SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Biological Process (BP): multicellular organismal reproductive process

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + 2:   biological_process [GO:0008150] <24>
+ + 2:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ + 2:   reproduction [GO:0000003] <6>(37|41) (304|189|85)
+ 1:   multicellular organism reproduction [GO:0032504] <3>(20|21) (213|135|54)
+ 1:   reproductive process [GO:0022414] <78>(33|37) (289|181|83)
0:   multicellular organismal reproductive process [GO:0048609] <23>(11|13) (193|127|53)
- 1:   oogenesis stage [GO:0022605] <9>(0|0) (3|0|0)
- 1:   gamete generation [GO:0007276] <8>(8|9) (161|108|44)
- 1:   reproductive behavior [GO:0019098] <6>(0|0) (29|11|3)
- 1:   insemination [GO:0007320] <4>(1|1) (4|0|0)
- 1:   ovulation cycle [GO:0042698] <3>(4|4) (20|11|8)
- 1:   seed dormancy process [GO:0010162] <3>(0|0) (1|0|0)
- 1:   sperm competition [GO:0046692] <3>(0|0) (3|0|0)
- 1:   dehiscence [GO:0009900] <2>(0|0) (1|0|0)
- 1:   maternal process involved in female pregnancy [GO:0060135] <2>(0|0) (6|2|1)
- 1:   regulation of brood size [GO:0060378] <2>(0|0) (0|0|0)
- 1:   seed maturation [GO:0010431] <2>(0|0) (6|2|1)
- 1:   ovulation [GO:0030728] <1>(1|2) (11|4|3)
- 1:   embryonic process involved in female pregnancy [GO:0060136](0|0) (0|0|0)
- 1:   fetal process involved in parturition [GO:0060138](0|0) (0|0|0)
- 1:   genital disc sexually dimorphic development [GO:0035263](0|0) (1|0|0)
- 1:   maternal process involved in parturition [GO:0060137](0|0) (2|1|1)
- 1:   mucilage extrusion from seed coat [GO:0080001](0|0) (1|0|0)
- 1:   penetration of zona pellucida [GO:0007341](0|0) (2|0|0)
- 1:   penile erection [GO:0043084](0|0) (0|0|0)
- 1:   plantlet formation on parent plant [GO:0048624](0|0) (0|0|0)
- 1:   seed dehydration [GO:1990068](0|0) (0|0|0)
- 1:   seminal clot liquefaction [GO:0070684](0|0) (0|0|0)
- 1:   sperm ejaculation [GO:0042713](0|0) (1|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Cadherin-like0.0000000000024180.000004404Direct
Defensin-like00.000000001578Direct
NAD(P)-binding Rossmann-fold domains0.32451Inherited
Cu,Zn superoxide dismutase-like0.00021090.03097Inherited
Cystine-knot cytokines0.00043090.003626Inherited
Bcl-2 inhibitors of programmed cell death0.10220.8535Inherited
NagB/RpiA/CoA transferase-like0.072350.02095Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.0017930.03385Inherited
Terpenoid synthases0.00070650.4123Inherited
Trypsin-like serine proteases10.8613Inherited
Phospholipase D/nuclease0.0000000000000016250.03087Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Armadillo repeat0.0000000012450.0002433Direct
Defensin00.0000000000004811Direct
IF2B-like0.0000089150.0000006788Direct
Nuclease00.00000000001932Direct
Nucleosome core histones0.033350.1525Inherited
Tyrosine-dependent oxidoreductases0.41061Inherited
Gonadodropin/Follitropin0.00009020.002142Inherited
Cu,Zn superoxide dismutase-like0.0001940.02994Inherited
Bcl-2 inhibitors of programmed cell death0.09560.8172Inherited
Isoprenyl diphosphate synthases0.00018990.02909Inherited
Eukaryotic proteases10.8326Inherited
AlkB-like0.000000037190.01157Inherited
G proteins0.78731Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Pseudo ankyrin repeat-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
RNA-binding domain, RBD0.000000000001228Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.00000000003191Direct
BAR/IMD domain-like0.00000000003723Direct
A heparin-binding domain0.0000000001355Direct
PDZ domain-like0.0000000002584Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.0000000004788Direct
HR1 repeat0.0000000004788Direct
Tudor/PWWP/MBT0.0000000008305Direct
Defensin-like0.0000000009315Direct
SH3-domain0.000000001207Direct
ACT-like0.000000006563Direct
Ankyrin repeat0.00000002122Direct
Stathmin0.0000001298Direct
G protein-binding domain0.0000003598Direct
PH domain-like0.0000006142Direct
Kix domain of CBP (creb binding protein)0.0000008588Direct
MAST3 pre-PK domain-like0.000001025Direct
Cadherin-like0.000002874Direct
YWTD domain0.000003275Direct
Chromo domain-like0.000005459Direct
SAM/Pointed domain0.00001682Direct
Phenylalanine zipper0.00002647Direct
(Phosphotyrosine protein) phosphatases II0.00005085Direct
Spectrin repeat0.00005519Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.00009824Direct
PAZ domain0.000116Direct
A middle domain of Talin 10.0001254Direct
beta-sandwich domain of Sec23/240.0001317Direct
dsRNA-binding domain-like0.0001389Direct
Regulator of G-protein signaling, RGS0.0001733Direct
Cysteine-rich domain0.0002957Direct
Colipase-like0.0003534Direct
Family A G protein-coupled receptor-like0.000418Direct
DBL homology domain (DH-domain)0.0004679Direct
ABC transporter transmembrane region0.0005422Direct
Eukaryotic type KH-domain (KH-domain type I)0.0007383Direct
Protein kinase-like (PK-like)0.000905Direct
POZ domain0.0009968Direct
EF-hand1Inherited
Nuclear receptor ligand-binding domain0.08023Inherited
Complement control module/SCR domain0.9213Inherited
Succinyl-CoA synthetase domains0.08402Inherited
Glutathione synthetase ATP-binding domain-like0.6415Inherited
Nucleoside diphosphate kinase, NDK0.1773Inherited
UBC-like0.262Inherited
Oxysterol-binding protein-like0.2755Inherited
Rhomboid-like0.1448Inherited
eIF4e-like0.1787Inherited
Myosin S1 fragment, N-terminal domain0.1077Inherited
TAZ domain0.2259Inherited
GAS2 domain-like0.01238Inherited
Ubiquitin-like0.02927Inherited
L27 domain0.017Inherited
Second domain of FERM0.117Inherited
Tetraspanin0.5653Inherited
