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Biological Process (BP): negative regulation of cellular component organization

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   biological_process [GO:0008150] <24>
+ + + + 4:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + + 3:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ + 2:   negative regulation of biological process [GO:0048519] <52>(72|76) (445|449|253)
+ + 2:   regulation of cellular process [GO:0050794] <58>(138|154) (661|802|451)
+ 1:   negative regulation of cellular process [GO:0048523] <65>(61|62) (404|394|222)
+ 1:   regulation of cellular component organization [GO:0051128] <52>(35|32) (311|310|174)
0:   negative regulation of cellular component organization [GO:0051129] <46>(13|10) (141|103|53)
- 1:   negative regulation of protein complex assembly [GO:0031333] <26>(4|4) (28|12|9)
- 1:   negative regulation of organelle organization [GO:0010639] <21>(9|8) (86|49|24)
- 1:   negative regulation of cell projection organization [GO:0031345] <11>(2|1) (50|42|28)
- 1:   negative regulation of supramolecular fiber organization [GO:1902904] <11>(5|5) (39|22|15)
- 1:   negative regulation of synapse organization [GO:1905809] <8>(0|0) (20|10|3)
- 1:   negative regulation of endocytosis [GO:0045806] <5>(0|0) (9|6|1)
- 1:   negative regulation of protein complex disassembly [GO:0043242] <5>(3|3) (27|14|12)
- 1:   negative regulation of cell morphogenesis involved in differentiation [GO:0010771] <4>(2|1) (37|27|22)
- 1:   negative regulation of extracellular matrix organization [GO:1903054] <4>(0|0) (3|1|0)
- 1:   negative regulation of cell junction assembly [GO:1901889] <3>(1|1) (4|1|0)
- 1:   negative regulation of iron-sulfur cluster assembly [GO:1903330] <2>(0|0) (0|0|0)
- 1:   negative regulation of protein localization to plasma membrane [GO:1903077] <2>(0|0) (1|0|0)
- 1:   negative regulation of syncytium formation by plasma membrane fusion [GO:0034242] <2>(0|0) (0|0|0)
- 1:   negative regulation of unidimensional cell growth [GO:0051511] <2>(0|0) (0|0|0)
- 1:   negative regulation of adherens junction organization [GO:1903392] <1>(1|1) (3|1|0)
- 1:   negative regulation of blood microparticle formation [GO:2000333] <1>(0|0) (0|0|0)
- 1:   negative regulation of cell septum assembly [GO:1901892] <1>(0|0) (0|0|0)
- 1:   negative regulation of inclusion body assembly [GO:0090084] <1>(0|0) (1|0|0)
- 1:   negative regulation of integrin biosynthetic process [GO:0045720] <1>(0|0) (2|1|0)
- 1:   negative regulation of membrane invagination [GO:1905154] <1>(0|0) (1|0|0)
- 1:   negative regulation of apoptotic DNA fragmentation [GO:1902511](0|0) (0|0|0)
- 1:   negative regulation of barbed-end actin filament capping [GO:2000813](0|0) (1|0|0)
- 1:   negative regulation of capsule organization [GO:1901914](0|0) (0|0|0)
- 1:   negative regulation of clathrin-coated pit assembly [GO:1905469](0|0) (0|0|0)
- 1:   negative regulation of formation of translation initiation ternary complex [GO:1901191](0|0) (0|0|0)
- 1:   negative regulation of formation of translation preinitiation complex [GO:1901194](0|0) (1|0|0)
- 1:   negative regulation of fusion of sperm to egg plasma membrane [GO:0043013](0|0) (0|0|0)
- 1:   negative regulation of fusion of virus membrane with host plasma membrane [GO:1903914](0|0) (0|0|0)
- 1:   negative regulation of hyaluranon cable assembly [GO:1900105](0|0) (0|0|0)
- 1:   negative regulation of maintenance of mitotic actomyosin contractile ring localization [GO:1903484](0|0) (0|0|0)
- 1:   negative regulation of membrane tubulation [GO:1903526](0|0) (0|0|0)
- 1:   negative regulation of occluding junction disassembly [GO:1905074](0|0) (0|0|0)
- 1:   negative regulation of phosphatidylserine exposure on apoptotic cell surface [GO:1905781](0|0) (0|0|0)
- 1:   negative regulation of phospholipid scramblase activity [GO:1900162](0|0) (0|0|0)
- 1:   negative regulation of phospholipid translocation [GO:0061093](0|0) (0|0|0)
- 1:   negative regulation of plant-type cell wall cellulose biosynthetic process [GO:2001010](0|0) (0|0|0)
- 1:   negative regulation of plant-type cell wall cellulose catabolic process [GO:2000940](0|0) (0|0|0)
- 1:   negative regulation of plasma membrane raft polarization [GO:1903907](0|0) (0|0|0)
- 1:   negative regulation of plasma membrane repair [GO:1905685](0|0) (0|0|0)
- 1:   negative regulation of pole plasm oskar mRNA localization [GO:0045855](0|0) (0|0|0)
- 1:   negative regulation of symbiont cell wall strengthening involved in entry into host [GO:0075051](0|0) (0|0|0)
- 1:   negative regulation of synapse structural plasticity [GO:0051826](0|0) (0|0|0)
- 1:   negative regulation of synaptic vesicle membrane organization [GO:1901633](0|0) (0|0|0)
- 1:   negative regulation of telomerase catalytic core complex assembly [GO:1904883](0|0) (0|0|0)
- 1:   negative regulation of very-low-density lipoprotein particle remodeling [GO:0010903](0|0) (0|0|0)
- 1:   negative regulation of vitellogenesis [GO:1903187](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Calponin-homology domain, CH-domain0.000035470Direct
Lipocalins0.00000029850.0000002698Direct
Metallothionein0.00000000083140.0000006961Direct
Profilin (actin-binding protein)0.000000058460.0000001917Direct
Stathmin0.0000017510.00000446Direct
Subunits of heterodimeric actin filament capping protein Capz0.0000000040640.000000002686Direct
The spindle assembly checkpoint protein mad20.0000044270.00000000001043Direct
Cytidine deaminase-like0.000000065380.001423Inherited
