SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): multi-organism reproductive process

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + 2:   biological_process [GO:0008150] <24>
+ + 2:   reproduction [GO:0000003] <6>(37|41) (304|189|85)
+ 1:   multi-organism process [GO:0051704] <17>(58|54) (383|283|130)
+ 1:   reproductive process [GO:0022414] <78>(33|37) (289|181|83)
0:   multi-organism reproductive process [GO:0044703] <15>(14|15) (214|138|64)
- 1:   sexual reproduction [GO:0019953] <6>(13|15) (198|125|52)
- 1:   insemination [GO:0007320] <4>(1|1) (4|0|0)
- 1:   female pregnancy [GO:0007565] <3>(1|2) (29|20|14)
- 1:   sperm competition [GO:0046692] <3>(0|0) (3|0|0)
- 1:   mating [GO:0007618] <2>(1|1) (24|6|1)
- 1:   parturition [GO:0007567] <2>(1|1) (6|2|1)
- 1:   regulation of brood size [GO:0060378] <2>(0|0) (0|0|0)
- 1:   agglutination involved in conjugation with cellular fusion [GO:0000752](0|0) (0|0|0)
- 1:   multi-organism reproductive behavior [GO:0044705](0|0) (0|0|0)
- 1:   penetration of zona pellucida [GO:0007341](0|0) (2|0|0)
- 1:   plantlet formation on parent plant [GO:0048624](0|0) (0|0|0)
- 1:   pollen tube adhesion [GO:0009865](0|0) (0|0|0)
- 1:   pollen tube reception [GO:0010483](0|0) (0|0|0)
- 1:   rejection of pollen from other species [GO:1990109](0|0) (0|0|0)
- 1:   sporangium germination on or near host [GO:0075222](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cadherin-like0.000000000014910.00000001557Direct
Fertilization protein00Direct
Protein kinase-like (PK-like)0.00000074980.000002343Direct
Cystine-knot cytokines0.0035051Inherited
Trypsin-like serine proteases0.04041Inherited
NAD(P)-binding Rossmann-fold domains0.63411Inherited
Lysozyme-like0.87331Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.0027530.05932Inherited
Terpenoid synthases0.0030770.5683Inherited
Cu,Zn superoxide dismutase-like0.0000030530.01305Inherited
Metalloproteases ("zincins"), catalytic domain0.1140.00001181Inherited
Phospholipase D/nuclease0.000000000000019240.0398Inherited
Defensin-like0.18461Inherited
WD40 repeat-like0.064180.01997Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
AlkB-like0.00000026810.0006555Direct
Fertilization protein00Direct
Nuclease0.0000000000000022720.00000000005256Direct
Protein kinases, catalytic subunit0.0000007560.000003505Direct
Gonadodropin/Follitropin0.00012570.002929Inherited
Nucleosome core histones0.9371Inherited
Eukaryotic proteases0.045220.4304Inherited
C-type lysozyme0.3330.8095Inherited
Isoprenyl diphosphate synthases0.00089230.02694Inherited
Cu,Zn superoxide dismutase-like0.0000039620.01238Inherited
Tyrosine-dependent oxidoreductases0.70771Inherited
Astacin0.0014380.005576Inherited
Defensin0.000054910.196Inherited
G proteins0.000010930.962Inherited
WD40-repeat0.12660.1394Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tudor/PWWP/MBT0Direct
Pseudo ankyrin repeat-like0Direct
Fertilization protein0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
RNA-binding domain, RBD0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains9.676e-16Direct
Spectrin repeat0.000000000007772Direct
ACT-like0.00000000001968Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.0000000001203Direct
Chromo domain-like0.000000000154Direct
FYVE/PHD zinc finger0.0000000004014Direct
BAR/IMD domain-like0.0000000004654Direct
A heparin-binding domain0.0000000005042Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.000000001763Direct
Cadherin-like0.00000000947Direct
YWTD domain0.00000001073Direct
PDZ domain-like0.0000001041Direct
POZ domain0.0000001889Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.0000001901Direct
EGF/Laminin0.0000009909Direct
Protein kinase-like (PK-like)0.000001518Direct
ARID-like0.000001632Direct
MAST3 pre-PK domain-like0.000001795Direct
Ankyrin repeat0.000002Direct
PAZ domain0.000002489Direct
HR1 repeat0.000003368Direct
SAM/Pointed domain0.000003944Direct
Calponin-homology domain, CH-domain0.000005658Direct
Metalloproteases ("zincins"), catalytic domain0.000007823Direct
Nuclear receptor ligand-binding domain0.000013Direct
Integrin domains0.00001739Direct
SH3-domain0.00001804Direct
Tetraspanin0.00002347Direct
Phenylalanine zipper0.00004563Direct
BRK domain-like0.0000468Direct
Regulator of G-protein signaling, RGS0.00005707Direct
Nucleoplasmin-like core domain0.00006166Direct
Snake toxin-like0.00008147Direct
G protein-binding domain0.00008481Direct
PH domain-like0.0001009Direct
ABC transporter transmembrane region0.0001463Direct
Bromodomain0.0001485Direct
A middle domain of Talin 10.0002131Direct
PR-1-like0.0002152Direct
Stathmin0.0002472Direct
Insulin-like0.0004962Direct
Transcription factor STAT-4 N-domain0.0004971Direct
Colipase-like0.0005424Direct
BRCT domain0.0007299Direct
(Phosphotyrosine protein) phosphatases II0.0009301Direct
Eukaryotic type KH-domain (KH-domain type I)0.0009588Direct
Formin homology 2 domain (FH2 domain)0.0009942Direct
Ran binding protein zinc finger-like0.5769Inherited
Complement control module/SCR domain1Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.008746Inherited
Family A G protein-coupled receptor-like0.07835Inherited
Cyclin-like0.003969Inherited
Cystine-knot cytokines1Inherited
Myosin S1 fragment, N-terminal domain0.02482Inherited
Cullin repeat-like0.09486Inherited
Succinyl-CoA synthetase domains0.1213Inherited
Glutathione synthetase ATP-binding domain-like0.8972Inherited
Oxysterol-binding protein-like0.02482Inherited
Nucleoside diphosphate kinase, NDK0.234Inherited
UBC-like0.4057Inherited
Phospholipase A2, PLA20.8276Inherited
Rhomboid-like0.1041Inherited
eIF4e-like0.2453Inherited
TAZ domain0.08904Inherited
E2F-DP heterodimerization region0.006541Inherited
Activating enzymes of the ubiquitin-like proteins0.02664Inherited
Rap/Ran-GAP0.4887Inherited
P-loop containing nucleoside triphosphate hydrolases0.5929Inherited
SpoIIaa-like0.01075Inherited
Defensin-like1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.002268Inherited
