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Biological Process (BP): regulation of cellular process

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + 2:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ 1:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
0:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
- 1:   negative regulation of cellular process [GO:0048523] <65>(61|62) (404|394|222)
- 1:   positive regulation of cellular process [GO:0048522] <59>(61|67) (417|418|244)
- 1:   regulation of cellular metabolic process [GO:0031323] <53>(83|84) (491|483|246)
- 1:   regulation of cellular component organization [GO:0051128] <52>(35|32) (311|310|174)
- 1:   signal transduction [GO:0007165] <42>(43|39) (314|330|196)
- 1:   regulation of cell differentiation [GO:0045595] <39>(20|19) (208|207|121)
- 1:   regulation of cell proliferation [GO:0042127] <33>(17|22) (134|105|56)
- 1:   regulation of cellular response to stress [GO:0080135] <29>(7|6) (118|78|31)
- 1:   regulation of cell communication [GO:0010646] <25>(42|44) (331|347|194)
- 1:   regulation of vesicle-mediated transport [GO:0060627] <18>(8|8) (85|64|38)
- 1:   regulation of cellular response to growth factor stimulus [GO:0090287] <11>(5|4) (75|63|52)
- 1:   regulation of secretion by cell [GO:1903530] <11>(13|13) (98|56|26)
- 1:   regulation of cell division [GO:0051302] <10>(3|4) (34|19|7)
- 1:   regulation of cell wall organization or biogenesis [GO:1903338] <10>(0|0) (6|2|0)
- 1:   regulation of cell cycle [GO:0051726] <9>(14|18) (145|100|41)
- 1:   regulation of cell activation [GO:0050865] <8>(7|8) (78|63|29)
- 1:   regulation of chromosome segregation [GO:0051983] <8>(5|5) (30|10|3)
- 1:   regulation of cell death [GO:0010941] <6>(17|22) (153|158|74)
- 1:   regulation of cellular component movement [GO:0051270] <6>(11|10) (111|117|83)
- 1:   regulation of membrane depolarization [GO:0003254] <6>(0|0) (6|0|0)
- 1:   regulation of phenotypic switching [GO:1900239] <6>(0|0) (1|0|0)
- 1:   regulation of cell aging [GO:0090342] <5>(0|0) (12|9|6)
- 1:   regulation of peroxidase activity [GO:2000468] <5>(0|0) (0|0|0)
- 1:   regulation of potassium ion transmembrane transport [GO:1901379] <5>(1|1) (16|5|1)
- 1:   regulation of protein folding [GO:1903332] <5>(0|0) (2|1|1)
- 1:   regulation of single-species biofilm formation [GO:1900190] <5>(0|0) (11|5|1)
- 1:   regulation of transposition [GO:0010528] <5>(1|0) (7|4|0)
- 1:   regulation of calcium ion transport into cytosol [GO:0010522] <4>(4|3) (20|11|4)
- 1:   regulation of cellular pH reduction [GO:0032847] <4>(1|1) (4|0|0)
- 1:   regulation of cellular response to insulin stimulus [GO:1900076] <4>(2|1) (16|14|6)
- 1:   regulation of establishment or maintenance of cell polarity [GO:0032878] <4>(1|1) (10|7|4)
- 1:   regulation of gene silencing [GO:0060968] <4>(1|0) (33|13|4)
- 1:   regulation of actin filament-based process [GO:0032970] <3>(5|6) (71|50|28)
- 1:   regulation of cellular response to alcohol [GO:1905957] <3>(1|0) (5|0|0)
- 1:   regulation of cellular response to macrophage colony-stimulating factor stimulus [GO:1903972] <3>(0|0) (1|0|0)
- 1:   regulation of conjugation [GO:0046999] <3>(0|0) (7|2|1)
- 1:   regulation of cytolysis [GO:0042268] <3>(1|2) (4|1|1)
- 1:   regulation of response to cell cycle checkpoint signaling [GO:1902145] <3>(0|0) (1|0|0)
- 1:   regulation of sequestering of calcium ion [GO:0051282] <3>(3|2) (30|21|9)
- 1:   regulation of cell adhesion molecule production [GO:0060353] <2>(0|0) (0|0|0)
- 1:   regulation of cellular response to X-ray [GO:2000683] <2>(0|0) (3|1|0)
- 1:   regulation of cellular response to drug [GO:2001038] <2>(0|0) (2|0|0)