EF-hand0.56930.001364Inherited
WD40 repeat-like0.0019440.2345Inherited
Immunoglobulin0.00000000040850.2857Inherited
DEATH domain0.0030050.8968Inherited
Mitochondrial carrier0.015770.549Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Calponin-homology domain, CH-domain0.000024230Direct
Capz alpha-1 subunit0.000000017240.00000009293Direct
Capz beta-1 subunit0.000018520.00006965Direct
Cell cycle arrest protein BUB30.00000016780.000001102Direct
Metallothionein0.000000001220.000001602Direct
Profilin (actin-binding protein)0.000000030660.000000186Direct
Retinol binding protein-like0.0000000008050.000000002034Direct
Stathmin0.000001050.000004179Direct
The spindle assembly checkpoint protein mad20.000002510.00000000001972Direct
Mitochondrial carrier0.017730.5824Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAS2 domain-like0Direct
Plakin repeat0Direct
BAR/IMD domain-like0Direct
Calponin-homology domain, CH-domain0Direct
TNF-like0Direct
Spectrin repeat0Direct
Actin depolymerizing proteins0Direct
EB1 dimerisation domain-like0.000000000002322Direct
The spindle assembly checkpoint protein mad20.000000000005863Direct
VHP, Villin headpiece domain0.00000000001165Direct
HR1 repeat0.000000001406Direct
Subunits of heterodimeric actin filament capping protein Capz0.000000001596Direct
SAM/Pointed domain0.000000003045Direct
Concanavalin A-like lectins/glucanases0.000000003329Direct
Thyroglobulin type-1 domain0.00000004619Direct
PH domain-like0.00000007919Direct
Profilin (actin-binding protein)0.0000001198Direct
Lipocalins0.0000001695Direct
RuvA domain 2-like0.0000002262Direct
Composite domain of metallo-dependent hydrolases0.0000002634Direct
Metallothionein0.000000443Direct
Ribosomal protein L130.0000007066Direct
Stathmin0.000002911Direct
Insulin-like0.000003575Direct
Clavaminate synthase-like0.000008817Direct
Sema domain0.00001148Direct
YWTD domain0.0000142Direct
C-terminal, gelsolin-like domain of Sec23/240.00002294Direct
FAT domain of focal adhesion kinase0.00004078Direct
ARM repeat0.00004367Direct
Tex N-terminal region-like0.00004751Direct
Type II DNA topoisomerase0.00005464Direct
RCC1/BLIP-II0.00005616Direct
Telomeric repeat binding factor (TRF) dimerisation domain0.00006792Direct
RUN domain-like0.0000747Direct
LDL receptor-like module0.00009299Direct
Plexin repeat0.0001003Direct
SH3-domain0.0001213Direct
WWE domain0.0001447Direct
F-box domain0.0001868Direct
Rap/Ran-GAP0.000212Direct
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain0.0002885Direct
Arginase/deacetylase0.0003294Direct
DNase I-like0.000398Direct
DPP6 N-terminal domain-like0.0004277Direct
Restriction endonuclease-like0.0005108Direct
Sec7 domain0.0005568Direct
GTPase activation domain, GAP0.0005696Direct
Skp1 dimerisation domain-like0.0006722Direct
TAFH domain-like0.0006722Direct
Kazal-type serine protease inhibitors0.0007213Direct
FYVE/PHD zinc finger0.0009183Direct
EF-hand0.0009761Direct
Hect, E3 ligase catalytic domain0.004536Inherited
PABC (PABP) domain0.1109Inherited
ARID-like0.009748Inherited
Cytidine deaminase-like0.00102Inherited
Chromo domain-like0.6588Inherited
Polo-box domain0.1202Inherited
Kelch motif0.4143Inherited
POZ domain1Inherited
SMAD/FHA domain0.304Inherited
Acyl-CoA N-acyltransferases (Nat)0.995Inherited
Ribosomal protein S5 domain 2-like0.0448Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.3584Inherited
Frizzled cysteine-rich domain0.9017Inherited
ADP-ribosylation0.07977Inherited
N-terminal coiled coil domain from apc0.001522Inherited
Tumor suppressor gene product Apc0.001522Inherited
AraD/HMP-PK domain-like0.001923Inherited
Cap-Gly domain0.008184Inherited
TPR-like0.9112Inherited
Metalloproteases ("zincins"), catalytic domain0.9332Inherited
B-box zinc-binding domain0.01573Inherited
DEATH domain0.7985Inherited
Cystatin/monellin0.09889Inherited
Cyclophilin-like0.2755Inherited
Chaperone J-domain0.2806Inherited
Protein kinase-like (PK-like)0.349Inherited
Nucleic acid-binding proteins0.3104Inherited
SH2 domain1Inherited
DBL homology domain (DH-domain)0.001258Inherited
HMG-box1Inherited
CRAL/TRIO domain0.005832Inherited
Acetyl-CoA synthetase-like0.8562Inherited
RNA-binding domain, RBD1Inherited
Bcl-2 inhibitors of programmed cell death0.1458Inherited
Cysteine-rich DNA binding domain, (DM domain)0.001522Inherited
Cystine-knot cytokines1Inherited
RNI-like0.239Inherited
Cysteine-rich domain0.4216Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.2707Inherited
PDZ domain-like0.002485Inherited
FAD/NAD(P)-binding domain1Inherited
TSP-1 type 1 repeat0.5015Inherited
SOCS box-like0.686Inherited
Cyclin-like0.6433Inherited
Growth factor receptor domain0.2556Inherited
RING/U-box0.8047Inherited
vWA-like0.7657Inherited
PX domain0.6621Inherited
Nuclear receptor ligand-binding domain0.1384Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
Formin homology 2 domain (FH2 domain)0.5718Inherited
Moesin tail domain0.02405Inherited
Family A G protein-coupled receptor-like1Inherited
WD40 repeat-like0.1919Inherited
Metallo-dependent phosphatases0.4903Inherited
Ankyrin repeat0.08103Inherited
Homeodomain-like1Inherited
BRCT domain0.5288Inherited
Periplasmic binding protein-like I0.8101Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Cytokine0.4556Inherited
Metallo-dependent hydrolases0.001311Inherited
MHC antigen-recognition domain0.00248Inherited
Carbonic anhydrase0.01275Inherited
HIT/MYND zinc finger-like0.1677Inherited
Nucleotide cyclase0.2442Inherited
UBC-like0.0184Inherited
Quinoprotein alcohol dehydrogenase-like0.02847Inherited
FKBP-like0.003655Inherited
