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Biological Process (BP): negative regulation of growth

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + 2:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ 1:   negative regulation of biological process [GO:0048519] <52>(72|76) (445|449|253)
+ 1:   regulation of growth [GO:0040008] <11>(14|13) (139|122|67)
0:   negative regulation of growth [GO:0045926] <6>(6|6) (57|37|17)
- 1:   negative regulation of developmental growth [GO:0048640] <21>(1|1) (39|30|16)
- 1:   negative regulation of cell growth [GO:0030308] <11>(4|5) (32|22|15)
- 1:   negative regulation of growth of symbiont involved in interaction with host [GO:0044146] <2>(0|0) (2|0|0)
- 1:   negative regulation of filamentous growth [GO:0060258] <1>(0|0) (3|0|0)
- 1:   negative regulation of growth rate [GO:0045967](0|0) (0|0|0)
- 1:   negative regulation of secondary growth [GO:2000604](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
(Trans)glycosidases0.000000000000070030.000000000001305Direct
Carbohydrate phosphatase0.0000000000022240.0000000003123Direct
Cell growth inhibitor/plasmid maintenance toxic component0.00000029390.00000004542Direct
Metallothionein00Direct
Nqo5-like0.0000000012730.00000001068Direct
PIN domain-like0.00000000000022640.00000000001204Direct


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bee venom hyaluronidase00Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0.0000000000021760.0000000005102Direct
Kid/PemK0.00000019650.00000004517Direct
Metallothionein00Direct
Nqo5-like0.0000000016460.00000001255Direct
Thioesterases0.000000000083180.00000000194Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Metallothionein0Direct
Cystine-knot cytokines0Direct
p53 tetramerization domain9.676e-16Direct
Connexin430.00000000000001622Direct
HR1 repeat0.0000000000001836Direct
(Trans)glycosidases0.0000000000007148Direct
PIN domain-like0.000000000006782Direct
Carbohydrate phosphatase0.0000000001808Direct
Nqo5-like0.000000006461Direct
BAR/IMD domain-like0.00000002465Direct
Cell growth inhibitor/plasmid maintenance toxic component0.00000002795Direct
p53-like transcription factors0.00000007003Direct
FAT domain of focal adhesion kinase0.0000001354Direct
Concanavalin A-like lectins/glucanases0.0000008308Direct
AhpD-like0.000002367Direct
Fibronectin type III0.000004215Direct
Sema domain0.000008168Direct
Pentapeptide repeat-like0.00001172Direct
Plexin repeat0.0000256Direct
GAS2 domain-like0.00006174Direct
Fibrinogen C-terminal domain-like0.0001425Direct
Galactose-binding domain-like0.0001828Direct
CRAL/TRIO domain0.000186Direct
SH3-domain0.0002144Direct
LCCL domain0.0002534Direct
F-box domain0.0004324Direct
Second domain of FERM0.0006845Direct
RelE-like0.0008387Direct
"Winged helix" DNA-binding domain0.9321Inherited
SMAD/FHA domain0.2633Inherited
Frizzled cysteine-rich domain0.02402Inherited
TIMP-like0.02818Inherited
Zn2/Cys6 DNA-binding domain0.007022Inherited
TSP-1 type 1 repeat0.05187Inherited
Protein kinase-like (PK-like)0.5212Inherited
Immunoglobulin0.07897Inherited
SAM/Pointed domain0.2652Inherited
Cytokine0.4022Inherited
(Phosphotyrosine protein) phosphatases II0.09784Inherited
Rap/Ran-GAP0.001733Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4892Inherited
WW domain0.01594Inherited
GTPase activation domain, GAP0.02186Inherited
RNA-binding domain, RBD0.6824Inherited
Acetyl-CoA synthetase-like0.2535Inherited
vWA-like0.5499Inherited
ARM repeat1Inherited
Toll/Interleukin receptor TIR domain0.1331Inherited
C-type lectin-like0.2016Inherited
PR-1-like0.005019Inherited
Multidrug efflux transporter AcrB transmembrane domain0.0548Inherited
Nucleotide cyclase0.2119Inherited
L domain-like0.04789Inherited
Kringle-like0.05208Inherited
Growth factor receptor domain0.07845Inherited
E set domains0.9414Inherited
Cystatin/monellin0.00123Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81383,49899
  • 81383 - F-box domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 9.676e-16Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0.000000003573Direct
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.00000000606Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.000000006388Direct
    69848,49785
  • 69848 - LCCL domain
  • 49785 - Galactose-binding domain-like
  • 0.000000007141Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00000001252Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000009409Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0000001494Direct
    49854,69848
  • 49854 - Spermadhesin, CUB domain
  • 69848 - LCCL domain
  • 0.0000002037Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000006744Direct
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000002497Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.000008168Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00002018Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00003256Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.0002498Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0003169Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0004011Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0004275Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0004872Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0005881Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.2059Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.001225Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.007823Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.1642Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.002052Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.02656Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.01033Inherited
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.2059Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.002255Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.2094Inherited
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.00481Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.004197Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.1751Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.007984Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.002594Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.005543Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00000000003571Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000000002315Direct
    49854,69848,49785
  • 49854 - Spermadhesin, CUB domain
  • 69848 - LCCL domain
  • 49785 - Galactose-binding domain-like
  • 0.000000007141Direct
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000003213Direct
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.00000009195Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000001195Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0000001963Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000006744Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000006744Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000009617Direct
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000002497Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00004228Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0004872Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.06728Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.001197Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.02796Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001349Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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