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Biological Process (BP): epithelium development

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   developmental process [GO:0032502] <12>(88|106) (562|634|415)
+ + 2:   anatomical structure development [GO:0048856] <208>(86|100) (540|615|406)
+ 1:   tissue development [GO:0009888] <29>(31|30) (318|310|205)
0:   epithelium development [GO:0060429] <22>(14|14) (241|223|128)
- 1:   epithelial cell differentiation [GO:0030855] <25>(6|6) (133|112|74)
- 1:   morphogenesis of an epithelium [GO:0002009] <22>(7|7) (175|159|93)
- 1:   imaginal disc development [GO:0007444] <12>(1|1) (92|62|38)
- 1:   lung epithelium development [GO:0060428] <6>(0|0) (1|0|0)
- 1:   embryonic heart tube development [GO:0035050] <5>(0|1) (45|30|19)
- 1:   kidney epithelium development [GO:0072073] <5>(1|1) (40|25|16)
- 1:   endothelium development [GO:0003158] <4>(0|1) (34|25|24)
- 1:   somite development [GO:0061053] <4>(0|0) (30|31|28)
- 1:   mammary gland epithelium development [GO:0061180] <3>(1|1) (11|8|4)
- 1:   neural tube development [GO:0021915] <3>(0|0) (49|22|9)
- 1:   renal tubule development [GO:0061326] <3>(1|1) (36|16|2)
- 1:   neural plate development [GO:0001840] <2>(0|0) (5|5|9)
- 1:   pericardium development [GO:0060039] <2>(0|0) (9|4|1)
- 1:   skin epidermis development [GO:0098773] <2>(0|0) (6|5|2)
- 1:   epithelium regeneration [GO:1990399] <1>(0|0) (4|2|1)
- 1:   heart rudiment development [GO:0003313] <1>(0|0) (6|9|8)
- 1:   otic vesicle development [GO:0071599] <1>(0|0) (19|8|3)
- 1:   oviduct epithelium development [GO:0035846] <1>(1|1) (3|1|0)
- 1:   seminal vesicle epithelium development [GO:0061108] <1>(0|0) (0|0|0)
- 1:   ureter urothelium development [GO:0072190] <1>(0|0) (1|1|0)
- 1:   retinal pigment epithelium development [GO:0003406](1|1) (5|4|2)
- 1:   urethra epithelium development [GO:0061071](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
P-loop containing nucleoside triphosphate hydrolases00.0000000005331Direct
PDZ domain-like0.00022180Direct
Cytokine0.0014520.2854Inherited
Trypsin-like serine proteases0.64461Inherited
Metallo-dependent phosphatases0.040781Inherited
(Phosphotyrosine protein) phosphatases II0.11230.006011Inherited
Cysteine proteinases0.062450.3352Inherited
4-helical cytokines0.87310.1063Inherited
HLH, helix-loop-helix DNA-binding domain0.045350.02199Inherited
Cu,Zn superoxide dismutase-like0.04290.2536Inherited
POZ domain0.00027620.9263Inherited
Acid proteases0.000000028810.1703Inherited
Homeodomain-like0.95040.0713Inherited
L domain-like0.017741Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
G proteins00Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0.000011980.00003898Direct
Fibroblast growth factors (FGF)0.0011360.2889Inherited
Eukaryotic proteases0.59550.9107Inherited
Protein serine/threonine phosphatase0.00024520.4611Inherited
Papain-like0.068950.07576Inherited
Long-chain cytokines0.9640.007255Inherited
Isoprenyl diphosphate synthases0.0067270.2149Inherited
HLH, helix-loop-helix DNA-binding domain0.038980.01885Inherited
Cu,Zn superoxide dismutase-like0.036320.2295Inherited
BTB/POZ domain0.00018970.8866Inherited
Pepsin-like0.0000000044950.07658Inherited
Paired domain00.008939Inherited
Ngr ectodomain-like0.00057910.4473Inherited


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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DPY module0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
PDZ domain-like0Direct
A heparin-binding domain0Direct
RILP dimerisation region0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.000000000008381Direct
BRK domain-like0.00000000002059Direct
Ubiquitin-like0.00000000008983Direct
p53 tetramerization domain0.000000000127Direct
P-loop containing nucleoside triphosphate hydrolases0.0000000003104Direct
RGC domain-like0.000000000478Direct
SH3-domain0.0000000006294Direct
DNA-binding protein LAG-1 (CSL)0.000000001875Direct
HR1 repeat0.000000002693Direct
A middle domain of Talin 10.00000001395Direct
Geminin coiled-coil domain0.00000001395Direct
PH domain-like0.00000002304Direct
DBL homology domain (DH-domain)0.00000004584Direct
BAR/IMD domain-like0.0000002532Direct
Second domain of FERM0.0000005024Direct
Glucocorticoid receptor-like (DNA-binding domain)0.000001347Direct
Moesin tail domain0.00000135Direct
Stathmin0.000002104Direct
Cadherin-like0.000002834Direct
Polo-box domain0.000005194Direct
VHL0.000006224Direct
GAS2 domain-like0.000006407Direct
GTPase activation domain, GAP0.000006495Direct
Kix domain of CBP (creb binding protein)0.000009785Direct
SPOC domain-like0.00001016Direct
I/LWEQ domain0.00001127Direct
Putative DNA-binding domain0.00002504Direct
N-terminal coiled coil domain from apc0.00006684Direct
Tumor suppressor gene product Apc0.00006684Direct
Intermediate filament protein, coiled coil region0.0002137Direct
GCM domain0.0002142Direct
alpha-catenin/vinculin-like0.0002949Direct
SAND domain-like0.0003771Direct
FAT domain of focal adhesion kinase0.0004733Direct
TAZ domain0.0004733Direct
Formin homology 2 domain (FH2 domain)0.000479Direct
Kazal-type serine protease inhibitors0.0005003Direct
SAM/Pointed domain0.0005505Direct
Frizzled cysteine-rich domain0.0005505Direct
Cytidine deaminase-like0.7063Inherited
Midkine0.1911Inherited
Immunoglobulin1Inherited
ARID-like0.5441Inherited
Tudor/PWWP/MBT0.4664Inherited
FF domain0.01353Inherited
Multidrug efflux transporter AcrB transmembrane domain0.5483Inherited
HMG-box0.001498Inherited
lambda repressor-like DNA-binding domains0.7752Inherited
SRF-like1Inherited
CAD & PB1 domains0.3841Inherited
Cystine-knot cytokines1Inherited
Kelch motif0.775Inherited
Ankyrin repeat0.005521Inherited
BRCT domain0.3497Inherited
Bet v1-like1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
TPR-like1Inherited
Cullin repeat-like0.05534Inherited
Cullin homology domain0.4882Inherited
Kringle-like0.1414Inherited
Integrin alpha N-terminal domain1Inherited
FnI-like domain0.7584Inherited
Caspase-like0.09377Inherited
gamma-Crystallin-like0.3232Inherited
