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Biological Process (BP): regulation of catalytic activity

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + 2:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ 1:   regulation of molecular function [GO:0065009] <12>(42|40) (274|255|136)
0:   regulation of catalytic activity [GO:0050790] <11>(31|29) (223|194|106)
- 1:   regulation of hydrolase activity [GO:0051336] <24>(18|18) (150|113|52)
- 1:   regulation of transferase activity [GO:0051338] <24>(13|10) (114|100|61)
- 1:   regulation of oxidoreductase activity [GO:0051341] <18>(3|3) (12|2|0)
- 1:   negative regulation of catalytic activity [GO:0043086] <9>(11|11) (104|61|27)
- 1:   positive regulation of catalytic activity [GO:0043085] <9>(17|16) (139|121|70)
- 1:   regulation of lyase activity [GO:0051339] <8>(2|2) (16|6|2)
- 1:   regulation of ligase activity [GO:0051340] <7>(0|0) (1|0|0)
- 1:   modulation of catalytic activity in other organism involved in symbiotic interaction [GO:0052203] <5>(0|0) (3|2|1)
- 1:   regulation of cyclase activity [GO:0031279] <5>(2|2) (17|6|2)
- 1:   regulation of isomerase activity [GO:0010911] <3>(0|0) (2|0|0)
- 1:   regulation of histone demethylase activity (H3-K4 specific) [GO:1904173] <2>(0|0) (0|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bcl-2 inhibitors of programmed cell death0.00022130.00001639Direct
Cystatin/monellin0.000024950.00029Direct
Inhibitor of apoptosis (IAP) repeat0.00000000022410Direct
Insulin-like0.000091290.00001236Direct
Metallothionein0.000009720.0004774Direct
Regulator of G-protein signaling, RGS0.0000000000000016250.0000126Direct
RNase A-like00.000000000009875Direct
Serpins00.000000000001836Direct
The spindle assembly checkpoint protein mad20.00000000010530.000008336Direct
4-helical cytokines11Inherited
UDP-Glycosyltransferase/glycogen phosphorylase0.62291Inherited
Casein kinase II beta subunit0.11170.0831Inherited
L30e-like0.00029570.1746Inherited
(Phosphotyrosine protein) phosphatases II0.0010370.00004749Inherited
Caspase-like0.0000097610.002772Inherited
EF-hand0.75930.547Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.054460.9031Inherited
Class I glutamine amidotransferase-like0.22670.8337Inherited
Kazal-type serine protease inhibitors0.00050720.00699Inherited
Metallo-dependent hydrolases0.00000000000010330.02076Inherited
TIMP-like00.2671Inherited
Calcium-dependent phosphotriesterase0.088250.05011Inherited
Protein kinase-like (PK-like)0.64060.000009172Inherited
Immunoglobulin0.088250.1314Inherited
Phosphoglycerate mutase-like0.00075280.192Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000019021Inherited
Cu,Zn superoxide dismutase-like0.043290.03015Inherited
Cytokine0.000000035790.01359Inherited
P-loop containing nucleoside triphosphate hydrolases0.32121Inherited
Family A G protein-coupled receptor-like0.50550.00000000000008578Inherited
Ankyrin repeat0.67991Inherited


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Bcl-2 inhibitors of programmed cell death0.00028890.00001682Direct
Caspase catalytic domain0.000016740.0004821Direct
Dual specificity phosphatase-like0.00069650.00004932Direct
Inhibitor of apoptosis (IAP) repeat0.00000000060690Direct
Insulin-like0.00016530.00005287Direct
Long-chain cytokines0.00018150.00001541Direct
Ovomucoid domain III-like0.00021840.00000001525Direct
Regulator of G-protein signaling, RGS0.0000000000000065870.00001298Direct
Renal dipeptidase00Direct
Ribonuclease A-like0.000000000000004450.00000000007486Direct
Serpins0.0000000000000022720.00000000004746Direct
SGL-like0.00000000072120.0000001491Direct
The spindle assembly checkpoint protein mad20.00000000032370.000006484Direct
Tissue inhibitor of metalloproteinases, TIMP00.0000000000003233Direct
UDPGT-like0.03350.2878Inherited
Casein kinase II beta subunit0.11320.07799Inherited
Proteasome subunits0.045390.4307Inherited
DJ-1/PfpI0.22460.212Inherited
Cystatins0.00029630.002097Inherited
S100 proteins0.2340.2063Inherited
Papain-like0.30050.3917Inherited
Protein kinases, catalytic subunit0.66360.00006633Inherited
Cu,Zn superoxide dismutase-like0.045390.02846Inherited
Fibroblast growth factors (FGF)0.000000064170.04378Inherited
Metallothionein0.000027050.00114Inherited
Calmodulin-like0.50990.9933Inherited
Rhodopsin-like0.3370.000000000007015Inherited
G proteins0.045570.2395Inherited
Ankyrin repeat0.72921Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cystine-knot cytokines0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
F1 ATPase inhibitor, IF1, C-terminal domain0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Heparin-binding domain from vascular endothelial growth factor0Direct
Plant inhibitors of proteinases and amylases0Direct
FAT domain of focal adhesion kinase0Direct
Calpain large subunit, middle domain (domain III)0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Family A G protein-coupled receptor-like0.00000000000004552Direct
GTPase activation domain, GAP0.0000000000001447Direct
Serpins0.00000000000101Direct
RNase A-like0.00000000000555Direct
Chitinase insertion domain0.00000000002347Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.0000000002771Direct
A heparin-binding domain0.000000001154Direct
Satiety factor CART (cocaine and amphetamine regulated transcript)0.000000002005Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.000000004002Direct
PH domain-like0.00000002655Direct
N-terminal coiled coil domain from apc0.000000033Direct
Tumor suppressor gene product Apc0.000000033Direct
N-terminal domain of adenylylcyclase associated protein, CAP0.0000001715Direct
DBL homology domain (DH-domain)0.0000004316Direct
Bowman-Birk inhibitor, BBI0.00000104Direct
The spindle assembly checkpoint protein mad20.000005499Direct
Protein kinase-like (PK-like)0.000006058Direct
Insulin-like0.000008194Direct
Regulator of G-protein signaling, RGS0.000008351Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.000008893Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.00001006Direct
Smac/diablo0.00001006Direct
Nucleoplasmin-like core domain0.00001086Direct
Bcl-2 inhibitors of programmed cell death0.00001091Direct
Ras GEF0.00001424Direct
RGC domain-like0.0000165Direct
(Phosphotyrosine protein) phosphatases II0.00003206Direct
C-terminal domain of adenylylcyclase associated protein0.00004415Direct
DNA clamp0.00004663Direct
Oncogene products0.00004857Direct
cAMP-binding domain-like0.00005267Direct
Galactose-binding domain-like0.00005936Direct
Transducin (heterotrimeric G protein), gamma chain0.00006794Direct
GLA-domain0.00008624Direct
