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Biological Process (BP): negative regulation of synaptic transmission

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   biological_process [GO:0008150] <24>
+ + + + 4:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + 3:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + 3:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + 2:   negative regulation of biological process [GO:0048519] <52>(72|76) (445|449|253)
+ + 2:   negative regulation of cellular process [GO:0048523] <65>(61|62) (404|394|222)
+ + 2:   regulation of cell communication [GO:0010646] <25>(42|44) (331|347|194)
+ + 2:   regulation of signaling [GO:0023051] <13>(42|44) (331|349|197)
+ 1:   modulation of chemical synaptic transmission [GO:0050804] <22>(2|2) (64|49|18)
+ 1:   negative regulation of cell communication [GO:0010648] <17>(13|9) (193|165|90)
+ 1:   negative regulation of signaling [GO:0023057] <10>(13|10) (193|165|90)
0:   negative regulation of synaptic transmission [GO:0050805] <10>(0|0) (15|8|2)
- 1:   negative regulation of neurotransmitter secretion [GO:0046929] <7>(0|0) (5|3|1)
- 1:   negative regulation of excitatory postsynaptic potential [GO:0090394] <2>(0|0) (1|0|0)
- 1:   negative regulation of synaptic transmission, cholinergic [GO:0032223] <2>(0|0) (0|0|0)
- 1:   negative regulation by symbiont of host synaptic transmission [GO:0044759] <1>(0|0) (0|0|0)
- 1:   negative regulation of synaptic transmission, dopaminergic [GO:0032227] <1>(0|0) (0|0|0)
- 1:   negative regulation of synaptic transmission, glutamatergic [GO:0051967] <1>(0|0) (3|0|0)
- 1:   negative regulation of synaptic transmission, glycinergic [GO:0060093] <1>(0|0) (0|0|0)
- 1:   long term synaptic depression [GO:0060292](0|0) (3|3|0)
- 1:   negative regulation of neuromuscular synaptic transmission [GO:1900074](0|0) (2|1|1)
- 1:   negative regulation of synaptic transmission, GABAergic [GO:0032229](0|0) (1|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF-like0Direct
Ankyrin repeat0.000000000001065Direct
Periplasmic binding protein-like I0.00000000009389Direct
DEATH domain0.0000000002151Direct
Eukaryotic type KH-domain (KH-domain type I)0.0000001718Direct
Polo-box domain0.0000007203Direct
PDZ domain-like0.000001902Direct
beta-sandwich domain of Sec23/240.000005203Direct
BAR/IMD domain-like0.00002437Direct
Transducin (alpha subunit), insertion domain0.00005814Direct
alpha/beta-Hydrolases0.001211Inherited
Family A G protein-coupled receptor-like0.00293Inherited
Periplasmic binding protein-like II0.004032Inherited
p53-like transcription factors0.001389Inherited
E set domains0.002443Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0Direct
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.0000000002458Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.00000001273Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.00000008207Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.0000007203Direct
    81995,49417
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 0.00001307Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.00005814Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00005814Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,49417,81296
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.000000002394Direct


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