- 1:   regulation of cellular response to gamma radiation [GO:1905843] <2>(0|0) (0|0|0)
- 1:   regulation of cellular response to manganese ion [GO:1905802] <2>(0|0) (0|0|0)
- 1:   regulation of cellular response to oxidopamine [GO:1905846] <2>(0|0) (0|0|0)
- 1:   regulation of cellular response to thapsigargin [GO:1905891] <2>(0|0) (0|0|0)
- 1:   regulation of cellular response to tunicamycin [GO:1905894] <2>(0|0) (0|0|0)
- 1:   regulation of cellular response to very-low-density lipoprotein particle stimulus [GO:1905890] <2>(0|0) (0|0|0)
- 1:   regulation of melanosome transport [GO:1902908] <2>(0|0) (0|0|0)
- 1:   regulation of microtubule-based process [GO:0032886] <2>(4|3) (41|30|12)
- 1:   regulation of myelination [GO:0031641] <2>(0|0) (11|5|0)
- 1:   regulation of sequestering of zinc ion [GO:0061088] <2>(0|0) (2|1|0)
- 1:   regulation of stomatal movement [GO:0010119] <2>(0|0) (4|0|0)
- 1:   regulation of binding of sperm to zona pellucida [GO:2000359] <1>(1|1) (1|0|0)
- 1:   regulation of cellular response to alkaline pH [GO:1900067] <1>(0|0) (0|0|0)
- 1:   regulation of cellular response to testosterone stimulus [GO:2000654] <1>(0|0) (0|0|0)
- 1:   cell redox homeostasis [GO:0045454](2|3) (9|3|0)
- 1:   regulation of Cvt pathway [GO:2001159](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
"Winged helix" DNA-binding domain0.0005380.0000000008509Direct
Actin depolymerizing proteins0.0000068350.0000005003Direct
Apolipoprotein A-II0.0000010720.00007863Direct
Bcl-2 inhibitors of programmed cell death00Direct
Caspase-like0.00000010440.00000000009424Direct
Core binding factor beta, CBF0.0000000022790.00000005095Direct
Family A G protein-coupled receptor-like0.000052570.000000000007744Direct
Histidine-containing phosphotransfer domain, HPT domain0.00000011810.00001411Direct
Inhibitor of apoptosis (IAP) repeat00Direct
PhoU-like0.000000000000016390.00000006904Direct
Protein kinase-like (PK-like)0.000000076840.000003039Direct
Regulator of G-protein signaling, RGS0.0000000000010290.0000004491Direct
Roadblock/LC7 domain00.0000002165Direct
Subunits of heterodimeric actin filament capping protein Capz0.0000000010520.00001241Direct
The spindle assembly checkpoint protein mad20.0000000000094570.00000001186Direct
Transducin (heterotrimeric G protein), gamma chain0.000000000010410.00000000000001763Direct
VHL0.000044010.0004369Direct
Metalloproteases ("zincins"), catalytic domain11Inherited
4-helical cytokines0.23770.3096Inherited
Cytidine deaminase-like0.11260.3645Inherited
SNF-like0.3991Inherited
p53-like transcription factors0.0059830.0000001389Inherited
SRF-like0.0088431Inherited
UBC-like0.83890.8464Inherited
Annexin0.022310.2365Inherited
Interleukin 8-like chemokines0.0026080.0222Inherited
Defensin-like0.0016040.8476Inherited
Class I glutamine amidotransferase-like11Inherited
HIT-like0.3021Inherited
Gamma-glutamyl cyclotransferase-like0.67461Inherited
Spermadhesin, CUB domain01Inherited
TPR-like11Inherited
L30e-like0.70381Inherited
E set domains0.047240.0001168Inherited
NAD(P)-binding Rossmann-fold domains11Inherited
Sec1/munc18-like (SM) proteins0.52020.9513Inherited
PX domain0.014390.121Inherited
SNARE fusion complex0.3021Inherited
Phosphoglycerate mutase-like0.00017411Inherited
NAD(P)-linked oxidoreductase11Inherited
Cell cycle regulatory proteins0.00058070.009017Inherited
P-loop containing nucleoside triphosphate hydrolases0.00000000013831Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)11Inherited
Lipocalins11Inherited
Metallo-dependent hydrolases0.028661Inherited
Immunoglobulin0.00041860.02586Inherited
KRAB domain (Kruppel-associated box)0.57211Inherited
