SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Biological Process (BP): regulation of neurogenesis

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   multicellular organismal process [GO:0032501] <6>(93|111) (573|658|432)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + + 6:   cellular process [GO:0009987] <21>(372|486) (1162|1371|744)
+ + + + + + 6:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
+ + + + + + 6:   single-multicellular organism process [GO:0044707] <74>(83|99) (548|635|419)
+ + + + + + 6:   single-organism process [GO:0044699] <23>(290|375) (996|1199|711)
+ + + + + 5:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + + 5:   multicellular organism development [GO:0007275] <28>(76|90) (505|574|376)
+ + + + + 5:   single-organism cellular process [GO:0044763] <194>(233|302) (895|984|562)
+ + + + + 5:   single-organism developmental process [GO:0044767] <413>(85|101) (556|628|408)
+ + + + 4:   cellular developmental process [GO:0048869] <17>(54|55) (410|441|290)
+ + + + 4:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + + 4:   system development [GO:0048731] <30>(67|82) (479|532|350)
+ + + 3:   cell differentiation [GO:0030154] <91>(51|53) (394|430|283)
+ + + 3:   nervous system development [GO:0007399] <15>(24|26) (288|318|205)
+ + + 3:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + + 3:   regulation of developmental process [GO:0050793] <28>(34|33) (298|322|199)
+ + + 3:   regulation of multicellular organismal process [GO:0051239] <48>(40|41) (340|360|224)
+ + 2:   neurogenesis [GO:0022008] <2>(17|17) (253|274|179)
+ + 2:   regulation of cell differentiation [GO:0045595] <39>(20|19) (208|207|121)
+ + 2:   regulation of multicellular organismal development [GO:2000026] <72>(28|28) (253|276|169)
+ 1:   generation of neurons [GO:0048699] <7>(16|16) (245|262|173)
+ 1:   regulation of cell development [GO:0060284] <30>(13|10) (155|165|90)
+ 1:   regulation of nervous system development [GO:0051960] <13>(11|8) (152|178|103)
0:   regulation of neurogenesis [GO:0050767] <6>(11|8) (132|153|84)
- 1:   regulation of neuron differentiation [GO:0045664] <13>(7|5) (109|126|70)
- 1:   negative regulation of neurogenesis [GO:0050768] <7>(3|2) (64|51|32)
- 1:   positive regulation of neurogenesis [GO:0050769] <6>(3|2) (72|70|41)
- 1:   regulation of gliogenesis [GO:0014013] <6>(2|2) (44|25|13)
- 1:   regulation of neuron migration [GO:2001222] <3>(0|0) (13|4|0)
- 1:   regulation of neuroblast proliferation [GO:1902692] <2>(0|0) (6|3|2)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Formate/glycerate dehydrogenase catalytic domain-like0.000000005130.000007836Direct
Immunoglobulin0.000019630.0000000005892Direct
Metallothionein0.00000000040840.000004381Direct
Family A G protein-coupled receptor-like0.52010.02161Inherited
Stathmin0.12380.1045Inherited
Serpins0.000031730.04141Inherited
HLH, helix-loop-helix DNA-binding domain0.0074610.0000000000001618Inherited
Caspase-like0.012450.02863Inherited
Interleukin 8-like chemokines0.055850.07505Inherited
Actin depolymerizing proteins0.03730.07925Inherited
EF-hand0.096480.0004378Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Formate/glycerate dehydrogenases, substrate-binding domain0.0000000061890.000001713Direct
Metallothionein0.00000000088680.00001228Direct
Rhodopsin-like0.3070.01464Inherited
Stathmin0.10470.1037Inherited
HLH, helix-loop-helix DNA-binding domain0.0056010.000000000001043Inherited
Caspase catalytic domain0.0099120.03022Inherited
Interleukin 8-like chemokines0.046630.118Inherited
Cofilin-like0.031210.2261Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
HMG-box0.000000000000001898Direct
HLH, helix-loop-helix DNA-binding domain0.00000000000008645Direct
GAS2 domain-like0.00000000001194Direct
Immunoglobulin0.0000000003435Direct
Plakin repeat0.0000000006312Direct
Metallothionein0.000002858Direct
Kelch motif0.000003037Direct
Formate/glycerate dehydrogenase catalytic domain-like0.000005163Direct
Fibronectin type III0.00001406Direct
GTPase activation domain, GAP0.00005021Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00006813Direct
Midkine0.00008113Direct
Orange domain-like0.0001059Direct
BRCT domain0.0001339Direct
Arginase/deacetylase0.0002176Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0.0002461Direct
TIMP-like0.0002875Direct
EF-hand0.000307Direct
FF domain0.0005628Direct
Frizzled cysteine-rich domain0.9115Inherited
Quinoprotein alcohol dehydrogenase-like0.09305Inherited
Ubiquitin-like0.913Inherited
cAMP-binding domain-like0.3912Inherited
Ras GEF0.001832Inherited
PDZ domain-like0.9364Inherited
FnI-like domain0.506Inherited
MFS general substrate transporter1Inherited
SMAD/FHA domain0.9688Inherited
beta-beta-alpha zinc fingers0.07356Inherited
TSP-1 type 1 repeat1Inherited
Tropomyosin0.7192Inherited
Homeodomain-like1Inherited
NTF2-like0.7277Inherited
lambda repressor-like DNA-binding domains0.1243Inherited
beta-sandwich domain of Sec23/240.4922Inherited
Tudor/PWWP/MBT0.1025Inherited
Helical domain of Sec23/240.01634Inherited
Zn-finger domain of Sec23/240.08289Inherited
Cullin homology domain0.4851Inherited
SET domain0.5388Inherited
Eukaryotic type KH-domain (KH-domain type I)0.001041Inherited
Trypsin-like serine proteases1Inherited
TNF-like1Inherited
Cyclin-like1Inherited
Actin depolymerizing proteins0.06238Inherited
PH domain-like0.8251Inherited
alpha/beta-Hydrolases1Inherited
DBL homology domain (DH-domain)0.03279Inherited
Bromodomain1Inherited
Rap/Ran-GAP0.07846Inherited
RING/U-box0.2462Inherited
SH2 domain0.1331Inherited
p53-like transcription factors0.1242Inherited
EGF/Laminin0.2726Inherited
F-box domain0.8876Inherited
Intermediate filament protein, coiled coil region0.2086Inherited
Cysteine-rich domain0.001747Inherited
Transcription factor STAT-4 N-domain0.185Inherited
CAD & PB1 domains0.185Inherited
STAT0.185Inherited
CRAL/TRIO domain0.256Inherited
dsRNA-binding domain-like0.328Inherited
RNase III domain-like0.0193Inherited
LDL receptor-like module0.8441Inherited
YWTD domain0.02302Inherited
FAD/NAD(P)-binding domain1Inherited
Sema domain0.02846Inherited
Plexin repeat0.03911Inherited
Spermadhesin, CUB domain0.2168Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.1532Inherited
Calponin-homology domain, CH-domain0.07116Inherited
Spectrin repeat0.008343Inherited
Regulator of G-protein signaling, RGS0.04789Inherited
vWA-like0.4418Inherited
FYVE/PHD zinc finger1Inherited
Serpins0.03192Inherited
Interleukin 8-like chemokines0.05895Inherited
C-terminal, gelsolin-like domain of Sec23/240.00428Inherited
BAR/IMD domain-like1Inherited
SH3-domain1Inherited
Notch domain0.02246Inherited
Ankyrin repeat0.2165Inherited
4-helical cytokines0.09102Inherited
DEATH domain0.7762Inherited
Protein kinase-like (PK-like)0.03744Inherited
RNA-binding domain, RBD0.8785Inherited
L domain-like0.08729Inherited
Galactose-binding domain-like0.2155Inherited
SAM/Pointed domain0.5652Inherited
SOCS box-like0.001752Inherited
Caspase-like0.02187Inherited
Cadherin-like0.8176Inherited
Cytokine0.0109Inherited
ARM repeat1Inherited
NHL repeat0.09305Inherited
Carboxypeptidase regulatory domain-like0.185Inherited
TNF receptor-like0.04194Inherited
PP2C-like0.2577Inherited
TRAF domain-like0.2375Inherited
PYP-like sensor domain (PAS domain)0.4807Inherited
SRF-like0.3605Inherited
Thyroglobulin type-1 domain0.08411Inherited
Hect, E3 ligase catalytic domain0.005212Inherited
CAPPD, an extracellular domain of amyloid beta A4 protein0.01996Inherited
A heparin-binding domain0.03419Inherited
Amyloid beta a4 protein copper binding domain (domain 2)0.2238Inherited
E set domains0.5166Inherited
Family A G protein-coupled receptor-like0.01639Inherited
DHS-like NAD/FAD-binding domain0.01815Inherited
Cystine-knot cytokines0.8943Inherited
Hedgehog/intein (Hint) domain0.9359Inherited
Hedgehog/DD-peptidase0.9359Inherited