TIMP-like0.006645Inherited
Class II aaRS ABD-related0.6549Inherited
TSP-1 type 1 repeat0.8573Inherited
Class II aaRS and biotin synthetases1Inherited
Heparin-binding domain from vascular endothelial growth factor0.05015Inherited
PUA domain-like0.8531Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase1Inherited
HD-domain/PDEase-like0.06515Inherited
GAF domain-like0.1005Inherited
TNF receptor-like0.7773Inherited
Ras GEF0.07416Inherited
cAMP-binding domain-like0.8616Inherited
DEATH domain0.2071Inherited
TB module/8-cys domain0.06298Inherited
Notch domain0.9689Inherited
FAS1 domain1Inherited
Galactose-binding domain-like0.9139Inherited
PYP-like sensor domain (PAS domain)0.0195Inherited
FAD-linked reductases, C-terminal domain1Inherited
ThrRS/AlaRS common domain0.0266Inherited
TGS-like0.08239Inherited
Troponin coil-coiled subunits1Inherited
IP3 receptor type 1 binding core, domain 20.8699Inherited
V-type ATP synthase subunit C0.006816Inherited
Fibrinogen C-terminal domain-like1Inherited
Cysteine proteinases0.279Inherited
Homeodomain-like0.05591Inherited
Metallo-dependent phosphatases1Inherited
GroEL equatorial domain-like0.2835Inherited
GroEL apical domain-like0.677Inherited
UBA-like0.6973Inherited
PGBD-like0.07137Inherited
Hemopexin-like domain0.1414Inherited
BPTI-like0.4456Inherited
p53-like transcription factors0.2998Inherited
STAT1Inherited
Transcription factor STAT-4 N-domain1Inherited
Doublecortin (DC)0.1415Inherited
SNARE fusion complex0.9728Inherited
E set domains0.001412Inherited
PP2C-like1Inherited
Cyclin-like0.4762Inherited
C-type lectin-like1Inherited
Calcium-dependent phosphotriesterase0.7288Inherited
Thyroglobulin type-1 domain0.2591Inherited
ALDH-like0.7957Inherited
WD40 repeat-like0.6977Inherited
4-helical cytokines0.08433Inherited
Complement control module/SCR domain1Inherited
Acid proteases0.1373Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
Fibronectin type III0.9768Inherited
CCHHC domain0.001084Inherited
Eferin C-derminal domain-like0.005545Inherited
C-terminal domain of adenylylcyclase associated protein0.05145Inherited
N-terminal domain of adenylylcyclase associated protein, CAP0.05145Inherited
Snake toxin-like1Inherited
Mitochondrial carrier1Inherited
Chromo domain-like0.001714Inherited
Regulator of G-protein signaling, RGS0.001347Inherited
Protein serine/threonine phosphatase 2C, C-terminal domain0.003824Inherited
KA1-like0.1136Inherited
Spermadhesin, CUB domain0.9836Inherited
PAH2 domain0.008659Inherited
N-terminal domain of cbl (N-cbl)0.003824Inherited
Voltage-gated potassium channels0.04734Inherited
Quinoprotein alcohol dehydrogenase-like0.9378Inherited
TATA-box binding protein-like0.1147Inherited
DNA-glycosylase0.3231Inherited
Connexin430.05145Inherited
MIR domain0.8699Inherited
beta-beta-alpha zinc fingers0.1613Inherited
Hedgehog/intein (Hint) domain0.001452Inherited
Hedgehog/DD-peptidase0.001452Inherited
Trypsin-like serine proteases1Inherited
Prefoldin0.006645Inherited
Serine protease inhibitors0.004371Inherited
E2F-DP heterodimerization region0.1695Inherited
Transglutaminase, two C-terminal domains0.004071Inherited
Dimerization cofactor of HNF-1 alpha0.1248Inherited
F-box domain1Inherited
SEA domain0.7353Inherited
ARM repeat0.0266Inherited
Orange domain-like0.04046Inherited
Mib/herc2 domain-like0.004703Inherited
NHL repeat0.002273Inherited
B-box zinc-binding domain0.6373Inherited
Eukaryotic type KH-domain (KH-domain type I)0.006606Inherited
Nuclear receptor ligand-binding domain0.04952Inherited
Myosin rod fragments0.9638Inherited
Arginase/deacetylase0.6004Inherited
HAD-like1Inherited
Calcium ATPase, transmembrane domain M0.9312Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.3139Inherited
Calcium ATPase, transduction domain A0.9643Inherited
Tropomyosin1Inherited
Cysteine-rich domain0.005141Inherited
(Phosphotyrosine protein) phosphatases II0.004429Inherited
Concanavalin A-like lectins/glucanases1Inherited
Protein kinase-like (PK-like)1Inherited
G protein-binding domain0.008659Inherited
SMAD/FHA domain0.1882Inherited
FKBP-like0.8639Inherited
WW domain0.01277Inherited
Metalloproteases ("zincins"), catalytic domain0.01183Inherited
alpha/beta-Hydrolases1Inherited
SH2 domain0.3105Inherited
SOCS box-like0.04584Inherited
FYVE/PHD zinc finger1Inherited
Nucleotide cyclase1Inherited
Integrin domains1Inherited
Spectrin repeat1Inherited
Plakin repeat0.05622Inherited
EF-hand1Inherited
Calponin-homology domain, CH-domain1Inherited
EGF/Laminin0.2082Inherited
Growth factor receptor domain0.1531Inherited
Bromodomain1Inherited
"Winged helix" DNA-binding domain0.0127Inherited
Leucine zipper domain0.8435Inherited
POZ domain0.8279Inherited
SNF-like0.148Inherited
Chitinase insertion domain0.008659Inherited
RNA-binding domain, RBD0.551Inherited
Heme-dependent peroxidases0.9082Inherited
Ypt/Rab-GAP domain of gyp1p0.03025Inherited
Tetraspanin0.1327Inherited
SAP domain0.0314Inherited
Actin depolymerizing proteins0.763Inherited
beta-sandwich domain of Sec23/240.1183Inherited
A DNA-binding domain in eukaryotic transcription factors0.2024Inherited
L27 domain0.001374Inherited
CRAL/TRIO domain0.4515Inherited
Blood coagulation inhibitor (disintegrin)0.2551Inherited
Toll/Interleukin receptor TIR domain0.6635Inherited
Cdc48 domain 2-like0.04074Inherited
ADC-like0.2791Inherited
TRAF domain-like0.275Inherited
Hairpin loop containing domain-like0.4181Inherited
Rap/Ran-GAP0.04313Inherited
Family A G protein-coupled receptor-like1Inherited
L domain-like1Inherited
Protease propeptides/inhibitors0.9731Inherited
Subtilisin-like1Inherited
NTF2-like0.7403Inherited
Dihydrofolate reductase-like0.1762Inherited
Glycerol-3-phosphate (1)-acyltransferase0.35Inherited
DNA-binding domain1Inherited
Cu,Zn superoxide dismutase-like0.2083Inherited
vWA-like1Inherited
Zn-finger domain of Sec23/241Inherited
DHS-like NAD/FAD-binding domain0.923Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.3454Inherited
dsRNA-binding domain-like0.823Inherited
LuxS/MPP-like metallohydrolase0.4762Inherited