Carbohydrate phosphatase0.11Inherited
Activating enzymes of the ubiquitin-like proteins0.12751Inherited
Cytochrome P4500.77481Inherited
Nuclear receptor ligand-binding domain0.0031751Inherited
Nudix0.99151Inherited
Calcium-dependent phosphotriesterase0.0033431Inherited
Concanavalin A-like lectins/glucanases0.26570.8942Inherited
(Trans)glycosidases11Inherited
Nucleoside diphosphate kinase, NDK11Inherited
RNase A-like0.099510.08202Inherited
ALDH-like11Inherited
Aquaporin-like11Inherited
UDP-Glycosyltransferase/glycogen phosphorylase11Inherited
Kazal-type serine protease inhibitors0.43521Inherited
Serpins0.50281Inherited
TIMP-like0.000000015010.5561Inherited
Cystatin/monellin0.87791Inherited
Homeodomain-like0.1950.0000000000002873Inherited
HLH, helix-loop-helix DNA-binding domain0.86720.00000000000002769Inherited
FAD/NAD(P)-binding domain0.2521Inherited
Thioredoxin-like11Inherited
Clavaminate synthase-like11Inherited
Cyclophilin-like11Inherited
Metallothionein11Inherited
Cu,Zn superoxide dismutase-like0.12750.4933Inherited
Cytokine0.39250.3364Inherited
14-3-3 protein11Inherited
Nqo5-like0.028010.7705Inherited
Insulin-like0.099510.2746Inherited
Ankyrin repeat0.11150.0001463Inherited
Ferritin-like0.28731Inherited
CheY-like0.000016560.001029Inherited
Casein kinase II beta subunit0.00000036530.6681Inherited
Radical SAM enzymes11Inherited
PRTase-like0.28751Inherited
Arginase/deacetylase0.20030.01912Inherited
WD40 repeat-like0.47950.0795Inherited
Stathmin0.0000002160.004629Inherited
Calponin-homology domain, CH-domain0.75450.4386Inherited
Arp2/3 complex subunits0.0035360.01898Inherited
Arp2/3 complex 21 kDa subunit ARPC30.028010.3186Inherited
Nucleic acid-binding proteins0.25841Inherited
DEATH domain0.000066920.01876Inherited
Profilin (actin-binding protein)0.00000059660.002996Inherited
Ubiquitin-like0.20280.00002609Inherited
Proteasome activator0.00015420.009017Inherited
RelE-like0.90381Inherited
HMG-box0.032330.000002404Inherited
beta-beta-alpha zinc fingers0.3020.000000009011Inherited
ssDNA-binding transcriptional regulator domain0.0024530.0152Inherited
Putative DNA-binding domain0.0000000019631Inherited
Ribbon-helix-helix11Inherited
ARM repeat0.14020.3279Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.00044481Inherited
Cysteine proteinases0.09010.1828Inherited
alpha/beta-Hydrolases11Inherited
FKBP-like0.013950.4836Inherited
HAD-like11Inherited
C-type lectin-like0.31091Inherited
Mitochondrial carrier11Inherited
Cystine-knot cytokines0.0083650Inherited
(Phosphotyrosine protein) phosphatases II0.43430.01929Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.49130.2537Inherited
RING/U-box0.08350.1967Inherited
FMN-linked oxidoreductases11Inherited
Bet v1-like0.48131Inherited
Nucleotide-diphospho-sugar transferases11Inherited
Trypsin-like serine proteases11Inherited
PDZ domain-like0.059760.02467Inherited
Carbonic anhydrase11Inherited
LanC-like0.0000057090.00129Inherited
Cupredoxins0.51891Inherited
S-adenosyl-L-methionine-dependent methyltransferases11Inherited
Ribonuclease H-like11Inherited
Pentein0.038851Inherited
eIF4e-like0.171Inherited
YjgF-like0.80491Inherited
PIN domain-like11Inherited
Ribosome inactivating proteins (RIP)0.0044570.05259Inherited
Tetrapyrrole methylase0.053541Inherited
CSL zinc finger0.000360.04412Inherited
RNA-binding domain, RBD10.7141Inherited
Prefoldin0.027990.7823Inherited
IHF-like DNA-binding proteins0.012160.193Inherited
lambda repressor-like DNA-binding domains0.18760.008212Inherited
Histone-fold0.40310.3325Inherited
NTF2-like11Inherited
L domain-like0.46510.00795Inherited
RNI-like11Inherited
EF-hand0.12370.1437Inherited