post-AAA+ oligomerization domain-like0.00008624Direct
Fibronectin type III0.0001123Direct
PP2C-like0.0001411Direct
N-terminal domain of cbl (N-cbl)0.0001725Direct
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0.0001795Direct
Cystatin/monellin0.000202Direct
Apolipoprotein A-I0.0002555Direct
Growth factor receptor domain0.0002563Direct
Sec7 domain0.0002605Direct
Metallothionein0.0003353Direct
PTPA-like0.0003799Direct
SH2 domain0.0005298Direct
RCC1/BLIP-II0.000633Direct
EGF/Laminin0.0006511Direct
SH3-domain0.0006991Direct
Colipase-like0.0007109Direct
Stathmin0.0008899Direct
Proteasome activator0.0009506Direct
Transducin (alpha subunit), insertion domain0.0009924Direct
dsRNA-binding domain-like0.03206Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
ENTH/VHS domain0.4202Inherited
GAT-like domain0.04897Inherited
Cysteine proteinases1Inherited
RING/U-box1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
DHS-like NAD/FAD-binding domain1Inherited
4-helical cytokines0.9167Inherited
Complement control module/SCR domain0.4236Inherited
Kazal-type serine protease inhibitors0.005151Inherited
Pectin lyase-like1Inherited
Kringle-like0.01776Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.9972Inherited
Leucine zipper domain1Inherited
Bet v1-like0.9631Inherited
Domain from hypothetical 2610208m17rik protein0.9348Inherited
Second domain of FERM0.2747Inherited
DNase I-like0.1591Inherited
Protein serine/threonine phosphatase 2C, C-terminal domain0.001991Inherited
HSP40/DnaJ peptide-binding domain0.3203Inherited
DnaJ/Hsp40 cysteine-rich domain0.3855Inherited
ARM repeat0.005629Inherited
LDL receptor-like module0.3648Inherited
Hairpin loop containing domain-like0.02813Inherited
Toll/Interleukin receptor TIR domain1Inherited
Frizzled cysteine-rich domain1Inherited
FYVE/PHD zinc finger0.7729Inherited
(Trans)glycosidases0.1225Inherited
Ankyrin repeat1Inherited
Prion-like1Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.4509Inherited
HIN-2000 domain-like0.3108Inherited
DNA/RNA polymerases1Inherited
WD40 repeat-like0.502Inherited
RNA-binding domain, RBD1Inherited
HSP20-like chaperones0.2485Inherited
TPR-like1Inherited
BAG domain0.006471Inherited
F-box domain1Inherited
Nucleotide cyclase0.06701Inherited
CRAL/TRIO domain0.00644Inherited
L domain-like0.1503Inherited
Chaperone J-domain0.02631Inherited
Polo-box domain0.24Inherited
UBC-like1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.8048Inherited
TRAF domain-like1Inherited
Sialidases0.01654Inherited
TB module/8-cys domain0.03284Inherited
Cytokine0.01017Inherited
TNF-like0.3911Inherited
Cu,Zn superoxide dismutase-like0.02307Inherited
Tetraspanin0.1112Inherited
Immunoglobulin0.1051Inherited
Concanavalin A-like lectins/glucanases1Inherited
Fibrinogen C-terminal domain-like0.01051Inherited
Thyroglobulin type-1 domain0.001985Inherited
TIMP-like0.2198Inherited
Troponin coil-coiled subunits0.2656Inherited
SAP domain0.2656Inherited
Metallo-dependent hydrolases0.01573Inherited
Flavoproteins0.05223Inherited
Elafin-like0.8659Inherited
Serum albumin-like0.03348Inherited
Nitric oxide (NO) synthase oxygenase domain0.003247Inherited
Oligoxyloglucan reducing end-specific cellobiohydrolase0.07352Inherited
"Winged helix" DNA-binding domain1Inherited
HMA, heavy metal-associated domain0.1705Inherited
Nucleic acid-binding proteins1Inherited
DNA repair protein MutS, domain III0.14Inherited
Protease propeptides/inhibitors0.7584Inherited
Subtilisin-like0.824Inherited
Hook domain0.07352Inherited
Interleukin 8-like chemokines0.4236Inherited
BEACH domain0.004799Inherited
beta-sandwich domain of Sec23/240.1224Inherited
PX domain0.2937Inherited
CSL zinc finger0.9348Inherited
Calcium-dependent phosphotriesterase0.03884Inherited
Tropomyosin0.9836Inherited
Cyclophilin-like0.6762Inherited
Bromodomain1Inherited
Roadblock/LC7 domain0.1241Inherited
L30e-like0.141Inherited
Caspase-like0.002011Inherited
TNF receptor-like0.4648Inherited
DEATH domain0.5371Inherited
RNI-like0.7323Inherited
Succinyl-CoA synthetase domains0.1514Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Transcription factor STAT-4 N-domain0.6274Inherited
STAT0.6274Inherited
p53-like transcription factors0.9304Inherited
FAD-binding/transporter-associated domain-like1Inherited
SAM/Pointed domain0.678Inherited
Phosphoglycerate mutase-like0.1556Inherited
Zn-finger domain of Sec23/240.002625Inherited
Helical domain of Sec23/240.004352Inherited
BAR/IMD domain-like0.01547Inherited
Rap/Ran-GAP0.01299Inherited
ArfGap/RecO-like zinc finger0.01012Inherited
FF domain0.03091Inherited
SEA domain0.03491Inherited
C-terminal, gelsolin-like domain of Sec23/240.05134Inherited
VPS9 domain0.001316Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain1Inherited
BRCT domain0.1591Inherited
RUN domain-like0.01081Inherited
NAD kinase/diacylglycerol kinase-like0.7898Inherited
Calponin-homology domain, CH-domain0.9952Inherited
Notch domain0.02184Inherited
alpha-ketoacid dehydrogenase kinase, N-terminal domain0.03896Inherited
NAD(P)-linked oxidoreductase1Inherited
Sema domain0.004799Inherited
Plexin repeat0.01632Inherited
Fic-like0.01063Inherited
E set domains1Inherited
Supernatant protein factor (SPF), C-terminal domain0.1122Inherited
Class I glutamine amidotransferase-like0.7362Inherited
N-acetylmuramoyl-L-alanine amidase-like0.1241Inherited
SIS domain0.1033Inherited
Ubiquitin-like0.006756Inherited
Nuclear receptor ligand-binding domain1Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
CAD & PB1 domains1Inherited
PAP/OAS1 substrate-binding domain0.03884Inherited
Nucleotidyltransferase0.215Inherited
Trypsin-like serine proteases1Inherited
PapD-like0.08919Inherited
Quinoprotein alcohol dehydrogenase-like0.3421Inherited
EF-hand0.4677Inherited
Periplasmic binding protein-like I0.055Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5164Inherited
Prefoldin0.2953Inherited
Cadherin-like1Inherited
vWA-like0.3096Inherited
WW domain1Inherited
PDZ domain-like0.6978Inherited
Integrin domains0.3648Inherited
Casein kinase II beta subunit0.06548Inherited
Hedgehog/intein (Hint) domain0.6337Inherited
Hedgehog/DD-peptidase0.6337Inherited
Integrin alpha N-terminal domain0.1896Inherited
SRF-like0.6844Inherited
SMAD/FHA domain0.9792Inherited
Hormone receptor domain0.008086Inherited
IP3 receptor type 1 binding core, domain 20.01165Inherited
MIR domain0.1289Inherited
PLC-like phosphodiesterases0.7611Inherited
YWTD domain0.8304Inherited
Cysteine-rich domain1Inherited
CCCH zinc finger0.003204Inherited
SOCS box-like0.01661Inherited
Tudor/PWWP/MBT0.8999Inherited
BPTI-like0.09537Inherited