Transducin (alpha subunit), insertion domain0.016Inherited
Prion-like0.02984Inherited
Leukotriene A4 hydrolase N-terminal domain0.5053Inherited
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.003061Inherited
SET domain1Inherited
Plexin repeat1Inherited
Sema domain1Inherited
Aminoacid dehydrogenase-like, N-terminal domain0.9382Inherited
LDL receptor-like module1Inherited
Clavaminate synthase-like1Inherited
HIT/MYND zinc finger-like0.3797Inherited
Plus3-like0.6802Inherited
Cysteine-rich DNA binding domain, (DM domain)0.02114Inherited
Insulin-like1Inherited
HLH, helix-loop-helix DNA-binding domain0.01669Inherited
Cytokine0.2356Inherited
SMAD MH1 domain0.08989Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    81995,55785
  • 81995 - beta-sandwich domain of Sec23/24
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    56491,109843
  • 56491 - A heparin-binding domain
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0Direct
    57184,90148
  • 57184 - Growth factor receptor domain
  • 90148 - DPY module
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0Direct
    81995,54236
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 0Direct
    57184,82153
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 0Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0Direct
    48403,48452
  • 48403 - Ankyrin repeat
  • 48452 - TPR-like
  • 0.0000000000004698Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000000000001069Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.000000000002953Direct
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.000000000003367Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.000000000008127Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.000000000008381Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0.000000000127Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0000000001975Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000000004872Direct
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.000000001875Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0.000000003247Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.000000004142Direct
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.000000007793Direct
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.00000001395Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.00000002137Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.00000002137Direct
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00000003948Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00000004232Direct
    47576,47576
  • 47576 - Calponin-homology domain, CH-domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0.0000001521Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0000002055Direct
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.0000002309Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0.0000003657Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000008024Direct
    48403,57903
  • 48403 - Ankyrin repeat
  • 57903 - FYVE/PHD zinc finger
  • 0.000000844Direct
    57610,47473
  • 57610 - Thyroglobulin type-1 domain
  • 47473 - EF-hand
  • 0.000000844Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.000001194Direct
    56436,82153
  • 56436 - C-type lectin-like
  • 82153 - FAS1 domain
  • 0.000001723Direct
    51905,47576
  • 51905 - FAD/NAD(P)-binding domain
  • 47576 - Calponin-homology domain, CH-domain
  • 0.000002034Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.00000273Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.000004302Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000006837Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000009234Direct
    47576,50044
  • 47576 - Calponin-homology domain, CH-domain
  • 50044 - SH3-domain
  • 0.00001295Direct
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.00001588Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.00002194Direct
    47220,109885
  • 47220 - alpha-catenin/vinculin-like
  • 109885 - I/LWEQ domain
  • 0.00002194Direct
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.00002417Direct
    47473,50729
  • 47473 - EF-hand
  • 50729 - PH domain-like
  • 0.00002417Direct
    57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0.00003208Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.00003939Direct
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0.00004567Direct
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0.00008602Direct
    48350,54236
  • 48350 - GTPase activation domain, GAP
  • 54236 - Ubiquitin-like
  • 0.00009796Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0.0001375Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0001404Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0001569Direct
    101288,101288
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0.0001823Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.0001823Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.0002404Direct
    55186,55681
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0002471Direct
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.0002956Direct
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.0003852Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.0004271Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0004673Direct
    160481,160481
  • 160481 - BRK domain-like
  • 160481 - BRK domain-like
  • 0.0004805Direct
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.0006336Direct
    54534,47473
  • 54534 - FKBP-like
  • 47473 - EF-hand
  • 0.0007142Direct
    54277,50156
  • 54277 - CAD & PB1 domains
  • 50156 - PDZ domain-like
  • 0.0008643Direct
    57288,57288
  • 57288 - Midkine
  • 57288 - Midkine
  • 0.2551Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.6004Inherited
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 1Inherited