N-terminal domain of cbl (N-cbl)0.1035Inherited
alpha-catenin/vinculin-like0.005525Inherited
A DNA-binding domain in eukaryotic transcription factors0.2259Inherited
I/LWEQ domain0.001573Inherited
Activating enzymes of the ubiquitin-like proteins0.008209Inherited
Rap/Ran-GAP0.05676Inherited
E2F-DP heterodimerization region0.05676Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.04311Inherited
Protease propeptides/inhibitors0.6412Inherited
Subtilisin-like0.987Inherited
Homeodomain-like1Inherited
SpoIIaa-like0.005569Inherited
Cu,Zn superoxide dismutase-like0.02372Inherited
Staphylococcal nuclease0.01839Inherited
NAP-like0.03106Inherited
BRCA2 helical domain0.03106Inherited
BRCA2 tower domain0.03106Inherited
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.2755Inherited
Crisp domain-like0.6412Inherited
The spindle assembly checkpoint protein mad20.6694Inherited
ARID-like0.006525Inherited
DNase I-like0.5199Inherited
L domain-like0.442Inherited
Voltage-gated potassium channels0.7469Inherited
Cysteine proteinases0.9865Inherited
C-type lectin-like1Inherited
PR-1-like1Inherited
Trypsin-like serine proteases0.7632Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
beta-beta-alpha zinc fingers0.2049Inherited
Caspase-like0.09894Inherited
CAD & PB1 domains1Inherited
Ribonuclease H-like0.01614Inherited
Phospholipase D/nuclease0.02364Inherited
HMG-box0.09149Inherited
HIT/MYND zinc finger-like0.1293Inherited
FKBP-like0.3154Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
DNA-binding domain1Inherited
NagB/RpiA/CoA transferase-like0.01588Inherited
Trimeric LpxA-like enzymes0.09894Inherited
Bcl-2 inhibitors of programmed cell death0.7556Inherited
Immunoglobulin0.05188Inherited
Fibronectin type III0.09583Inherited
PGBD-like0.1876Inherited
Hemopexin-like domain0.2661Inherited
Metalloproteases ("zincins"), catalytic domain0.8834Inherited
Putative DNA-binding domain0.001616Inherited
Riboflavin synthase domain-like0.9471Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.9604Inherited
Spermadhesin, CUB domain0.987Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
F-box domain1Inherited
SMAD MH1 domain0.03549Inherited
KA1-like0.2259Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
Zn-dependent exopeptidases1Inherited
P-loop containing nucleoside triphosphate hydrolases0.3506Inherited
alpha/beta-Hydrolases1Inherited
PK C-terminal domain-like0.07376Inherited
PK beta-barrel domain-like0.3499Inherited
Phosphoenolpyruvate/pyruvate domain0.8065Inherited
RmlC-like cupins1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
Pectin lyase-like0.8493Inherited
C-terminal domain of adenylylcyclase associated protein0.1035Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.1035Inherited
Nucleoplasmin-like core domain0.4671Inherited
RNase III domain-like0.6464Inherited
Insulin-like0.6725Inherited
Cyclin-like0.5386Inherited
PABC (PABP) domain0.03106Inherited
Terpenoid synthases0.347Inherited
Calponin-homology domain, CH-domain0.1979Inherited
SAICAR synthase-like1Inherited
Ran binding protein zinc finger-like0.4667Inherited
FYVE/PHD zinc finger0.002022Inherited
Nuclear receptor coactivator interlocking domain0.3299Inherited
BPTI-like0.9799Inherited
(Trans)glycosidases1Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5981Inherited
Heme-dependent peroxidases0.6662Inherited
Snake toxin-like0.002297Inherited
Kazal-type serine protease inhibitors0.5446Inherited
PYP-like sensor domain (PAS domain)0.014Inherited
SOCS box-like0.2258Inherited
Ypt/Rab-GAP domain of gyp1p0.007792Inherited
CRAL/TRIO domain0.1571Inherited
SAP domain0.3978Inherited
Actin depolymerizing proteins0.3978Inherited
TPR-like0.6922Inherited
Blood coagulation inhibitor (disintegrin)1Inherited
Toll/Interleukin receptor TIR domain0.6552Inherited
Cullin repeat-like0.3862Inherited
Cullin homology domain0.3258Inherited
ARM repeat0.3452Inherited
BRCT domain0.123Inherited
DNA topoisomerase IV, alpha subunit0.9548Inherited
Chaperone J-domain0.7804Inherited
SMAD/FHA domain0.1343Inherited
Histone-fold0.5159Inherited
Multidrug efflux transporter AcrB transmembrane domain0.8422Inherited
RING/U-box0.2703Inherited
Cysteine-rich DNA binding domain, (DM domain)0.9004Inherited
Nucleotide cyclase0.07648Inherited
Formin homology 2 domain (FH2 domain)0.2049Inherited
Subunits of heterodimeric actin filament capping protein Capz0.002646Inherited
NAD kinase/diacylglycerol kinase-like0.4014Inherited
TSP-1 type 1 repeat0.4214Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.02598Inherited
BRK domain-like0.002797Inherited
Lamin A/C globular tail domain0.002084Inherited
Inhibitor of apoptosis (IAP) repeat0.003643Inherited
WD40 repeat-like0.7177Inherited
DNA mismatch repair protein MutL0.651Inherited
Tubulin C-terminal domain-like1Inherited
Tubulin nucleotide-binding domain-like1Inherited
Polo-box domain0.6552Inherited
Bromodomain0.2609Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.8732Inherited
Ribosomal protein S5 domain 2-like1Inherited
Bet v1-like1Inherited
Phospholipase A2, PLA20.3299Inherited
"Winged helix" DNA-binding domain0.03178Inherited
lambda repressor-like DNA-binding domains0.9897Inherited
HD-domain/PDEase-like0.7083Inherited
Kelch motif0.6672Inherited
Galactose-binding domain-like1Inherited
Integrin domains0.7556Inherited
Integrin alpha N-terminal domain0.5314Inherited
Transcription factor STAT-4 N-domain0.6627Inherited
STAT0.7556Inherited
p53-like transcription factors0.7081Inherited
SH2 domain0.009195Inherited
EGF/Laminin0.003504Inherited
Cystine-knot cytokines0.002647Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    47769,140860
