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Biological Process (BP): regulation of protein complex assembly

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + 2:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + 2:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ 1:   regulation of cellular component biogenesis [GO:0044087] <38>(14|14) (160|130|68)
+ 1:   regulation of cellular component organization [GO:0051128] <52>(35|32) (311|310|174)
0:   regulation of protein complex assembly [GO:0043254] <31>(9|9) (78|48|25)
- 1:   negative regulation of protein complex assembly [GO:0031333] <26>(4|4) (28|12|9)
- 1:   positive regulation of protein complex assembly [GO:0031334] <23>(3|3) (32|17|7)
- 1:   regulation of protein polymerization [GO:0032271] <7>(6|7) (42|28|18)
- 1:   regulation of DNA-templated transcription, initiation [GO:2000142] <4>(0|0) (6|5|1)
- 1:   regulation of protein oligomerization [GO:0032459] <4>(1|1) (2|0|0)
- 1:   regulation of kinetochore assembly [GO:0090234] <3>(0|0) (1|0|0)
- 1:   regulation of ATG1/ULK1 kinase complex assembly [GO:1905864] <2>(0|0) (0|0|0)
- 1:   regulation of FACT complex assembly [GO:1905644] <2>(0|0) (0|0|0)
- 1:   regulation of NLRP3 inflammasome complex assembly [GO:1900225] <2>(1|0) (7|5|1)
- 1:   regulation of SNARE complex assembly [GO:0035542] <2>(1|1) (3|0|0)
- 1:   regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly [GO:1904239] <2>(0|0) (0|0|0)
- 1:   regulation of Wnt-Frizzled-LRP5/6 complex assembly [GO:1904711] <2>(0|0) (0|0|0)
- 1:   regulation of apoptosome assembly [GO:1905100] <2>(0|0) (0|0|0)
- 1:   regulation of beta-catenin-TCF complex assembly [GO:1904863] <2>(0|0) (0|0|0)
- 1:   regulation of clathrin coat assembly [GO:1905443] <2>(0|0) (1|0|0)
- 1:   regulation of eukaryotic translation initiation factor 4F complex assembly [GO:1905535] <2>(0|0) (0|0|0)
- 1:   regulation of exocyst assembly [GO:0001928] <2>(0|0) (1|0|0)
- 1:   regulation of integrin activation [GO:0033623] <2>(0|0) (3|1|0)
- 1:   regulation of mediator complex assembly [GO:2001176] <2>(0|0) (0|0|0)
- 1:   regulation of myosin II filament assembly [GO:0043520] <2>(0|0) (2|0|0)
- 1:   regulation of podosome assembly [GO:0071801] <2>(0|0) (3|3|2)
- 1:   regulation of starch utilization system complex assembly [GO:1900512] <2>(0|0) (0|0|0)
- 1:   regulation of synaptic vesicle priming [GO:0010807] <2>(0|0) (2|0|0)
- 1:   regulation of DNA recombinase mediator complex assembly [GO:1903872] <1>(0|0) (0|0|0)
- 1:   regulation of SMAD protein complex assembly [GO:0010990] <1>(0|0) (0|0|0)
- 1:   regulation of chaperone-mediated protein complex assembly [GO:0090034] <1>(0|0) (0|0|0)
- 1:   regulation of death-inducing signaling complex assembly [GO:1903072] <1>(0|0) (0|0|0)
- 1:   regulation of nodal receptor complex assembly [GO:1900123] <1>(0|0) (0|0|0)
- 1:   regulation of proteasome assembly [GO:0090364] <1>(0|0) (0|0|0)
- 1:   regulation of ripoptosome assembly involved in necroptotic process [GO:1902442] <1>(0|0) (0|0|0)
- 1:   regulation of COPII vesicle coating [GO:0003400](0|0) (5|4|3)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 21 kDa subunit ARPC30.0000000003740.000000009975Direct
Arp2/3 complex subunits0.00000000050060Direct
Bcl-2 inhibitors of programmed cell death0.000002090.000004417Direct
Profilin (actin-binding protein)0.00000026570.00000005193Direct
Sec1/munc18-like (SM) proteins0.00023670.00007211Direct
Stathmin0.000036540.00001346Direct
Subunits of heterodimeric actin filament capping protein Capz0.00000053610.0000000185Direct
DEATH domain0.000000160.01121Inherited
Actin depolymerizing proteins0.0015470Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Arp2/3 complex 21 kDa subunit ARPC30.00000000090020.00000001698Direct
Arp2/3 complex subunits0.0000000010030Direct
Bcl-2 inhibitors of programmed cell death0.0000029550.000004612Direct
Capz alpha-1 subunit0.0000000023150.000000001232Direct
Capz beta-1 subunit0.00060230.0002005Direct
Profilin (actin-binding protein)0.00000033670.00000005196Direct
Sec1/munc18-like (SM) proteins0.00025120.00006774Direct
Stathmin0.000041150.0000128Direct
Cofilin-like0.0017780.0000000009363Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cystine-knot cytokines0Direct
Actin depolymerizing proteins0Direct
Arp2/3 complex subunits0Direct
EB1 dimerisation domain-like0.000000000000001898Direct
C-terminal, gelsolin-like domain of Sec23/240.000000000007931Direct
Formin homology 2 domain (FH2 domain)0.00000000001079Direct
SH3-domain0.00000000007825Direct
BAR/IMD domain-like0.0000000002464Direct
Toll/Interleukin receptor TIR domain0.000000001006Direct
RNI-like0.000000002692Direct
Arp2/3 complex 21 kDa subunit ARPC30.000000006036Direct
HR1 repeat0.000000007849Direct
Subunits of heterodimeric actin filament capping protein Capz0.0000000113Direct
Profilin (actin-binding protein)0.00000003203Direct
Arp2/3 complex 16 kDa subunit ARPC50.00000004359Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0000001538Direct
Heparin-binding domain from vascular endothelial growth factor0.0000001713Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.000000199Direct
VHP, Villin headpiece domain0.0000003669Direct
Outer arm dynein light chain 10.000001331Direct
Bcl-2 inhibitors of programmed cell death0.000002882Direct
Stathmin0.000008932Direct
Lipoxigenase0.000008932Direct
Cap-Gly domain0.00001048Direct
AMPKBI-like0.00003093Direct
Sec1/munc18-like (SM) proteins0.00004904Direct
AraD/HMP-PK domain-like0.00006504Direct
Actin-like ATPase domain0.00009413Direct
Helical domain of Sec23/240.0001346Direct
SH2 domain0.000137Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0002855Direct
Zn-finger domain of Sec23/240.0006211Direct
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.0006465Direct
TATA-box binding protein-like0.0006465Direct
Actin-crosslinking proteins0.0006467Direct
UBC-like0.0008824Direct
Ankyrin repeat0.1568Inherited
GAF domain-like0.01395Inherited
ENTH/VHS domain0.05553Inherited
DEATH domain0.008349Inherited
B-box zinc-binding domain0.01155Inherited
L domain-like1Inherited
dsRNA-binding domain-like0.1361Inherited
HMG-box0.3039Inherited
PYP-like sensor domain (PAS domain)0.08288Inherited
RNA-binding domain, RBD1Inherited
Protein kinase-like (PK-like)1Inherited
Moesin tail domain0.0313Inherited
