SUPERFAMILY 1.75 HMM library and genome assignments server

Biological Process (BP): neurotrophin TRK receptor signaling pathway

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological regulation [GO:0065007] <3>(207|233) (736|899|528)
+ + + + + + 6:   biological_process [GO:0008150] <20>
+ + + + + + 6:   cellular process [GO:0009987] <5>(380|506) (1135|1323|716)
+ + + + + 5:   regulation of biological process [GO:0050789] <31>(195|217) (688|837|491)
+ + + + + 5:   response to chemical stimulus [GO:0042221] <32>(75|78) (442|428|243)
+ + + + + 5:   response to stimulus [GO:0050896] <17>(156|175) (664|733|441)
+ + + + + 5:   signaling [GO:0023052] <2>(76|77) (391|425|256)
+ + + + + 5:   single-organism cellular process [GO:0044763] <70>(213|238) (801|934|545)
+ + + + + 5:   single-organism process [GO:0044699] <27>(245|275) (858|1038|615)
+ + + + 4:   cell communication [GO:0007154] <16>(76|82) (411|438|262)
+ + + + 4:   cellular response to chemical stimulus [GO:0070887] <24>(46|49) (308|270|144)
+ + + + 4:   cellular response to stimulus [GO:0051716] <8>(99|111) (501|523|302)
+ + + + 4:   regulation of cellular process [GO:0050794] <75>(161|182) (648|772|444)
+ + + + 4:   response to organic substance [GO:0010033] <43>(55|56) (330|297|158)
+ + + + 4:   single organism signaling [GO:0044700] <7>(71|76) (391|419|253)
+ + + 3:   cellular response to organic substance [GO:0071310] <26>(34|34) (248|218|113)
+ + + 3:   response to growth factor stimulus [GO:0070848] <8>(7|5) (76|76|49)
+ + + 3:   signal transduction [GO:0007165] <32>(53|57) (329|350|208)
+ + 2:   cell surface receptor signaling pathway [GO:0007166] <27>(32|35) (223|225|140)
+ + 2:   cellular response to growth factor stimulus [GO:0071363] <9>(7|5) (73|69|46)
+ + 2:   enzyme linked receptor protein signaling pathway [GO:0007167] <5>(11|11) (125|130|74)
+ 1:   neurotrophin signaling pathway [GO:0038179] <2>(1|1) (24|20|10)
+ 1:   transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] <19>(8|8) (89|95|56)
0:   neurotrophin TRK receptor signaling pathway [GO:0048011](0|0) (16|11|5)


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DBL homology domain (DH-domain)0Direct
Nucleotide cyclase1.902e-08Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit5.288e-07Direct
IP3 receptor type 1 binding core, domain 22.928e-06Direct
PAZ domain3.106e-06Direct
Subdomain of clathrin and coatomer appendage domain1.011e-05Direct
SH3-domain1.377e-05Direct
DEATH domain1.432e-05Direct
MIR domain3.64e-05Direct
PH domain-like3.955e-05Direct
FYVE/PHD zinc finger8.092e-05Direct
Clathrin adaptor appendage domain8.385e-05Direct
Caspase-like0.0002199Direct
Protease propeptides/inhibitors0.0005669Direct
CRAL/TRIO domain0.0008713Direct
Spectrin repeat0.0008892Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 8.686e-12Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 1.606e-07Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 1.502e-06Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 2.449e-06Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 3.192e-06Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 7.324e-06Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 9.498e-06Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.0001511Direct
    50729,48366
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.000509Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.000509Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 5.301e-12Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1.606e-07Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 1.212e-06Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 2.231e-06Direct
    48065,50729,48366
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.000509Direct


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