SUPERFAMILY 1.75 HMM library and genome assignments server

Biological Process (BP): neurotrophin TRK receptor signaling pathway

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological regulation [GO:0065007] <3>(211|238) (744|904|529)
+ + + + + + 6:   biological_process [GO:0008150] <20>
+ + + + + + 6:   cellular process [GO:0009987] <5>(385|516) (1146|1338|725)
+ + + + + 5:   regulation of biological process [GO:0050789] <31>(200|223) (697|843|494)
+ + + + + 5:   response to chemical stimulus [GO:0042221] <32>(78|80) (448|436|250)
+ + + + + 5:   response to stimulus [GO:0050896] <17>(157|177) (670|749|448)
+ + + + + 5:   signaling [GO:0023052] <2>(76|77) (391|423|254)
+ + + + + 5:   single-organism cellular process [GO:0044763] <70>(212|237) (814|951|552)
+ + + + + 5:   single-organism process [GO:0044699] <27>(245|274) (871|1053|622)
+ + + + 4:   cell communication [GO:0007154] <16>(76|81) (410|439|261)
+ + + + 4:   cellular response to chemical stimulus [GO:0070887] <24>(47|50) (312|281|153)
+ + + + 4:   cellular response to stimulus [GO:0051716] <8>(97|111) (506|536|308)
+ + + + 4:   regulation of cellular process [GO:0050794] <75>(166|188) (653|778|447)
+ + + + 4:   response to organic substance [GO:0010033] <43>(58|58) (337|305|163)
+ + + + 4:   single organism signaling [GO:0044700] <7>(71|75) (391|418|251)
+ + + 3:   cellular response to organic substance [GO:0071310] <26>(36|36) (255|227|118)
+ + + 3:   response to growth factor stimulus [GO:0070848] <8>(8|6) (77|77|50)
+ + + 3:   signal transduction [GO:0007165] <32>(53|57) (330|351|208)
+ + 2:   cell surface receptor signaling pathway [GO:0007166] <27>(33|37) (223|225|140)
+ + 2:   cellular response to growth factor stimulus [GO:0071363] <9>(8|6) (74|71|47)
+ + 2:   enzyme linked receptor protein signaling pathway [GO:0007167] <5>(11|11) (125|130|74)
+ 1:   neurotrophin signaling pathway [GO:0038179] <2>(2|2) (25|20|10)
+ 1:   transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] <19>(8|8) (89|95|56)
0:   neurotrophin TRK receptor signaling pathway [GO:0048011](0|0) (16|11|5)


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DBL homology domain (DH-domain)0Direct
Nucleotide cyclase2.165e-08Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit5.483e-07Direct
IP3 receptor type 1 binding core, domain 23.018e-06Direct
PAZ domain3.366e-06Direct
Subdomain of clathrin and coatomer appendage domain9.187e-06Direct
SH3-domain1.079e-05Direct
DEATH domain1.511e-05Direct
MIR domain3.911e-05Direct
PH domain-like7.078e-05Direct
Clathrin adaptor appendage domain7.266e-05Direct
FYVE/PHD zinc finger8.182e-05Direct
Caspase-like0.0002264Direct
Protease propeptides/inhibitors0.0005506Direct
CRAL/TRIO domain0.0008667Direct
Spectrin repeat0.0008994Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 9.163e-12Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 1.654e-07Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 1.547e-06Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 2.523e-06Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 3.29e-06Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 7.051e-06Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 8.618e-06Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.0001426Direct
    50729,48366
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.0004839Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.0004839Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 5.588e-12Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1.654e-07Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 1.249e-06Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 2.091e-06Direct
    48065,50729,48366
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.0004839Direct


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