Protease propeptides/inhibitors0.0978Inherited
Subtilisin-like0.1452Inherited
Cu,Zn superoxide dismutase-like0.009758Inherited
The spindle assembly checkpoint protein mad20.05073Inherited
BRCA2 helical domain0.002073Inherited
BRCA2 tower domain0.002073Inherited
Staphylococcal nuclease0.02661Inherited
NAP-like0.08904Inherited
"Winged helix" DNA-binding domain0.04286Inherited
Bet v1-like1Inherited
L domain-like1Inherited
DNase I-like0.8344Inherited
Voltage-gated potassium channels0.6005Inherited
C-type lectin-like1Inherited
HLH, helix-loop-helix DNA-binding domain0.6802Inherited
beta-beta-alpha zinc fingers0.01276Inherited
Caspase-like0.9965Inherited
Glycoside hydrolase/deacetylase0.6871Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
HIT/MYND zinc finger-like0.03066Inherited
FKBP-like0.1666Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
SMAD MH1 domain0.007642Inherited
HMG-box0.007491Inherited
RING/U-box0.8401Inherited
SMAD/FHA domain0.09783Inherited
Histone-fold1Inherited
Ribonuclease H-like0.004941Inherited
ARM repeat0.003216Inherited
t-snare proteins0.009556Inherited
PX domain0.6531Inherited
Hemopexin-like domain0.01077Inherited
PGBD-like0.0477Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Spermadhesin, CUB domain0.04938Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain1Inherited
Riboflavin synthase domain-like1Inherited
F-box domain1Inherited
RNase III domain-like0.7843Inherited
Toll/Interleukin receptor TIR domain1Inherited
p53-like transcription factors0.02243Inherited
dsRNA-binding domain-like0.006817Inherited
Crisp domain-like0.001392Inherited
GroEL apical domain-like0.007432Inherited
beta-sandwich domain of Sec23/240.01299Inherited
Kix domain of CBP (creb binding protein)0.003625Inherited
alpha/beta-Hydrolases1Inherited
PABC (PABP) domain0.01116Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.4595Inherited
EF-hand0.6325Inherited
PLC-like phosphodiesterases0.01241Inherited
C-terminal domain of PLC-beta0.2769Inherited
Lysozyme-like1Inherited
Trefoil0.009059Inherited
GroEL-intermediate domain like0.009758Inherited
GroEL equatorial domain-like0.01299Inherited
Cystatin/monellin1Inherited
Blood coagulation inhibitor (disintegrin)0.006294Inherited
Terpenoid synthases0.487Inherited
UBA-like0.5288Inherited
Nuclear receptor coactivator interlocking domain0.1663Inherited
BPTI-like0.2729Inherited
SH2 domain0.00511Inherited
HD-domain/PDEase-like1Inherited
Fibrinogen C-terminal domain-like0.8501Inherited
vWA-like1Inherited
Integrin beta tail domain0.00145Inherited
Kringle-like0.07059Inherited
Plexin repeat0.1637Inherited
Growth factor receptor domain0.3328Inherited
STAT0.001852Inherited
Frizzled cysteine-rich domain0.0978Inherited
Cytochrome P4500.9583Inherited
SRCR-like1Inherited
Leucine zipper domain1Inherited
MHC antigen-recognition domain1Inherited
4-helical cytokines1Inherited
Alpha-macroglobulin receptor domain1Inherited
Immunoglobulin0.8271Inherited
Homeodomain-like1Inherited
WD40 repeat-like0.01511Inherited
Trypsin-like serine proteases1Inherited
SAICAR synthase-like0.3382Inherited
GAS2 domain-like0.02061Inherited
KA1-like0.1384Inherited
C-terminal domain of adenylylcyclase associated protein0.1202Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.1202Inherited
Phospholipase D/nuclease0.03066Inherited
Ubiquitin-like0.01206Inherited
Kazal-type serine protease inhibitors0.03661Inherited
Heme-dependent peroxidases1Inherited
Cysteine-rich domain0.001253Inherited
L27 domain0.05628Inherited
Second domain of FERM0.202Inherited
alpha-catenin/vinculin-like0.07412Inherited
A DNA-binding domain in eukaryotic transcription factors0.04022Inherited
N-terminal domain of cbl (N-cbl)0.05734Inherited
SOCS box-like0.3035Inherited
Ypt/Rab-GAP domain of gyp1p0.008353Inherited
CRAL/TRIO domain0.05494Inherited
Actin depolymerizing proteins0.7341Inherited
TPR-like0.8311Inherited
SAP domain0.9333Inherited
PYP-like sensor domain (PAS domain)0.001888Inherited
I/LWEQ domain0.08904Inherited
Cullin homology domain0.05575Inherited
DNA topoisomerase IV, alpha subunit0.4873Inherited
Cysteine proteinases1Inherited
Multidrug efflux transporter AcrB transmembrane domain0.851Inherited
Chaperone J-domain0.7239Inherited
Nucleotide cyclase0.06302Inherited
Fibronectin type III1Inherited
Subunits of heterodimeric actin filament capping protein Capz0.02336Inherited
NAD kinase/diacylglycerol kinase-like0.3454Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.04624Inherited
TSP-1 type 1 repeat0.6651Inherited
DBL homology domain (DH-domain)0.0174Inherited
Lamin A/C globular tail domain0.003406Inherited
Polo-box domain0.1162Inherited
DNA mismatch repair protein MutL0.1384Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.9362Inherited
Ribosomal protein S5 domain 2-like1Inherited
Tubulin C-terminal domain-like1Inherited
Tubulin nucleotide-binding domain-like1Inherited
Inhibitor of apoptosis (IAP) repeat0.003963Inherited
Cysteine-rich DNA binding domain, (DM domain)0.202Inherited
lambda repressor-like DNA-binding domains1Inherited
Galactose-binding domain-like0.6589Inherited
Integrin alpha N-terminal domain0.00425Inherited
HAD-like1Inherited
CAD & PB1 domains0.5423Inherited
(Trans)glycosidases1Inherited
Transducin (alpha subunit), insertion domain0.2877Inherited
Kelch motif0.3914Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.3707Inherited
Calcium ATPase, transduction domain A0.6355Inherited
Calcium ATPase, transmembrane domain M0.7095Inherited
Acid proteases0.9006Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    47769,140860
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0.000000000000002832Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.00000000000002147Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.000000000004693Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.00000000001903Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.0000000001203Direct
    48403,140860
  • 48403 - Ankyrin repeat