Tudor/PWWP/MBT0.1367Inherited
Ribonuclease H-like0.9882Inherited
Second domain of FERM0.009046Inherited
E set domains0.2595Inherited
Fibronectin type III0.7501Inherited
Multidrug resistance efflux transporter EmrE0.3238Inherited
Mitochondrial carrier0.4695Inherited
Thiolase-like0.4793Inherited
Ras GEF0.02953Inherited
cAMP-binding domain-like0.1796Inherited
Cupredoxins0.0514Inherited
Galactose-binding domain-like0.03347Inherited
(Phosphotyrosine protein) phosphatases II0.06838Inherited
Immunoglobulin0.2359Inherited
L domain-like0.003761Inherited
Fibrinogen C-terminal domain-like0.01076Inherited
Kringle-like0.2068Inherited
alpha/beta-Hydrolases1Inherited
Ubiquitin-like0.1391Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0Direct
    81383,49899
  • 81383 - F-box domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000000003737Direct
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 0.000000000001651Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0000000001439Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.0000000003179Direct
    48403,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 0.0000000004437Direct
    48371,117839
  • 48371 - ARM repeat
  • 117839 - WWE domain
  • 0.000000001098Direct
    47473,57610
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.000000001827Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.000000002956Direct
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000000002968Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000005864Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000005864Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.000000009797Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00000002592Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00000005073Direct
    50249,55550
  • 50249 - Nucleic acid-binding proteins
  • 55550 - SH2 domain
  • 0.00000005684Direct
    54495,54211
  • 54495 - UBC-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0000000668Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.00000008512Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0.0000001294Direct
    47769,57850
  • 47769 - SAM/Pointed domain
  • 57850 - RING/U-box
  • 0.0000003851Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0.0000007066Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0.0000007066Direct
    49723,140741
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 140741 - RUN domain-like
  • 0.000001074Direct
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000001802Direct
    140741,49723
  • 140741 - RUN domain-like
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.000002359Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.000003504Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.000003644Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.000003709Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.000004081Direct
    54211,56719
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.000004982Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000007724Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.000009714Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0.00001652Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.00001854Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00003432Direct
    63748,57903
  • 63748 - Tudor/PWWP/MBT
  • 57903 - FYVE/PHD zinc finger
  • 0.00003432Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00003592Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0.00004751Direct
    53098,47781
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 0.00004751Direct
    158832,53098
  • 158832 - Tex N-terminal region-like
  • 53098 - Ribonuclease H-like
  • 0.00004751Direct
    47781,50249
  • 47781 - RuvA domain 2-like
  • 50249 - Nucleic acid-binding proteins
  • 0.000112Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.000114Direct
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.000114Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0001378Direct
    47781,47781
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
  • 0.0001733Direct
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002302Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000317Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0003213Direct
    63570,56204
  • 63570 - PABC (PABP) domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.0003654Direct
    49879,57850
  • 49879 - SMAD/FHA domain
  • 57850 - RING/U-box
  • 0.0003654Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0004362Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0004633Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.0004633Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.0004633Direct
    46774,51197
  • 46774 - ARID-like
  • 51197 - Clavaminate synthase-like
  • 0.0006722Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0006722Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0006955Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000803Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.0008497Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.0009644Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.04206Inherited
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.1101Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.02391Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.1903Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2358Inherited
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.01222Inherited