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.6829Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.973Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.2939Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.1695Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.02114Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.2551Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.004424Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.02114Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.008659Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.6359Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.004244Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.7223Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.7809Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.2115Inherited
    49265,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 0.003554Inherited
    57603,49265
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.005545Inherited
    57440,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.005545Inherited
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.005545Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.002273Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 1Inherited
    81324,47473
  • 81324 - Voltage-gated potassium channels
  • 47473 - EF-hand
  • 0.004703Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.1601Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.8699Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 1Inherited
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0.04246Inherited
    50978,50969
  • 50978 - WD40 repeat-like
  • 50969 - YVTN repeat-like/Quinoprotein amine dehydrogenase
  • 0.1943Inherited
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 1Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.7353Inherited
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.005545Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.9019Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.9935Inherited
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.9571Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.192Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited
    100895,48726
  • 100895 - Kazal-type serine protease inhibitors
  • 48726 - Immunoglobulin
  • 0.001014Inherited
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0.003824Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.009377Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.7353Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.8699Inherited
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.01464Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 1Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.2514Inherited
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.2628Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.07137Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.08081Inherited
    48592,52029
  • 48592 - GroEL equatorial domain-like
  • 52029 - GroEL apical domain-like
  • 0.1943Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.4653Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.4973Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 1Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 1Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 1Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.05015Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.08593Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.3418Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.1986Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.008084Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.06734Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 1Inherited
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.2083Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.05043Inherited
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.003824Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 1Inherited
    55486,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 0.003554Inherited
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.6792Inherited
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.5812Inherited
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.002273Inherited
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.01354Inherited
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.02114Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.01408Inherited
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0.004703Inherited
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.003061Inherited
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.003061Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.003824Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.05752Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05752Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.3358Inherited
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.001339Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.2474Inherited
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.001452Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.001272Inherited
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.009758Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.1695Inherited
    57424,50494
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0.6802Inherited
    82671,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 0.6802Inherited
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0.00361Inherited
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.004071Inherited
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.004071Inherited
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.02373Inherited