Homeodomain-like1Inherited
Radical SAM enzymes0.8463Inherited
UBA-like0.955Inherited
Cyclin-like0.008805Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    90229,63748
  • 90229 - CCCH zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    53697,53697
  • 53697 - SIS domain
  • 53697 - SIS domain
  • 0Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0Direct
    50985,48065
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    47473,57610
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.00000000000002061Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.00000000000006235Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0000000000002396Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.000000000002706Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.000000000009657Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.000000000019Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.00000000002347Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00000000002474Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0.00000000007319Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.000000000176Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.0000000002507Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.0000000002771Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.0000000002771Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.0000000004038Direct
    68906,57850
  • 68906 - SAP domain
  • 57850 - RING/U-box
  • 0.0000000004167Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0000000007375Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.00000000749Direct
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00000001203Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.00000004896Direct
    50044,56112
  • 50044 - SH3-domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000006699Direct
    48366,47473
  • 48366 - Ras GEF
  • 47473 - EF-hand
  • 0.0000002228Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.0000002533Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.0000002533Direct
    56112,54236
  • 56112 - Protein kinase-like (PK-like)
  • 54236 - Ubiquitin-like
  • 0.0000003268Direct
    56112,81837
  • 56112 - Protein kinase-like (PK-like)
  • 81837 - BEACH domain
  • 0.0000003268Direct
    55979,55979
  • 55979 - DNA clamp
  • 55979 - DNA clamp
  • 0.0000005275Direct
    48670,48097
  • 48670 - Transducin (heterotrimeric G protein), gamma chain
  • 48097 - Regulator of G-protein signaling, RGS
  • 0.0000009389Direct
    57256,57362
  • 57256 - Elafin-like
  • 57362 - BPTI-like
  • 0.00000104Direct
    50939,50939
  • 50939 - Sialidases
  • 50939 - Sialidases
  • 0.00000104Direct
    52047,48371
  • 52047 - RNI-like
  • 48371 - ARM repeat
  • 0.00000104Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.000001303Direct
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0.000002559Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.000003698Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.000006132Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0.000007733Direct
    48371,111347
  • 48371 - ARM repeat
  • 111347 - Rap/Ran-GAP
  • 0.000008188Direct
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.00001006Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.00001151Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.00001424Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.00001793Direct
    48452,48403
  • 48452 - TPR-like
  • 48403 - Ankyrin repeat
  • 0.00004345Direct
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.00004415Direct
    48350,54236
  • 48350 - GTPase activation domain, GAP
  • 54236 - Ubiquitin-like
  • 0.00004857Direct
    63491,63491
  • 63491 - BAG domain
  • 63491 - BAG domain
  • 0.00004857Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.00005858Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.00007215Direct
    57924,52540
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00009074Direct
    47923,52821
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 0.00009074Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.00009074Direct
    46565,144217
  • 46565 - Chaperone J-domain
  • 144217 - CSL zinc finger
  • 0.00009074Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0.000125Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0001274Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.0001274Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001438Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0001438Direct
    50729,48350
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.0001648Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.0001725Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0001725Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.0002433Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.0002972Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.0003025Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0003799Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0004345Direct
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0004783Direct
    46565,52833
  • 46565 - Chaperone J-domain
  • 52833 - Thioredoxin-like
  • 0.0005151Direct
    57190,57190
  • 57190 - Colipase-like
  • 57190 - Colipase-like
  • 0.0005151Direct
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.0005362Direct
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.0005362Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0009506Direct
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.0009783Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0009924Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.008478Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6303Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.02535Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.001203Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.4885Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.24Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.006224Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.7898Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.3692Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1654Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1896Inherited
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.001991Inherited
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.4609Inherited
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.3855Inherited
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.1427Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2174Inherited
