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Biological Process (BP): regulation of epithelial cell proliferation

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   biological_process [GO:0008150] <24>
+ + + + 4:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + 3:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + 2:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ 1:   regulation of cell proliferation [GO:0042127] <33>(17|22) (134|105|56)
0:   regulation of epithelial cell proliferation [GO:0050678] <15>(5|5) (49|32|15)
- 1:   positive regulation of epithelial cell proliferation [GO:0050679] <14>(4|4) (27|13|7)
- 1:   negative regulation of epithelial cell proliferation [GO:0050680] <13>(0|0) (18|15|6)
- 1:   regulation of endothelial cell proliferation [GO:0001936] <4>(2|2) (23|20|11)
- 1:   regulation of type B pancreatic cell proliferation [GO:0061469] <4>(0|0) (3|1|0)
- 1:   regulation of mammary gland epithelial cell proliferation [GO:0033599] <3>(0|0) (6|0|0)
- 1:   regulation of acinar cell proliferation [GO:1904697] <2>(0|0) (0|0|0)
- 1:   regulation of cholangiocyte proliferation [GO:1904054] <2>(0|0) (0|0|0)
- 1:   regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000794] <2>(0|0) (2|1|1)
- 1:   regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768] <2>(0|0) (1|0|0)
- 1:   regulation of granulosa cell proliferation [GO:1904195] <2>(0|0) (0|0|0)
- 1:   regulation of hepatocyte proliferation [GO:2000345] <2>(0|0) (3|2|1)
- 1:   regulation of keratinocyte proliferation [GO:0010837] <2>(1|1) (6|6|2)
- 1:   regulation of lens epithelial cell proliferation [GO:2001109] <2>(0|0) (2|0|0)
- 1:   regulation of thyroid gland epithelial cell proliferation [GO:1904441] <2>(0|0) (0|0|0)
- 1:   regulation of urothelial cell proliferation [GO:0050675] <2>(0|0) (1|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Nucleoside diphosphate kinase, NDK0.00000014220.00004225Direct
RNase A-like0.0000000000046690.00000000001308Direct
(Trans)glycosidases00.002185Inherited
C-type lectin-like0.000075890.1486Inherited
4-helical cytokines0.69181Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bee venom hyaluronidase00Direct
Nucleoside diphosphate kinase, NDK0.00000034350.00009361Direct
Ribonuclease A-like0.0000000000052640.00000000002199Direct
C-type lectin domain0.000075270.05775Inherited
Long-chain cytokines0.00000460.001162Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cystine-knot cytokines0Direct
Heparin-binding domain from vascular endothelial growth factor0Direct
RNase A-like0.000000000007385Direct
Alkaline phosphatase-like0.00000000001174Direct
F1 ATPase inhibitor, IF1, C-terminal domain0.0000000004567Direct
SRCR-like0.0000001062Direct
Snake toxin-like0.0000001898Direct
Nucleoside diphosphate kinase, NDK0.00002847Direct
CCCH zinc finger0.00004035Direct
SEA domain0.00005558Direct
BAR/IMD domain-like0.00007756Direct
TSP type-3 repeat0.0001238Direct
RGC domain-like0.0001371Direct
Serum albumin-like0.0001668Direct
HLH, helix-loop-helix DNA-binding domain0.0002508Direct
"Winged helix" DNA-binding domain1Inherited
HMG-box1Inherited
Leucine zipper domain0.4545Inherited
Nuclear receptor ligand-binding domain0.02073Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6596Inherited
Homeodomain-like1Inherited
Trypsin-like serine proteases0.2079Inherited
(Trans)glycosidases0.001578Inherited
Cytokine0.6057Inherited
GTPase activation domain, GAP0.07473Inherited
Calponin-homology domain, CH-domain0.6394Inherited
SAND domain-like0.02442Inherited
HIT/MYND zinc finger-like0.02442Inherited
FYVE/PHD zinc finger0.8876Inherited
Transglutaminase, two C-terminal domains0.001263Inherited
C-type lectin-like0.1193Inherited
Cysteine proteinases0.5826Inherited
E set domains0.6358Inherited
beta-beta-alpha zinc fingers0.7828Inherited
Protein kinase-like (PK-like)0.004541Inherited
Sema domain0.01188Inherited
Plexin repeat0.09072Inherited
Cysteine-rich domain0.01656Inherited
Immunoglobulin0.4311Inherited
(Phosphotyrosine protein) phosphatases II0.009219Inherited
Transcription factor STAT-4 N-domain0.002564Inherited
STAT0.006368Inherited
Concanavalin A-like lectins/glucanases0.01653Inherited
SH2 domain0.9669Inherited
p53-like transcription factors0.06207Inherited
Fibronectin type III0.01985Inherited
Second domain of FERM0.6377Inherited
TSP-1 type 1 repeat0.1556Inherited
4-helical cytokines0.941Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0.00000000003187Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.000000001087Direct
    82671,82671
  • 82671 - SEA domain
  • 82671 - SEA domain
  • 0.00000002098Direct
    48403,47031
  • 48403 - Ankyrin repeat
  • 47031 - Second domain of FERM
  • 0.00000002098Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000000435Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00003505Direct
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00003589Direct
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.00004155Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00004628Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.0000478Direct
    48552,48552
  • 48552 - Serum albumin-like
  • 48552 - Serum albumin-like
  • 0.0001514Direct
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0002518Direct
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002518Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002767Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.09289Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1307Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.004253Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.066Inherited
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.001263Inherited
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0.001263Inherited
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.001263Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.7006Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.1087Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.01188Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0282Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.002564Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.006368Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.006368Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.001263Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00000000003187Direct
    82671,82671,82671
  • 82671 - SEA domain
  • 82671 - SEA domain
  • 82671 - SEA domain
  • 0.00000002098Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000000435Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000000435Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00001283Direct
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.00003082Direct
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00003589Direct
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002518Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0002518Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0002751Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.107Inherited
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.001263Inherited
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.001263Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.002564Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.004791Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
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