SUPERFAMILY 1.75 HMM library and genome assignments server

Biological Process (BP): neurotrophin TRK receptor signaling pathway

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological regulation [GO:0065007] <3>(208|234) (739|901|526)
+ + + + + + 6:   biological_process [GO:0008150] <20>
+ + + + + + 6:   cellular process [GO:0009987] <5>(385|515) (1146|1338|724)
+ + + + + 5:   regulation of biological process [GO:0050789] <31>(196|218) (691|840|491)
+ + + + + 5:   response to chemical stimulus [GO:0042221] <32>(77|79) (448|434|246)
+ + + + + 5:   response to stimulus [GO:0050896] <17>(155|175) (670|748|446)
+ + + + + 5:   signaling [GO:0023052] <2>(76|77) (390|423|254)
+ + + + + 5:   single-organism cellular process [GO:0044763] <70>(212|237) (815|951|551)
+ + + + + 5:   single-organism process [GO:0044699] <27>(244|273) (870|1053|621)
+ + + + 4:   cell communication [GO:0007154] <16>(76|81) (411|439|261)
+ + + + 4:   cellular response to chemical stimulus [GO:0070887] <24>(46|49) (311|276|148)
+ + + + 4:   cellular response to stimulus [GO:0051716] <8>(96|110) (508|536|308)
+ + + + 4:   regulation of cellular process [GO:0050794] <75>(163|184) (650|775|444)
+ + + + 4:   response to organic substance [GO:0010033] <43>(56|56) (336|303|162)
+ + + + 4:   single organism signaling [GO:0044700] <7>(71|75) (390|418|251)
+ + + 3:   cellular response to organic substance [GO:0071310] <26>(35|35) (254|225|117)
+ + + 3:   response to growth factor stimulus [GO:0070848] <8>(8|6) (77|77|50)
+ + + 3:   signal transduction [GO:0007165] <32>(53|57) (329|351|208)
+ + 2:   cell surface receptor signaling pathway [GO:0007166] <27>(33|36) (223|225|140)
+ + 2:   cellular response to growth factor stimulus [GO:0071363] <9>(8|6) (74|71|47)
+ + 2:   enzyme linked receptor protein signaling pathway [GO:0007167] <5>(11|11) (125|130|74)
+ 1:   neurotrophin signaling pathway [GO:0038179] <2>(2|2) (25|20|10)
+ 1:   transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] <19>(8|8) (89|95|56)
0:   neurotrophin TRK receptor signaling pathway [GO:0048011](0|0) (16|11|5)


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DBL homology domain (DH-domain)0Direct
Nucleotide cyclase2.192e-08Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit5.514e-07Direct
IP3 receptor type 1 binding core, domain 23.029e-06Direct
PAZ domain3.238e-06Direct
Subdomain of clathrin and coatomer appendage domain9.222e-06Direct
SH3-domain1.162e-05Direct
DEATH domain1.526e-05Direct
PH domain-like3.201e-05Direct
MIR domain3.763e-05Direct
Clathrin adaptor appendage domain7.297e-05Direct
FYVE/PHD zinc finger8.077e-05Direct
Caspase-like0.0002274Direct
Protease propeptides/inhibitors0.000553Direct
CRAL/TRIO domain0.0008702Direct
Spectrin repeat0.0009044Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 9.226e-12Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 1.66e-07Direct
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 1.552e-06Direct
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 2.532e-06Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 3.302e-06Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 7.079e-06Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 8.648e-06Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.0001433Direct
    50729,48366
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.0004909Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.0004909Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 5.631e-12Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 1.66e-07Direct
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 1.253e-06Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 2.098e-06Direct
    48065,50729,48366
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0.0004909Direct


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