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0.004799Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.1852Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.5463Inherited
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.2495Inherited
    159141,159141
  • 159141 - HIN-2000 domain-like
  • 159141 - HIN-2000 domain-like
  • 0.3108Inherited
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.317Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.9388Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0372Inherited
    48452,46565
  • 48452 - TPR-like
  • 46565 - Chaperone J-domain
  • 0.005188Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1778Inherited
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
  • 0.002767Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.4236Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.24Inherited
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 1Inherited
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.009023Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.6957Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 1Inherited
    57581,57581
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 0.0024Inherited
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.005801Inherited
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.007962Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.01505Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.01505Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03841Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1654Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.02614Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.7611Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    48552,48552
  • 48552 - Serum albumin-like
  • 48552 - Serum albumin-like
  • 0.03091Inherited
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0.001282Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1346Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.1293Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.4626Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.4477Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.3002Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.01353Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.08008Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1778Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.1778Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.01776Inherited
    50044,48350
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 0.01015Inherited
    48350,55550
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0.08174Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.2707Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 1Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.3108Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.005191Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.004554Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.009505Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.006224Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.06213Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.26Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.03284Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3648Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.6274Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.6274Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.7685Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0159Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.7238Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.01051Inherited
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.24Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.002625Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.004352Inherited
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.006792Inherited
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.01271Inherited
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.03091Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.06548Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 1Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.01159Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.01302Inherited
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.02614Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.004017Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.006224Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.7582Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.07145Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.3648Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 1Inherited
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.03884Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.5099Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.7429Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 1Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 1Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.01641Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3203Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.3855Inherited
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.6337Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.02307Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.004624Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.008797Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.9839Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.9839Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.7114Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.9995Inherited
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0.24Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.08269Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    48065,50729,82185
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    48403,48452,48403
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 48403 - Ankyrin repeat
  • 0Direct
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    50985,48065,50729
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    100895,47473,57610
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.000000000000007352Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0000000000629Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.0000000001067Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0000000002507Direct
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000000001598Direct
