rich domain1Inherited
4-helical cytokines1Inherited
Ran binding protein zinc finger-like0.6571Inherited
Tetraspanin0.1089Inherited
beta-beta-alpha zinc fingers1Inherited
Homodimeric domain of signal transducing histidine kinase1Inherited
CheY-like1Inherited
Bromodomain0.961Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.05709Inherited
Interleukin 8-like chemokines1Inherited
Tropomyosin0.2627Inherited
DEATH domain0.477Inherited
Caspase-like0.03474Inherited
Ubiquitin-like0.5593Inherited
SAM/Pointed domain0.805Inherited
Cytokine0.7673Inherited
RNA-binding domain, RBD1Inherited
(Phosphotyrosine protein) phosphatases II0.1882Inherited
Second domain of FERM0.01573Inherited
F-box domain0.3522Inherited
Rap/Ran-GAP0.05124Inherited
GTPase activation domain, GAP0.7892Inherited
DBL homology domain (DH-domain)0.0196Inherited
FYVE/PHD zinc finger0.8142Inherited
SRF-like0.0198Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
Chromo domain-like0.3069Inherited
WW domain0.006799Inherited
beta-sandwich domain of Sec23/240.003539Inherited
vWA-like0.6222Inherited
Acetyl-CoA synthetase-like0.9855Inherited
Toll/Interleukin receptor TIR domain1Inherited
C-type lectin-like1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3037Inherited
Nucleotide cyclase0.8347Inherited
DNA-binding domain0.0086Inherited
Transcription factor STAT-4 N-domain0.001106Inherited
Tim10-like0.01181Inherited
Invertebrate chitin-binding proteins0.02053Inherited
Tudor/PWWP/MBT0.03782Inherited
SH2 domain0.2962Inherited
PR-1-like0.1497Inherited
Lysozyme-like0.143Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.7485Inherited
Calcium ATPase, transduction domain A0.8399Inherited
Calcium ATPase, transmembrane domain M0.883Inherited
HAD-like1Inherited
WD40 repeat-like0.8224Inherited
Fibrinogen C-terminal domain-like0.04098Inherited
Immunoglobulin0.005801Inherited
Kringle-like0.07102Inherited
E set domains1Inherited
TSP-1 type 1 repeat0.05997Inherited
LCCL domain0.007346Inherited
Pentapeptide repeat-like0.001738Inherited
Cystatin/monellin0.03387Inherited
RUN domain-like0.05709Inherited
(Trans)glycosidases0.002565Inherited
Lipoxigenase0.00261Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0502Inherited
Rhomboid-like0.1211Inherited
Trypsin-like serine proteases0.7388Inherited
Homeodomain-like1Inherited
RNI-like1Inherited
Ankyrin repeat0.04894Inherited
SAICAR synthase-like0.002573Inherited
Snake toxin-like0.02357Inherited
Protease propeptides/inhibitors0.3727Inherited
Subtilisin-like0.3914Inherited
Kazal-type serine protease inhibitors0.4389Inherited
ARM repeat0.5253Inherited
Cullin homology domain0.006652Inherited
Cullin repeat-like0.2405Inherited
Cadherin-like0.03245Inherited
Blood coagulation inhibitor (disintegrin)0.002111Inherited
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.00157Inherited
HIV integrase-binding domain0.01757Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    49899,54001
  • 49899 - Concanavalin A-like lectins/glucanases
  • 54001 - Cysteine proteinases
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    47473,57997
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    81383,49899
  • 81383 - F-box domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    81995,54236
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 0Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.00000000000000826Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.000000000002165Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00000000003157Direct
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.0000000001147Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.0000000001691Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000000000877Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.000000001101Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0000000106Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0.00000002098Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.00000002198Direct
    49313,49899
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000004208Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.00000004558Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.00000005738Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.00000007753Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.0000000948Direct
    69848,49785
  • 69848 - LCCL domain
  • 49785 - Galactose-binding domain-like
  • 0.0000002969Direct
    50156,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 0.0000003043Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0.0000004436Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0000007073Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.000000996Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000001635Direct
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000001693Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.000002476Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.000002815Direct
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000005401Direct
    49854,69848
  • 49854 - Spermadhesin, CUB domain
  • 69848 - LCCL domain
  • 0.00000809Direct
    81995,56112
  • 81995 - beta-sandwich domain of Sec23/24
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000809Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00002241Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00002618Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00002618Direct
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.00002619Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00003153Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.00006489Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.0001375Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0002466Direct
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.000266Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0002722Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0003373Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000412Direct
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.0004182Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.0004618Direct
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.0005001Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.0005027Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0007227Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0007492Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0008178Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.006126Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.01442Inherited
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 1Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.1226Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.1467Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1931Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    56112,47473
  • 56112 - Protein kinase-like (PK-like)
  • 47473 - EF-hand
  • 0.009227Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 1Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.2734Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00198Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.3515Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.01673Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.3479Inherited
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.1584Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003147Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.006369Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.02167Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.006126Inherited
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.00957Inherited
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.06077Inherited
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.003819Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.9517Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01442Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3189Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.001284Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0133Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.003972Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.06662Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.1625Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.1467Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3983Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.705Inherited
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.003857Inherited
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.0118Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001076Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.001106Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.7485Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.8255Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.7045Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.3282Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.003792Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.3966Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.002092Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.01263Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.001112Inherited
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.00957Inherited
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.001572Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.004222Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.0515Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.05683Inherited
    52172,46689
  • 52172 - CheY-like
  • 46689 - Homeodomain-like
  • 0.001112Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.007735Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.007476Inherited
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.05709Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.001746Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.2096Inherited
    50729,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 0.002697Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.0474Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.05192Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.07317Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.179Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.01474Inherited
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.00157Inherited
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.007067Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,54236,50729
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    50729,50156,50729
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 0Direct
    49899,54001,49758
  • 49899 - Concanavalin A-like lectins/glucanases
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    47473,47473,57997
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 9.676e-16Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00000000000422Direct
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.00000000003255Direct
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0000000001691Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000000000877Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0000000106Direct
    49313,49313,49899
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000003617Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.0000000948Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000001211Direct
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000001415Direct
    49854,69848,49785
  • 49854 - Spermadhesin, CUB domain
  • 69848 - LCCL domain
  • 49785 - Galactose-binding domain-like
  • 0.0000002969Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0000004596Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000004901Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0000007073Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000002013Direct
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.000002815Direct
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000003699Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000003992Direct
    50156,50729,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.000005401Direct
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000005401Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00002618Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.00002618Direct
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.00006243Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.00006489Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00006489Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00009925Direct
    47473,47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.0001047Direct
    57184,57603,82895
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.0001964Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.0003162Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0003843Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0005243Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0007092Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0008533Direct
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.001176Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.1323Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1323Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.1467Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.8481Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.1308Inherited
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.9541Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.01442Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.001572Inherited
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0.03543Inherited
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.003819Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0748Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01048Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01442Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02871Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.4701Inherited
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.001176Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001106Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.7485Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.006631Inherited
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.00957Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0515Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.01181Inherited
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.02666Inherited
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1117Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05192Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.07317Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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