N-(deoxy)ribosyltransferase-like0.00065340.001367Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Apolipoprotein A-II0.0000018630.0001259Direct
B56-like0.00000000017440.00000000107Direct
Bcl-2 inhibitors of programmed cell death00Direct
Bee venom hyaluronidase0.00000000050950.0000000009778Direct
Capz beta-1 subunit0.0000000000023010.00000001004Direct
Caspase catalytic domain0.00000027710.000000000005439Direct
Cell cycle arrest protein BUB30.0000000000087520.000003658Direct
Cofilin-like0.000024040.0007348Direct
Core binding factor beta, CBF0.0000000065160.0000001621Direct
DNA-binding N-terminal domain of transcription activators0.00000000290.000002027Direct
FIS-like00.000002226Direct
FUR-like00Direct
G proteins0.00000000020080.00002515Direct
Inhibitor of apoptosis (IAP) repeat00Direct
LanC-like0.0000043330.0006508Direct
MarR-like transcriptional regulators0.00000000017940.00000001842Direct
N-deoxyribosyltransferase0.0000018920.0002023Direct
Paired domain00Direct
Phosphorelay protein-like0.0000000090470.000006678Direct
PhoU-like0.0000000000000055430.000000012Direct
Platelet-derived growth factor-like0.000086210Direct
Protein kinases, catalytic subunit0.00000024730.000009448Direct
Regulator of G-protein signaling, RGS0.0000000000040380.0000006787Direct
Renal dipeptidase0.000000000000033180.00001183Direct
Rhodopsin-like0.00032420.000000003209Direct
Roadblock/LC7 domain0.000000000000021130.000007494Direct
The spindle assembly checkpoint protein mad20.000000000052580.000002663Direct
Tissue inhibitor of metalloproteinases, TIMP0.000000014560.0001516Direct
Transducin (heterotrimeric G protein), gamma chain0.000000000080660.00000000002839Direct
VHL0.000069620.0006889Direct
Short-chain cytokines0.30320.8684Inherited
Arginine methyltransferase0.0083861Inherited
SNF-like0.50541Inherited
PP1699/LP2961-like0.46791Inherited
Pentraxin (pentaxin)0.030170.1004Inherited
Interleukin 17F, IL-17F0.41721Inherited
SRF-like0.0057661Inherited
UBC-related0.81911Inherited
Penta-EF-hand proteins0.0016580.00002627Inherited
Annexin0.022710.4543Inherited
Interleukin 8-like chemokines0.0031380.02587Inherited
Defensin0.000000028110.07793Inherited
DJ-1/PfpI0.35021Inherited
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0.25521Inherited
Spermadhesin, CUB domain01Inherited
Tetratricopeptide repeat (TPR)0.88451Inherited
Tyrosine-dependent oxidoreductases11Inherited
Sec1/munc18-like (SM) proteins0.50550.9943Inherited
PX domain0.019810.375Inherited
SNARE fusion complex0.29131Inherited
Histidine acid phosphatase0.0000000000040340.02548Inherited
RING finger domain, C3HC40.025840.5503Inherited
Aldo-keto reductases (NADP)11Inherited
Cell cycle regulatory proteins0.0009760.01419Inherited
Proteasome subunits11Inherited
Retinol binding protein-like11Inherited
KRAB domain (Kruppel-associated box)0.67341Inherited
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0.13081Inherited
Cofactor-dependent phosphoglycerate mutase0.060780.9043Inherited
Ubiquitin activating enzymes (UBA)0.00066690.6864Inherited
Nuclear receptor ligand-binding domain0.0054751Inherited
MutT-like0.71351Inherited
C5 cytosine-specific DNA methylase, DCM0.011390.6249Inherited
V set domains (antibody variable domain-like)0.0004140.7985Inherited
Interferons/interleukin-10 (IL-10)0.94161Inherited
Calmodulin-like0.8321Inherited
Nucleoside diphosphate kinase, NDK11Inherited
Ribonuclease A-like0.097980.08034Inherited
Forkhead DNA-binding domain0.0057660.0003203Inherited
Transforming growth factor (TGF)-beta0.0026090.00000000000000307Inherited
ALDH-like11Inherited
Aquaporin-like11Inherited
UDPGT-like11Inherited
Astacin0.56871Inherited
Cystatins0.13970.8196Inherited
Ovomucoid domain III-like0.53111Inherited
Serpins0.51430.9901Inherited
