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Biological Process (BP): positive regulation of GTPase activity

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + 4:   regulation of molecular function [GO:0065009] <12>(42|40) (274|255|136)
+ + + 3:   positive regulation of molecular function [GO:0044093] <11>(21|22) (167|154|83)
+ + + 3:   regulation of catalytic activity [GO:0050790] <11>(31|29) (223|194|106)
+ + 2:   positive regulation of catalytic activity [GO:0043085] <9>(17|16) (139|121|70)
+ + 2:   regulation of hydrolase activity [GO:0051336] <24>(18|18) (150|113|52)
+ 1:   positive regulation of hydrolase activity [GO:0051345] <23>(8|8) (86|65|30)
+ 1:   regulation of GTPase activity [GO:0043087] <4>(3|1) (45|44|21)
0:   positive regulation of GTPase activity [GO:0043547] <2>(3|1) (30|28|12)
- 1:   positive regulation of guanyl-nucleotide exchange factor activity [GO:1905099] <1>(0|0) (5|2|0)
- 1:   activation of GTPase activity [GO:0090630](0|0) (1|3|1)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
C2 domain (Calcium/lipid-binding domain, CaLB)0.0000000000000076730.00004249Direct
Phosphoglycerate mutase-like0.00000000094650.00004881Direct
Regulator of G-protein signaling, RGS00.0000000000000376Direct


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Regulator of G-protein signaling, RGS00.00000000000001591Direct


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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GTPase activation domain, GAP0Direct
PH domain-like0.000000000000003737Direct
Regulator of G-protein signaling, RGS0.00000000000001973Direct
Ras GEF0.000000000001584Direct
ARM repeat0.000000000002604Direct
DBL homology domain (DH-domain)0.000000000002766Direct
VPS9 domain0.0000000002091Direct
Zn-finger domain of Sec23/240.000000003018Direct
Helical domain of Sec23/240.000000005733Direct
Rap/Ran-GAP0.00000001079Direct
BAR/IMD domain-like0.00000002571Direct
Ubiquitin-like0.00000002584Direct
C-terminal, gelsolin-like domain of Sec23/240.000000176Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.000001002Direct
beta-sandwich domain of Sec23/240.000001283Direct
SEA domain0.000002839Direct
PDZ domain-like0.000008804Direct
FF domain0.00001383Direct
SH3-domain0.0000144Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00002864Direct
Phosphoglycerate mutase-like0.00003295Direct
ArfGap/RecO-like zinc finger0.00006234Direct
BRCT domain0.00006234Direct
Interleukin 8-like chemokines0.0003936Direct
PX domain0.0004075Direct
SAM/Pointed domain0.009742Inherited
Galactose-binding domain-like0.01156Inherited
Growth factor receptor domain0.1184Inherited
Fibronectin type III0.3114Inherited
Protein kinase-like (PK-like)1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0Direct
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    50985,48065
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.000000000004978Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.00000000001412Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00000000001451Direct
    50729,48350
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.00000000001669Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.0000000002226Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.000000001301Direct
    48371,111347
  • 48371 - ARM repeat
  • 111347 - Rap/Ran-GAP
  • 0.000000001717Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.000000003018Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.000000005598Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000005733Direct
    48350,54236
  • 48350 - GTPase activation domain, GAP
  • 54236 - Ubiquitin-like
  • 0.00000001089Direct
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.00000001419Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.00000002095Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0000002556Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.0000003076Direct
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000000865Direct
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.00001383Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00002139Direct
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.00002629Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0001787Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.002345Inherited
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.008773Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.01077Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.1416Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48065,50729,82185
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    50985,48065,50729
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.00000000003127Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0000000002226Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.0000000002226Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0000000003713Direct
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0000003881Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000001419Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000004489Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.01997Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)