SAM/Pointed domain1Inherited
PH domain-like0.01213Inherited
Second domain of FERM0.04832Inherited
Ubiquitin-like0.5541Inherited
HLH, helix-loop-helix DNA-binding domain0.6071Inherited
Calponin-homology domain, CH-domain0.5076Inherited
GTPase activation domain, GAP0.04999Inherited
RING/U-box0.6664Inherited
WD40 repeat-like0.471Inherited
PDZ domain-like0.8975Inherited
"Winged helix" DNA-binding domain0.1406Inherited
Family A G protein-coupled receptor-like0.5649Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6336Inherited
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.002586Inherited
ARM repeat0.001448Inherited
Leucine zipper domain0.02925Inherited
BRCT domain0.05248Inherited
Ribosomal protein S5 domain 2-like0.01576Inherited
Cytochrome P4500.7031Inherited
FAT domain of focal adhesion kinase0.1967Inherited
NHL repeat0.1967Inherited
Sec7 domain0.005594Inherited
CRAL/TRIO domain0.05553Inherited
DBL homology domain (DH-domain)0.06056Inherited
Quinoprotein alcohol dehydrogenase-like0.2013Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.002687Inherited
Cysteine-rich domain0.09749Inherited
beta-sandwich domain of Sec23/240.005725Inherited
vWA-like0.1503Inherited
P-loop containing nucleoside triphosphate hydrolases0.8648Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54495,54211
  • 54495 - UBC-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 0.000000000000001898Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.000000000003415Direct
    48403,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 0.000000000009043Direct
    52075,52047
  • 52075 - Outer arm dynein light chain 1
  • 52047 - RNI-like
  • 0.00000000004974Direct
    69645,69645
  • 69645 - Arp2/3 complex subunits
  • 69645 - Arp2/3 complex subunits
  • 0.00000000005477Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000001292Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000001292Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.000000001381Direct
    55781,52540
  • 55781 - GAF domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000000942Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.00000002972Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.00000003203Direct
    52058,52200
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.00000003477Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.00000005848Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.0000001713Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0000001918Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.000000358Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000000537Direct
    55945,55945
  • 55945 - TATA-box binding protein-like
  • 55945 - TATA-box binding protein-like
  • 0.000001323Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0.000002137Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.000005575Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.000008932Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.00001059Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.00003252Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.0000682Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00007993Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0001346Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0001494Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0002604Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0004154Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.0004655Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.0006211Direct
    52540,46689
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46689 - Homeodomain-like
  • 0.002586Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.01265Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0.01151Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.001737Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.01578Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.01894Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.712Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.005822Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.04832Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.03359Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.4721Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.004258Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.009679Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.03833Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.08788Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    48403,74924,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.000000004334Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000000007849Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00000002972Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.00000002972Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.00000005848Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0000001847Direct
    52058,52058,52200
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0000001881Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.0000003141Direct
    50044,55550,50729
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.0000003141Direct
    55781,52540,46689
  • 55781 - GAF domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46689 - Homeodomain-like
  • 0.0000003519Direct
    50044,50044,55550
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000001494Direct
    55550,50044,55550
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000002137Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000002137Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.000005575Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00003252Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00007993Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00007993Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.0002604Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.02415Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.01302Inherited
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.006409Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.02164Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.08788Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
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