Concanavalin A-like lectins/glucanases1Inherited
Fibrinogen C-terminal domain-like0.6004Inherited
Carbonic anhydrase0.00165Inherited
Cupredoxins0.04879Inherited
Growth factor receptor domain0.8739Inherited
Kringle-like0.2802Inherited
RUN domain-like0.003006Inherited
Kazal-type serine protease inhibitors0.006352Inherited
MHC antigen-recognition domain0.01122Inherited
TAFH domain-like0.2367Inherited
(Phosphotyrosine protein) phosphatases II0.8959Inherited
FKBP-like0.0821Inherited
Composite domain of metallo-dependent hydrolases0.05125Inherited
Metallo-dependent hydrolases0.06979Inherited
Stathmin0.08289Inherited
Apolipoprotein A-I0.2702Inherited
Sialidases0.2702Inherited
G protein-binding domain0.02189Inherited
Blood coagulation inhibitor (disintegrin)0.01094Inherited
TATA-box binding protein-like0.2367Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    56491,109843
  • 56491 - A heparin-binding domain
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0Direct
    48371,52087
  • 48371 - ARM repeat
  • 52087 - CRAL/TRIO domain
  • 0Direct
    48350,48371
  • 48350 - GTPase activation domain, GAP
  • 48371 - ARM repeat
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    47473,57610
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 9.676e-16Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.000000000000003737Direct
    54495,54211
  • 54495 - UBC-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0000000000001884Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0000000000003803Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0000000000006203Direct
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.00000000001194Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.00000000001575Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.0000000004298Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000000006105Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0.0000000006548Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.0000000006548Direct
    48371,49785
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0.000000003633Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.00000001295Direct
    63748,48371
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 0.00000001966Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00000004776Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.0000001947Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0000006212Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0.0000009105Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.000001119Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.000002179Direct
    49723,140741
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 140741 - RUN domain-like
  • 0.000002436Direct
    47769,52200
  • 47769 - SAM/Pointed domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.000002436Direct
    48371,47769
  • 48371 - ARM repeat
  • 47769 - SAM/Pointed domain
  • 0.000002436Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000003914Direct
    140741,49723
  • 140741 - RUN domain-like
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.000005345Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.00001162Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.0000118Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.00001184Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.00001377Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00002721Direct
    47473,50729
  • 47473 - EF-hand
  • 50729 - PH domain-like
  • 0.00002765Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.00003071Direct
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.00004078Direct
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.00004366Direct
    57288,57288
  • 57288 - Midkine
  • 57288 - Midkine
  • 0.00006666Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00006728Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.00006924Direct
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00008397Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.00008397Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.00009564Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.0001059Direct
    47370,63748
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.00015Direct
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.0001565Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.000192Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002402Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.0002461Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0003073Direct
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0003783Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.0003834Direct
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.0004993Direct
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0005535Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0005588Direct
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.0005628Direct
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.0006707Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.02568Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2657Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.002908Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.3912Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.9697Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.7695Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.7215Inherited
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.2897Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.08411Inherited
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.08258Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 1Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.01634Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.08289Inherited
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0.1671Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.9359Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.3403Inherited
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.02568Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.01385Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1312Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.03715Inherited
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.08289Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.185Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.185Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.185Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.3299Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4828Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.01634Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.009884Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.8442Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.9576Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 1Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.7695Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.01234Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 1Inherited
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.009331Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.1057Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.001037Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.02004Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.522Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.05722Inherited
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.02568Inherited
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.02568Inherited