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.000000000000005554Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.000000000001488Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.00000000003191Direct
    48403,140860
  • 48403 - Ankyrin repeat
  • 140860 - Pseudo ankyrin repeat-like
  • 0.0000000001232Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001294Direct
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000003779Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0000005113Direct
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.0000006234Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.00000082Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0.0000008779Direct
    51161,48371
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.000002158Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.000003921Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.000003965Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.000005443Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.000006601Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.00001081Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.00001311Direct
    49562,50729
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 50729 - PH domain-like
  • 0.00004419Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.00005215Direct
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00007517Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.00007517Direct
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.0001254Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0001783Direct
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.000204Direct
    57190,57190
  • 57190 - Colipase-like
  • 57190 - Colipase-like
  • 0.0002556Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000276Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0002957Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0.0003142Direct
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0.0003142Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0004181Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0004679Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.0005331Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0005554Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0006228Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.0007187Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0008228Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.0009306Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1487Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.9548Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.7811Inherited
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.2259Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.01177Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.1035Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.1035Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.1035Inherited
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.003748Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.07989Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.4287Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.06571Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.003929Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.001531Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.05676Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.6412Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.01615Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.01016Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.01241Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.004106Inherited
    50249,81878
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.03106Inherited
    81872,50249
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 0.03106Inherited
    81878,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.03106Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.1035Inherited
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.2755Inherited
    55797,57546
  • 55797 - PR-1-like
  • 57546 - Crisp domain-like
  • 0.6412Inherited
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.05676Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.6662Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.07404Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.2016Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.5939Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.06571Inherited
    53335,53335
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.005075Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.03859Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03859Inherited
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0.05676Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.1876Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.07307Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.5314Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.005952Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.01142Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.1254Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.6412Inherited
    50800,51621
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0.0553Inherited
    51621,52935