HLH, helix-loop-helix DNA-binding domain0.84310.0000000000001843Inherited
Homeodomain0.77450.000003206Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.0083861Inherited
Glutathione peroxidase-like0.83041Inherited
Thioltransferase11Inherited
Thioesterases0.0099050.2673Inherited
Cyclophilin (peptidylprolyl isomerase)11Inherited
Metallothionein11Inherited
Cu,Zn superoxide dismutase-like0.12480.6791Inherited
14-3-3 protein11Inherited
Cystathionine synthase-like11Inherited
Nqo5-like0.040230.768Inherited
Glyoxalase I (lactoylglutathione lyase)0.01290.944Inherited
S100 proteins0.0000052370.05517Inherited
Insulin-like0.097980.283Inherited
Ankyrin repeat0.12510.0003646Inherited
beta 1,4 galactosyltransferase (b4GalT1)0.0027380.5609Inherited
Ferritin0.071561Inherited
CheY-related0.000040280.003961Inherited
Cytochrome P4500.89861Inherited
Casein kinase II beta subunit0.000001170.6404Inherited
MoCo biosynthesis proteins0.12441Inherited
Phosphoribosyltransferases (PRTases)0.34171Inherited
Molybdenum cofactor biosynthesis protein MoeB0.91591Inherited
Histone deacetylase, HDAC0.035940.02602Inherited
Galectin (animal S-lectin)0.0080470.9062Inherited
Interleukin-1 (IL-1)11Inherited
Long-chain cytokines0.0021380.00002315Inherited
Stathmin0.0000005960.009041Inherited
Calponin-homology domain, CH-domain0.72640.4701Inherited
Arp2/3 complex subunits0.0049620.03425Inherited
Arp2/3 complex 21 kDa subunit ARPC30.040230.3852Inherited
Cold shock DNA-binding domain-like0.16081Inherited
Profilin (actin-binding protein)0.0000021850.007072Inherited
Capz alpha-1 subunit0.02570.2262Inherited
Proteasome activator0.00026410.01419Inherited
GABARAP-like0.37040.8341Inherited
Dimethylarginine dimethylaminohydrolase DDAH0.0021890.04611Inherited
ArsR-like transcriptional regulators0.00022630.006647Inherited
WD40-repeat0.76020.3234Inherited
Arylsulfatase0.92360.3356Inherited
Classic zinc finger, C2H20.41720.0000000000892Inherited
GreA transcript cleavage factor, C-terminal domain0.0023190.07151Inherited
Formate/glycerate dehydrogenases, substrate-binding domain0.00058220.6455Inherited
FKBP immunophilin/proline isomerase0.1240.5965Inherited
NLI interacting factor-like phosphatase0.000058820.3824Inherited
C-type lectin domain0.33361Inherited
Mitochondrial carrier11Inherited
SGL-like0.000082510.05817Inherited
Gonadodropin/Follitropin0.022710.0543Inherited
Dual specificity phosphatase-like0.1960.03279Inherited
APC10-like0.00053310.02497Inherited
HEAT repeat0.0017110.1038Inherited
Carboxylesterase0.92111Inherited
FMN-linked oxidoreductases11Inherited
Cyclin A/CDK2-associated p19, Skp20.53110.5681Inherited
Eukaryotic proteases11Inherited
RhoGDI-like0.00011530.1075Inherited
Carbonic anhydrase11Inherited
Fibroblast growth factors (FGF)0.01780.0207Inherited
Ephrin ectodomain0.000022690.04927Inherited
NOL1/NOP2/sun0.0057660.9713Inherited
CAF1-like ribonuclease11Inherited
Ribosome anti-association factor eIF6 (aIF6)0.0037330.07074Inherited
Pumilio repeat0.67311Inherited
Translation initiation factor eIF4e0.26731Inherited
YjgF/L-PSP0.77451Inherited
Plant cytotoxins0.0023190.04611Inherited
Tetrapyrrole methylase0.075021Inherited
CSL zinc finger0.00056330.06763Inherited
Canonical RBD10.8437Inherited
Prefoldin0.029440.7826Inherited
Prokaryotic DNA-bending protein0.017880.2063Inherited
Transcriptional coactivator PC4 C-terminal domain0.0021890.03246Inherited
TBP-associated factors, TAFs0.047040.03719Inherited
C1 set domains (antibody constant domain-like)0.41720.6805Inherited
Papain-like0.17661Inherited


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Supra-domain (including individual superfamily)

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