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0.6802Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.04046Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.001665Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 1Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.5208Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.3139Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.09564Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.01277Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.008659Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.8613Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 1Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.5395Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2669Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02496Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.007345Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.403Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.2083Inherited
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.008659Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.1222Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.00169Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.206Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.6359Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.8401Inherited
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.005689Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.2551Inherited
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01339Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.02632Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.9836Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.09915Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.06198Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.6983Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.8018Inherited
    100909,49899
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7353Inherited
    46955,63763
  • 46955 - Putative DNA-binding domain
  • 63763 - SAND domain-like
  • 0.005545Inherited
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.1943Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.7773Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.8114Inherited
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.01354Inherited
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.1248Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 1Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.01466Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.6792Inherited
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.6802Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 1Inherited
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.3739Inherited
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.02373Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01545Inherited
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.05942Inherited
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.002156Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.01339Inherited
    52540,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 0.002404Inherited
    160481,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001014Inherited
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.002404Inherited
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.677Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.1989Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 1Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 1Inherited
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 1Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,54236,50729
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    57184,57184,82153
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 0Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0Direct
    57184,82153,82153
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000000000003293Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.000000000001069Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.000000000003367Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0000000001975Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0000000004191Direct
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.000000007793Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.000000008806Direct
    46689,46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.00000001029Direct
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00000001395Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.00000002137Direct
    48403,48403,57903
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 57903 - FYVE/PHD zinc finger
  • 0.0000003657Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000006362Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000008024Direct
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.0000008024Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000008024Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.0000008779Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.000002538Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.000005615Direct
    57196,100895,47473
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.00001295Direct
    47576,50044,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.00001295Direct
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00001865Direct
    57196,49854,57196
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.00002194Direct
    50044,46966,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00002417Direct
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00002417Direct
    49854,49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.00003208Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00003313Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00003939Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.00005426Direct
    49899,57196,57184
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00006684Direct
    81271,55186,55681
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.00008929Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00009741Direct
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0.00009796Direct
    47220,47220,109885
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 109885 - I/LWEQ domain
  • 0.0001506Direct
    57184,100895,48726
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 48726 - Immunoglobulin
  • 0.0001823Direct
    101288,101288,50156
