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Biological Process (BP): regulation of small GTPase mediated signal transduction

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   biological_process [GO:0008150] <24>
+ + + + + 5:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + + 4:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + + + 4:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ + + 3:   regulation of cell communication [GO:0010646] <25>(42|44) (331|347|194)
+ + + 3:   regulation of response to stimulus [GO:0048583] <43>(57|53) (384|420|248)
+ + + 3:   regulation of signaling [GO:0023051] <13>(42|44) (331|349|197)
+ + 2:   regulation of signal transduction [GO:0009966] <71>(39|40) (308|319|183)
+ 1:   regulation of intracellular signal transduction [GO:1902531] <25>(18|23) (194|173|89)
0:   regulation of small GTPase mediated signal transduction [GO:0051056] <4>(1|2) (50|43|22)
- 1:   regulation of Ras protein signal transduction [GO:0046578] <10>(1|2) (45|33|14)
- 1:   modulation by symbiont of host small GTPase mediated signal transduction [GO:0044082] <1>(0|0) (0|0|0)
- 1:   negative regulation of small GTPase mediated signal transduction [GO:0051058] <1>(1|1) (18|12|4)
- 1:   positive regulation of small GTPase mediated signal transduction [GO:0051057] <1>(0|0) (24|16|11)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Carbohydrate phosphatase00.00000000001486Direct


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Inositol monophosphatase/fructose-1,6-bisphosphatase-like00.00000000002346Direct
RhoGDI-like0.0000000005950.0000003539Direct


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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PH domain-like0Direct
Ras GEF0Direct
GTPase activation domain, GAP0Direct
DBL homology domain (DH-domain)0Direct
Sec7 domain0.000000000000006464Direct
SH3-domain0.000000000003571Direct
CRAL/TRIO domain0.000000000005282Direct
Carbohydrate phosphatase0.000000000008399Direct
BAR/IMD domain-like0.00000000004196Direct
Cysteine-rich domain0.00000001836Direct
beta-sandwich domain of Sec23/240.00000005898Direct
Stathmin0.0000003455Direct
Sialidases0.000002821Direct
FF domain0.000003348Direct
ArfGap/RecO-like zinc finger0.000004245Direct
Spectrin repeat0.000004602Direct
POZ domain0.000006699Direct
RUN domain-like0.000007569Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00009598Direct
Cullin homology domain0.0004094Direct
VPS9 domain0.0007814Direct
Chromo domain-like0.01075Inherited
beta-beta-alpha zinc fingers0.3345Inherited
Plexin repeat0.5757Inherited
SAM/Pointed domain0.06771Inherited
Cullin repeat-like0.001271Inherited
Bet v1-like0.001854Inherited
E set domains0.001337Inherited
Histone-fold0.003303Inherited
PP2C-like0.4569Inherited
p53-like transcription factors0.5609Inherited
EGF/Laminin0.002918Inherited
L domain-like0.09973Inherited
Quinoprotein alcohol dehydrogenase-like0.007556Inherited
14-3-3 protein0.001962Inherited
Family A G protein-coupled receptor-like0.133Inherited
Notch domain0.03399Inherited
Regulator of G-protein signaling, RGS0.005334Inherited
PDZ domain-like0.009549Inherited
Immunoglobulin0.6572Inherited
NAD kinase/diacylglycerol kinase-like0.001822Inherited
Protein serine/threonine phosphatase 2C, C-terminal domain0.1967Inherited
Ypt/Rab-GAP domain of gyp1p0.006128Inherited
ARM repeat0.001959Inherited
FnI-like domain0.1548Inherited
Fibronectin type III0.9228Inherited
"Winged helix" DNA-binding domain0.05419Inherited
cAMP-binding domain-like0.07115Inherited
Ubiquitin-like0.5228Inherited
(Phosphotyrosine protein) phosphatases II1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50729,48350
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    50729,48366
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.00000000000004467Direct
    47113,48065
  • 47113 - Histone-fold
  • 48065 - DBL homology domain (DH-domain)
  • 0.00000000000008397Direct
    48366,57889
  • 48366 - Ras GEF
  • 57889 - Cysteine-rich domain
  • 0.00000000000008397Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.0000000000006195Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.000000000005541Direct
    50044,140741
  • 50044 - SH3-domain
  • 140741 - RUN domain-like
  • 0.00000000001477Direct
    50939,50939
  • 50939 - Sialidases
  • 50939 - Sialidases
  • 0.0000000002682Direct
    81995,49417
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 0.00000001129Direct
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0.0000001356Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.0000001356Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.0000001954Direct
    52087,48350
  • 52087 - CRAL/TRIO domain
  • 48350 - GTPase activation domain, GAP
  • 0.0000003795Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.0000005785Direct
    103657,48350
  • 103657 - BAR/IMD domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.0000008449Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000009272Direct
    57863,50729
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 0.000003634Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.000004245Direct
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.00000753Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.00002016Direct
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.00003007Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.00007098Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0002218Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.0004094Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0004094Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.3115Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.002039Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.006029Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.005102Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.03113Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.03399Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.04407Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.1967Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.3372Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.006128Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01755Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.05602Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48065,50729,48366
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 48366 - Ras GEF
  • 0Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    81995,49417,81296
  • 81995 - beta-sandwich domain of Sec23/24
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    47113,48065,50729
  • 47113 - Histone-fold
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.00000000001477Direct
    50729,50729,48350
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.000000001469Direct
    50729,50729,57863
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.000000001469Direct
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0.00000001996Direct
    50729,57863,50729
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 0.00000003189Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.00000007075Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0000005785Direct
    57863,50729,50729
  • 57863 - ArfGap/RecO-like zinc finger
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.000003634Direct
    50729,49562,48350
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.00007806Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0004094Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03113Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.03399Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.05602Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.03399Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03399Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.05602Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.05602Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9118Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.3463Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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