    47031,50729,55550
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.000000001873Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.000000008768Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.00000002523Direct
    55550,50044,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.000000033Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000006699Direct
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0000001301Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000001634Direct
    48366,47473,57889
  • 48366 - Ras GEF
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0.0000002228Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000007552Direct
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000104Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000001842Direct
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.000001902Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000416Direct
    48065,50729,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.000005149Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.000007733Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000008188Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000008188Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.00001151Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00001277Direct
    50044,55550,50044
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00001739Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00002805Direct
    50729,49562,48350
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.00004345Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.00004415Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.00004857Direct
    63491,63491,63491
  • 63491 - BAG domain
  • 63491 - BAG domain
  • 63491 - BAG domain
  • 0.00004857Direct
    57924,57924,52540
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00004857Direct
    46565,52833,52833
  • 46565 - Chaperone J-domain
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.00004857Direct
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.00005433Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.00006423Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.0001162Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0001274Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0001274Direct
    55008,55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0.0002424Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0003025Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.0003025Direct
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.0008494Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.7114Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.3692Inherited
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.1852Inherited
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.4609Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2174Inherited
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.001632Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.003702Inherited
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.003969Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.121Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1066Inherited
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.9839Inherited
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.01505Inherited
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 1Inherited
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 1Inherited
    57581,57196,57184
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.002767Inherited
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.003609Inherited
    57581,57581,57184
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.004304Inherited
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.005188Inherited
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.005801Inherited
    57581,57184,57196
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.006853Inherited
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.009683Inherited
    57184,57581,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57581 - TB module/8-cys domain
  • 0.01159Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01385Inherited
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.01458Inherited
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.01985Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04732Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.01623Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7611Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.004624Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.641Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.0514Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.06569Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.0514Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.7114Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.05015Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.1778Inherited
    50044,48350,55550
  • 50044 - SH3-domain
  • 48350 - GTPase activation domain, GAP
  • 55550 - SH2 domain
  • 0.08174Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 1Inherited
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.1101Inherited
    51905,51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.4021Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.6274Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.6274Inherited
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02052Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.394Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.006853Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.006853Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.009023Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.003702Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.8135Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.007097Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.008926Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1427Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3855Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1081Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.24Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 1Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3855Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.3855Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.004094Inherited


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