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.06115Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.03106Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.6464Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.01566Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.7548Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.1739Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.2461Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.7811Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2987Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.06879Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.1035Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.1509Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 1Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 1Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.8843Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 1Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0962Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.02364Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.02364Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.008209Inherited
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0.009614Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.05676Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.008209Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0.7224Inherited
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.03106Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.06571Inherited
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0.001531Inherited
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.001851Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.005083Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.001531Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0769Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 1Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.1077Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.3978Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.6552Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.6627Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.7556Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.7556Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    48403,47769,140860
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 140860 - Pseudo ankyrin repeat-like
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.0000000002114Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000000001905Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001294Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000001294Direct
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000003779Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000004145Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.00000082Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0.0000008779Direct
    53448,51161,48371
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 48371 - ARM repeat
  • 0.000002158Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000003965Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000004071Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00004419Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.00005215Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0000996Direct
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0001254Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0001783Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.0006228Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.8843Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.2755Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.03682Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1108Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.1035Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.1035Inherited
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.1035Inherited
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.4671Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.004264Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001531Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.01403Inherited
    50249,81878,50249
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 0.03106Inherited
    81878,50249,50249
  • 81878 - BRCA2 tower domain
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.03106Inherited
    81872,50249,81878
  • 81872 - BRCA2 helical domain
  • 50249 - Nucleic acid-binding proteins
  • 81878 - BRCA2 tower domain
  • 0.03106Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.03106Inherited
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.1035Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03859Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9166Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.009277Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.06286Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1152Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.002352Inherited
    50800,51621,52935
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0.0553Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.01615Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.1293Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1077Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.02364Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.008209Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.008209Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.3684Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3978Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.6627Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.7556Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)