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.02568Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.06242Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.1671Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.4596Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.459Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.02246Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.02246Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.8816Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.1828Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.655Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 1Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.8133Inherited
    49313,49899
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.08524Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.009884Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.6934Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.9223Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.2702Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.04194Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.03715Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.185Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.0325Inherited
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.02568Inherited
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.2238Inherited
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.522Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.5442Inherited
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.596Inherited
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.9359Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.06238Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.05363Inherited
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.1671Inherited
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5235Inherited
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.2367Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.06238Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.09305Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 1Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.004245Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.001403Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.2925Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.05125Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.025Inherited
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.001223Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.004677Inherited
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0.02568Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.006072Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    48350,48371,52087
  • 48350 - GTPase activation domain, GAP
  • 48371 - ARM repeat
  • 52087 - CRAL/TRIO domain
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    63748,48371,49785
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0Direct
    100895,47473,57610
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.000000000000001898Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.00000000000002495Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00000000002969Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00000003362Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.000001119Direct
    54534,54534,48452
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.0000017Direct
    47769,47769,52200
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.000002436Direct
    48371,47769,47769
  • 48371 - ARM repeat
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.000002436Direct
    140741,49723,140741
  • 140741 - RUN domain-like
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 140741 - RUN domain-like
  • 0.000002436Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.00002091Direct
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.00002765Direct
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.00002953Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.00003071Direct
    57903,47370,63748
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.00006029Direct
    49854,57535,49854
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00008397Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00009564Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.00009564Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0001137Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0002461Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0003834Direct
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.0004416Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0005588Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0005588Direct
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0006322Direct
    57196,57196,63825
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0009121Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0009121Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2237Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.008343Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57424,57196,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001223Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.256Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2878Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03715Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.185Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4402Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.8107Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.7636Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.7695Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.7695Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7695Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.009884Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.1057Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.004477Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.001403Inherited
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.596Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.08289Inherited
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.02568Inherited
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.02568Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.01996Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.2878Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.7659Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3706Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1572Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.01078Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.02246Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.02246Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2238Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.08411Inherited
    49313,49313,49899
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.08524Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.6934Inherited
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.02568Inherited
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.522Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.6977Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 1Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.4418Inherited
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.01078Inherited
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.1671Inherited
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.1671Inherited
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.08258Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1987Inherited
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.2897Inherited
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.2367Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.06238Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.06238Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.02089Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.9987Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.001599Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)