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.001306Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.1222Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.07583Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.001249Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.07823Inherited
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0.1162Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.1349Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1494Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2013Inherited
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.07236Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.03193Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.4379Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.1202Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.6621Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8104Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.8104Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.3599Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.06147Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.7501Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.03063Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.05586Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.005422Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.6565Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.05628Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.05525Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.01877Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.001306Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.006538Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.3095Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1148Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.03365Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    48403,74924,74924
  • 48403 - Ankyrin repeat
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.00000000000004129Direct
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000000002968Direct
    100895,47473,57610
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.00000001356Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.00000003812Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.0000004458Direct
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0000004458Direct
    54534,54534,48452
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.0000005114Direct
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000001074Direct
    47781,50249,55550
  • 47781 - RuvA domain 2-like
  • 50249 - Nucleic acid-binding proteins
  • 55550 - SH2 domain
  • 0.000001074Direct
    140741,49723,140741
  • 140741 - RUN domain-like
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 140741 - RUN domain-like
  • 0.000001074Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.000004081Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.000004081Direct
    55874,54211,56719
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 56719 - Type II DNA topoisomerase
  • 0.000004982Direct
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000004982Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000007724Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000007724Direct
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000008536Direct
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00002015Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00003432Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00003432Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.00003432Direct
    63748,57903,57903
  • 63748 - Tudor/PWWP/MBT
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.00003432Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00003592Direct
    158832,53098,47781
  • 158832 - Tex N-terminal region-like
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 0.00004751Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.00005189Direct
    47781,47781,50249
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
  • 50249 - Nucleic acid-binding proteins
  • 0.000112Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.000114Direct
    53098,47781,47781
  • 53098 - Ribonuclease H-like
  • 47781 - RuvA domain 2-like
  • 47781 - RuvA domain 2-like
  • 0.0001402Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000143Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0004633Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0004633Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0005768Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.0009644Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2084Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2358Inherited
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.01222Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4085Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.001522Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.02225Inherited
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.05215Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.02156Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03193Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.06655Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8104Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1796Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.9081Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001164Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02834Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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