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.0001823Direct
    55186,55681,52954
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.000205Direct
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.000296Direct
    52540,48452,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0003071Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0003521Direct
    47370,47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.0007142Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9713Inherited
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.003824Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.7809Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.9314Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.01023Inherited
    49265,57603,57603
  • 49265 - Fibronectin type III
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.003554Inherited
    57440,57440,57603
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 0.005545Inherited
    57440,57603,57603
  • 57440 - Kringle-like
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.005545Inherited
    57603,57603,57440
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0.005545Inherited
    57603,57603,49265
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 49265 - Fibronectin type III
  • 0.005545Inherited
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.005545Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 1Inherited
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 1Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1248Inherited
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.08013Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.9805Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.9873Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.9372Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.7353Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.01277Inherited
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 1Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.5702Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.08081Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 1Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 1Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.06237Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.008429Inherited
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.00185Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.3717Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.7794Inherited
    55486,49854,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.08013Inherited
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.6792Inherited
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.002273Inherited
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.01354Inherited
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.02114Inherited
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.03297Inherited
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.003061Inherited
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.003061Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05752Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05752Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.1707Inherited
    82671,49854,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.6802Inherited
    57424,57424,50494
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0.6802Inherited
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.00361Inherited
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0.004071Inherited
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.01815Inherited
    52047,52058,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.1943Inherited
    49854,57424,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.6802Inherited
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0.6802Inherited
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.823Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.3139Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05166Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 1Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.004904Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.278Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.09511Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01661Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.403Inherited
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.005689Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01213Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.08593Inherited
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01127Inherited
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0123Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.04955Inherited
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.001638Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 1Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.587Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.8018Inherited
    82109,100909,49899
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7353Inherited
    54928,54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.002023Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.7773Inherited
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.1248Inherited
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.05942Inherited
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.001509Inherited
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0.007688Inherited
    160481,52540,52540
  • 160481 - BRK domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001014Inherited
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.001014Inherited
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.002404Inherited
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.003554Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001138Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited


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