  • 140860 - Pseudo ankyrin repeat-like
  • 0.0000000002751Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000000004199Direct
    55797,57546
  • 55797 - PR-1-like
  • 57546 - Crisp domain-like
  • 0.0000000009566Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.00000001492Direct
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.0000001901Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000002282Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000004585Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.000001282Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0.000001382Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000001926Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000002081Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.000006164Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.000007634Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000009831Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00002653Direct
    49899,55486
  • 49899 - Concanavalin A-like lectins/glucanases
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.00003077Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.00003429Direct
    63501,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 0.00003665Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.00004077Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.00009781Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0001032Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0001042Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.0001166Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.0001201Direct
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.0002131Direct
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.0002472Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.0002472Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0002866Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.0002899Direct
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.0003045Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0003402Direct
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.000389Direct
    57190,57190
  • 57190 - Colipase-like
  • 57190 - Colipase-like
  • 0.000393Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0004971Direct
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0.000528Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.000786Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0009276Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0009513Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.4187Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.1663Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.02506Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.3785Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.3382Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.08904Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.005961Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.06519Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.0978Inherited
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.002073Inherited
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.002073Inherited
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.002073Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.2935Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0.002315Inherited
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.002795Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.2131Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 1Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.001392Inherited
    53335,53335
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.001875Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7666Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004898Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.03066Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.01513Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.138Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.138Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.07623Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.9231Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.9231Inherited
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.01716Inherited
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002073Inherited
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0.005961Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.005961Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.001293Inherited
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.05734Inherited
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0.005961Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.08101Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.009758Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.01735Inherited
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.05573Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.004919Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.6303Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.03502Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.003625Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.005712Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.08263Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001852Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001852Inherited
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.00534Inherited
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.05573Inherited
    81296,48239
  • 81296 - E set domains
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 0.3908Inherited
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.8555Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.6649Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1088Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.01724Inherited
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.01716Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00147Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.2399Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.04676Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.7468Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.9164Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.05737Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.05734Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.05734Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.1202Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1399Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.06044Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.1202Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.1561Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.01716Inherited
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.01716Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.1495Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.004946Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.004946Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.05573Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 1Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.07623Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.02292Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1904Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.6333Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.002315Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.009268Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.001023Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.02336Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.09811Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 1Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2839Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.4719Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.5692Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    48403,47769,140860
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.0000000007125Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000008429Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000002282Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000002282Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.000001382Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000001926Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000007101Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000007634Direct
    63501,57424,57424
  • 63501 - Frizzled cysteine-rich domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00003665Direct
    57424,57424,56487
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0.00003665Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00006869Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.00007622Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.00009781Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0001201Direct
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0002131Direct
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0003045Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000389Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0004971Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0009513Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1385Inherited
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.01716Inherited
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.002073Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.08904Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.001593Inherited
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.002073Inherited
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.002073Inherited
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.002073Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.2935Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002293Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004898Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1039Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.138Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3908Inherited
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002073Inherited
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.005961Inherited
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.05734Inherited
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.005961Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.3701Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.1632Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.01735Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.02506Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.01077Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.02253Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.1344Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001852Inherited
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.00534Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.01133Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.01924Inherited
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0.05573Inherited
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.05573Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.06461Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.2729Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.9513Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.05734Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.05734Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01716Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.004946Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.05109Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.4311Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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