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Biological Process (BP): negative regulation of epithelial cell proliferation

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + 4:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + 3:   negative regulation of biological process [GO:0048519] <52>(72|76) (445|449|253)
+ + + 3:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + 2:   negative regulation of cellular process [GO:0048523] <65>(61|62) (404|394|222)
+ + 2:   regulation of cell proliferation [GO:0042127] <33>(17|22) (134|105|56)
+ 1:   negative regulation of cell proliferation [GO:0008285] <29>(7|8) (64|50|23)
+ 1:   regulation of epithelial cell proliferation [GO:0050678] <15>(5|5) (49|32|15)
0:   negative regulation of epithelial cell proliferation [GO:0050680] <13>(0|0) (18|15|6)
- 1:   negative regulation of endothelial cell proliferation [GO:0001937] <2>(0|0) (11|9|4)
- 1:   negative regulation of acinar cell proliferation [GO:1904698](0|0) (0|0|0)
- 1:   negative regulation of cholangiocyte proliferation [GO:1904055](0|0) (0|0|0)
- 1:   negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795](0|0) (0|0|0)
- 1:   negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770](0|0) (1|0|0)
- 1:   negative regulation of granulosa cell proliferation [GO:1904196](0|0) (0|0|0)
- 1:   negative regulation of hepatocyte proliferation [GO:2000346](0|0) (0|1|1)
- 1:   negative regulation of keratinocyte proliferation [GO:0010839](0|0) (1|1|0)
- 1:   negative regulation of lens epithelial cell proliferation [GO:2001110](0|0) (0|0|0)
- 1:   negative regulation of mammary gland epithelial cell proliferation [GO:0033600](0|0) (0|0|0)
- 1:   negative regulation of thyroid gland epithelial cell proliferation [GO:1904442](0|0) (0|0|0)
- 1:   negative regulation of type B pancreatic cell proliferation [GO:1904691](0|0) (0|0|0)
- 1:   negative regulation of urothelial cell proliferation [GO:0050676](0|0) (0|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SRCR-like0Direct
Cystine-knot cytokines0Direct
Alkaline phosphatase-like0.0000000000000127Direct
F1 ATPase inhibitor, IF1, C-terminal domain0.000000000002119Direct
Transcription factor STAT-4 N-domain0.00000000001364Direct
STAT0.00000000001364Direct
BAR/IMD domain-like0.000000007816Direct
Trypsin-like serine proteases0.0000003348Direct
SEA domain0.0000007823Direct
Concanavalin A-like lectins/glucanases0.000001891Direct
(Phosphotyrosine protein) phosphatases II0.000004286Direct
p53-like transcription factors0.0000122Direct
Immunoglobulin0.00003404Direct
SH2 domain0.0001663Direct
Homeodomain-like0.05656Inherited
beta-beta-alpha zinc fingers1Inherited
Fibronectin type III0.001424Inherited
Second domain of FERM0.3075Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 9.676e-16Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0.0000000000001755Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000000001364Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000000001364Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00000000001364Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.0000000000954Direct
    82671,82671
  • 82671 - SEA domain
  • 82671 - SEA domain
  • 0.0000000005901Direct
    48403,47031
  • 48403 - Ankyrin repeat
  • 47031 - Second domain of FERM
  • 0.0000000005901Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000000009763Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.00001298Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.00002453Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0003601Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00245Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000000000001755Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000000001364Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000000001364Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000000000398Direct
    82671,82671,82671
  • 82671 - SEA domain
  • 82671 - SEA domain
  • 82671 - SEA domain
  • 0.0000000005901Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.003461Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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